标签： Cyanine3

Cy3 azide,Cy3 叠氮化物

Cy3 azide,Cy3 叠氮化物,用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

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  • Cyanine3 azide

Cyanine3 azide

标签：Cyanine3, Cy3,Azides, Microscopy
货号 规格 价格 货期
11030 100 uL, 10 mM/DMSO 110.00$ in stock
31030 500 uL, 10 mM/DMSO 210.00$ in stock
41030 1 mL, 10 mM/DMSO 410.00$ in stock
A1030 1 mg 110.00$ in stock
B1030 5 mg 210.00$ in stock
C1030 10 mg 310.00$ in stock
D1030 25 mg 410.00$ in stock
E1030 50 mg 695.00$ in stock
F1030 100 mg 1190.00$ in stock

Cyanine3 dye azide for Click Chemistry, an analog of Cy3® azide. Cy3® is one of the most broadly used fluorophores which can be detected by various fluorometers, imagers, and microscopes. Due to inherently high extinction coefficient, Cyanine3 is also easily detected by naked eye on gels, and in solution. This is non-sulfonated dye which requires organic co-solvent (DMF, DMSO, or other) for efficient labeling in water. Water-soluble version of this reagent is also available.

Product is available both as solid compound, and as 10 mM solution in DMSO which is ready to use in our recommended protocol.

Cyanine3 fluorescent properties are identical to Cy3®, and similar to DyLight 549.

用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

产品既可以作为固体化合物提供，也可以作为 10 mM DMSO 溶液提供，可在我们推荐的方案中使用。

Cyanine3 荧光特性与 Cy3® 相同，与 DyLight 549 相似。

Cy3 absorbance and emission spectra

Cyanine3 azide

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PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP（苯乙炔基芘），用于 Click-Chemistry 标记的多环芳烃荧光染料。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

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General properties

Appearance: red powder / solution 红粉/溶液
Molecular weight: 575.19
CAS number: 1167421-28-4 (chloride)
Molecular formula: C33H43N6OCl
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (40 mg/L = 60 uM)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  2. Tan, M.S.Y.; Davison, D.; Sanchez, M.I.; Anderson, B.M.; Howell, S.; Snijders, A.; Edgington-Mitchell, L.E.; Deu, E. Novel broad-spectrum activity-based probes to profile malarial cysteine proteases. PLoS One, 2020, 15(1), e0227341. doi: 10.1371/journal.pone.0227341
  3. Saqr, A.; Vakili, M.R.; Huang, Y.-H.; Lai, R.; Lavasanifar, A. Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma. ACS Omega, 2019, 4(20), 18867–18879. doi: 10.1021/acsomega.9b02910
  4. Morimoto, K.; Cole, K.S.; Kourelis, J.; Witt, C.H.; Brown, D.; Krahn, D.; Stegmann, M.; Kaschani, F.; Kaiser, M.; Burton, J.; Mohammed, S.; Yamaguchi-Shinozaki, K.; Weerapana, E.; van der Hoorn, R.A.L. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology, 2019, 180(4), 1848–1859. doi: 10.1104/pp.19.00481
Cy® is a trademark of Cytiva.

lumiprobe -Cyanine3B carboxylic acid,2321-1mg

lumiprobe -Cyanine3B carboxylic acid,2321-1mg,Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

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  • Carboxylic acids
  • Cyanine3B carboxylic acid

Cyanine3B carboxylic acid

Cyanine3, Carboxylic acids, sulfo-Cyanine3,Cy3
Cat. # Quantity Price Lead time
2321-1mg 1 mg 110.00$ 8 days
2321-5mg 5 mg 149.00$ 8 days
2321-25mg 25 mg 690.00$ 8 days
2321-50mg 50 mg 1290.00$ 8 days
2321-100mg 100 mg 2450.00$ 8 days

General properties

Appearance: dark red powder
Molecular weight: 560.66
Molecular formula: C31H32N2O6S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Cyanine3B carboxylic acid

