PACE4是控制细胞分化和形态发生的加工蛋白酶家族的成员。日本德岛大学Akihiko Tsujij教授的研究小组已经阐明了它的结构和功能。PACE4被认为在器官发生等发育和分化过程中起着特别重要的作用。近年来,有研究认为它参与了癌症转移和基质金属蛋白酶的激活。
Cosmo Bio抗体,Anti Proprotein Convertase Subtilisin/Kexin Type 6 (PACE4) – HomoB domain pAb (Rabbit, Antiserum),CAC-SK-T01-001
Application: WB, IHC, IP
Clonality: Polyclonal
Host: Rabbit
Purification: Serum
Reactivity: Human
PACE4 is a member of the processing protease family that controls cell differentiation and morphogenesis. Its structure and function have been elucidated by Professor Akihiko Tsujij’s research group at Tokushima University. PACE4 is believed to play a particularly important role in development and differentiation processes such as organogenesis. In recent years, it has been suggested that it is involved in cancer metastasis and activation of matrix metalloproteinases.