标签： CD274 Human

CD274 molecule, CD274 antigen, programmed cell death 1 ligand 1, PD-L1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, B7 homolog 1, B7H1.

CD274 takes part in the costimulatory signal, vital for T-cell proliferation and creation of IL10 and IFNG, in a PDCD1-independent and an IL2-dependent manner. CD274 collaboration with PDCD1 inhibits cytokine production and T-cell proliferation.

CD274 以不依赖 PDCD1 和依赖 IL2 的方式参与共刺激信号，这对 T 细胞增殖和 IL10 和 IFNG 的产生至关重要。 CD274 与 PDCD1 协作抑制细胞因子产生和 T 细胞增殖。

CD274 Human Recombinant produced in E. coli is a single polypeptide chain containing 245 amino acids and having a molecular mass of 27.9kDa .
CD274 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 CD274 Human Recombinant 是单条多肽链，含有 245 个氨基酸，分子量为 27.9kDa。
CD274 在 N 末端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

E.coli.

Sterile Filtered colorless solution.

The CD274 solution contains 20mM Tris-HCl buffer , 1mM DTT and 10% glycerol.

Greater than 90% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSHMFTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEED LKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILV VDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRR LDPEENHTAE LVIPELPLAH PPNER.

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