标签： Click chemistry

BDP 558/568 azide, BDP 558/568 叠氮化物

BDP 558/568 azide, BDP 558/568 叠氮化物,BDP 558/568 azide 是一种用于点击化学的具有叠氮化物官能团的硼二吡咯亚甲基染料。 其光谱接近Cyanine3通道。 荧光团已用作 BDP 558/568 C12 用于脂质追踪，但叠氮官能团可轻松与多种其他感兴趣的分子结合。

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BDP 558/568 azide

标签：Azides, Click chemistry, BDP 558/568
货号 规格 价格 货期
17430 1 mg 110.00$ in stock
27430 5 mg 210.00$ in stock
37430 10 mg 310.00$ in stock
47430 25 mg 410.00$ in stock
57430 50 mg 695.00$ in stock
67430 100 mg please inquire in stock

BDP 558/568 azide is a borondipyrromethene dye with azide functional group for Click chemistry. Its spectra are close to Cyanine3 channel. The fluorophore has been used for lipid tracking as BDP 558/568 C12, but azide functional groups allow easy conjugation with a wide variety of other molecules of interest.

BDP 558/568 azide 是一种用于点击化学的具有叠氮化物官能团的硼二吡咯亚甲基染料。 其光谱接近Cyanine3通道。 荧光团已用作 BDP 558/568 C12 用于脂质追踪，但叠氮官能团可轻松与多种其他感兴趣的分子结合。

Absorption and emission spectra of BDP 558/568

BDP 558/568 azide

BDP 558/568 azide, BDP 558/568 叠氮化物相关产品

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cyanine3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

氨基反应性 BDP FL，一种非常明亮且光稳定的荧光素通道染料。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 428.1
Molecular weight: 428.27
Molecular formula: C19H19N6BF2OS
Solubility: soluble in many organic solvents (DCM, acetone, alcohols, DMF, DMSO), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07

3-азидопропиламин,3-叠氮基丙胺

3-азидопропиламин,3-叠氮基丙胺

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3-азидопропиламин,3-叠氮基丙胺

Azides, Amines, Click chemistry
货号 规格 价格 货期
58-100mg 100 mg 110.00$ 21 days
58-1g 1 g 400.00$ 21 days
58-5g 5 g please inquire 21 days

Азидопропиламин-реагент с терминальными амино- и азидогруппами, широко используемый в реакциях Click Chemistry и хорошо растворимый в воде.

Азидопропиламин применяется для введения азидного фрагмента в молекулы, содержащие карбоксильные группы с помощью активации последних карбодиимидом и взаимодействия с аминогруппой 3-азидопропиламина. Подобные соединения с терминальной азидной группой могут вступать в реакции Cu(I)-катализируемого азидо-алкинового [3+2]-циклоприсоединения.

Также азидопропиламин может использоваться в пептидном синтезе для модификации пептидов с активированными HBTU и HOBt карбоксильными группами.

叠氮基丙胺是一种具有末端氨基和叠氮基的试剂，广泛用于点击化学反应，极易溶于水。

叠氮基丙胺用于通过用碳二亚胺活化后者并与 3-叠氮基丙胺的氨基相互作用，将叠氮片段引入含有羧基的分子中。具有末端叠氮基的类似化合物可以进入 Cu(I) 催化的叠氮基-炔烃 [3+2]-环加成反应。

叠氮基丙胺也可用于肽合成，以修饰具有活化 HBTU 和 HOBt 羧基的肽。

Общие свойства

Вид продукта: бесцветная жидкость 无色液体
Молекулярная масса: 100.12
CAS-номер: 88192-19-2
Брутто-формула: C3H8N4
Название IUPAC: 3-Azido-1-propanamine
Растворимость: растворим в воде, ДМСО, ДМФ, дихлорметане, ТГФ, хлороформе

溶于水、DMSO、DMF、二氯甲烷、THF、氯仿
Контроль качества: ЯМР 1H, ГХ-МС (95%)
Условия хранения: Хранение: 24 месяца (с момента доставки) при -20°C в темноте. Транспортировка: до трех недель при комнатной температуре.

储存：-20°C 避光保存 24 个月（从交货开始）。 运输：室温下最多三周。
MSDS: Download
Product specifications

THPTA ligand

THPTA ligand,THPTA 配体（三羟丙基三唑基甲胺）是一种用于水基铜催化点击化学反应的三唑配体。 该试剂具有很好的水溶性。 当不希望使用有机共溶剂时，它特别适用于点击化学标记和蛋白质（包括抗体）缀合。

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THPTA ligand

标签：Click chemistry
货号 规格 价格 货期
F4050 100 mg 40.00$ in stock
H4050 500 mg 199.00$ in stock
I4050 1 g 369.00$ in stock
K4050 5 g 1568.00$ in stock

THPTA ligand (tris-hydroxypropyltriazolylmethylamine) is a triazole ligand for water based copper catalyzed Click chemistry reactions. This reagent is very well water soluble. It is especially useful for Click chemistry labeling and conjugation of proteins including antibodies, when organic co-solvents are undesirable.

