标签： Cy5

Cy5 azide,Cy5 叠氮化物

Cy5 azide,Cy5 叠氮化物,用于 Click Chemistry 的 Cy5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

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  • Cyanine5 azide

Cyanine5 azide

标签：Cyanine5, Cy5,Azides, Microscopy
货号 规格 价格 货期
13030 100 uL, 10 mM/DMSO 110.00$ in stock
33030 500 uL, 10 mM/DMSO 210.00$ in stock
43030 1 mL, 10 mM/DMSO 410.00$ in stock
A3030 1 mg 110.00$ in stock
B3030 5 mg 210.00$ in stock
C3030 10 mg 310.00$ in stock
D3030 25 mg 410.00$ in stock
E3030 50 mg 695.00$ in stock
F3030 100 mg 1190.00$ in stock

Cyanine5 azide labeling reagent for Click Chemistry, available as 10 mM solution in DMSO, and in solid form.

This azide is soluble in organic solvents (e.g. DMSO, DMF), therefore the labeling reaction should be carried out with a small amount of an organic co-solvent. This azide can be used for the labeling of alkyne-modified biomolecules in mixtures of water with organic solvents. The solution in DMSO is ready for use in bioconjugation. A water-soluble sulfonated version of this reagent is also available.

Cyanine5 is an analog of Cy5®, one of the most commonly used fluorophores which is compatible with various instruments. Cyanine5 can also be used as a replacement for DyLight® 649.

用于 Click Chemistry 的 Cyanine5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。

这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

Cyanine5 是 Cy5® 的类似物，Cy5® 是最常用的荧光团之一，可与各种仪器兼容。 Cyanine5 也可用作 DyLight® 649 的替代品。

Cyanine5 absorbance and emission spectra

Cyanine5 azide

Cy5 azide,Cy5 叠氮化物相关产品

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

General properties

Appearance: dark blue powder / solution
Molecular weight: 601.22
CAS number: 1267539-32-1 (chloride)
Molecular formula: C35H45ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), very poorly soluble in water (0.63 mM, 110 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  2. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  3. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  4. von Döhren, J.; Kuhl, S. A simple method for long-term vital-staining of ciliated epidermal cells in aquatic larvae. Journal of Biological Methods, 2020, 7(2), e132. doi: 10.14440/jbm.2020.320
Cy® is a trademark of Cytiva.

Cy5 NHS ester minimal dye

Cy5 NHS ester minimal dye,用于蛋白质标记的 Cy5 最小染料，Cy5® 最小染料的类似物。该试剂经过专门量化，可用于 2D 蛋白质组学。 每个包装包含指定数量的 NHS 酯，数量变化在 10% 以内。

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  • Cyanine5 NHS ester minimal dye

Cyanine5 NHS ester minimal dye

标签：Cy5,NHS esters,Protein labeling
货号 规格 价格 货期
1C041 5 nmol 85.00$ in stock
2C041 10 nmol 140.00$ in stock
3C041 25 nmol 210.00$ in stock

Cyanine5 minimal dye for protein labeling, an analog of Cy5® minimal dye.

This reagent is specially quantified for the use in 2D proteomics. Each package contains specified amount of NHS ester with quantity variation within 10%.

用于蛋白质标记的 Cy5 最小染料，Cy5® 最小染料的类似物。

该试剂经过专门量化，可用于 2D 蛋白质组学。 每个包装包含指定数量的 NHS 酯，数量变化在 10% 以内。

Cyanine5 NHS ester minimal dye Cyanine5 NHS ester minimal dye Cyanine5 NHS ester minimal dye

Cy5 NHS ester minimal dye

相关产品

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.
Cy3 炔烃是一种用于 Click Chemistry 的荧光染料炔烃。

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.
Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.
氨基反应性 BDP FL，一种非常明亮且光稳定的荧光素通道染料。

General properties

Appearance: dark blue solid
Quality control: NMR 1H, HPLC-MS, functional testing
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
Emission maximum, nm: 662
CF260: 0.03
CF280: 0.04

