Cosmo Bio抗体,Anti N(Omega)-(Carboxymethyl) Arginine (CMA) mAb (Clone 3F5),CAC-AGE-M04
Application: ELISA, IHC, WB
Clonality: Monoclonal
Host: Mouse
Purification: Ig-PG
Background
晚期糖基化终产物(AGE)是还原糖和蛋白质之间的非酶糖基化反应(米勒德反应)后期产生的结构的总称。众所周知，年龄积累在与年龄相关的疾病如糖尿病和动脉硬化中显著增加。
Advanced Glycation End Product (AGE) is a general term for structures generated in the late stage of non-enzymatic glycation reactions (Millard reactions) between reducing sugars and proteins. AGE accumulation is known to be significantly elevated in age-related diseases such as diabetes and arteriosclerosis.
Nω-(carboxymethyl) arginine (CMA), a CML analogue, is an acid-labile AGE structure which was discovered in enzymatic hydrolysate of glycated collagen. CMA is preferentially generated in glycated collagen.
Application
Western blotting, 1/100 to 1/200
Immunohistochemistry (frozen sections), 1/50 to 1/100
ELISA, 1/100 to 1/200