标签： CD3G人重组PRO-2412

ProSpec PRO-2412,CD3G Human,CD3G人重组PRO-2412

ProSpec PRO-2412,CD3G Human,CD3G人重组PRO-2412,CD3-γ多肽由CD3 Gamma编码，CD3 Gamma与CD3-ε、-δ和-zeta以及T细胞受体α/β和γ/δ异二聚体一起构成T细胞受体-CD3复合物。 T 细胞受体-CD3 复合物参与将抗原识别与许多细胞内信号转导途径偶联

  • CD3G Human

  • CD3G Human Recombinant
  • PRO-2412

Catalogue number

PRO-2412

Synonyms

T-cell surface glycoprotein CD3 gamma chain, CD3-GAMMA, T3G, CD3G

Introduction

CD3-gamma polypeptide is encoded by CD3 Gamma which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, configures the T-cell receptor-CD3 complex. The T-cell receptor-CD3 complex takes part in coupling antigen recognition to numerous intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Deficiencies in this gene are associated with T cell immunodeficiency.
CD3-γ多肽由CD3 Gamma编码，CD3 Gamma与CD3-ε、-δ和-zeta以及T细胞受体α/β和γ/δ异二聚体一起构成T细胞受体-CD3复合物。 T 细胞受体-CD3 复合物参与将抗原识别与许多细胞内信号转导途径偶联。 编码ε、γ和δ多肽的基因位于11号染色体上的同一簇中。该基因的缺陷与T细胞免疫缺陷有关。

Description

CD3G Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 103 amino acids and having a molecular mass of 11.8kDa .
CD3G is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Insect cells.

Physical Appearance

Sterile Filtered clear solution.

Formulation

CD3G protein solution contains phosphate buffered saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

ADPQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATISHHH HHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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