相关文献：

  1. Lobov, A.A.; Babkina, I.Y.; Danilov, L.G.; Masharskiy, A.E.; Predeus, A.V.; Mikhailova, N.A.; Granovitch, A.I.; Maltseva, A.L. Species-Specific Proteins in the Oviducts of Snail Sibling Species: Proteotranscriptomic Study of Littorina fabalis and L. obtusata. Biology, 2021, 10(11), 1087. doi: 10.3390/biology10111087
  2. Nixon, B.; Anderson, A.L.; Bromfield, E.G.; Martin, J.H.; Cafe, S.L.; Skerrett-Byrne, D.A.; Dun, M.D.; Eamens, A.L.; De Iuliis, G.N.; Johnston, S.D. Post-testicular sperm maturation in the saltwater crocodile Crocodylus porosus: assessing the temporal acquisition of sperm motility. Reproduction, Fertility, and Development, 2021, 33(9), 530–539. doi: 10.1071/RD20204
  3. Shikov, A.E.; Malovichko, Y.V.; Lobov, A.A.; Belousova, M.E.; Nizhnikov, A.A.; Antonets, K.S. The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification of Bacillus thuringiensis. International Journal of Molecular Sciences, 2021, 22(5), 2244. doi: 10.3390/ijms22052244
  4. Serteyn, L.; Bosquee, E.; Delatour, A.; Rubio-Melendez, M.E.; Vega-Muñoz, K.V.; Ramirez, C.C.; Francis, F. Multi-approach comparative study of the two most prevalent genotypes of pea aphid Acyrthosiphon pisum (Hemiptera: Aphididae) in Chile. Entomological Science, 2021, 24(1), 55–67. doi: 10.1111/ens.12436

Cy® is a trademark of GE Healthcare.

Purchase of these products does not imply transfer of license to perform methods patented by Carnegie Mellon University covered by US patents 6,043,025, 6,127,134, 6,246,190, 7566,544, and 7,598,047 “Difference gel electrophoresis using matched multiple dyes” and family members in Australia, Canada, Europe and Japan.
购买这些产品并不意味着转让执行卡内基梅隆大学专利方法的许可，这些方法受美国专利 6,043,025、6,127,134、6,246,190、7566,544 和 7,598,047“使用匹配的多种染料的差异凝胶电泳”和澳大利亚、加拿大的家庭成员的保护 ，欧洲和日本。

Cyanine5 DBCO

Cyanine5 DBCO,一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

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  • Cyanine5 DBCO

Cyanine5 DBCO

标签：Cyanine5, Copper free Click chemistry, Cycloalkyne,Cy5
货号 规格 价格 货期
A30F0 1 mg 110.00$ in stock
B30F0 5 mg 210.00$ in stock
C30F0 10 mg 310.00$ in stock
D30F0 25 mg 410.00$ in stock
E30F0 50 mg 695.00$ in stock
F30F0 100 mg 1190.00$ in stock

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

在不存在铜催化剂的情况下，在应变促进的炔烃叠氮化物环加成 (spAAC) 中，应变的环炔烃，例如环辛炔，与叠氮化物反应非常迅速。 该反应非常快速、温和且具有生物相容性。

与其他环炔烃相比，DBCO 提供了最快的反应动力学，但仍具有良好的稳定性。

Absorption and emission spectra of Cyanine5

Cyanine5 DBCO

Cyanine5 DBCO相关产品

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cyanine5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

General properties

Appearance: dark blue solid 深蓝色固体
Mass spec M+ increment: 928.4
Molecular weight: 929.03
Molecular formula: C53H59N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine,水溶性氨基染料，用于酶促转氨标记，以及与亲电试剂的其他偶联。 Cy5 是一种流行的荧光团，可与不同的荧光测量仪器兼容。

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  • Reactive dyes
  • Amino dyes
  • Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine

标签：sulfo-Cyanine5, Amines,Cy5
货号 规格 价格 货期
133C0 1 mg 110.00$ in stock
233C0 5 mg 290.00$ in stock
433C0 25 mg 690.00$ in stock
533C0 50 mg 1270.00$ in stock
633C0 100 mg 1990.00$ in stock

Water soluble amino dye for enzymatic transamination labeling, and other coupling with electrophiles. Cyanine5 is a popular fluorophore which is compatible with different fluorescence measuring instruments.

Sulfo-Cyanine5 derivatives possess good water solubility.

水溶性氨基染料，用于酶促转氨标记，以及与亲电试剂的其他偶联。 Cyanine5 是一种流行的荧光团，可与不同的荧光测量仪器兼容。

Sulfo-Cyanine5 衍生物具有良好的水溶性。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.

Cy3 dibenzocyclooctyne (DBCO, or ADIBO) 是一种用于无铜点击化学的环炔烃染料衍生物。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.

