标签： Cy5.5

Cyanine5.5 phosphoramidite, 5′-terminal

Cyanine5.5 phosphoramidite, 5′-terminal,Cy5.5 是一种荧光团，在光谱的远红色范围内发射。 这种染料可用于多重 qPCR。 商用六通道 qPCR 仪器通常有一个用于 Cy5.5 的通道。

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  • Cyanine5.5 phosphoramidite, 5′-terminal

Cyanine5.5 phosphoramidite, 5′-terminal

标签：Cyanine5.5, Oligonucleotide synthesis, Phosphoramidite
货号 规格 价格 货期
2680-100mg 100 mg – 7 days
2680-250mg 250 mg 290.00$ 10 days
2680-1g 1 g 950.00$ in stock
2680-10g 10 g 6750.00$ 21 days
Cyanine5.5 is a fluorophore with the emission in far red range of the spectrum. This dye is useful for multiplex qPCR. Commercial six-channel qPCR instruments often have a channel for Cyanine5.5.

This phosphoramidite can be used for the synthesis of 5′-labeled oligonucleotides by direct labeling in oligonucleotide synthesizer.

The structure of phosphoramidite functional group that is attached to a secondary carbon atom provides extra stability against Arbuzov rearrangement. This helps maintaining coupling performance over a longer storage time in oligonucleotide synthesizer, compared to phosphoramidites derived of primary alcohols.

Cy5.5 是一种荧光团，在光谱的远红色范围内发射。 这种染料可用于多重 qPCR。 商用六通道 qPCR 仪器通常有一个用于 Cy5.5 的通道。
该亚磷酰胺可用于通过在寡核苷酸合成仪中直接标记来合成5′-标记的寡核苷酸。

与仲碳原子相连的亚磷酰胺官能团结构提供了额外的稳定性，可防止 Arbuzov 重排。 与衍生自伯醇的亚磷酰胺相比，这有助于在寡核苷酸合成仪中在较长的存储时间内保持偶联性能。

Absorption and emission spectra of Cyanine5.5

Cyanine5.5 phosphoramidite, 5'-terminal

Cyanine5.5 phosphoramidite, 5′-terminal相关产品

Phosphate CPG 1000 solid support

Phosphate modifier CPG for the solid phase synthesis of long (up to 120mer) oligonucleotides containing 3 prime phosphate modification.

磷酸盐修饰剂 CPG，用于固相合成含有 3 个磷酸基修饰的长（最多 120 聚体）寡核苷酸。

Cyanine5 phosphoramidite

Phosphoramidite derivative of Cyanine5 for the use in oligonucleotide synthesis.

Cy5 的亚磷酰胺衍生物，用于寡核苷酸合成。

FAM CPG 500, 6-isomer

Controlled pore glass for the synthesis of modified oligonucleotides containing 3′-fluorescein (FAM) modification.

用于合成含有 3′-荧光素 (FAM) 修饰的修饰寡核苷酸的可控孔玻璃。

General properties

Appearance: dark colored solid
Molecular weight: 916.61
Molecular formula: C55H71N5ClO3P
Quality control: NMR 1H, 31P, HPLC-MS (85%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 694
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: 6 min coupling time recommended
Deprotection conditions: recommended 48 h at +4°C or ultramild protective groups; 24 h at rt possible

Cyanine5.5 phosphoramidite, 5'-terminal

Cyanine5.5 DBCO

Cyanine5.5 DBCO,应变环炔烃和叠氮化物之间的应变促进炔烃叠氮化物环加成 (spAAc) 是一种有用的生物共轭方法，它消除了对经典 CuAAc Click 化学所需的铜催化剂的需求。

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  • Cyanine5.5 DBCO

Cyanine5.5 DBCO

标签：Cy5.5, Cycloalkyne
货号 规格 价格 货期
A70F0 1 mg 110.00$ in stock
B70F0 5 mg 210.00$ in stock
C70F0 10 mg 310.00$ in stock
D70F0 25 mg 410.00$ in stock
E70F0 50 mg 695.00$ in stock
F70F0 100 mg 1190.00$ in stock

Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

应变环炔烃和叠氮化物之间的应变促进炔烃叠氮化物环加成 (spAAc) 是一种有用的生物共轭方法，它消除了对经典 CuAAc Click 化学所需的铜催化剂的需求。

Cyanine5.5 DBCO 是一种含有 Cyanine5.5 荧光染料的环辛炔产品。 这种荧光团用于生物成像、生物分布研究和显微镜检查。

Cyanine5.5 DBCO 可用于将荧光团与各种叠氮化物结合。

Absorption and emission spectra of Cyanine5.5

Cyanine5.5 DBCO

Cyanine5.5 DBCO相关产品

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

Biotin alkyne

Biotin alkyne is a reactive affinity label which can be attached to biomolecules via Click Chemistry.

生物素炔烃是一种反应性亲和标记，可以通过点击化学连接到生物分子上。

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
CAS number: 2643308-61-4
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018

Cyanine5.5 tetrazine

Cyanine5.5 tetrazine,Cy5.5 是一种远红发射染料，适用于体内成像和需要低背景的应用。 这种 Cy5.5 衍生物含有四嗪部分，可与反式环辛烯、环丙烯和一些应变的环辛炔反应形成稳定的共轭物。

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  • Cyanine5.5 tetrazine

Cyanine5.5 tetrazine

标签：Cyanine5.5,Cy5.5, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
170E0 1 mg 110.00$ in stock
270E0 5 mg 290.00$ in stock
470E0 25 mg 690.00$ in stock
570E0 50 mg 1270.00$ in stock
670E0 100 mg 1990.00$ in stock

Cyanine5.5 is a far red emitting dye for in vivo imaging and applications requiring low background. This Cyanine5.5 derivative contains tetrazine moiety that reacts with trans-cyclooctenes, cyclopropenes, and some strained cyclooctynes with the formation of stable conjugates.

This labeling reaction is extremely fast, and can be used in vivo.

Cy5.5 是一种远红发射染料，适用于体内成像和需要低背景的应用。 这种 Cy5.5 衍生物含有四嗪部分，可与反式环辛烯、环丙烯和一些应变的环辛炔反应形成稳定的共轭物。

这种标记反应非常快，可以在体内使用。

Absorption and emission spectra of Cyanine5.5

Cyanine5.5 tetrazine

Cyanine5.5 tetrazine相关产品

BDP R6G tetrazine

BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to rhodamine 6G. It contains tetrazine fragment for iedDA ligation.

BDP R6G 四嗪是一种硼二吡咯亚甲基染料，其吸收和发射波长与罗丹明 6G 相似。 它包含用于 iedDA 连接的四嗪片段。

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

General properties

Appearance: dark blue solid  深蓝色固体
Mass spec M+ increment: 737.4
Molecular weight: 911.96
Molecular formula: C50H52N7F6OP
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Cyanine5.5 amine

Cyanine5.5 amine,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。Cyanine5.5（Cy5.5® 类似物）胺衍生物。 该染料含有一个游离胺基，可与多种官能团结合，包括 NHS 酯和环氧化物。

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  • Cyanine5.5 amine

Cyanine5.5 amine

标签：Cyanine5.5, Cy5.5, Amines
货号 规格 价格 货期
170C0 1 mg 110.00$ in stock
270C0 5 mg 210.00$ in stock
470C0 25 mg 410.00$ in stock
570C0 50 mg 695.00$ in stock
670C0 100 mg 1190.00$ in stock

Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.

Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.

Cyanine5.5（Cy5.5® 类似物）胺衍生物。 该染料含有一个游离胺基，可与多种官能团结合，包括 NHS 酯和环氧化物。

Cyanine5.5 是一种远红色染料，适用于活体成像和需要低荧光背景的应用。

Cy5.5 absorbance and emission spectra

Cyanine5.5 amine

Cyanine5.5 amine相关产品

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料，用于与叠氮化物的无铜点击化学缀合。

Cyanine7 carboxylic acid

Non-reactive, near-infrared fluorescent dye.

