标签： CD247 人重组PRO-1335

T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD247, CD3Z, T3Z, TCRZ, CD3H, CD3Q, CD3-ZETA.

T-cell surface glycoprotein CD3 zeta chain is a member of the CD3Z/FCER1G family. CD247 is T-cell receptor zeta, which along with T-cell receptor alpha/beta and gamma/delta heterodimers, and also with CD3-gamma, -delta and -epsilon, creates the T-cell receptor-CD3 complex. The zeta chain has a central role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the CD247 antigen causes impaired immune response.

T 细胞表面糖蛋白 CD3 zeta 链是 CD3Z/FCER1G 家族的成员。 CD247 是 T 细胞受体 zeta，它与 T 细胞受体 α/β 和 γ/δ 异二聚体以及 CD3-γ、-δ 和 -epsilon 一起产生 T 细胞受体-CD3 复合物。 zeta 链在将抗原识别与几种细胞内信号转导途径偶联方面具有核心作用。 CD247 抗原的低表达导致免疫反应受损。

CD247 Human Recombinant produced in E. coli is a single polypeptide chain containing 136 amino acids and having a molecular mass of 15.4kDa.
CD247 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

E.coli.

Sterile Filtered colorless solution.

The CD247 solution contains 20mM Tris-HCl buffer , 0.15M NaCl, 10% glycerol and 1mM DTT.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 90% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSRVKFSRS ADAPAYQQGQ NQLYNELNLG RREEYDVLDK RRGRDPEMGG KPQRRKNPQE GLYNELQKDK MAEAYSEIGM KGERRRGKGH DGLYQGLSTA TKDTYDALHM QALPPR.

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