THPTA 配体（三羟丙基三唑基甲胺）是一种用于水基铜催化点击化学反应的三唑配体。 该试剂具有很好的水溶性。 当不希望使用有机共溶剂时，它特别适用于点击化学标记和蛋白质（包括抗体）缀合。

THPTA ligand THPTA ligand THPTA ligand THPTA ligand

THPTA ligand相关产品

BDP 650/665 azide

BDP 650/665 is a red-emitting borondipyrromethene dye. This azide derivative can be conjugated with alkynes and cycloalkynes.
BDP 650/665 是一种发红光的硼二吡咯亚甲基染料。 这种叠氮化物衍生物可以与炔烃和环炔烃共轭。

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling
用于蛋白质标记的 Cy2 NHS 酯最小染料

FAM NHS ester, 6-isomer

Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.
荧光素的活化 N-羟基琥珀酰亚胺酯 (FAM)，纯 6-异构体。

General properties

Appearance: off white solid
Molecular weight: 434.5
CAS number: 760952-88-3
Molecular formula: C18H30N10O3
IUPAC name: 3-[4-[[bis[[1-(3-hydroxypropyl)triazol-4-yl]methyl]amino]methyl]triazol-1-yl]propan-1-ol
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

相关文献：

  1. Rudack, T.; Teuber, C.; Scherlo, M.; Güldenhaupt, J.; Schartner, J.; Lübben, M.; Klare, J.P.; Gerwert, K.; Kötting, C. The Ras Dimer Structure. ChemRxiv, preprint. doi: 10.26434/chemrxiv.14039810.v1
  2. Wilder, L.M. Handali, P.R.; Webb, L.J.; Crooks, R.M. Interactions between Oligoethylene Glycol-Capped AuNPs and Attached Peptides Control Peptide Structure. Bioconjugate Chemistry, 2020, 31(10), 2383–2391. doi: 10.1021/acs.bioconjchem.0c00447
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Hahn, F.; Niesar, A.; Wangen, C.; Wild, M.; Grau, B.; Herrmann, L.; Capci, A.; Adrait, A.; Couté, Y.; Tsogoeva, S.B.; Marschall, M. Target verification of artesunate-related antiviral drugs: assessing the role of mitochondrial and regulatory proteins by click chemistry and fluorescence labeling. Antiviral Research, 2020, 180, 104861. doi: 10.1016/j.antiviral.2020.104861

DMSO, labeling grade

DMSO, labeling grade,DMSO 是一种广泛用于生物偶联的极性非质子溶剂。 这种溶剂可以被认为是点击反应非常重要的助溶剂，可以用水溶性差的荧光染料标记各种物体。 当疏水性标记用于蛋白质标记时，或者当标记分子需要在反应前被等分时，DMSO 也被推荐作为反应混合物中的辅助溶剂。

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DMSO, labeling grade

标签：Click chemistry,Protein labeling
货号 规格 价格 货期
15050 1 mL 10.00$ in stock

DMSO is a polar aprotic solvent widely used in bioconjugation. This solvent can be considered as very important co-solvent for Click reactions to label various objects with poorly water-soluble fluorescent dyes. DMSO is also recommended as an auxiliary solvent in the reaction mixture when a hydrophobic label is used for protein labeling, or when a label molecule needs to be aliquoted before the reaction.

DMSO 是一种广泛用于生物偶联的极性非质子溶剂。 这种溶剂可以被认为是点击反应非常重要的助溶剂，可以用水溶性差的荧光染料标记各种物体。 当疏水性标记用于蛋白质标记时，或者当标记分子需要在反应前被等分时，DMSO 也被推荐作为反应混合物中的辅助溶剂。

DMSO, labeling grade DMSO, labeling grade DMSO, labeling grade DMSO, labeling grade

DMSO, labeling grade相关产品

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cy5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

BDP 581/591 hydrazide

BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

BDP 581/591 是一种具有明亮发射的多用途染料。 这是一种用于与醛和酮结合的酰肼染料。

General properties

Appearance: colorless liquid
Molecular weight: 78.14
CAS number: 67-68-5
Molecular formula: C2H6OS
IUPAC name: dimethylsulfoxide
Solubility: miscible with water, many organic solvents
Quality control: GCMS (98+%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO,铜 (II)-TBTA 配合物是用于 Click Chemistry 共轭反应的催化剂组分。 实际催化剂含有 Cu(I)，但该试剂不能储存，应由铜(II)-TBTA 配合物通过还原原位生成。 为了活化这种催化剂，应将还原剂如抗坏血酸添加到反应混合物中。

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Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