用于点击化学的 TAMRA 荧光染料叠氮化物。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 740.98
CAS number: 2183440-44-8
Molecular formula: C38H52N4O7S2
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[5-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene)​-​1,​3-​pentadien-​1-​yl]​-​3,​3-​dimethyl-​5-​sulfo-​, inner salt
Solubility: moderate in water, well soluble in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Schotman, M.J.G.; Peters, M.M.C.; Krijger, G.C.; van Adrichem, I.; de Roos, R.; Bemelmans, J.L.M.; Pouderoijen, M.J.; Rutten, M.G.T.A.; Neef, K.; Chamuleau, S.A.J.; Dankers, P.Y.W. In Vivo Retention Quantification of Supramolecular Hydrogels Engineered for Cardiac Delivery. Advanced Healthcare Materials, 2021, 10(10), e2001987. doi: 10.1002/adhm.202001987
  2. Bos, I.; Timmerman, M.; Sprakel, J. FRET-Based Determination of the Exchange Dynamics of Complex Coacervate Core Micelles. Macromolecules, 2021, 54(1), 398–411. doi: 10.1021/acs.macromol.0c02387
  3. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Azizah, A.M.; Davis, T.P.; Tabor, R.F.; Kempe, K. Tuning Cellular Interactions of Carboxylic Acid Side Chain Containing Polyacrylates: The Role of Cyanine Dye Label and Side Chain Type. Biomacromolecules, 2020, 21(8), 3007–3016. doi: 10.1021/acs.biomac.0c00244
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Cyanine5 amine

Cyanine5 amine,Cy5 amine 是一种含有氨基的活性染料，是 Cy5® 胺的类似物。 该试剂可与多种活性酯和其他亲电试剂偶联。 例如，这种胺可以与 EDC 活化的羧基偶联。

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  • Reactive dyes
  • Amino dyes
  • Cyanine5 amine

Cyanine5 amine

标签：Cyanine5,Cy5, Amines
货号 规格 价格 货期
130C0 1 mg 110.00$ in stock
230C0 5 mg 210.00$ in stock
430C0 25 mg 410.00$ in stock
530C0 50 mg 695.00$ in stock
630C0 100 mg 1190.00$ in stock

Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.

This bright and photostable dye is suitable for many different methods of fluorescence detection. Colorful fluorophore can also be easily detected in small quantities (nanomols) by naked human eye.

Cyanine5 amine 是一种含有氨基的活性染料，是 Cy5® 胺的类似物。 该试剂可与多种活性酯和其他亲电试剂偶联。 例如，这种胺可以与 EDC 活化的羧基偶联。

这种明亮且光稳定的染料适用于许多不同的荧光检测方法。 肉眼也可以很容易地检测到少量（纳摩尔）的彩色荧光团。

Cyanine5 amine absorbance and emission spectra

Cyanine5 amine

Cyanine5 amine相关产品

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 653.77
CAS number: 1807529-70-9
Molecular formula: C38H54Cl2N4O
IUPAC name: 3H-​Indolium, 2-​[5-​[1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​3,​3-​trimethyl-
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Yin, X.; Ren, J.; Lan, W.; Chen, Y.; Ouyang, M.; Su, H.; Zhang, L.; Zhu, J.; Zhang, C. Microfluidics-assisted optimization of highly adhesive haemostatic hydrogel coating for arterial puncture. Bioactive Materials, in press. doi: 10.1016/j.bioactmat.2021.10.009
  2. Dao, N.V.; Ercole, F.; Li, Y.; Davis, T.P.; Kaminskas, L.M.; Sloan, E.K.; Quinn, J.F.; Whittaker, M.R. Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells. Journal of Materials Chemistry B, 2021, 9(37), 7805–7820. doi: 10.1039/D1TB00812A
  3. Kántor, I.; Aparaschivei, D.; Todea, A.; Biró, E.; Babos, G.; Szerényi, D.; Kakasi, B.; Péter, F:; Şişu, Eugen and Feczkó, T. Biocatalytic synthesis of poly[ε-caprolactone-co-(12-hydroxystearate)] copolymer for sorafenib nanoformulation useful in drug delivery. Catalysis Today, 2021, 366, 195–201. doi: 10.1016/j.cattod.2020.05.005
  4. Mizuno, H.L.; Anraku, Y.; Sakuma, I.; Akagi, Y. Design of a Photocleavable Drug Binding Platform for a Novel Remotely Controllable Drug Coated Balloon. Journal of Drug Delivery Science and Technology, 2021, 62, 102375. doi: 10.1016/j.jddst.2021.102375
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid,非活化磺基花青5羧酸，水溶性染料。 这种染料是高度亲水和水溶性的。 非磺化类似物可用。

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  • Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid

标签：sulfo-Cyanine5,sulfo-Cy5,Carboxylic acids
货号 规格 价格 货期
13390 1 mg 110.00$ in stock
23390 5 mg 210.00$ in stock
43390 25 mg 410.00$ in stock
53390 50 mg 695.00$ in stock
63390 100 mg 1190.00$ in stock

Non-activated sulfo-Cyanine5 carboxylic acid, water soluble dye. This dye is highly hydrophilic and water-soluble. Non-sulfonated analog is available.

