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FCGR3B Human
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CD16b Human Recombinant
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PRO-2486
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Catalogue number
PRO-2486
Synonyms
Fc Fragment Of IgG Receptor IIIb, Fc Fragment Of IgG, Low Affinity IIIb, Receptor , Fc Gamma Receptor IIIb, IgG Fc Receptor III-1, Fc-Gamma RIII-Beta, Fc-Gamma RIIIb, FCRIIIb, FCR-10, FCRIII, FCGR3, CD16b, FCG3, Fc Fragment Of IgG, Low Affinity IIIb, Receptor For , Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B, Fc-Gamma Receptor IIIb , Fc-Gamma RIII, CD16b Antigen, IGFR3, CD16.
IgG受体IIIb的Fc片段,IgG的Fc片段,低亲和力IIIb,受体,Fcγ受体IIIb,IgG Fc受体III-1,Fc-γRIII-β,Fc-γRIIIb,FCRIIIb,FCR-10,FCRIII, FCGR3、CD16b、FCG3、IgG 的 Fc 片段、低亲和力 IIIb、受体 For 、低亲和力免疫球蛋白 γ Fc 区受体 III-B、Fc-γ 受体 IIIb、Fc-γ RIII、CD16b 抗原、IGFR3、CD16。
Introduction
FCGR3B, also known as CD16b belongs to the Ig super family. FCGR3B encodes a glycosylphosphatidylinositol -anchored protein which is expressed constitutively by neutrophils. FCGR3B binds to complex or aggregated IgG and monomeric IgG. Different from III-A, FCGR3B cannot arbitrate antibody-dependent cytotoxicity and phagocytosis. FCGR3B operate to capture immune complexes in peripheral blood circulation that does not activate neutrophils.
FCGR3B,也称为CD16b,属于Ig超家族。 FCGR3B 编码由中性粒细胞组成型表达的糖基磷脂酰肌醇锚定蛋白。 FCGR3B 与复杂或聚集的 IgG 和单体 IgG 结合。 与 III-A 不同,FCGR3B 不能仲裁抗体依赖性细胞毒性和吞噬作用。 FCGR3B 用于捕获外周血循环中不激活中性粒细胞的免疫复合物。
Description
FCGR3B produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 188 amino acids and having a molecular mass of 21.4kDa. .
FCGR3B is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 FCGR3B 是单条糖基化多肽链,包含 188 个氨基酸,分子量为 21.4kDa。 .
FCGR3B 在 C 末端用 8 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。
Source
Physical Appearance
Formulation
FCGR3B protein solution contains Phosphate Buffered Saline and 10% glycerol.
Stability
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by -PAGE.
Amino acid sequence
EDLPKAVVFL EPQWYSVLEK DSVTLKCQGA YSPEDNSTQW FHNENLISSQ ASSYFIDAAT VNDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKDRKY FHHNSDFHIP KATLKDSGSY FCRGLVGSKN VSSETVNITI TQGLAVSTIS VEHHHHHH.