非反应性近红外荧光染料。

Cyanine7 alkyne

Cyanine7 alkyne is a near infrared (NIR) dye alkyne for Click chemistry.

Cy7 炔烃是一种用于点击化学的近红外 (NIR) 染料炔烃。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 753.88
CAS number: 2097714-44-6 (without anion), 2097714-45-7 (chloride)
Molecular formula: C46H58Cl2N4O
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Han, Z.; Chen, C.; Xu, X.; Bai, R.; Staedtke, V.; Huang, J.; Chan, K.W.Y.; Xu, J.; Kamson, D.O.; Wen, Z.; Knutsson, L.; Zijl, P.C.M.; Liu, G. Dynamic contrast-enhanced CEST MRI using a low molecular weight dextran. NMR in Biomedicine, in press. doi: 10.1002/nbm.4649
  2. Park, D.J.; Yun, W.S.; Kim, W.C.; Park, J.-E.; Lee, S.H.; Ha, S.; Choi, J.S.; Key, J.; Seo, Y.J. Improvement of stem cell-derived exosome release efficiency by surface modified nanoparticles. Research Square, preprint. doi: 10.21203/rs.3.rs-42143/v1
  3. Ahn, Y.J.; Yun, W.S.; Choi, J.S.; Kim, W.C.; Lee, S.H.; Park, D.J.; Park, J.E.; Key, J.; Seo, Y.J. Biodistribution of poly clustered superparamagnetic iron oxide nanoparticle labeled mesenchymal stem cells in aminoglycoside induced ototoxic mouse model. Biomedical Engineering Letters, 2021, 11(1), 39–53. doi: 10.1007/s13534-020-00181-6
  4. Zhang, Y.; Hughes, K.R.; Raghani, R.M.; Ma, J.; Orbach, S.; Jeruss, J.S.; Shea, L.D. Cargo-free immunomodulatory nanoparticles combined with anti-PD-1 antibody for treating metastatic breast cancer. Biomaterials, 2021, 269, 120666. doi: 10.1016/j.biomaterials.2021.120666
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid,Sulfo-Cyanine5.5（Cy5.5® 的类似物）是一种水溶性、发射远红光的荧光团。 由于四个磺基，该染料在中性pH下具有负电荷，并且具有非常高的亲水性。

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  • Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid

标签：Carboxylic acids, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17390 1 mg 110.00$ in stock
27390 5 mg 290.00$ 5 days
47390 25 mg 690.00$ in stock
57390 50 mg 1190.00$ in stock
67390 100 mg 1850.00$ in stock

Sulfo-Cyanine5.5 (analog of Cy5.5®) is a water-soluble, far red emitting fluorophore. Due to four sulfo-groups, the dye possesses negative charge in neutral pH, and very high hydrophilicity.

As a cyanine dye, sulfo-Cyanine5.5 shows very low dependence of the fluorescence on pH, and very high extinction coefficient.

Sulfo-Cyanine5.5（Cy5.5® 的类似物）是一种水溶性、发射远红光的荧光团。 由于四个磺基，该染料在中性pH下具有负电荷，并且具有非常高的亲水性。

作为一种花青染料，sulfo-Cyanine5.5 的荧光对 pH 的依赖性非常低，消光系数非常高。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cy5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cy7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

Sulfo-Cy7 羧酸是一种非反应性荧光染料，可用作 NIR（近红外）标记。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 1017.31
CAS number: 2183440-68-6 (inner salt)
Molecular formula: C40H39K3N2O14S4
Solubility: Well soluble in water, DMF, DMSO (0.39 M = 400 g/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  2. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  3. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  4. Wild, A.R.; Sinnen, B.L.; Dittmer, P.J.; Kennedy, M.J.; Sather, W.A.; Dell’Acqua, M.L. Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma. Cell Reports, 2019, 26, 3537–3550.e4. doi: 10.1016/j.celrep.2019.03.005
Cy® is a trademark of GE Healthcare.

