ProSpec-CD244 Human Sf9,CD244 人重组体Sf9 PRO-2413

在 Sf9 昆虫细胞中产生的 CD244 Human Recombinant 是单条糖基化多肽链,包含 448 个氨基酸,分子量为 50.2kDa。ProSpec-CD244 Human Sf9,CD244 人重组体Sf9 PRO-2413

  • CD244 Human, Sf9

  • CD244 Human Recombinant, Sf9
  • PRO-2413

Catalogue number

PRO-2413

Synonyms

Natural killer cell receptor 2B4, NK cell activation-inducing ligand, NAIL, NK cell type I receptor protein 2B4, NKR2B4, h2B4, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4, CD244, 2B4.

Introduction

Cluster of Differentiation 244 contains 2 Ig-like domains. CD244 is a cell surface receptor expressed on natural killer cells which mediate non-major histocompatibility complex restricted killing. NK-cell and target cells interaction via the CD244 receptor is believed to modulate NK-cell cytolytic activity. CD244 molecules function in eosinophil adhesion and chemotaxis, and have a role in the pathophysiology of allergic rhinitis .

分化簇244包含2个Ig样结构域。 CD244 是一种在自然杀伤细胞上表达的细胞表面受体,可介导非主要组织相容性复合物限制性杀伤。 NK 细胞和靶细胞通过 CD244 受体的相互作用被认为可以调节 NK 细胞的溶细胞活性。 CD244分子在嗜酸性粒细胞粘附和趋化中起作用,并且在变应性鼻炎的病理生理学中起作用。

Description

CD244 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 448 amino acids and having a molecular mass of 50.2kDa . CD244 is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 昆虫细胞中产生的 CD244 Human Recombinant 是单条糖基化多肽链,包含 448 个氨基酸,分子量为 50.2kDa。 CD244 在 C 末端用 239 个氨基酸的 hIgG-His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Insect cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD244 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

ADLGKGCQGS ADHVVSISGV PLQLQPNSIQ TKVDSIAWKK LLPSQNGFHH ILKWENGSLP SNTSNDRFSF IVKNLSLLIK AAQQQDSGLY CLEVTSISGK VQTATFQVFV FDKVEKPRLQ GQGKILDRGR CQVALSCLVS RDGNVSYAWY RGSKLIQTAG NLTYLDEEVD INGTHTYTCN VSNPVSWESH TLNLTQDCQN AHQEFRFWPL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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  • CD244 Human