Cyanine3 NHS ester minimal dye

Cyanine3 NHS ester minimal dye,用于蛋白质标记的 Cy3 NHS 酯染料和 Cy3® 最小染料的类似物。该试剂经过特殊量化——每包含有指定量的 NHS 酯，数量变化在 10% 以内。

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  • Cyanine3 NHS ester minimal dye

Cyanine3 NHS ester minimal dye

标签：Cyanine3,NHS esters,Protein labeling
Cat. # Quantity Price Lead time
1B041 5 nmol 85.00$ in stock

2B041 10 nmol 140.00$ in stock

3B041 25 nmol 210.00$ in stock

Cyanine3 NHS ester dye for protein labeling, and analog of Cy3® minimal dye.

This reagent is specially quantified – each package contains specified amount of NHS ester with quantity variation within 10%.

用于蛋白质标记的 Cy3 NHS 酯染料和 Cy3® 最小染料的类似物。

该试剂经过特殊量化——每包含有指定量的 NHS 酯，数量变化在 10% 以内。

Cy3 NHS ester minimal dye相关产品

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

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Cyanine5 NHS ester minimal dye

Cy5 NHS ester minimal dye for protein labeling.

Cy5 NHS 酯最小染料用于蛋白质标记。

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Sulfo-Cyanine7.5 NHS ester

A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.

一种用于体内成像应用的水溶性近红外发射染料。 Sulfo-Cy7.5 是吲哚菁绿 (ICG) 的类似物，具有更高的发射量子产率，并包含一个连接臂。

Cyanine3 NHS ester minimal dye Add this product to your cart and
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General properties

Appearance: red solid
Quality control: NMR 1H, HPLC-MS, functional testing
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
Emission maximum, nm: 570
CF260: 0.04
CF280: 0.09

相关文献：

  1. Lobov, A.A.; Babkina, I.Y.; Danilov, L.G.; Masharskiy, A.E.; Predeus, A.V.; Mikhailova, N.A.; Granovitch, A.I.; Maltseva, A.L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina fabalis and L. obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  2. Nixon, B.; Anderson, A.L.; Bromfield, E.G.; Martin, J.H.; Cafe, S.L.; Skerrett-Byrne, D.A.; Dun, M.D.; Eamens, A.L.; De Iuliis, G.N.; Johnston, S.D. Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility. Reproduction, Fertility, and Development, 2021, 33(9), 530–539. doi: 10.1071/RD20204
  3. Shikov, A.E.; Malovichko, Y.V.; Lobov, A.A.; Belousova, M.E.; Nizhnikov, A.A.; Antonets, K.S. The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification of Bacillus thuringiensis. International Journal of Molecular Sciences, 2021, 22(5), 2244. doi: 10.3390/ijms22052244
  4. Serteyn, L.; Bosquee, E.; Delatour, A.; Rubio-Melendez, M.E.; Vega-Muñoz, K.V.; Ramirez, C.C.; Francis, F. Multi-approach comparative study of the two most prevalent genotypes of pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) in Chile. Entomological Science, 2021, 24(1), 55–67. doi: 10.1111/ens.12436

Cy® is a trademark of GE Healthcare.

Purchase of these products does not imply transfer of license to perform methods patented by Carnegie Mellon University and covered by US patents 6,043,025, 6,127,134, 6,246,190, 7566,544, and 7,598,047 “Difference gel electrophoresis using matched multiple dyes” and family members in Australia, Canada, Europe and Japan.

Cyanine3 NHS ester minimal dye

购买这些产品并不意味着转让执行卡内基梅隆大学专利的方法并受美国专利 6,043,025、6,127,134、6,246,190、7566,544 和 7,598,047“使用匹配的多种染料的差异凝胶电泳”和澳大利亚的家庭成员的许可， 加拿大、欧洲和日本。

Cyanine3 amine

Cyanine3 amine,Cy3胺是一种含有游离氨基的功能化花青染料。 Cyanine3 是 Cy3® 的类似物

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  • Cyanine3 amine

Cyanine3 amine

标签：Cyanine3, Cy3, Amines
货号 规格 价格 货期
110C0 1 mg 110.00$ 5 days
210C0 5 mg 210.00$ in stock
410C0 25 mg 410.00$ in stock
510C0 50 mg 695.00$ in stock
610C0 100 mg 1190.00$ in stock

Cyanine3 amine is a functionalized cyanine dye containing a free amino group. Cyanine3 is an analog of Cy3®.

