标签： CD5人重组PRO-1939

CD5 Molecule, CD5, LEU1, CD5 Antigen , Lymphocyte Antigen T1/Leu-1, T1, T-Cell Surface Glycoprotein CD5, CD5 Antigen.

CD5 is a suitable immunohistochemical marker for T-cells, though not as sensitive as CD3. Approximately 76% of T-cell neoplasms are reported to express CD5, and it is also observed in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. CD5 is commonly lost in cutaneous T-cell lymphoma, and its deficiency can be used as an indicator of malignancy in this condition. CD5’s absence in T cell acute lymphoblastic leukemia, though relatively rare, is linked with a poor prognosis. CD5 serves as a receptor in regulating T-cell proliferation.

CD5 是一种合适的 T 细胞免疫组织化学标记物，但不如 CD3 敏感。 据报道，大约 76% 的 T 细胞肿瘤表达 CD5，并且在慢性淋巴细胞白血病、毛细胞白血病和套细胞淋巴瘤细胞中也观察到。 CD5 通常在皮肤 T 细胞淋巴瘤中丢失，其缺乏可作为这种情况下恶性肿瘤的指标。 CD5 在 T 细胞急性淋巴细胞白血病中的缺失虽然相对罕见，但与预后不良有关。 CD5 作为调节 T 细胞增殖的受体。

CD5 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 371 amino acids and having a molecular mass of 41.0 kDa.
CD5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

E.coli.

Sterile Filtered colorless solution.

The CD5 solution contains 20mM Tris-HCl buffer , 10% glycerol and 0.4M Urea.

Greater than 80% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSRLSWYDP DFQARLTRSN SKCQGQLEVY LKDGWHMVCS QSWGRSSKQW EDPSQASKVC QRLNCGVPLS LGPFLVTYTP QSSIICYGQL GSFSNCSHSR NDMCHSLGLT CLEPQKTTPP TTRPPPTTTP EPTAPPRLQL VAQSGGQHCA GVVEFYSGSL GGTISYEAQD KTQDLENFLC NNLQCGSFLK HLPETEAGRA QDPGEPREHQ PLPIQWKIQN SSCTSLEHCF RKIKPQKSGR VLALLCSGFQ PKVQSRLVGG SSICEGTVEV RQGAQWAALC DSSSARSSLR WEEVCREQQC GSVNSYRVLD AGDPTSRGLF CPHQKLSQCH ELWERNSYCK KVFVTCQDPN P.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.