标签：Click chemistry
货号 规格 价格 货期
21050 1.5 mL 55.00$ in stock
Copper (II)-TBTA complex is a component of catalyst used for Click Chemistry conjugation reaction. Actual catalyst contains Cu(I), but this reagent cannot be stored, and should be generated from Copper(II)-TBTA complex in situ by reduction. To activate this catalyst, reductant such as ascorbic acid should be added to reaction mixture.
铜 (II)-TBTA 配合物是用于 Click Chemistry 共轭反应的催化剂组分。 实际催化剂含有 Cu(I)，但该试剂不能储存，应由铜(II)-TBTA 配合物通过还原原位生成。 为了活化这种催化剂，应将还原剂如抗坏血酸添加到反应混合物中。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO相关产品

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

香豆素 343 是一种蓝色荧光团，可作为荧光素 (FAM) 的 FRET 供体。 这种叠氮化物衍生物可以通过点击化学与炔烃结合。 荧光团和叠氮化物基团之间的延伸连接臂增强了溶解度，并提供了染料和生物分子之间的空间分离。

General properties

Appearance: blue solution
Molecular weight: 690.23
Molecular formula: C30H30CuN10O4S
Quality control: functional testing (Click Chemistry)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

相关文献：

  1. Wang, Y.; Kathiresan, V.; Chen, Y.; Hu, Y.; Jiang, W.; Bai, G.; Liu, G.; Qin, P.Z.; Fang, X. Posttranscriptional Site-Directed Spin Labeling of Large RNAs with an Unnatural Base Pair System Under Non-Denaturing Conditions. ChemRxiv, preprint. doi: 10.26434/chemrxiv.12058914
  2. Novopashina, D.S.; Vorobyeva, M.A.; Lomzov, A.A.; Silnikov, V.N.; Venyaminova, A.G. Terminal Mono- and Bis-Conjugates of Oligonucleotides with Closo-Dodecaborate: Synthesis and Physico-Chemical Properties. International Journal of Molecular Sciences, 2021, 22(1), 182. doi: 10.3390/ijms22010182
  3. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  4. Blanchard, A.T.; Bazrafshan, A.S.; Yi, J.; Eisman, J.T.; Yehl, K.M.; Bian, T.; Mugler, A.; Salaita, K. Highly Polyvalent DNA Motors Generate 100+ pN of Force via Autochemophoresis. Nano Letters, 2019, 19(10), 6977–6986. doi: 10.1021/acs.nanolett.9b02311

Click chemistry buffer, 1.5x

Click chemistry buffer, 1.5x,Click 化学的催化缓冲液含有铜 (II)、乙酸三乙铵、pH 7 和 DMSO。 缓冲液是 1.5x 浓缩液，是一种即用型试剂，用于修饰寡核苷酸或小分子等核酸。

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Click chemistry buffer, 1.5x

标签：Click chemistry
货号 规格 价格 货期
61150 55 mL 49.00$ 5 days
Catalytic buffer for Click chemistry contains copper(II), triethylammonium acetate, pH 7, and DMSO. The buffer is a 1.5x concentrate, a ready-to-use reagent for the modification of nucleic acids such as oligonucleotides, or small molecules.

Copper(II) should be reduced to copper(I) prior to reaction. Ascorbic acid is the recommended reductant.

Click 化学的催化缓冲液含有铜 (II)、乙酸三乙铵、pH 7 和 DMSO。 缓冲液是 1.5x 浓缩液，是一种即用型试剂，用于修饰寡核苷酸或小分子等核酸。

反应前应将铜 (II) 还原为铜 (I)。 抗坏血酸是推荐的还原剂。

Click chemistry buffer, 1.5x Click chemistry buffer, 1.5x Click chemistry buffer, 1.5x

Click chemistry buffer, 1.5x相关产品

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

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General properties

Appearance: bluish liquid
Storage conditions: Storage: 24 months after receival at +4 or -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存：收到后 24 个月，在 +4 或 -20°C 下避光保存。 运输：在室温下长达 3 周。
MSDS: Download
Product specifications

Ascorbic acid抗坏血酸

Ascorbic acid抗坏血酸,抗坏血酸是将铜 (II)-TBTA 复合物还原为活性铜 (I) 形式的推荐试剂。

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Ascorbic acid

标签：Click chemistry
货号 规格 价格 货号
12050 10 mg 20.00$ in stock

Ascorbic acid is the recommended reagent for reduction of the Copper(II)-TBTA complex into the active Copper(I) form.

抗坏血酸是将铜 (II)-TBTA 复合物还原为活性铜 (I) 形式的推荐试剂。

Ascorbic acid Ascorbic acid Ascorbic acid Ascorbic acid

Ascorbic acid抗坏血酸相关产品

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling

Sulfo-Cyanine7 azide

Water-soluble NIR fluorescent dye azide for Click chemistry
用于点击化学的水溶性 NIR 荧光染料叠氮化物

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
用于与活化酯和环氧化物偶联的Cy5 胺官能化染料。

General properties

Appearance: colorless solid
Molecular weight: 176.12
CAS number: 50-81-7
Molecular formula: C6H8O6
Solubility: good in water
Quality control: functional testing
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