Amino group of this reagent can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

The amino dye is supplied in salt form, and possesses some aqueous solubility.

Cy3胺是一种含有游离氨基的功能化花青染料。 Cyanine3 是 Cy3® 的类似物。

该试剂的氨基可与 NHS 酯、羧基（碳二亚胺活化后）和环氧化物等反应基团结合。

氨基染料以盐的形式提供，并具有一定的水溶性。

Cyanine3 absorption and emission spectra

Cyanine3 amine

Cyanine3 amine相关产品

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cyanine5.5 染料衍生物。

Cyanine7.5 hydrazide

Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.

用酰肼部分功能化的近红外荧光团。 对羰基化合物具有反应性，可用于标记糖类和高碘酸盐氧化后的抗体。

General properties

Appearance: red powder  红色粉末
Molecular weight: 627.73
CAS number: 2247688-56-6
Molecular formula: C36H52Cl2N4O
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[3-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​2H-​indol-​2-​ylidene)​-​1-​propen-​1-​yl]​-​3,​3-​dimethyl-​, chloride, hydrochloride (1:1:1)
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Wang, Y.; van Steenbergen, M.J.; Beztsinna, N.; Shi, Y.; Lammers, T.; van Nostrum, C.F.; Hennink, W.E. Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery. Journal of Controlled Release, 2020, 328, 970–984. doi: 10.1016/j.jconrel.2020.09.013
  2. Hifni, B.; Khan, M.; Devereux, S.J.; Byrne, M.H.; Quinn, S.J.; Simpson, J.C. Investigation of the cellular destination of fluorescently labelled carbon nanohorns in cultured cells. ACS Applied Bio Materials, 2020, 3(10), 6790–6801. doi: 10.1021/acsabm.0c00748
  3. Teng, F.; Wu, X.; Libera, M.R. Chemical Orthogonality in Surface-Patterned Poly(ethylene glycol) Microgels. Langmuir, 2020, 36(35), 10622–10627. doi: 10.1021/acs.langmuir.0c02172
  4. Zaw Thin, M.; Allan, H.; Bofinger, R.; Kostelec, T.D.; Guillaume, S.; Connell, J.J.; Patrick, P.S.; Hailes, H.C.; Tabor, A.B.; Lythgoe, M.F.; Stuckey, D.J.; Kalber, T.L. Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours. Nanoscale, 2020, 12(31), 16570–16585. doi: 10.1039/d0nr03237a
Cy® is a trademark of GE Healthcare.

Cyanine3 carboxylic acid

Cyanine3 carboxylic acid,游离Cyanine3 羧酸（Cy3® 羧酸类似物），非活化染料。 非磺化试剂，在有机溶剂中溶解性好，水溶性有限。 该染料可用作非反应性荧光团，用于对照实验和校准。

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  • Cyanine3 carboxylic acid

Cyanine3 carboxylic acid

标签：Cy3, Cyanine3,Carboxylic acids
货号 规格 价格 货期
11090 1 mg 110.00$ in stock
21090 5 mg 210.00$ in stock
41090 25 mg 410.00$ in stock
51090 50 mg 695.00$ in stock
61090 100 mg 1190.00$ in stock

Free Cyanine3 carboxylic acid (Cy3® carboxylic acid analog), non-activated dye. Non-sulfonated reagent, with good solubility in organic solvents, and limited aquous solubility. The dye can be used as a non-reactive fluorophore, for control experiments, and for calibration.

For coupling with amines, and labeling, consider using Cyanine3 NHS ester, or water-soluble sulfo-Cyanine3 NHS ester.