Cyanine5.5 carboxylic acid

Cyanine5.5 carboxylic acid,

Cyanine5.5 carboxylic acid,Cy5.5 染料，游离酸形式，未活化。 对于大多数应用，染料可以被认为是非反应性的。 它可用作对照或参考样品，以及用于仪器校准。

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  • Cyanine5.5 carboxylic acid

Cyanine5.5 carboxylic acid

标签：Cyanine5.5,Cy5.5, Carboxylic acids
货号 规格 价格 货期
17090 1 mg 110.00$ in stock
27090 5 mg 210.00$ in stock
47090 25 mg 410.00$ in stock
57090 50 mg 695.00$ in stock
67090 100 mg 1190.00$ in stock

Cyanine5.5 dye, free acid form, unactivated. The dye can be considered non-reactive for most applications. It can be used as a control or reference sample, and for instrument calibration.

Pre-activated NHS ester for the labeling of amine groups is also available.

Cy5.5 染料，游离酸形式，未活化。 对于大多数应用，染料可以被认为是非反应性的。 它可用作对照或参考样品，以及用于仪器校准。

也可提供用于标记胺基的预活化 NHS 酯。

Cy5.5 absorbance and emission spectra

Cyanine5.5 carboxylic acid

Cyanine5.5 carboxylic acid相关产品

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

Sulfo-Cy7 羧酸是一种非反应性荧光染料，可用作 NIR（近红外）标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 619.23
CAS number: 1449661-34-0 (without anion), 1449612-07-0 (inner salt)
Molecular formula: C40H43ClN2O2
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​(5-​carboxypentyl)​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Francis, D.M. Manspeaker, M.P.; Archer, P.A.; Sestito, L.F.; Heiler, A.J.; Schudel, A.; Thomas, S.N. Drug-eluting immune checkpoint blockade antibody-nanoparticle conjugate enhances locoregional and systemic combination cancer immunotherapy through T lymphocyte targeting. Biomaterials, 2021, 279, 121184. doi: 10.1016/j.biomaterials.2021.121184
  2. Phung, C.D.; Le, T.G.; Nguyen, V.H.; Vu, T.T.; Nguyen, H.Q.; Kim, J.O.; Yong, C.S.; Nguyen, C.N. PEGylated-Paclitaxel and Dihydroartemisinin Nanoparticles for Simultaneously Delivering Paclitaxel and Dihydroartemisinin to Colorectal Cancer. Pharmaceutical Research, 2020, 37, 129. doi: 10.1007/s11095-020-02819-7
  3. Alfaifi, A.A.; Heyder, R.S.; Bielski, E.R.; Almuqbil, R.M.; Kavdia, M.; Gerk, P.M.; da Rocha, S.R.P. Megalin-targeting liposomes for placental drug delivery. Journal of Controlled Release, 2020, 324, 366–378. doi: 10.1016/j.jconrel.2020.05.033
  4. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
Cy® is a trademark of GE Healthcare.

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide,Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

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  • Reactive dyes
  • Dye hydrazides
  • Cyanine5.5 hydrazide

Cyanine5.5 hydrazide

标签：Cyanine5.5, Cy5.5,Hydrazides, Microscopy
货号 规格 价格 货期
17070 1 mg 110.00$ in stock
27070 5 mg 210.00$ in stock
47070 25 mg 410.00$ in stock
57070 50 mg 695.00$ in stock
67070 100 mg 1190.00$ in stock

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.

Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

生物分子中的羰基可以在氧化应激或蛋白质脱氨基后自发形成。或者，醛基可以通过糖蛋白（例如抗体）的糖残基的高碘酸氧化特异性地产生。抗体可被高碘酸钠氧化，并用Cyanine5.5酰肼标记，形成Cyanine5.5标记的抗体。由于抗体中的糖残基远离可变的表位结合位点，因此该方法特别适用于标记抗体。

Cy5.5 是一种近红外荧光团，是 Cy5.5® 的类似物。它特别适用于需要低荧光背景的应用。染料的吸收和发射波长表现出显着的组织穿透性，因此 Cy5.5 适用于体内近红外成像应用。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

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FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

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Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

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General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 669.73
Molecular formula: C40H46Cl2N4O
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide,Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

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  • Dye maleimides
  • Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide

标签：Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17380 1 mg 110.00$ in stock
27380 5 mg 290.00$ in stock
47380 25 mg 690.00$ in stock
57380 50 mg 1270.00$ in stock
67380 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案，应使用适当的还原剂（例如 TCEP）还原天然蛋白质的二硫键。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

BDP TMR maleimide

A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.

用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定，以及其他应用。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5&reg; channel.

用于 Cy5&reg; 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  2. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0

Cyanine5.5 maleimide

Cyanine5.5 maleimide,Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

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  • Cyanine5.5 maleimide

Cyanine5.5 maleimide

标签：Cyanine5.5, Cy5.5,Maleimides, Microscopy
货号 规格 价格 货期
17080 1 mg 110.00$ 5 days
27080 5 mg 210.00$ in stock
47080 25 mg 410.00$ in stock
57080 50 mg 695.00$ in stock
67080 100 mg 1190.00$ in stock

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

Cyanine5.5 的近红外发射使这种染料适用于生物成像应用。

Cyanine5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 maleimide

Cyanine5.5 maleimide相关产品

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cyanine5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

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Cyanine7.5 azide

Long-wavelength NIR fluorescent dye azide for Click chemistry.

用于点击化学的长波长 NIR 荧光染料叠氮化物。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 741.36
CAS number: 1593644-50-8
Molecular formula: C46H49ClN4O3
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508
  2. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  3. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  4. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383

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Cy® is a trademark of Cytiva.

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne,Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基，具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

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  • Dye alkynes
  • Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne

标签：Alkynes, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A73B0 1 mg 110.00$ in stock
B73B0 5 mg 290.00$ in stock
C73B0 10 mg 470.00$ in stock
D73B0 25 mg 690.00$ in stock
E73B0 50 mg 1270.00$ in stock
F73B0 100 mg 1990.00$ in stock
Sulfo-Cyanine5.5 is a far red emitting fluorophore. It contains four sulfo groups, which provide great hydrophilicity, and aqueous solubility. The reagent can be conjugated with a variety of azides by means of copper catalyzed Click chemistry reaction.
Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基，具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne相关产品

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR（近红外）染料叠氮化物，适用于铜催化和无铜点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 1054.36
Molecular formula: C43H42N3K3O13S4
IUPAC name: (E)-4-[(2E,4E)-5-{3,3-Dimethyl-5-[6-oxo-6-(2-propynylamino)hexyl]-10-(oxysulfonyl)-12-sulfo-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid tripotassium salt
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1

Cyanine5.5 alkyne

Cyanine5.5 alkyne,Cyanine5.5 alkyne,用于点击化学标记的远红/近红外染料炔烃。 Cyanine5.5 是 Cy5.5® 的类似物，Cy5.5® 是一种流行的荧光团，已广泛用于各种应用，包括完整的生物体成像。 该试剂可以在温和的铜催化点击化学条件下与叠氮基结合。

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  • Reactive dyes
  • Dye alkynes
  • Cyanine5.5 alkyne

Cyanine5.5 alkyne

标签：Cyanine5.5, Cy5.5,Alkynes, Microscopy
货号 规格 价格 货期
A70B0 1 mg 110.00$ in stock
B70B0 5 mg 210.00$ in stock
C70B0 10 mg 310.00$ in stock
D70B0 25 mg 410.00$ in stock
E70B0 50 mg 695.00$ in stock
F70B0 100 mg 1190.00$ in stock

Far red / near infrared dye alkyne for Click Chemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore which has been widely used for various applications including intact organism imaging. This reagent can be conjugated with azido groups under mild copper catalyzed Click Chemistry conditions.