相关文献：

  1. Novopashina, D.S.; Vorobyeva, M.A.; Lomzov, A.A.; Silnikov, V.N.; Venyaminova, A.G. Terminal Mono- and Bis-Conjugates of Oligonucleotides with Closo-Dodecaborate: Synthesis and Physico-Chemical Properties. International Journal of Molecular Sciences, 2021, 22(1), 182. doi: 10.3390/ijms22010182
  2. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586
  3. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646
  4. Samuelsen, S.V.; Maity, A.; Nybo, M.; Macaubas, C.; Lønstrup, L.; Balboni, I.M.; Mellins, E.D.; Astakhova, K. Novel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune Diseases. PLoS One, 2016, 11(6), e0156125. doi: 10.1371/journal.pone.0156125

Azide-PEG4-Azide

Azide-PEG4-Azide,PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰，或者通过铜催化与末端炔烃的反应，或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

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Azide-PEG4-Azide

标签：Azides,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1865-1g 1 g 90.00$ in stock
1865-5g 5 g 250.00$ in stock
1865-25g 25 g 950.00$ in stock
PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by Click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.

This diazide is useful for the synthesis of dimeric molecules by Click chemistry.

PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰，或者通过铜催化与末端炔烃的反应，或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

这种二叠氮化物可用于通过点击化学合成二聚体分子。

Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide

Azide-PEG4-Azide相关产品

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯，用于标记蛋白质、肽和其他分子。

General properties

Appearance: colorless liquid
Molecular weight: 244.25
CAS number: 101187-39-7
Molecular formula: C8H16N6O3
Solubility: miscible with water, polar organic solvents
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
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Azide-PEG4-Amine

Azide-PEG4-Amine,低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å，因此 PEG4 的长度约为 14 Å (1.4 nm)。

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Azide-PEG4-Amine

标签：Azides,Amines,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1868-1g 1 g 90.00$ in stock
1868-5g 5 g 250.00$ in stock
1868-25g 25 g 950.00$ in stock
Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so that the length of PEG4 is around 14 Å (1.4 nm).

Azide-PEG4-Amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds, and an azide group that is suitable for Click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å，因此 PEG4 的长度约为 14 Å (1.4 nm)。

叠氮化物-PEG4-Amine 是一种双官能化合物，具有可通过活化酯或类似羰基化合物酰化修饰的胺基，以及适用于 Click 化学反应的叠氮基。 PEG4 具有高度亲水性和生物相容性。

Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine

Azide-PEG4-Amine相关产品

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

一种双功能连接分子，包含用于点击化学的末端炔烃部分和胺基。 包含一个长的亲水性 PEG4 臂。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

General properties

Appearance: colorless to yellowish liquid
Molecular weight: 218.25
CAS number: 134179-38-7
Molecular formula: C8H18N4O3
Solubility: miscible with water, polar organic solvents
Quality control: NMR 1H,GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

Azide-PEG3-Azide

Azide-PEG3-Azide,PEG3（三甘醇）二叠氮化物（1,8-diazido-3,6-dioxaoctane）是一种对称的双功能交联剂，带有两个叠氮基。

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Azide-PEG3-Azide

标签：Azides,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
207-1g 1 g 95.00$ in stock
207-5g 5 g 390.00$ in stock
207-25g 25 g please inquire in stock
PEG3 (triethylene glycol) diazide (1,8-diazido-3,6-dioxaoctane) is a symmetrical bifunctional crosslinker bearing two azide groups.
PEG3（三甘醇）二叠氮化物（1,8-diazido-3,6-dioxaoctane）是一种对称的双功能交联剂，带有两个叠氮基。

Azide-PEG3-Azide Azide-PEG3-Azide Azide-PEG3-Azide > Azide-PEG3-Azide

Azide-PEG3-Azide相关产品

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 200.2
CAS number: 59559-06-7
Molecular formula: C6H12N6O2
IUPAC name: 1,8-diazido-3,6-dioxaoctane, 1,2-bis(2-azidoethoxy)ethane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  2. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f

Azide-PEG3-Amine

Azide-PEG3-Amine,叠氮化物-PEG3-胺是一种双功能试剂，具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物（通过胺基的酰化）与炔烃（通过点击化学反应）的缀合。

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Azide-PEG3-Amine

标签：Azides,Amines,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
218-1g 1 g 95.00$ in stock
218-5g 5 g 280.00$ in stock
218-25g 25 g please inquire in stock
Azide-PEG3-amine is a bifunctional reagent with an azide group, and an amine group flanking triethylene glycol. This linker is useful for the conjugation of carboxylic derivatives (by acylation of the amine group) with alkynes (via a Click chemistry reaction).
叠氮化物-PEG3-胺是一种双功能试剂，具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物（通过胺基的酰化）与炔烃（通过点击化学反应）的缀合。

Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine

Azide-PEG3-Amine相关产品

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

General properties

Appearance: colorless/yellowish oil
Molecular weight: 174.2
CAS number: 166388-57-4
Molecular formula: C6H14N4O2
IUPAC name: 1-Amino-8-azido-3,6-dioxaoctane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GCMS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

