- Description
Catalogue number
PRO-2371
Synonyms
CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, CD226 Molecule, CD226 Antigen, DNAX Accessory Molecule 1, DNAM-1, DNAM1, T Lineage-Specific Activation Antigen 1 Antigen, Platelet And T Cell Activation Antigen 1, DNAX Accessory Molecule-1, Adhesion Glycoprotein, TLiSA1, PTA1.
Introduction
CD226 belongs to the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 is a 65kDa glycoprotein expressed on the surface NK cells, platelets, monocytes and a subset of T cells. CD226 facilitates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. CD226 also plays a role in megakaryocytic cell maturation.
CD226 属于 Ig 超家族，包含 V 组的 2 个 Ig 样结构域。 CD226 是一种 65kDa 糖蛋白，在 NK 细胞、血小板、单核细胞和 T 细胞亚群表面表达。 CD226 促进血小板和巨核细胞与血管内皮细胞的细胞粘附。 CD226 还在巨核细胞成熟中起作用。
Description
CD226 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 471 amino acids and having a molecular mass of 53.2kDa .
CD226 is fused to a 239 amino acid hIgG-His-tag at C-terminus & purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 CD226 Human Recombinant 是单条糖基化多肽链，包含 471 个氨基酸，分子量为 53.2kDa。
CD226 在 C 末端与 239 个氨基酸的 hIgG-His-tag 融合，并通过专有色谱技术进行纯化。
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CD226 protein solution containing Phosphate Buffered Saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by -PAGE.
Amino acid sequence
ADPEEVLWHT SVPFAENMSL ECVYPSMGIL TQVEWFKIGT QQDSIAIFSP THGMVIRKPY AERVYFLNST MASNNMTLFF RNASEDDVGY YSCSLYTYPQ GTWQKVIQVV QFEAAVP SNSHIVSEPG KNVTLTCQPQ MTWPVQAVRW EKIQPRQIDL LTYCNLVHGR NFTSKFPRQI VSNCSHGRWS VIVIPDVTVS DSGLYRCYLQ ASAGENETFV MRLTVAEGKT DNLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
-
CD226 Human