ProSpec,FCGR3B Human,CD16b 人重组PRO-2486

ProSpec,FCGR3B Human,CD16b 人重组PRO-2486,在 Sf9 杆状病毒细胞中产生的 FCGR3B 是单条糖基化多肽链,包含 188 个氨基酸,分子量为 21.4kDa。

  • FCGR3B Human

  • CD16b Human Recombinant
  • PRO-2486

Catalogue number

PRO-2486

Synonyms

Fc Fragment Of IgG Receptor IIIb, Fc Fragment Of IgG, Low Affinity IIIb, Receptor , Fc Gamma Receptor IIIb, IgG Fc Receptor III-1, Fc-Gamma RIII-Beta, Fc-Gamma RIIIb, FCRIIIb, FCR-10, FCRIII, FCGR3, CD16b, FCG3, Fc Fragment Of IgG, Low Affinity IIIb, Receptor For , Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B, Fc-Gamma Receptor IIIb , Fc-Gamma RIII, CD16b Antigen, IGFR3, CD16.

IgG受体IIIb的Fc片段,IgG的Fc片段,低亲和力IIIb,受体,Fcγ受体IIIb,IgG Fc受体III-1,Fc-γRIII-β,Fc-γRIIIb,FCRIIIb,FCR-10,FCRIII, FCGR3、CD16b、FCG3、IgG 的 Fc 片段、低亲和力 IIIb、受体 For 、低亲和力免疫球蛋白 γ Fc 区受体 III-B、Fc-γ 受体 IIIb、Fc-γ RIII、CD16b 抗原、IGFR3、CD16。

Introduction

FCGR3B, also known as CD16b belongs to the Ig super family. FCGR3B encodes a glycosylphosphatidylinositol -anchored protein which is expressed constitutively by neutrophils. FCGR3B binds to complex or aggregated IgG and monomeric IgG. Different from III-A, FCGR3B cannot arbitrate antibody-dependent cytotoxicity and phagocytosis. FCGR3B operate to capture immune complexes in peripheral blood circulation that does not activate neutrophils.

FCGR3B,也称为CD16b,属于Ig超家族。 FCGR3B 编码由中性粒细胞组成型表达的糖基磷脂酰肌醇锚定蛋白。 FCGR3B 与复杂或聚集的 IgG 和单体 IgG 结合。 与 III-A 不同,FCGR3B 不能仲裁抗体依赖性细胞毒性和吞噬作用。 FCGR3B 用于捕获外周血循环中不激活中性粒细胞的免疫复合物。

Description

FCGR3B produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 188 amino acids and having a molecular mass of 21.4kDa. .
FCGR3B is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 FCGR3B 是单条糖基化多肽链,包含 188 个氨基酸,分子量为 21.4kDa。 .
FCGR3B 在 C 末端用 8 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

FCGR3B protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

EDLPKAVVFL EPQWYSVLEK DSVTLKCQGA YSPEDNSTQW FHNENLISSQ ASSYFIDAAT VNDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKDRKY FHHNSDFHIP KATLKDSGSY FCRGLVGSKN VSSETVNITI TQGLAVSTIS VEHHHHHH.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.