Pentynoic acid STP ester

Pentynoic acid STP ester,这种水溶性炔烃活化酯试剂用于将炔烃基团连接到各种生物分子，如蛋白质和肽。 也可以使用氨基-DNA和其他胺。 由于天然蛋白质不含炔烃，但几乎总是含有胺（赖氨酸），这种分子是将天然胺转化为炔烃的“适配器”。

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Pentynoic acid STP ester

货号 规格 价格 货期
30720 10 mg 110.00$ in stock
40720 25 mg 210.00$ 5 days
50720 50 mg 410.00$ in stock
60720 100 mg 695.00$ 5 days

This water soluble alkyne activated ester reagent is used for the attachment of alkyne group to variois biomolecules such as proteins, and peptides. Amino-DNA, and other amines can be used as well. Since natural proteins do not contain alkynes, but almost always contain amines (lysines), this molecule is an “adaptor” to turn natural amines into alkynes.

Use this product to enable any of your proteins for Click Chemistry.

This is an STP (sulfotetrafluorophenyl) ester. STP esters are similar to NHS esters, but possess higher hydrophilicity, and water solubility. It works fine in pure aqueous reactions without addition of organic co-solvent, and is best suited for the modification of proteins.

这种水溶性炔烃活化酯试剂用于将炔烃基团连接到各种生物分子，如蛋白质和肽。 也可以使用氨基-DNA和其他胺。 由于天然蛋白质不含炔烃，但几乎总是含有胺（赖氨酸），这种分子是将天然胺转化为炔烃的“适配器”。

使用此产品可让您的任何蛋白质用于 Click Chemistry。

这是一种 STP（磺基四氟苯基）酯。 STP 酯与 NHS 酯相似，但具有更高的亲水性和水溶性。 它在不添加有机助溶剂的纯水反应中表现良好，最适合蛋白质的修饰。

Pentynoic acid STP ester相关产品

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

TAMRA amine, 5-isomer

TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).

TAMRA（四甲基罗丹明）染料，纯 5-异构体，带有一个胺基，可与亲电子试剂（NHS 酯、环氧化物等）结合。

Cyanine3 NHS ester minimal dye

Cyanine3 minimal dye for protein labeling.

用于蛋白质标记的 Cy3 最小染料。

General properties

Appearance: colorless solid
Mass spec M+ increment: 80.0
Molecular weight: 348.20
CAS number: 1807530-14-8
Molecular formula: C11H5F4NaO5S
IUPAC name: 4-​Pentynoic acid, 2,​3,​5,​6-​tetrafluoro-​4-​sulfophenyl ester, sodium salt
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
  2. Abbasov, M.E.; Kavanagh, M.E.; Ichu, T.-A.; Lazear, M.R.; Tao, Y.; Crowley, V.M.; am Ende, C.W.; Hacker, S.M.; Ho, J.; Dix, M.M.; Suciu, R.; Hayward, M.M.; Kiessling, L.L.; Cravatt, B.F. A proteome-wide atlas of lysine-reactive chemistry. Nature Chemistry, 2021, 13(11), 1081–1092. doi: 10.1038/s41557-021-00765-4
  3. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  4. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586

Hexynoic acid STP ester

Hexynoic acid STP ester,炔烃活化酯，用于标记蛋白质、肽和其他带有脂肪族胺官能团的分子中的胺基。

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Hexynoic acid STP ester

标签：NHS esters, Alkynes,Click chemistry
货号 规格 价格 货期
569-25mg 25 mg 95.00$ in stock
569-100mg 100 mg 185.00$ in stock
569-500mg 500 mg 850.00$ in stock

Alkyne activated ester for the labeling of amine groups in proteins, peptides and other molecules bearing aliphatic amine functional groups.

Sulfotetrafluorophenyl (STP) esters are excellent alternatives to conventional N-hydroxysuccinimide (NHS) esters. Compared to NHS esters, STP esters provide better ratio of labeling to hydrolysis in aqueous environments.

Hexynoic acid fragment is a short linker with amine. For longer amine linkers, consider using Alkyne-PEG activated esters.

炔烃活化酯，用于标记蛋白质、肽和其他带有脂肪族胺官能团的分子中的胺基。

磺基四氟苯基 (STP) 酯是传统 N-羟基琥珀酰亚胺 (NHS) 酯的绝佳替代品。 与 NHS 酯相比，STP 酯在水环境中提供更好的标记与水解比率。

己烯酸片段是与胺的短接头。 对于更长的胺接头，考虑使用炔烃-PEG 活化酯。

Hexynoic acid STP ester相关产品

DBCO STP ester

Activated ester for modification of proteins/antibodies/peptides followed by introduction into copper-free Click Chemistry reaction.

用于修饰蛋白质/抗体/肽的活化酯，然后引入无铜点击化学反应。

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

用于肽和蛋白质的叠氮基标记的活化酯。

Alkyne-PEG3-NHS ester

Bifunctional hyrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).