This reagent is soluble in organic solvents, but mixtures of water with small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules with this far red/NIR dye.

用于点击化学标记的远红/近红外染料炔烃。 Cyanine5.5 是 Cy5.5® 的类似物，Cy5.5® 是一种流行的荧光团，已广泛用于各种应用，包括完整的生物体成像。 该试剂可以在温和的铜催化点击化学条件下与叠氮基结合。

该试剂可溶于有机溶剂，但水与少量 DMSO 的混合物可用于有效结合。 Cy5.5 炔烃也可用于用这种远红/NIR 染料标记小分子。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 alkyne

Cyanine5.5 alkyne相关产品

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.

用于 Click Chemistry 的反应性近红外 (NIR) 染料，含有末端炔基。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cy5.5 DBCO 是一种远红色的水溶性试剂，用于与叠氮化物的无铜反应。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 656.30
CAS number: 1628790-37-3
Molecular formula: C43H46ClN3O
Solubility: good in organic solvents (DMF, DMSO, acetonitrile, DCM, alcohols), practically insoluble in water (5.2 uM, 3.7 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  2. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  3. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  4. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物,Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团，在光谱的远红色区域具有发射，是 Cy5.5® 的类似物。 与其他花青染料一样，sulfo-Cyanine5.5 具有出色的摩尔消光系数，从而产生明亮的荧光。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide

标签：Azides, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A7330 1 mg 110.00$ 5 days
B7330 5 mg 290.00$ in stock
C7330 10 mg 470.00$ in stock
D7330 25 mg 690.00$ in stock
E7330 50 mg 1270.00$ in stock
F7330 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore which possesses emission in far red area of the spectrum, an analog of Cy5.5®. As other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient which gives rise to its bright fluorescence.

The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore – this minimizes non-specific binding.

The azide group of sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst, or with cycloalkynes in copper free strain promoted reaction.

Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团，在光谱的远红色区域具有发射，是 Cy5.5® 的类似物。 与其他花青染料一样，sulfo-Cyanine5.5 具有出色的摩尔消光系数，从而产生明亮的荧光。

该分子含有四个磺基，可为荧光团提供亲水性和负电荷 – 这最大限度地减少了非特异性结合。

磺基-Cyanine5.5 叠氮化物的叠氮基团可以在铜（I）催化剂存在下与末端炔烃共轭，或在无铜应变促进反应中与环炔烃共轭。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

BDP 581/591 azide

BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.

BDP 581/591 是一种相对疏水的硼二吡咯亚甲基荧光团，可用作 ROS 物种的探针或荧光偏振示踪剂。 这是一种用于点击化学的叠氮化物衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 984.2
Molecular weight: 1099.41
CAS number: 2382994-65-0
Molecular formula: C43H45K3N6O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  2. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
Cy® is a trademark of GE Healthcare.

Cy5.5 azide,Cy5.5 叠氮化物

Cy5.5 azide,Cy5.5 叠氮化物,这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine5.5 azide

Cyanine5.5 azide

标签：Cyanine5.5,Cy5.5, Azides, Microscopy
货号 规格 价格 货期
14030 100 uL, 10 mM/DMSO 110.00$ in stock
34030 500 uL, 10 mM/DMSO 210.00$ in stock
44030 1 mL, 10 mM/DMSO 410.00$ in stock
A4030 1 mg 110.00$ in stock
B4030 5 mg 210.00$ in stock
C4030 10 mg 310.00$ in stock
D4030 25 mg 410.00$ in stock
E4030 50 mg 695.00$ in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 azide

Cy5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cyanine7的胺活性NHS酯。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark blue powder / solution 深蓝色粉末/溶液
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  2. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  3. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  4. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
Cy® is a trademark of Cytiva.