The fluorophore is an equivalent of Cy5® carboxylic acid.

For labeling applications consider using pre-activated sulfo-Cy5 NHS ester

非活化磺基花青5羧酸，水溶性染料。 这种染料是高度亲水和水溶性的。 非磺化类似物可用。

荧光团相当于 Cy5® 羧酸。

对于标签应用，考虑使用预活化的磺基-Cy5 NHS 酯

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

Cyanine7.5 carboxylic acid

Cyanine7.5 – unactivated NIR cyanine dye carboxylic acid.

Cy7.5 – 未活化的近红外花青染料羧酸。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 680,87
CAS number: 1144107-82-3 (potassium salt), 1121756-16-8 (inner salt), 2098639-31-5 (sodium salt)
Molecular formula: C32H37N2KO8S2
Solubility: Well soluble in water, DMF, DMSO (0.35 M = 240 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Sun, X.; Du, J.D.; Hawley, A.; Tan, A.; Boyd, B.J. Magnetically-stimulated transformations in the nanostructure of PEGylated phytantriol-based nanoparticles for on-demand drug release. Colloids and Surfaces B: Biointerfaces, 2021, 207, 112005. doi: 10.1016/j.colsurfb.2021.112005
  2. Novoselova, M.V.; Abakumova, T.O.; Khlebtsov, B.N.; Zatsepin, T.S.; Lazareva, E.N.; Tuchin, V.V.; Zharov, V.P.; Gorin, D.A.; Galanzha, E.I. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics, 2020, 20, 100186. doi: 10.1016/j.pacs.2020.100186
  3. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  4. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
Cy® is a trademark of GE Healthcare.

Cyanine5 hydrazide

Cyanine5 hydrazide,Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

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  • Cyanine5 hydrazide

Cyanine5 hydrazide

标签: Cyanine5, Cy5,Hydrazides, Microscopy
货号 规格 价格 货期
13070 1 mg 110.00$ in stock
23070 5 mg 210.00$ in stock
43070 25 mg 410.00$ in stock
53070 50 mg 695.00$ in stock
63070 100 mg 1190.00$ in stock

Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.

This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.

Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, DyLight 649 dyes.

Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。

这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

Cyanine5 酰肼替代羰基反应性 Cy5®、DyLight 649 染料。

Cy5 absorbance and emission spectra

Cyanine5 hydrazide

Cyanine5 hydrazide相关产品

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.

荧光素 (FAM) 的环辛炔衍生物，用于与叠氮化物的无铜点击化学反应。 含有纯6-异构体的荧光素。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cyanine5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 569.61
CAS number: 1427705-31-4
Molecular formula: C32H42Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  2. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  4. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
Cy® is a trademark of Cytiva.

Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide,Boc 保护的 Cy5 酰肼活性染料，用于标记醛和酮。Cyanine5 Boc-hydrazide,Cy5

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  • Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide

货号 规格 价格 货期
130A0 1 mg 110.00$ in stock
230A0 5 mg 210.00$ 5 days
430A0 25 mg 410.00$ 5 days
530A0 50 mg 695.00$ in stock
630A0 100 mg 1190.00$ 5 days

Boc-protected Cyanine5 hydrazide reactive dye for the labeling of aldehydes and ketones.

Boc- (tert-butoxycarbonyl) protective group can be removed with trifluoroacetic acid, or other strong acid. Reactive hydrazide is formed, which can then couple with various carbonyl groups yielding Cyanine5-labeled molecules.

Boc 保护的 Cy5 酰肼活性染料，用于标记醛和酮。

Boc-（叔丁氧羰基）保护基可以用三氟乙酸或其他强酸去除。 形成反应性酰肼，然后可以与各种羰基偶联，产生花青 5 标记的分子。

Cyanine5 absorbance and emission spectra

Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide相关产品

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.

用于 NHS 酯标记的干燥高纯度无胺溶剂。

Cyanine3 NHS ester minimal dye

Cyanine3 minimal dye for protein labeling.

用于蛋白质标记的 Cyanine3 最小染料。

Cyanine5 NHS ester minimal dye

Cy5 NHS ester minimal dye for protein labeling.

Cy5 NHS 酯最小染料用于蛋白质标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 633.26
Molecular formula: C37H49ClN4O3
Solubility: good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide,水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

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  • Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide

标签：sulfo-Cyanine5, Cy5,Maleimides, Microscopy
货号 规格 价格 货期
13380 1 mg 110.00$ in stock
23380 5 mg 290.00$ in stock
43380 25 mg 690.00$ in stock
53380 50 mg 1270.00$ in stock
63380 100 mg 1990.00$ in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

也可使用不含磺基的类似物 Cyanine5 马来酰亚胺。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide相关产品

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

ROX NHS ester, 6- isomer

Pure isomer 6-ROX NHS ester for amine labeling.

用于胺标记的纯异构体 6-ROX NHS 酯。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark blue powder  深蓝色粉末
Molecular weight: 803.00
CAS number: 2242791-82-6
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
Cy® is a trademark of GE Healthcare.

Cyanine5 maleimide

Cyanine5 maleimide,Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

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  • Reactive dyes
  • Dye maleimides
  • Cyanine5 maleimide

Cyanine5 maleimide

标签：Cyanine5,Cy5, Maleimides, Microscopy
货号 规格 价格 货期
13080 1 mg 110.00$ in stock
23080 5 mg 210.00$ in stock
43080 25 mg 410.00$ in stock
53080 50 mg 695.00$ in stock
63080 100 mg 1190.00$ in stock

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates.

Cyanine5 is an analog of Cy5®, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers.

For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.

Cy5 马来酰亚胺是一种单反应性染料，可选择性地与硫醇基团（例如，与肽和蛋白质中的半胱氨酸）偶联，形成标记的偶联物。

Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

对于抗体和敏感蛋白的标记，我们建议使用水溶性磺基-Cyanine5 马来酰亚胺。

Cy5 excitation and emission spectra

Cyanine5 maleimide

Cyanine5 maleimide相关产品

FAM hydrazide, 5-isomer

FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.

FAM 酰肼是一种羰基反应性荧光素衍生物。 纯5-异构体。 可以用羰基标记氧化的蛋白质、糖类和许多小分子。

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Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 605.8
CAS number: 1437872-46-2 (without anion)
Molecular formula: C38H45N4O3
IUPAC name: 3H-​Indolium, 2-​[5-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​3,​3-​trimethyl-
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Pishesha, N.; Harmand, T.; Smeding, L.; Ma, W.; Ludwig, L.; Janssen, R.; Islam, A.; Xie, Y.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H.; Ploegh, H. Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance. Research Square, preprint. doi: 10.21203/rs.3.rs-192181/v1
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  4. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne,用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

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  • Reactive dyes
  • Dye alkynes
  • Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

标签：sulfo-Cyanine5, Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A33B0 1 mg 110.00$ in stock
B33B0 5 mg 290.00$ in stock
C33B0 10 mg 470.00$ in stock
D33B0 25 mg 690.00$ in stock
E33B0 50 mg 1270.00$ in stock
F33B0 100 mg 1990.00$ in stock

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

该试剂推荐用于与蛋白质、纳米颗粒和亲水性很重要的其他应用结合。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的Cy5 胺官能化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团，但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Cyanine5 alkyne,Cy5炔烃

Cyanine5 alkyne,Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。

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  • Reactive dyes
  • Dye alkynes
  • Cyanine5 alkyne

Cyanine5 alkyne

标签：Cyanine5,Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A30B0 1 mg 110.00$ in stock
B30B0 5 mg 210.00$ in stock
C30B0 10 mg 310.00$ in stock
D30B0 25 mg 410.00$ in stock
E30B0 50 mg 695.00$ in stock
F30B0 100 mg 1190.00$ in stock

Cyanine5 alkyne for Click Chemistry, an analog of Cy5® alkyne. With this product, deeply colored, and photostable Cyanine5 fluorophore can be attached to various molecules via Click Chemistry reaction with azides.

This alkyne is non-water soluble, but it can be dissolved in DMF or DMSO prior to reaction, and added to aqueous reaction mixture. With our labeling protocol, the labeling reaction is very efficient, and high-yielding.

Various substrates bearing azides can be used for the labeling, including azido-labeled biomolecules, polymers, and solid surfaces.

Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。

这种炔烃不溶于水，但它可以在反应前溶解在 DMF 或 DMSO 中，然后加入到含水反应混合物中。 使用我们的标记方案，标记反应非常有效且产量高。

带有叠氮化物的各种基材可用于标记，包括叠氮标记的生物分子、聚合物和固体表面。

Cyanine5 absorbance and emission spectra

Cyanine5 alkyne

Cyanine5 alkyne

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 556.18
CAS number: 1223357-57-0
Molecular formula: C35H42ClN3O
Solubility: good in dichloromethane, DMF, DMSO, alcohols, very poorly soluble in water (200 mg/L = 0.4 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Liu, M.; Apriceno, A.; Sipin, M.; Scarpa, E.; Rodriguez-Arco, L.; Poma, A.; Marchello, G.; Battaglia, G.; Angioletti-Uberti, S. Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions. Nature Communications, 2020, 11, 4836. doi: 10.1038/s41467-020-18603-5
  2. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  3. Monteiro, P.F.; Gulfam, M.; Monteiro, C.J.; Travanut, A.; Abelha, T.F.; Pearce, A.K.; Jerôme, C.; Grabowska, A.M.; Clarke, P.A.; Collins, H.M.; Heery, D.M.; Gershkovich, P.; Alexander, C. Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. Journal of Controlled Release, 2020, 323, 549–564. doi: 10.1016/j.jconrel.2020.04.049
  4. Zivanovic, J.; Kouroussis, E.; Kohl, J.B.; Adhikari, B.; Bursac, B.; Schott-Roux, S.; Petrovic, D.; Miljkovic, J.L.; Thomas-Lopez, D.; Jung, Y.; Miler, M.; Mitchell, S.; Milosevic, V.; Gomes, J.E.; Benhar, M.; Gonzales-Zorn, B.; Ivanovic-Burmazovic, I.; Torregrossa, R:; Mitchell, J.R.; Whiteman, M.; Schwarz, G.; Snyder, S.H.; Paul, B.D.; Carroll, K.S.; Filipovic, M.R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 2019, 30(6), 1152–1170.e13. doi: 10.1016/j.cmet.2019.10.007
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 azide,Cy5 叠氮化物

Sulfo-Cyanine5 azide,Cy5 叠氮化物,用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide

标签：sulfo-Cyanine5,Cy5, Azides, Microscopy
货号 规格 价格 货期
A3330 1 mg 110.00$ in stock
B3330 5 mg 290.00$ in stock
C3330 10 mg 470.00$ in stock
D3330 25 mg 690.00$ in stock
E3330 50 mg 1270.00$ in stock
F3330 100 mg 1990.00$ in stock

Water-soluble Cyanine5 dye azide for Click chemistry. Bright and photostable dye with red fluorescence. The reagent has high water solubility. Due to high solubility and hydrophilicity, the dye can be used for labeling biomolecules in native, purely aqueous conditions.

This reagent, as opposed to competing products, is supplied as an alkaline metal salt and not triethylammonium salt. Therefore, it is a powder which is easy to handle and dispense.

Sulfo-Cyanine5 is an analog of Cy5®, a very popular fluorophore, therefore this reagent is compatible to a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes.

用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

与竞争产品不同，该试剂以碱金属盐而非三乙基铵盐的形式提供。 因此，它是一种易于处理和分配的粉末。

Sulfo-Cyanine5 是 Cy5® 的类似物，Cy5® 是一种非常流行的荧光团，因此该试剂与各种标准荧光仪器兼容，例如成像仪、读板机和显微镜。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide,Cy5 叠氮化物相关产品

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

General properties

Appearance: dark blue crystals 深蓝色晶体
Molecular weight: 762.98
Molecular formula: C35H43N6KO7S2
Solubility: very high in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution. doi: 10.1159/000519068
  2. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. bioRxiv, preprint. doi: 10.1101/2021.02.12.430891
  3. Toyonaga, T.; Keith, B.P.; Barrow, J.B.; Schaner, M.S.; Wolber, E.A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N.L.; Chaumont, N.; Sadiq, T.S.; Koruda, M.j.; Rahbar, R.; Furey, T.S.; Sethupathy, P.; Sheikh, S.Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohn’s disease. bioRxiv, preprint. doi: 10.1101/2020.02.21.960070
  4. Hinman, S.; Wang, Y.; Allbritton, N. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. ChemRxiv, preprint. doi: 10.26434/chemrxiv.9759605.v1
Cy® is a trademark of GE Healthcare.