基于三甘醇 (PEG3) 的具有 NHS 酯和末端炔烃官能团的双功能亲水接头。

General properties

Appearance: white solid 白色固体
Mass spec M+ increment: 94.04
Molecular weight: 362.23
Molecular formula: C12H7F4O5SNa
IUPAC name: Sodium 4-(hex-5-ynoyloxy)-2,3,5,6-tetrafluorophenylsulfonate
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
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EdU (5-ethynyl-2′-deoxyuridine)

EdU (5-ethynyl-2′-deoxyuridine),EdU（乙炔基脱氧尿苷）是一种核苷，是胸苷的类似物，带有一个乙炔基。 这种核苷充当细胞 DNA 复制机器的底物。 然后，可以通过点击化学反应与各种染料叠氮化物形成含有乙炔基的 DNA。 荧光 DNA 可以通过显微镜检测，或者细胞可以通过 FACS 分选。

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EdU (5-ethynyl-2′-deoxyuridine)

货号 规格 价格 货期
10540 100 mg 120.00$ in stock
20540 250 mg 195.00$ in stock
30540 500 mg 345.00$ in stock
40540 1 g 590.00$ in stock

EdU (ethynyldeoxyuridine) is a nucleoside, an analog of thymidine, carrying an ethynyl group. This nucleoside behaves as a substrate for cellular DNA replication machinery. Then, DNA containing ethynyl groups can be developed by Click chemistry reaction with various dye azides. Fluorescent DNA can be detected by microscopy, or cells can be sorted by FACS.

EdU（乙炔基脱氧尿苷）是一种核苷，是胸苷的类似物，带有一个乙炔基。 这种核苷充当细胞 DNA 复制机器的底物。 然后，可以通过点击化学反应与各种染料叠氮化物形成含有乙炔基的 DNA。 荧光 DNA 可以通过显微镜检测，或者细胞可以通过 FACS 分选。

EdU (5-ethynyl-2′-deoxyuridine)相关产品

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.

Sulfo-Cy5 是一种用于 Click 化学的水溶性 Cy5 染料炔烃。

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

Sulfo-Cyanine5.5 azid

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cy5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性，推荐用于水环境中生物分子的标记。

General properties

Appearance: light beige to light brown solid浅米色至浅棕色固体
Molecular weight: 252.22
CAS number: 61135-33-9
Molecular formula: C11H12N2O5
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。
MSDS: Download
Product specifications

相关文献：

  1. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  2. Lyu, X.; Lei, K.-H.; Biak Sang, P.; Shiva, O.; Chastain, M.; Chi, P.; Chai, W. Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA. EMBO Journal, 2021, 40(2), e103654. doi: 10.15252/embj.2019103654
  3. Irwin, N.A.T.; Pittis, A.A.; Mathur, V.; Howe, L.J.; Keeling, P.J.; Lynn, D.H.; Bourland, W.A. The Function and Evolution of Motile DNA Replication Systems in Ciliates. Current Biology, 2021, 31(1), 66–76.e6. doi: 10.1016/j.cub.2020.09.077
  4. Wang, Z.; Cui, M.; Shah, A.M.; Tan, W.; Liu, N.; Bassel-Duby, R.; Olson, E.N. Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution. Cell Reports, 2020, 33(10), 108472. doi: 10.1016/j.celrep.2020.108472

EU (5-ethynyl uridine)

EU (5-ethynyl uridine),5-乙炔基尿苷 (EU) 是用于 RNA 合成研究的常用分子生物学试剂。

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EU (5-ethynyl uridine)

货号 规格 价格 货期
2439-25mg 25 mg 129.00$ in stock
2439-500mg 500 mg 950.00$ in stock

5-ethynyl uridine (EU) is a commonly used molecular biology reagent for RNA synthesis studies.

EU is readily taken up by living cells and phosphorylated through the pyrimidine salvage pathway. Generated 5-ethynyl uridine-5’-triphosphate is incorporated by RNA polymerases I, II, and III into de novo RNA instead of uridine, but not into DNA.

EU-labeled nascent cellular RNA can be detected quickly and with high sensitivity via Click Chemistry following fluorescent visualization. Alkyne group attached at the 5-position of uridine in modified RNA reacts with dye or biotin azides via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC).

Labeled RNA can be detected with different methods, e.g. fluorescent microscopy or flow cytometry, which allows estimating transcriptional levels in the cells.

5-ethynyl uridine has an advantage over its analog, 5-bromouridine, because azide-containing dyes are very small in size and exhibit better membrane permeability compared to antibodies used for the detection of 5-bromouridine. Thus, the Сlick Сhemistry approach allows whole-mount staining of large samples like organs or tissue fragments.

