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CD79A Human
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CD79A Human Recombinant
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PRO-2468
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Catalogue number
PRO-2468
Synonyms
CD79a Molecule, Membrane-Bound Immunoglobulin-Associated Protein, CD79A Antigen , CD79a Molecule, Immunoglobulin-Associated Alpha, Surface IgM-Associated Protein, MB-1 Membrane Glycoprotein, Ig-Alpha, IGA, B-Cell Antigen Receptor Complex-Associated Protein Alpha Chain, CD79a Antigen, MB-1, MB1.
CD79a 分子、膜结合免疫球蛋白相关蛋白、CD79A 抗原、CD79a 分子、免疫球蛋白相关 α、表面 IgM 相关蛋白、MB-1 膜糖蛋白、Ig-α、IGA、B 细胞抗原受体复合物相关蛋白 α 链,CD79a 抗原,MB-1,MB1。
Introduction
CD79A is a signal-transducing part of the B-cell receptor which plays various roles in B cell development and function. CD79A is also needed for BCR surface expression and for efficient differentiation of pro-B and pre-B-cells. CD79A plays an important role in the tumor promoting effects of myeloid cells, and is a novel target for cancer therapy.
CD79A 是 B 细胞受体的信号转导部分,在 B 细胞发育和功能中发挥各种作用。 BCR 表面表达和前 B 细胞和前 B 细胞的有效分化也需要 CD79A。 CD79A在骨髓细胞的促肿瘤作用中起重要作用,是癌症治疗的新靶点。
Description
CD79A Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 119 amino acids and having a molecular mass of 13.6kDa .
CD79A is expressed with a 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Insect cells.
Purity
Greater than 95.0% as determined by -PAGE.
Formulation
CD79A protein solution contains Phosphate Buffered Saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Amino acid sequence
LWMHKVPASL MVSLGEDAHF QCPHNSSNNA NVTWWRVLHG NYTWPPEFLG PGEDPNGTLI IQNVNKSHGG IYVCRVQEGN ESYQQSCGTY LRVRQPPPRP FLDMGEGTKN RLEHHHHHH.