标签： CD80 Human

CD80 Molecule, CD80 Antigen , B-Lymphocyte Activation Antigen B7, CTLA-4 Counter-Receptor B7.1, Activation B7-1 Antigen, CD28LG1, CD28LG, LAB7, BB1, B7, Costimulatory Molecule Variant IgV-CD80, T-Lymphocyte Activation Antigen CD80, Costimulatory Factor CD80, CD80 Antigen, B7-1, B7.1.

CD80 which is a member of cell surface immunoglobulin superfamily takes part in the costimulatory signal essential for T-lymphocyte activation. CD80 binds to either human or mouse CD28 and CTLA-4 – binding to CD28 induces T-cell proliferation and cytokine production while binding to CTLA-4 inhibits T-cell activation. CD80 is expressed on activated B cells, activated T cells, and macrophages.

CD80 是细胞表面免疫球蛋白超家族的成员，参与 T 淋巴细胞活化所必需的共刺激信号。 CD80 与人类或小鼠 CD28 和 CTLA-4 结合——与 CD28 结合可诱导 T 细胞增殖和细胞因子产生，而与 CTLA-4 结合可抑制 T 细胞活化。 CD80 在活化的 B 细胞、活化的 T 细胞和巨噬细胞上表达。

CD80 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 216 amino acids and having a molecular mass of 24.9kDa .
CD80 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 昆虫细胞中产生的 CD80 Human Recombinant 是单条糖基化多肽链，含有 216 个氨基酸，分子量为 24.9kDa。
CD80 在 C 末端用 8 个氨基酸 His 标签表达，并通过专有色谱技术进行纯化。

Sf9, Insect cells.

Greater than 95.0% as determined by -PAGE.

CD80 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKD AFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSF MCLIKYGHLR VNQTFNWNTT KQEHFPDNLE HHHHHH.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.