5-乙炔基尿苷 (EU) 是用于 RNA 合成研究的常用分子生物学试剂。

EU 很容易被活细胞吸收并通过嘧啶补救途径磷酸化。生成的 5-乙炔基尿苷-5′-三磷酸被 RNA 聚合酶 I、II 和 III 整合到从头 RNA 中，而不是整合到 DNA 中。

EU 标记的新生细胞 RNA 可以在荧光可视化后通过 Click Chemistry 快速且高灵敏度地检测到。连接在修饰 RNA 中尿苷 5 位的炔基通过 Cu(I) 催化的叠氮化物-炔烃环加成 (CuAAC) 与染料或生物素叠氮化物反应。

标记的 RNA 可以用不同的方法检测，例如荧光显微镜或流式细胞术，可以估计细胞中的转录水平。

5-乙炔基尿苷优于其类似物 5-溴尿苷，因为与用于检测 5-溴尿苷的抗体相比，含叠氮化物的染料尺寸非常小并且表现出更好的膜渗透性。因此，Сlick Сhemistry 方法允许对器官或组织碎片等大样本进行整体染色。

EU (5-ethynyl uridine)相关产品

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

General properties

Appearance: off white solid
Molecular weight: 268.22
CAS number: 69075-42-9
Molecular formula: C11H12N2O6
IUPAC name: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

DBCO STP ester

DBCO STP ester,二苯并环辛炔磺基四氟苯酯（DBCO STP 酯）是一种水溶性试剂，可用于修饰含有 -NH2 基团的肽、抗体、蛋白质和其他分子。

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DBCO STP ester

标签：Cycloalkyne,Non-fluorescent alkynes,Click chemistry
货号 规格 价格 货期
2584-5mg 5 mg – 10 days
2584-10mg 10 mg 90.00$ in stock
2584-25mg 25 mg 180.00$ in stock
2584-100mg 100 mg 450.00$ in stock
2584-500mg 500 mg 1700.00$ in stock
2584-1g 1 g 3000.00$ in stock
2584-5g 5 g please inquire 21 days

 

Dibenzocyclooctyne sulfotetrafluorophenyl ester (DBCO STP ester) is a water-soluble reagent that can be used for the modification of peptides, antibodies, proteins, and other molecules containing the -NH2 group.

STP esters are hydrolyzed much more slowly than NHS esters, thus allowing efficient biomolecule modification in the aqueous medium.

The dibenzocyclooctyne (DBCO) moiety, which is also known as ADIBO or DIBAC, is the most common substrate for copper-free Click Chemistry reactions that are promoted by ring strain. In this reaction in the presence of a Cu(I) catalyst, DBCO derivatives react with biomolecules functionalized by the azide group to result in stable triazoles.

二苯并环辛炔磺基四氟苯酯（DBCO STP 酯）是一种水溶性试剂，可用于修饰含有 -NH2 基团的肽、抗体、蛋白质和其他分子。

STP 酯的水解速度比 NHS 酯慢得多，因此可以在水性介质中进行有效的生物分子修饰。

二苯并环辛炔 (DBCO) 部分，也称为 ADIBO 或 DIBAC，是由环应变促进的无铜点击化学反应的最常见底物。 在该反应中，在 Cu(I) 催化剂的存在下，DBCO 衍生物与被叠氮基官能化的生物分子反应生成稳定的三唑。

DBCO STP ester相关产品

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

Hexynoic acid STP ester

Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.

用于修饰胺基的炔烃活化酯。 STP 酯基是 NHS 酯官能团的绝佳替代品。

Pentynoic acid STP ester

An activated ester for the introduction of alkyne into peptides/proteins.

用于将炔烃引入肽/蛋白质的活化酯。

General properties

Appearance: beige powder
Molecular weight: 569.46
Molecular formula: C26H16NF4O6Sa
Solubility: good in water, DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Biotin alkyne

Biotin alkyne,生物素炔烃，用于通过 Click Chemistry 制备各种生物素化偶联物。储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。

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Biotin alkyne

标签：Alkynes,Biotin alkyne,Click chemistry
货号 规格 价格 货期
C37B0 10 mg 90.00$ in stock
D37B0 25 mg 160.00$ in stock
E37B0 50 mg 270.00$ in stock
F37B0 100 mg 420.00$ in stock

Biotin alkyne for the preparation of various biotinylated conjugates via Click Chemistry.

This alkyne reacts with various azides, including biomolecules containing azide groups. Biotinylated conjugates can be used for various assays and applications requiring affinity binding.

Our recommended protocol can be used for the conjugation.

生物素炔烃，用于通过 Click Chemistry 制备各种生物素化偶联物。

该炔烃与各种叠氮化物反应，包括含有叠氮化物基团的生物分子。 生物素化缀合物可用于需要亲和结合的各种测定和应用。

我们推荐的协议可用于缀合。

Biotin alkyne相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

1-Ethynyl pyrene

Pyrene is polyaromatic hydrocarbon containing four fused rings. This reagent contains terminal alkyne group for Click Chemistry and other reactions, such as Sonogashira coupling.

