γ -微管蛋白是微管蛋白家族中一个普遍存在且高度保守的亚家族。这种蛋白质存在于微管组织中心,如纺锤极或中心体。当微管被解聚时,它仍然与中心体相关,这表明它是微管组装负端成核的重要组成部分。因此,γ -小管蛋白可以用作中心体制造者。
Cosmo Bio抗体,Anti Tubulin Gamma-1 Chain (GCP-1) mAb (Clone E39),CAC-NM-MA-003
Application: ICC, ELISA, WB, IF
Clonality: Monoclonal
Host: Mouse
Purification: Ammonium Sulfate
Reactivity: Human, Mouse, Rat
Gamma-tubulins constitute a ubiquitous and highly conserved subfamily of the tubulin family. The protein is found at microtubule-organizing centers, such as spindle poles or centrosomes. It remains associated with centrosomes when microtubules are depolymerized, suggesting that it is an integral component that may play a role in minus-end nucleation of microtubule assembly. Thus, gamma-tubulins can be used as a centrosome maker.