游离Cyanine3 羧酸（Cy3® 羧酸类似物），非活化染料。 非磺化试剂，在有机溶剂中溶解性好，水溶性有限。 该染料可用作非反应性荧光团，用于对照实验和校准。

对于与胺偶联和标记，请考虑使用 Cyanine3 NHS 酯或水溶性磺基-Cyanine3 NHS 酯。

Cyanine3 absorbance and emission spectra

Cyanine3 carboxylic acid

Cyanine3 carboxylic acid相关产品

FAM NHS ester, 6-isomer

Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.

荧光素的活化 N-羟基琥珀酰亚胺酯 (FAM)，纯 6-异构体。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cy5.5 染料衍生物。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

General properties

Appearance: red powder 红色粉末
Molecular weight: 493.08
CAS number: 1361402-15-4 (inner salt), 1032678-01-5 (chloride), 1251915-29-3 (iodide)
Molecular formula: C30H37ClN2O2
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), poorly soluble in water (1.8 g/L = 4.0 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Nam, J.; Lim, H.-K.; Kim, N.H.; Park, J.K.; Kang, E.S.; Kim, Y.-T.; Heo, C.; Lee, O.-S.; Kim, S.-G.; Yun, W.S.; Suh, M.; Kim, Y.H. Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through Three-Dimensional Electrical Network. ACS Nano, 2020, 14(1), 664–675. doi: 10.1021/acsnano.9b07396
  2. Deshmukh, R.; Biehs, S.-A.; Khwaja, E.; Galfsky, T.; Agarwal, G.S.; Menon, V.M. Long-range resonant energy transfer using optical topological transitions in metamaterials. ACS Photonics, 2018, 5(7), 2737–2741. doi: 10.1021/acsphotonics.8b00484
  3. Mattila, J.T.; Beaino, W.; Maiello, P.; Coleman, M.T.; White, A.G.; Scanga, C.A.; Flynn, J.A.; Anderson, C.J. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin α4β1-Expressing Immune Cells. Journal of immunology, 2017, 199(2), 806–815. doi: 10.4049/jimmunol.1700231
  4. Soni, K.S.; Lei, F.; Desale, S.S.; Marky, L.A.; Cohen, S.M.; Bronich, T.K. Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer. Journal of Controlled Release, 2017, 264, 276–287. doi: 10.1016/j.jconrel.2017.08.038
Cy® is a trademark of GE Healthcare.

Cyanine3 hydrazide

Cyanine3 hydrazide,Cy3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

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  • Cyanine3 hydrazide

Cyanine3 hydrazide

标签：Cyanine3,Cy3, Hydrazides, Microscopy
货号 规格 价格 货期
11070 1 mg 110.00$ in stock
21070 5 mg 210.00$ in stock
41070 25 mg 410.00$ in stock
51070 50 mg 695.00$ in stock
61070 100 mg 1190.00$ in stock

Cyanine3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.

This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.

Cyanine3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

该试剂可以标记各种含羰基分子，例如高碘酸氧化后的抗体和其他糖蛋白、经历氧化应激或脱氨基作用的蛋白质或还原糖。 Cyanine3 与许多荧光仪器兼容。

Cyanine3 absorbance and emission spectra

Cyanine3 hydrazide

Cyanine3 hydrazide相关产品

BDP TR hydrazide

BDP TR hydrazide for the labeling of carbonyl compounds with BDP TR, a borondipyrromethene matching ROX channel.

BDP TR 酰肼，用于用 BDP TR 标记羰基化合物，BDP TR 是一种匹配 ROX 通道的硼二吡咯亚甲基。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: red powder 红色粉末
Molecular weight: 543.57
Molecular formula: C30H40Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  2. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  3. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  4. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
Cy® is a trademark of GE Healthcare.

Cyanine3 maleimide

Cyanine3 maleimide,硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cy3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

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  • Reactive dyes
  • Dye maleimides
  • Cyanine3 maleimide

Cyanine3 maleimide

标签：Cyanine3, Cy3,Maleimides, Microscopy
货号 规格 价格 货期
11080 1 mg 110.00$ in stock
21080 5 mg 210.00$ in stock
41080 25 mg 410.00$ in stock
51080 50 mg 695.00$ in stock
61080 100 mg 1190.00$ in stock

Thiol mono-reactive Cyanine3 dye. This reagent can be used to attach Cyanine3 fluorophore (an analog of Cy3®) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides).

Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or other appropriate reductant prior to the labeling.

Labeling with Cyanine3 maleimide is selective, and efficient.

We recommend using water-soluble Sulfo-Cyanine3 maleimide for the labeling of antibodies and other sensitive proteins.

硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cyanine3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

标记前应使用 TCEP（三羧乙基膦）或其他合适的还原剂还原胱氨酸。

用 Cyanine3 马来酰亚胺标记具有选择性且有效。

我们建议使用水溶性 Sulfo-Cyanine3 马来酰亚胺标记抗体和其他敏感蛋白。

Cy3 absorbance and emission spectra

Cyanine3 maleimide

Cyanine3 maleimide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

Sulfo-Cyanine3 carboxylic acid

Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.

Sulfo-Cyanine3 不含未活化的单官能羧酸，水溶性染料。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

General properties

Appearance: red powder  红色粉末
Molecular weight: 666.56
Molecular formula: C36H43N4O3BF4
Solubility: well soluble in DMSO (0.50 M = 330 g/L), in DMF, dichloromethane, very poorly soluble in water (0.57 mM = 420 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  2. Budiardjo, S.J.; Deay, J.J.; Calkins, A.L.; Wimalasena, V.K.; Montezano, D.; Biteen, J.S.; Slusky, J.S.G. Colicin E1 Fragments Potentiate Antibiotics by Plugging TolC. bioRxiv, preprint. doi: 10.1101/692251
  3. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  4. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
Cy® is a trademark of GE Healthcare.

Cyanine3 alkyne,Cy3炔烃

Cyanine3 alkyne,Cy3 炔烃是一种可用于 Click Chemistry 反应的荧光团。使用该试剂，明亮且光稳定的 Cyanine3 报告基因（Cy3® 的类似物）可以连接到几乎任何带有叠氮基的分子上。这种炔烃是非水溶性的。 然而，当与有机共溶剂（DMSO 或 DMF）一起使用时，这种染料可以有效地附着在水溶性分子上，例如蛋白质或肽

  • Products
  • Reactive dyes
  • Dye alkynes
  • Cyanine3 alkyne

Cyanine3 alkyne

标签：Cyanine3, Cy3,Alkynes, Microscopy
货号 规格 价格 货期
A10B0 1 mg 110.00$ in stock
B10B0 5 mg 210.00$ in stock
C10B0 10 mg 310.00$ in stock
D10B0 25 mg 410.00$ in stock
E10B0 50 mg 695.00$ in stock
F10B0 100 mg 1190.00$ in stock

Cyanine3 alkyne is a fluorophore ready for the use in Click Chemistry reaction.

With this reagent, bright and photostable Cyanine3 reporter, an analog of Cy3®, can be attached to nearly any molecule bearing azide group.

This alkyne is non water-soluble. However, when used with organic co-solvent (DMSO or DMF), this dye can be efficiently attached to water-soluble molecules such as proteins, or peptides.

Cy3 炔烃是一种可用于 Click Chemistry 反应的荧光团。

使用该试剂，明亮且光稳定的 Cyanine3 报告基因（Cy3® 的类似物）可以连接到几乎任何带有叠氮基的分子上。

这种炔烃是非水溶性的。 然而，当与有机共溶剂（DMSO 或 DMF）一起使用时，这种染料可以有效地附着在水溶性分子上，例如蛋白质或肽。

Cyanine3 absorbance and emission spectra

Cyanine3 alkyne

Cyanine3 alkyne相关产品

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cy3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cy7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cyanine3羧酸。

General properties

Appearance: red powder 红色粉末
Molecular weight: 530.14
Molecular formula: C33H40ClN3O
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), , practically insoluble in water (50 mg/L = 80 uM)
Quality control: NMR 1H (95%), HPLC-MS
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  3. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  4. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
Cy2® is a trademark of GE Healthcare.