芘是含有四个稠环的多环芳烃。 该试剂包含用于 Click Chemistry 和其他反应（如 Sonogashira 偶联）的末端炔基。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: colorless solid 无色固体
Molecular weight: 281.37
CAS number: 773888-45-2
Molecular formula: C13H19N3O2S
Solubility: good in DMSO and DMF, low in water
Quality control: NMR 1H (95%), TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。
MSDS: Download
Product specifications

相关文献：

  1. Bin Rashed, F.; Stoica, A.C.; MacDonald, D.; El-Saidi, H.; Ricardo, C.; Bhatt, B.; Moore, J.; Diaz-Dussan, D.; Ramamonjisoa, N.; Mowery, Y.; Damaraju, S.; Fahlman, R.; Kumar, P.; Weinfeld, M. Identification of proteins and cellular pathways targeted by 2-nitroimidazole hypoxic cytotoxins. Redox Biology, 2021, 41, 101905. doi: 10.1016/j.redox.2021.101905
  2. Clavé, G.; Vasseur, J.-J.; Smietana, M. The Sulfo-Click Reaction and Dual Labeling of Nucleosides. Current Protocols in Nucleic Acid Chemistry, 2020, 83(1), e120. doi: 10.1002/cpnc.120
  3. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261
  4. Cui, X.-Y.; Sun, N.-N.; Xie, X.-N.; Sun, W.-C.; Zhao, Q.; Liu, N. Detection of Newly Synthesized Proteins via Metabolic Incorporation of Non-natural Amino Acid. Chinese Journal of Analytical Chemistry, 2018, 46(11), 1808–1813. doi: 10.1016/s1872-2040(18)61125-9

Alkyne maleimide

Alkyne maleimide,炔烃马来酰亚胺是一种双功能接头试剂，可将末端炔烃连接到各种含硫醇分子，例如含有半胱氨酸残基的蛋白质。 然后可以通过铜催化的点击化学反应将炔烃部分与各种叠氮化物缀合。

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Alkyne maleimide

标签：Maleimides, Alkynes,Click chemistry
货号 规格 价格 货期
41780 25 mg 95.00$ in stock
51780 50 mg 195.00$ in stock
61780 100 mg 290.00$ in stock

Alkyne maleimide is a bifunctional linker reagent which allows to attach terminal alkyne to various thiol-containing molecules, such as proteins containing cysteine residues. The alkyne moiety can be then conjugated with various azides via copper-catalyzed Click chemistry reaction.

炔烃马来酰亚胺是一种双功能接头试剂，可将末端炔烃连接到各种含硫醇分子，例如含有半胱氨酸残基的蛋白质。 然后可以通过铜催化的点击化学反应将炔烃部分与各种叠氮化物缀合。

Alkyne maleimide相关产品

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cy7.5的胺反应性NHS酯。

Protein labeling buffer (with THPTA), 1.5x

Catalytic buffer for Click chemistry modification of proteins.

用于蛋白质点击化学修饰的催化缓冲液。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素（一种众所周知的亲和探针）进行点击化学标记的试剂。

General properties

Appearance: colorless solid 无色固体
Mass spec M+ increment: 234.1
Molecular weight: 234.25
Molecular formula: C12H14N2O3
Solubility: good in DMSO, DMF, alcohols, limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2

Alkyne hydrazide

Alkyne hydrazide,炔烃酰肼双功能接头试剂是一种衔接分子，可用于将末端炔基连接到醛和酮的羰基上。 在遭受氧化应激的蛋白质中会遇到羰基。 许多小的天然分子也是羰基化合物。 大多数糖类以及 RNA 都含有 1,2-二醇片段，这些片段可以被高碘酸盐氧化成醛类，醛类又与酰肼反应。

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Alkyne hydrazide

标签：Alkynes, Hydrazides,Click chemistry
货号 规格 价格 货期
41770 25 mg 95.00$ in stock
51770 50 mg 195.00$ in stock
61770 100 mg 290.00$ in stock

Alkyne hydrazide bifunctional linker reagent is an adapter molecule which is useful to attach terminal alkyne group to a carbonyl group of aldehydes and ketones. Carbonyl groups are encountered in proteins subjected to oxidative stress. Many small natural molecules are also carbonyl compounds. Most saccharides, as well as RNAs contain 1,2-diol fragments which can be oxidized with periodate to aldehydes, which in turn react with hydrazides.

炔烃酰肼双功能接头试剂是一种衔接分子，可用于将末端炔基连接到醛和酮的羰基上。 在遭受氧化应激的蛋白质中会遇到羰基。 许多小的天然分子也是羰基化合物。 大多数糖类以及 RNA 都含有 1,2-二醇片段，这些片段可以被高碘酸盐氧化成醛类，醛类又与酰肼反应。

Alkyne hydrazide相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性花青5琥珀酰亚胺酯。

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃，纯 6 异构体。

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling

用于蛋白质标记的 Cy2 NHS 酯最小染料

General properties

Appearance: colorless solid 无色固体
Mass spec M+ increment: 108.1
Molecular weight: 162.62
Molecular formula: C6H11ClN2O
Solubility: good in water, DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications