标签： Copper free Click chemistry

DBCO NHS ester

DBCO NHS ester,二苯并环辛炔 (ADIBO, DBCO) 是对应变促进炔烃叠氮化物环加成 (spAAC) 反应性最强的环炔烃之一 – 一种无铜点击化学反应。

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  • DBCO NHS ester

DBCO NHS ester

标签：NHS esters, Alkynes, Copper free Click chemistry, Cycloalkyne, Protein labeling, Cross linking reagents
货号 规格 价格 货期
34720 10 mg 60.00$ in stock
44720 25 mg 95.00$ in stock
54720 50 mg 145.00$ in stock
64720 100 mg 210.00$ in stock
94720 1 g 1190.00$ in stock
K4720 5 g 3570.00$ in stock
N4720 25 g please inquire 21 days

Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain promoted alkyne azide cycloaddition (spAAC) – a copper free Click chemistry reaction.

This is an amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

DBCO reacts instantly with azides. The rate of the reaction is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines – this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines.

二苯并环辛炔 (ADIBO, DBCO) 是对应变促进炔烃叠氮化物环加成 (spAAC) 反应性最强的环炔烃之一 – 一种无铜点击化学反应。

这是一种胺反应性 NHS 酯，可将反应性部分轻松连接到几乎任何伯胺或仲胺基团，例如蛋白质、肽或小分子胺的基团。

DBCO 立即与叠氮化物发生反应。 该反应的速率远高于铜催化的反应，以及与许多其他环辛炔的反应。 与其他一些环辛炔不同，DBCO 不与四嗪反应 – 这允许叠氮化物与 DBCO 以及反式环辛烯与四嗪的正交共轭。

DBCO NHS ester相关产品

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

General properties

Appearance: off white solid
Mass spec M+ increment: 315.1
Molecular weight: 430.45
CAS number: 1384870-47-6
Molecular formula: C25H22N2O5
IUPAC name: 6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Adams, M.R.; Moody, C.T.; Sollinger, J.L.; Brudno, Y. Extracellular Matrix-Anchored Click Motifs for Specific Tissue Targeting. Molecular Pharmaceutics, 2020, 17(2), 392–403. doi: 10.1021/acs.molpharmaceut.9b00589
  2. Alshanski, I.; Blaszkiewicz, J.; Mervinetsky, E.; Rademann, J.; Yitzchaik, S.; Hurevich, M. Sulfation Patterns of Saccharides and Heavy Metal Ions Binding. Chemistry, 2019, 25(52), 12083–12090. doi: 10.1002/chem.201901538
  3. Andersen, V.L.; Vinther, M.; Kumar, R.; Ries, A.; Wengel, J.; Nielsen, J.S.; Kjems, J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics, 2019, 9(9), 2662–2677. doi: 10.7150/thno.32060

AmdU (5-azidomethyl-2′-deoxyuridine)

AmdU (5-azidomethyl-2′-deoxyuridine),叠氮甲基-dU (AmdU) 是一种含有叠氮基的核苷。 核苷的结构类似于胸苷，它通过细胞聚合酶掺入新生DNA中，类似于EdU。

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  • AmdU (5-azidomethyl-2′-deoxyuridine)

AmdU (5-azidomethyl-2′-deoxyuridine)

标签：Azides, Copper free Click chemistry
货号 规格 价格 货期
B1540 5 mg 120.00$ in stock
D1540 25 mg 255.00$ in stock
F1540 100 mg 890.00$ in stock</td

Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU.

Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.

叠氮甲基-dU (AmdU) 是一种含有叠氮基的核苷。 核苷的结构类似于胸苷，它通过细胞聚合酶掺入新生DNA中，类似于EdU。

与需要在铜催化剂存在下用叠氮化物进一步改性的 EdU 不同，AmdU 也可以在没有铜催化剂的情况下使用 spAAC Click Chemistry 与应变的环炔烃（例如环辛炔）发生反应。 这使得在良性、无铜条件下检测新生 DNA 成为可能。

AmdU (5-azidomethyl-2′-deoxyuridine)相关产品

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cy3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

General properties

Appearance: white / off white solid 白色/米白色固体
Molecular weight: 283.24
Molecular formula: C10H13N5O5
IUPAC name: 5-Azidomethyl-2′-deoxyuridine
Solubility: good in water, alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO,Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cy5.5 衍生物，即 DBCO（或 ADIBO）衍生物，含有环炔烃，用于无铜共轭这种荧光团与各种有机叠氮化物。

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  • sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO

标签：Copper free Click chemistry, Cycloalkyne, sulfo-Cy5.5
货号 规格 价格 货期
173F0 1 mg 110.00$ in stock
273F0 5 mg 290.00$ in stock
473F0 25 mg 690.00$ in stock
573F0 50 mg 1270.00$ in stock
673F0 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a dye with far-red emission approaching NIR range. It has found application in non-invasive live-organism imaging. This particular derivative of sulfo-Cyanine5.5, the DBCO (or ADIBO) derivative, contains cycloalkyne for copper-free conjugation of this fluorophore with various organic azides.

The reaction between DBCO and azides is blazingly fast, orders of magnitude exceeding the rate of copper-catalyzed reaction between azides and terminal alkynes. It is also catalyst-free.

This reagent can be used to conjugate sulfo-Cyanine5.5 dye to a variety of azide-labeled molecules.

Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cyanine5.5 衍生物，即 DBCO（或 ADIBO）衍生物，含有环炔烃，用于无铜共轭这种荧光团与各种有机叠氮化物。

DBCO 和叠氮化物之间的反应非常快，数量级超过了铜催化的叠氮化物和末端炔烃之间的反应速率。 它也不含催化剂。

该试剂可用于将磺基-Cyanine5.5 染料与多种叠氮化物标记的分子结合。

Absorption and emission spectra of sulfo-Cyanine5.5

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素（一种众所周知的亲和探针）进行点击化学标记的试剂。

General properties

Appearance: dark blue solid
Molecular weight: 1317.69
Molecular formula: C61H59N4K3O14S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO,Copper free Click chemistry reaction between strained cycloalkynes (cyclooctynes), and azides, is a very fast and robust reaction. It can be used for a fast labeling with fluorescent dyes. This reagent is a derivative of water soluble sulfo-Cyanine5 dye which emits in red channel. It is useful for the labeling of biomolecules in aqueous media.

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  • sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO

标签：sulfo-Cy5, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
133F0 1 mg 110.00$ in stock
233F0 5 mg 290.00$ in stock
433F0 25 mg 690.00$ in stock
533F0 50 mg 1270.00$ in stock
633F0 100 mg 1990.00$ in stock

Copper free Click chemistry reaction between strained cycloalkynes (cyclooctynes), and azides, is a very fast and robust reaction. It can be used for a fast labeling with fluorescent dyes. This reagent is a derivative of water soluble sulfo-Cyanine5 dye which emits in red channel. It is useful for the labeling of biomolecules in aqueous media.

紧张的环炔烃（环辛炔）和叠氮化物之间的无铜点击化学反应是一种非常快速且稳定的反应。 它可用于荧光染料的快速标记。 该试剂是水溶性磺基-Cyanine5染料的衍生物，在红色通道中发射。 它可用于标记水性介质中的生物分子。

Absorption and emission spectra of sulfo-Cyanine5

sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO相关产品

TMRE, Tetramethylrhodamine ethyl ester, perchlorate

Orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.

橙红色荧光染料，用于染色活性线粒体和定量活细胞中的线粒体膜电位。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cy5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

General properties

Appearance: dark colored solid
Molecular weight: 981.27
Molecular formula: C53H57N4KO8S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关产品

  1. Mamot, A.; Sikorski, P.J.; Siekierska, A.; de Witte, P.; Kowalska, J.; Jemielity, J. Ethylenediamine derivatives efficiently react with oxidized RNA 3′ ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation. Nucleic Acids Research, 2022, 50(1), e3. doi: 10.1093/nar/gkab867
  2. Lim, S.; Kim, W.; Song, S.; Shim, M.K.; Yoon, H.Y.; Kim, B.-S.; Kwon, I.C.; Kim, K. Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells. Bioconjugate Chemistry, 2021, 32(1), 199–214. doi: 10.1021/acs.bioconjchem.0c00640
  3. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5

sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。Sulfo-Cyanine3 DBCO 是一种具有环炔基团的水溶性荧光染料，用于无铜点击化学。

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  • sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO

标签：Copper free Click chemistry, Cycloalkyne, sulfo-Cyanine3
货号 规格 价格 货期
113F0 1 mg 110.00$ in stock
213F0 5 mg 290.00$ in stock
413F0 25 mg 690.00$ in stock
513F0 50 mg 1270.00$ in stock
613F0 100 mg 1990.00$ in stock

Sulfo-Cyanine3 DBCO is a water soluble fluorescent dye with cycloalkyne group for copper free Click chemistry.

DBCO (dibenzocyclooctyne) is a cyclooctyne with very high reactivity towards azides, still possessing good stability.

Sulfo-Cyanine3 DBCO 是一种具有环炔基团的水溶性荧光染料，用于无铜点击化学。

DBCO（二苯并环辛炔）是一种环辛炔，对叠氮化物具有非常高的反应性，但仍具有良好的稳定性。

Absorption and emission spectra of sulfo-Cyanine3

sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO相关产品

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cy3 染料叠氮化物。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5&reg; channel.

用于 Cy5&reg; 的硫醇活性水溶性花青染料 渠道。

Sulfo-Cyanine5.5 NHS ester

Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

NHS 酯形式的水溶性磺化远红色磺基-Cy5.5 染料。

General properties

Appearance: red solid 红色固体
Mass spec M+ increment: 916.4
Molecular weight: 955.23
Molecular formula: C51H55N4KO8S2
Solubility: soluble in water (0.11 M = 11 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关产品

  1. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  2. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5

ROX DBCO, 5-isomer

ROX DBCO, 5-isomer,ROX DBCO 是明亮的罗丹明染料罗丹明 X 和 DBCO（二苯并环辛炔）的共轭物，DBCO（二苯并环辛炔）是一种反应性基团，包含用于与叠氮化物共轭的应变炔键。

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  • ROX DBCO, 5-isomer

ROX DBCO, 5-isomer

标签：ROX (Rhodamine X, Rhodamine 101), Copper free Click chemistry, Cycloalkyne
112F0 1 mg 110.00$ in stock
212F0 5 mg 290.00$ in stock
412F0 25 mg 690.00$ in stock
512F0 50 mg 1270.00$ in stock
612F0 100 mg 1990.00$ in stock

ROX DBCO is a conjugate of bright rhodamine dye rhodamine X, and DBCO (dibenzocyclooctyne) – a reactive group that contains a strained alkyne bond for the conjugation with azides.

This reagent is useful for the labeling of various azides with ROX dye.

This derivative contains pure 5-isomer of ROX.

