标签： CD80 小鼠重组PRO-2326

ProSpec,CD80 Mouse,CD80 小鼠重组PRO-2326

ProSpec,CD80 Mouse,CD80 小鼠重组PRO-2326,由于与 T 细胞的 CD28 和 CTLA4 配体结合，B 淋巴细胞活化抗原 B7-1 为 T 淋巴细胞提供调节信号 CD-80 参与 T 淋巴细胞活化所必需的共刺激信号。

  • CD80 Mouse

  • CD80 Mouse Recombinant
  • PRO-2326

Catalogue number

PRO-2326

Synonyms

LAB7, CD28LG, CD28LG1, CD28LG1, B71.

Introduction

The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells CD-80 is involved in the costimulatory signal essential for t- lymphocyte activation. t-cell proliferation and cytokine production is induced by the binding of cd28 or ctla-4 to this receptor.
由于与 T 细胞的 CD28 和 CTLA4 配体结合，B 淋巴细胞活化抗原 B7-1 为 T 淋巴细胞提供调节信号 CD-80 参与 T 淋巴细胞活化所必需的共刺激信号。 cd28 或 ctla-4 与该受体结合可诱导 t 细胞增殖和细胞因子产生。

Description

CD80 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 216 amino acids and having a molecular mass of 24.7kDa . CD80 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 CD80 是单条糖基化多肽链，含有 216 个氨基酸，分子量为 24.7kDa。 CD80 在 C 末端用 6 个氨基酸的 His 标签表达，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD80 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.

For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

DVDEQLSKSV KDKVLLPCRY NSPHEDESED RIYWQKHDKV VLSVIAGKLK VWPEYKNRTL YDNTTYSLII LGLVLSDRGT YSCVVQKKER GTYEVKHLAL VKLSIKADFS TPNITESGNP SADTKRITCF ASGGFPKPRF SWLENGRELP GINTTISQDP ESELYTISSQ LDFNTTRNHT IKCLIKYGDA HVSEDFTWEK PPEDPPDSKN HHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

  • CD80 Antibody