ROX DBCO 是明亮的罗丹明染料罗丹明 X 和 DBCO（二苯并环辛炔）的共轭物，DBCO（二苯并环辛炔）是一种反应性基团，包含用于与叠氮化物共轭的应变炔键。

该试剂可用于用 ROX 染料标记各种叠氮化物。

该衍生物含有纯的 ROX 5-异构体。

Absorption and emission spectra of ROX

ROX DBCO, 5-isomer

ROX DBCO, 5-isomer相关产品

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cyanine7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

ROX azide, 5- isomer

ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.

ROX（又名罗丹明 X 或罗丹明 101）叠氮化物，用于通过 Click Chemistry 进行生物分子标记。

BDP 630/650 tetrazine

BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.

BDP 630/650 是用于 Cyanine5 通道的硼二吡咯亚甲基染料。 这是一种用于与应变环烯烃偶联的四嗪衍生物。

General properties

Appearance: red solid 红色固体
Mass spec M+ increment: 834.4
Molecular weight: 835.00
Molecular formula: C54H50N4O5
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.00

FAM DBCO, 6-isomer

FAM DBCO, 6-isomer,荧光素 (FAM) 是最古老但众所周知的荧光染料之一。 FAM 的这种衍生物含有环辛炔基团（二苯并环辛炔，缩写为 DBCO 或 ADIBO），用于通过无铜、应变促进的叠氮化物炔烃环加成 (spAAc) 与叠氮化物结合。

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  • FAM DBCO, 6-isomer

FAM DBCO, 6-isomer

标签：FAM (Fluorescein), Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
151F0 1 mg 110.00$ in stock
251F0 5 mg 210.00$ in stock
451F0 25 mg 160.00$ in stock
551F0 50 mg 270.00$ in stock
651F0 100 mg 420.00$ in stock
Fluorescein (FAM) is one of the oldest yet well known fluorescent dyes. This derivative of FAM contains cyclooctyne group (dibenzocyclooctyne, abbreviated as DBCO or ADIBO) for the conjugation with azides via copper-free, strain-promoted azide alkyne cycloaddition (spAAc).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Azides react with DBCO spontaneously upon simple mixing. The reaction does not require any catalysts, and it is very efficient.

Fluorescein can be detected using a variety of different instruments.

荧光素 (FAM) 是最古老但众所周知的荧光染料之一。 FAM 的这种衍生物含有环辛炔基团（二苯并环辛炔，缩写为 DBCO 或 ADIBO），用于通过无铜、应变促进的叠氮化物炔烃环加成 (spAAc) 与叠氮化物结合。

FAM DBCO 可用于标记蛋白质、肽、核酸和其他含有叠氮基的分子。 叠氮化物在简单混合后会与 DBCO 自发反应。 该反应不需要任何催化剂，而且非常有效。

可以使用多种不同的仪器检测荧光素。

FAM DBCO, 6-isomer相关产品

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料，用于与叠氮化物的无铜点击化学缀合。

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物，用于 FAM（荧光素）488 nm 通道的硼二吡咯亚甲基染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

General properties

Appearance: orange solid 橙色固体
Molecular weight: 676.71
Molecular formula: C42H32N2O7
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

Cyanine7 DBCO

Cyanine7 DBCO,Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

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  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine7 DBCO

Cyanine7 DBCO

标签：Cyanine7, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A50F0 1 mg 110.00$ in stock
B50F0 5 mg 210.00$ in stock
C50F0 10 mg 310.00$ in stock
D50F0 25 mg 410.00$ in stock
E50F0 50 mg 695.00$ in stock
F50F0 100 mg 1190.00$ in stock

Cyanine7 DBCO is a NIR fluorescent dye with cycloalkyne moiety for the conjugation with azides by means of copper-free, strain promoted alkyne azide cycloaddition (spAAC).

Azodibenzocyclooctyne (DBCO or ADIBO) fragment is a stable but active cycloalkyne that reacts very rapidly with azides.

Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

偶氮二苯并环辛炔（DBCO 或 ADIBO）片段是一种稳定但具有活性的环炔烃，可与叠氮化物快速反应。

Absorption and emission spectra of Cyanine7 fluorophore

Cyanine7 DBCO

Cyanine7 DBCO相关产品

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cy5 荧光团的远红通道。

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

EdU (5-ethynyl-2′-deoxyuridine)

EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.

EdU 是一种核苷，可通过细胞酶掺入复制的 DNA 中。 之后，细胞中所含的 DNA 可以通过与荧光染料叠氮化物的 Click 化学反应进行显色，以揭示细胞增殖情况。

General properties

Appearance: dark green solid 深绿色固体
Mass spec M+ increment: 849.5
Molecular weight: 885.62
CAS number: 2692677-77-1
Molecular formula: C58H65N4ClO2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  2. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574

Cyanine5 DBCO

Cyanine5 DBCO,一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

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  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine5 DBCO

Cyanine5 DBCO

标签：Cyanine5, Copper free Click chemistry, Cycloalkyne,Cy5
货号 规格 价格 货期
A30F0 1 mg 110.00$ in stock
B30F0 5 mg 210.00$ in stock
C30F0 10 mg 310.00$ in stock
D30F0 25 mg 410.00$ in stock
E30F0 50 mg 695.00$ in stock
F30F0 100 mg 1190.00$ in stock

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

在不存在铜催化剂的情况下，在应变促进的炔烃叠氮化物环加成 (spAAC) 中，应变的环炔烃，例如环辛炔，与叠氮化物反应非常迅速。 该反应非常快速、温和且具有生物相容性。

与其他环炔烃相比，DBCO 提供了最快的反应动力学，但仍具有良好的稳定性。

Absorption and emission spectra of Cyanine5

Cyanine5 DBCO

Cyanine5 DBCO相关产品

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cyanine5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

General properties

Appearance: dark blue solid 深蓝色固体
Mass spec M+ increment: 928.4
Molecular weight: 929.03
Molecular formula: C53H59N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
Cy® is a trademark of GE Healthcare.

Cyanine3 DBCO

Cyanine3 DBCO,偶氮二苯并环辛炔（DBCO 或 ADIBO）是一种稳定但非常活泼的环炔烃，适用于无铜点击化学。

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  • Cycloalkyne dyes
  • Cyanine3 DBCO

Cyanine3 DBCO

标签：Cy3, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A10F0 1 mg 110.00$ in stock
B10F0 5 mg 210.00$ in stock
C10F0 10 mg 310.00$ in stock
D10F0 25 mg 410.00$ 5 days
E10F0 50 mg 695.00$ in stock
F10F0 100 mg 1190.00$ in stock

Azodibenzocyclooctyne (DBCO or ADIBO) is a stable but very reactive cycloalkyne for copper free Click chemistry.

This reagent is a conjugate of DBCO with Cyanine3 fluorophore for the non-catalyzed, strain promoted reaction with azides.

偶氮二苯并环辛炔（DBCO 或 ADIBO）是一种稳定但非常活泼的环炔烃，适用于无铜点击化学。

该试剂是 DBCO 与 Cyanine3 荧光团的结合物，用于与叠氮化物的非催化、应变促进反应。

Absorption and emission spectra of Cyanine3 fluorophore

Cyanine3 DBCO

Cyanine3 DBCO相关产品

Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

Cyanine5 是一种通用的红色发光染料，具有非常高的消光系数和良好的量子产率。 这种四嗪衍生物与反式环辛烯和环丙烯反应非常迅速，形成稳定的共轭物。

sulfo-Cyanine3 DBCO

Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.

Sulfo-Cyanine3 DBCO 是用于 Click Chemistry 的水溶性通用荧光团 sulfo-Cyanine3 的环炔衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cy7.5的胺反应性NHS酯。

General properties

Appearance: dark red powder 暗红色粉末
Molecular weight: 902.99
CAS number: 2692677-79-3
Molecular formula: C51H57N4O2PF6
Solubility: good in DMF, DMSO, DCM, alcohols, practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Azide-Terminated RAFT Polymers for Biological Applications. Current Protocols in Chemical Biology, 2020, 12(4), e85. doi: 10.1002/cpch.85
  2. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  3. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073

BDP FL DBCO

BDP FL DBCO,BDP FL 是一种用于 FAM（荧光素）通道的光稳定硼二吡咯亚甲基。 该染料与荧光素滤光片组兼容。

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  • BDP FL DBCO

BDP FL DBCO

标签：BDP FL, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A14F0 1 mg 110.00$ in stock
B14F0 5 mg 210.00$ in stock
C14F0 10 mg 310.00$ in stock
D14F0 25 mg 410.00$ in stock
E14F0 50 mg 695.00$ in stock
F14F0 100 mg 1190.00$ in stock

BDP FL DBCO

BDP FL is a photostable borondipyrromethene for FAM (fluorescein) channel. The dye is compatible with filter sets for fluorescein.

This is DBCO (azadibenzocyclooctyne) derivative for copper free Click chemistry reaction with azides.

BDP FL 是一种用于 FAM（荧光素）通道的光稳定硼二吡咯亚甲基。 该染料与荧光素滤光片组兼容。

这是用于与叠氮化物的无铜点击化学反应的 DBCO（氮杂二苯并环辛炔）衍生物。

Absorption and emission spectra of BDP FL

BDP FL DBCO

BDP FL DBCO相关产品

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

Sulfo-Cyanine5-PEG3-Biotin

Conjugate of biotin with sulfo-Cyanine5 emitting in the far-red region of the spectrum.

生物素与在光谱的远红色区域发射的 sulfo-Cyanine5 的结合物。

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.

BDP 650/665 炔烃是一种发红光的 BODIPY 染料衍生物，带有一个末端炔烃基团，用于铜催化与叠氮化物的共轭。 BDP 650/665 的吸收和发射光谱旨在适应各种仪器的 Cy5 通道。

General properties

Appearance: orange solid 橙色固体
Mass spec M+ increment: 592.3
Molecular weight: 592.49
CAS number: 2360493-46-3
Molecular formula: C35H35N4BF2O2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156

Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine,Sulfo-Cy7 是一种近红外水溶性荧光团。 该衍生物含有甲基四嗪基团，可在称为 TCO 连接的反应中与环烯烃进行快速、高效且无金属的共轭。

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  • Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine

标签：sulfo-Cyanine7,sulfo-Cy7, Near infrared (NIR) imaging, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
153E0 1 mg 110.00$ in stock
253E0 5 mg 290.00$ in stock
453E0 25 mg 690.00$ in stock
553E0 50 mg 1270.00$ in stock
653E0 100 mg 1990.00$ in stock

Sulfo-Cyanine7 is a near infrared, water soluble fluorophore. This derivative contains methyltetrazine group for the fast, efficient, and metal free conjugation with cycloalkenes in a reaction called TCO ligation.

Sulfo-Cy7 是一种近红外水溶性荧光团。 该衍生物含有甲基四嗪基团，可在称为 TCO 连接的反应中与环烯烃进行快速、高效且无金属的共轭。

Sulfo-Cyanine7 absorption and emission spectra

Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine相关产品

Cyanine3 tetrazine

Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.

荧光团 Cy3 的四嗪衍生物。 四嗪与应变烯烃（如反式环辛烯、环丙烯）和一些应变炔烃反应极快。

AF430 tetrazine

Tetrazine derivative of AF430 fluorescent dye suitable for in vitro cell labeling.

AF430 荧光染料的四嗪衍生物，适用于体外细胞标记。

Sulfo-Cyanine5.5 NHS ester

Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

NHS 酯形式的水溶性磺化远红色磺基-Cyanine5.5 染料。

General properties

Appearance: dark green solid  深绿色固体
Mass spec M+ increment: 863.3
Molecular weight: 930.19
Molecular formula: C47H52N7KO7S2
Solubility: good in DMF, DMSO, water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine,TCO（四嗪 – 反式环辛烯）连接是用于生物偶联的最快反应之一。 它是在四嗪和反式环辛烯或其他应变烯烃之间发生的逆电子需求[4+2] 环加成。

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  • Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine

标签：sulfo-Cyanine5,sulfo-Cy5, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
133E0 1 mg 110.00$ in stock
233E0 5 mg 290.00$ in stock
333E0 10 mg 460.00$ in stock
433E0 25 mg 690.00$ in stock
533E0 50 mg 1270.00$ in stock
633E0 100 mg 1990.00$ in stock

TCO (tetrazine – trans-cyclooctene) ligation is one of the fastest reactions used for bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.

Sulfo-Cyanine5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation based labeling.

This reagent possesses good aqueous solubility and stability in biological environments.

TCO（四嗪 – 反式环辛烯）连接是用于生物偶联的最快反应之一。 它是在四嗪和反式环辛烯或其他应变烯烃之间发生的逆电子需求[4+2] 环加成。

Sulfo-Cyanine5 四嗪是一种带有四嗪基团的荧光团衍生物，用于基于 TCO 连接的标记。

该试剂在生物环境中具有良好的水溶性和稳定性。

Absorption and emission spectra of Sulfo-Cyanine5

Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine相关产品

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

sulfo-Cyanine3 DBCO

Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.

Sulfo-Cyanine3 DBCO 是用于 Click Chemistry 的水溶性通用荧光团 sulfo-Cyanine3 的环炔衍生物。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cyanine5.5 DBCO 是一种远红色的水溶性试剂，用于与叠氮化物的无铜反应。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 864.09
Molecular formula: C42H46KN7O7S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

PEG3-tetrazine

PEG3-tetrazine,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。PEG3 四嗪是一种单反应性衍生物，可通过反电子需求 Diels-Alder 反应 (ied-DA) 与应变烯烃（例如反式环辛烯和一些环辛炔）轻松连接亲水性三甘醇片段（聚乙二醇化）。

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PEG3-tetrazine

标签：Tetrazine, Copper free Click chemistry, PEG3 (triethylene glycol)
货号 规格 价格 货期
1978-250mg 250 mg 370.00$ in stock
1978-1g 1 g 950.00$ in stock

PEG3 tetrazine is a monoreactive derivative that allows a facile attachment of hydrophilic triethyleneglycol fragment (pegylation) by inverse electron demand Diels-Alder reaction (ied-DA) with strained olefins, such as trans-cyclooctenes, and some cyclooctynes.

PEG3 四嗪是一种单反应性衍生物，可通过反电子需求 Diels-Alder 反应 (ied-DA) 与应变烯烃（例如反式环辛烯和一些环辛炔）轻松连接亲水性三甘醇片段（聚乙二醇化）。

PEG3-tetrazine相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头，具有羟基和炔烃片段。

General properties

Appearance: purple oil 紫油
Molecular weight: 334.37
Molecular formula: C16H22N4O4
IUPAC name: 2-(2-{2-[2-(6-Phenyl-1,2,4,5-tetraazin-3-yl)ethoxy]ethoxy}ethoxy)ethanol
Solubility: good in most organic solvents (excluding hydrocarbons)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

FAM tetrazine, 6-isomer

FAM tetrazine, 6-isomer,荧光素 (FAM) 是一种流行的荧光团，在可见光谱的绿色区域具有明亮的发射。 这种荧光素衍生物含有四嗪部分。 四嗪与反式环烯烃和其他应变烯烃在称为逆电子需求狄尔斯-阿尔德反应 (ied-DA) 的反应中发生反应。 反应非常迅速和特异。 该试剂含有纯的 FAM 6 异构体。

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  • FAM tetrazine, 6-isomer

FAM tetrazine, 6-isomer

标签：FAM (Fluorescein), Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
151E0 1 mg 110.00$ in stock
251E0 5 mg 210.00$ in stock
451E0 25 mg 410.00$ in stock
551E0 50 mg 695.00$ in stock
651E0 100 mg 1190.00$ in stock

Fluorescein (FAM) is a popular fluorophore that has bright emission in the green area of visible spectrum. This derivative of fluorescein contains tetrazine moiety. Tetrazines react with trans-cycloalkenes and other strained olefins in a reaction called inverse electron demand Diels-Alder reaction (ied-DA). The reaction is very quick and specific. The reagent contains pure 6-isomer of FAM.

荧光素 (FAM) 是一种流行的荧光团，在可见光谱的绿色区域具有明亮的发射。 这种荧光素衍生物含有四嗪部分。 四嗪与反式环烯烃和其他应变烯烃在称为逆电子需求狄尔斯-阿尔德反应 (ied-DA) 的反应中发生反应。 反应非常迅速和特异。 该试剂含有纯的 FAM 6 异构体。

FAM tetrazine, 6-isomer相关产品

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

Sulfo-Cyanine7 tetrazine

Near infrared, water soluble dye methyltetrazine for the conjugation with strained cycloalkenes in TCO ligation reaction.

近红外水溶性染料甲基四嗪用于在 TCO 连接反应中与应变环烯烃偶联。

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃，纯 6 异构体。

General properties

Appearance: orange solid 橙色固体
Mass spec M+ increment: 531.1
Molecular weight: 559.53
Molecular formula: C31H21N5O6
Solubility: good in DMF, DMSO, poor in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

FAM tetrazine, 5-isomer

FAM tetrazine, 5-isomer,Tetrazine (methyltetrazine) derivative of fluorescein, pure 5-isomer.储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

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  • FAM tetrazine, 5-isomer

FAM tetrazine, 5-isomer

标签：FAM (Fluorescein), Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
141E0 1 mg 110.00$ in stock
241E0 5 mg 210.00$ in stock
441E0 25 mg 410.00$ in stock
541E0 50 mg 695.00$ in stock
641E0 100 mg 1190.00$ in stock

Tetrazine (methyltetrazine) derivative of fluorescein, pure 5-isomer.

Tetrazines are reactive heterodiene components for [4+2] inverse electron demand Diels-Alder reaction (ied-DA) with strained cycloalkenes (trans-cyclooctenes, cyclopropenes). This reaction is also called TCO (tetrazine-cyclooctene) ligation. The reaction is among the fastest bioconjugation reactions.

荧光素的四嗪（甲基四嗪）衍生物，纯 5-异构体。

四嗪是与应变环烯烃（反式-环辛烯、环丙烯）发生 [4+2] 逆电子需求 Diels-Alder 反应 (ied-DA) 的反应性杂二烯组分。 该反应也称为 TCO（四嗪-环辛烯）连接。 该反应是最快的生物共轭反应之一。

FAM tetrazine, 5-isomer相关产品

BDP 630/650 tetrazine

BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.

BDP 630/650 是用于 Cyanine5 通道的硼二吡咯亚甲基染料。 这是一种用于与应变环烯烃偶联的四嗪衍生物。

BDP TR tetrazine

BDP TR is a borondipyrromethene fluorophore for ROX channel. The dye produces bright fluorescent emission. Tetrazines are reactive components for the conjugation with strained cycloalkenes.

BDP TR 是一种用于 ROX 通道的硼二吡咯亚甲基荧光团。 该染料产生明亮的荧光发射。 四嗪是与应变环烯烃共轭的反应组分。

BDP 581/591 tetrazine

BDP 581/591 is a borondipyrromethene dye with tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.

BDP 581/591 是一种带有四嗪基团的硼二吡咯亚甲基染料，用于逆电子需求 Diels-Alder (IEDDA) 连接。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 529.12
Molecular weight: 559.53
CAS number: 1619222-85-3
Molecular formula: C31H21N5O6
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

Cyanine7.5 tetrazine

Cyanine7.5 tetrazine,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。Cyanine7.5 tetrazine for tetrazine ligation contains a near infrared fluorophore suitable for in vivo imaging.

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Cyanine7.5 tetrazine

标签：Cyanine7.5,Cy7.5, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
160E0 1 mg 110.00$ in stock
260E0 5 mg 290.00$ in stock
460E0 25 mg 690.00$ in stock
560E0 50 mg 1270.00$ in stock
660E0 100 mg 1990.00$ in stock

Cyanine7.5 tetrazine for tetrazine ligation contains a near infrared fluorophore suitable for in vivo imaging.

Absorption and emission spectra of Cyanine7.5 are similar to ICG (indocyanine green), but Cyanine7.5 is significantly brighter.

用于四嗪连接的 Cyanine7.5 四嗪含有适合体内成像的近红外荧光团。

Cyanine7.5 的吸收和发射光谱与 ICG（吲哚菁绿）相似，但 Cyanine7.5 明显更亮。

Absorption and emission spectra of Cyanine7.5

Cyanine7.5 tetrazine

Cyanine7.5 tetrazine相关产品

Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

Cy5 是一种通用的红色发光染料，具有非常高的消光系数和良好的量子产率。 这种四嗪衍生物与反式环辛烯和环丙烯反应非常迅速，形成稳定的共轭物。

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

用于 TCO 连接的含有四嗪基团的近红外 Cy7 染料衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cy7.5的胺反应性NHS酯。

General properties

Appearance: dark colored solid
Mass spec M+ increment: 802.5
Molecular weight: 919.9
Molecular formula: C55H58N7BF4O
Solubility: good in DMF, DMSO, dichloromethane
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

Cyanine7 tetrazine

Cyanine7 tetrazine,TCO 连接是在四嗪和应变烯烃（例如反式-环辛烯）之间发生的反应。这种四嗪带有一个近红外染料的片段，Cyanine7。 这种 NIR 荧光团对于体内成像特别有用。

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  • Cyanine7 tetrazine

Cyanine7 tetrazine

标签：Cyanine7,Cy7, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
150E0 1 mg 110.00$ in stock
250E0 5 mg 290.00$ in stock
450E0 25 mg 690.00$ in stock
550E0 50 mg 1270.00$ in stock
650E0 100 mg 1990.00$ in stock

TCO ligation is a reaction that takes place between a tetrazine and a strained olefin, such as trans-cyclooctene.

This tetrazine bears a fragment of near infrared dye, Cyanine7. This NIR fluorophore is especially useful for in vivo imaging.

TCO 连接是在四嗪和应变烯烃（例如反式-环辛烯）之间发生的反应。

这种四嗪带有一个近红外染料的片段，Cyanine7。 这种 NIR 荧光团对于体内成像特别有用。

Absorption and emission spectra of Cyanine7

Cyanine7 tetrazine

Cyanine7 tetrazine相关产品

Cyanine5.5 tetrazine

A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.

一种含有 Cy5.5 荧光团、一种远红光发射染料和四嗪片段的化合物，用于通过 TCO 连接与反式环辛烯/环丙烯共轭。

Cyanine7.5 tetrazine

Cyanine7.5 is a NIR fluorescent dye with absorption and emission spectra similar to ICG (indocyanine green), but possessing a higher fluorescence quantum yield. This derivative is a tetrazine derivative for the TCO ligation reaction.

Cy7.5 是一种近红外荧光染料，其吸收和发射光谱类似于 ICG（吲哚菁绿），但具有更高的荧光量子产率。 该衍生物是用于 TCO 连接反应的四嗪衍生物。

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料，用于与叠氮化物的无铜点击化学缀合。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 703.4
Molecular weight: 877.94
Molecular formula: C47H54N7F6OP
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
CF260: 0.022
CF280: 0.029

Cyanine5.5 tetrazine

Cyanine5.5 tetrazine,Cy5.5 是一种远红发射染料，适用于体内成像和需要低背景的应用。 这种 Cy5.5 衍生物含有四嗪部分，可与反式环辛烯、环丙烯和一些应变的环辛炔反应形成稳定的共轭物。

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  • Cyanine5.5 tetrazine

Cyanine5.5 tetrazine

标签：Cyanine5.5,Cy5.5, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
170E0 1 mg 110.00$ in stock
270E0 5 mg 290.00$ in stock
470E0 25 mg 690.00$ in stock
570E0 50 mg 1270.00$ in stock
670E0 100 mg 1990.00$ in stock

Cyanine5.5 is a far red emitting dye for in vivo imaging and applications requiring low background. This Cyanine5.5 derivative contains tetrazine moiety that reacts with trans-cyclooctenes, cyclopropenes, and some strained cyclooctynes with the formation of stable conjugates.

This labeling reaction is extremely fast, and can be used in vivo.

Cy5.5 是一种远红发射染料，适用于体内成像和需要低背景的应用。 这种 Cy5.5 衍生物含有四嗪部分，可与反式环辛烯、环丙烯和一些应变的环辛炔反应形成稳定的共轭物。

这种标记反应非常快，可以在体内使用。

Absorption and emission spectra of Cyanine5.5

Cyanine5.5 tetrazine

Cyanine5.5 tetrazine相关产品

BDP R6G tetrazine

BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to rhodamine 6G. It contains tetrazine fragment for iedDA ligation.

BDP R6G 四嗪是一种硼二吡咯亚甲基染料，其吸收和发射波长与罗丹明 6G 相似。 它包含用于 iedDA 连接的四嗪片段。

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

General properties

Appearance: dark blue solid  深蓝色固体
Mass spec M+ increment: 737.4
Molecular weight: 911.96
Molecular formula: C50H52N7F6OP
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

BDP TR tetrazine

BDP TR tetrazine,BDP TR 染料四嗪衍生物，用于环烯烃与四嗪的 TCO 连接反应。

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  • BDP TR tetrazine

BDP TR tetrazine

标签：Tetrazine, BDP TR, Copper free Click chemistry
货号 规格 价格 货期
134E0 1 mg 110.00$ in stock
234E0 5 mg 290.00$ in stock
434E0 25 mg 690.00$ in stock
534E0 50 mg 1270.00$ in stock
634E0 100 mg 1990.00$ in stock

BDP TR dye tetrazine derivative for TCO ligation reaction of cycloalkenes with tetrazines.

BDP TR is a multi-purpose borondipyrromethene dye for ROX channel, possessing excellent brightness.

BDP TR 染料四嗪衍生物，用于环烯烃与四嗪的 TCO 连接反应。

BDP TR是一种用于ROX通道的多用途硼二吡咯亚甲基染料，具有优异的亮度。

Absorption and emission spectra of BDP TR

BDP TR tetrazine

BDP TR tetrazine相关产品

BDP 581/591 tetrazine

BDP 581/591 is a borondipyrromethene dye with tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.

BDP 581/591 是一种带有四嗪基团的硼二吡咯亚甲基染料，用于逆电子需求 Diels-Alder (IEDDA) 连接。

BDP 630/650 tetrazine

BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.

BDP 630/650 是用于 Cyanine5 通道的硼二吡咯亚甲基染料。 这是一种用于与应变环烯烃偶联的四嗪衍生物。

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

General properties

Appearance: violet crystals 紫水晶
Mass spec M+ increment: 577.2
Molecular weight: 607.44
Molecular formula: C31H24N7BF2O2S
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 60000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19

BDP R6G tetrazine

BDP R6G tetrazine,BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射波长接近罗丹明 6G (R6G)。 BDP R6G 是一种非常明亮且光稳定的染料。

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  • BDP R6G tetrazine

BDP R6G tetrazine

标签：Tetrazine, Copper free Click chemistry, BDP R6G
货号 规格 价格 货期
144E0 1 mg 110.00$ in stock
244E0 5 mg 290.00$ in stock
444E0 25 mg 690.00$ in stock
544E0 50 mg 1270.00$ in stock
644E0 100 mg 1990.00$ in stock

BDP R6G is a borondipyrromethene dye that has absorption and emission wavelengths close to rhodamine 6G (R6G). BDP R6G is a very bright and photostable dye.

Tetrazine fragment is used in inverse electron demand Diels Alder reaction with trans-cyclooctenes, acylazetines, and other strained olefins.

BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射波长接近罗丹明 6G (R6G)。 BDP R6G 是一种非常明亮且光稳定的染料。

四嗪片段用于与反式环辛烯、酰基氮杂环丁烷和其他应变烯烃的逆电子需求 Diels Alder 反应。

Absorption and emission spectra of BDP R6G

BDP R6G tetrazine

BDP R6G tetrazine相关产品

FAM tetrazine, 6-isomer

This molecule is a conjugate of FAM (fluorescein) – a bright fluorophore, and tetrazine – a reactive group that reacts with trans-cycloalkenes in a reaction called ied-DA (inverse electron demand Diels Alder reaction).

该分子是 FAM（荧光素）（一种明亮的荧光团）和四嗪（一种在称为 ied-DA（逆电子需求 Diels Alder 反应）的反应中与反式环烯烃反应的反应基团）的共轭物。

AF568 carboxylic acid

Non-reactive form of AF568 fluorescent dye

AF568 荧光染料的非反应性形式

AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

General properties

Appearance: orange to brown solid 橙色至棕色固体
Mass spec M+ increment: 495.2
Molecular weight: 523.34
Molecular formula: C28H24N7BF2O
Solubility: good in DMF, DMSO, DCM, poorly soluble in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL tetrazine

BDP FL tetrazine,与四嗪的逆电子需求 Diels-Alder 反应 (ied-DA) 是用于生物分子缀合的有前途的工具。 该反应发生在作为电子受体杂二烯的四嗪和应变的亲二烯体之间，例如反式-环辛烯、环丙烯或一些环辛炔。

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  • BDP FL tetrazine

BDP FL tetrazine

标签：BDP FL, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
114E0 1 mg 110.00$ in stock
214E0 5 mg 290.00$ in stock
414E0 25 mg 690.00$ in stock
514E0 50 mg 1270.00$ in stock
614E0 100 mg 1990.00$ in stock

Inverse electron demand Diels-Alder reaction (ied-DA) with tetrazines is a promising tool for the conjugation of biomolecules. The reaction takes place between tetrazine as an electron acceptor heterodiene, and a strained dienophile, such as trans-cyclooctene, cyclopropene, or some cyclooctynes.

Methyltetrazine provides greater stability in buffers than unsubstituted tetrazine. The rate of its reaction with cycloalkenes still beats almost all other conjugation reaction rates by a factor of magnitudes.

BDP FL is a bright dye for fluorescein (FAM) channel. Using BDP FL tetrazine, the dye can be conjugated with molecules bearing strained olefins.

与四嗪的逆电子需求 Diels-Alder 反应 (ied-DA) 是用于生物分子缀合的有前途的工具。 该反应发生在作为电子受体杂二烯的四嗪和应变的亲二烯体之间，例如反式-环辛烯、环丙烯或一些环辛炔。

与未取代的四嗪相比，甲基四嗪在缓冲液中的稳定性更高。 它与环烯烃的反应速率仍然比几乎所有其他共轭反应速率高出一个数量级。

BDP FL 是一种用于荧光素 (FAM) 通道的明亮染料。 使用 BDP FL 四嗪，染料可以与带有应变烯烃的分子结合。

Absorption and emission spectra of BODIPY FL

BDP FL tetrazine

BDP FL tetrazine相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cy5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性，推荐用于水环境中生物分子的标记。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯，用于标记蛋白质、肽和其他分子。

General properties

Appearance: red crystalline solid 红色结晶固体
Mass spec M+ increment: 447.2
Molecular weight: 475.3
CAS number: 2042193-77-9
Molecular formula: C24H24N7BF2O
Solubility: good in DCM, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

BDP 630/650 tetrazine

BDP 630/650 tetrazine,BDP 630/650 是一种具有红色发射的硼二吡咯亚甲基染料。 这种荧光团与需要最小背景时经常使用的 Cyanine5 通道相匹配。

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  • BDP 630/650 tetrazine

BDP 630/650 tetrazine

标签：Tetrazine, Copper free Click chemistry, BDP 630/650
货号 规格 价格 货期
154E0 1 mg 110.00$ in stock
254E0 5 mg 290.00$ in stock
454E0 25 mg 690.00$ in stock
554E0 50 mg 1270.00$ in stock
654E0 100 mg 1990.00$ in stock

BDP 630/650 is a borondipyrromethene dye with red emisssion. This fluorophore matches Cyanine5 channel that is often used when minimal background is desired.

Tetrazines react with trans-cyclooctenes in an ultra fast reaction called TCO ligation.

BDP 630/650 是一种具有红色发射的硼二吡咯亚甲基染料。 这种荧光团与需要最小背景时经常使用的 Cyanine5 通道相匹配。

四嗪与反式环辛烯在称为 TCO 连接的超快速反应中发生反应。

Absorption and emission spectra of BDP 630/650

BDP 630/650 tetrazine

BDP 630/650 tetrazine相关产品

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

ROX DBCO, 5-isomer

ROX (rhodamine X) is a bright rhodamine dye. This is a DBCO (dibenzocyclooctyne) derivative that has high reactivity against azides.

ROX（罗丹明 X）是一种明亮的罗丹明染料。 这是一种对叠氮化物具有高反应性的 DBCO（二苯并环辛炔）衍生物。

Sulfo-Cyanine3 amine

Water soluble cyanine dye with bright fluorescence, and high extinction coefficient. Contains an amino group for the conjugation with electrophiles, and enzymatic transamination labeling.

水溶性花青染料，荧光明亮，消光系数高。 包含用于与亲电试剂结合的氨基和酶促氨基转移标记。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 605.2
Molecular weight: 633.48
Molecular formula: C33H26N7BF2O2S
Solubility: good in many organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035