标签： Azides

JOE azide, 5- isomer,JOE 叠氮化物，5- isomer

JOE azide, 5- isomer,JOE 叠氮化物，5- isomer,JOE 是一种荧光染料，在光谱的黄色区域发射。 荧光团与另一种氯化荧光素 HEX 染料的通道相匹配。JOE染料常用于qPCR； 使用点击化学可以实现寡核苷酸标记。 这是 JOE 的叠氮化物衍生物，用于 Click 化学，纯 5-异构体。

  • Products
  • Reactive dyes
  • Dye azides
  • JOE azide, 5- isomer

JOE azide, 5- isomer

标签：Azides, JOE,5- isomer
货号 规格 价格 货期
31130 500 uL, 10 mM/DMSO please inquire 10 days
A1130 1 mg 110.00$ in stock
B1130 5 mg 210.00$ in stock
C1130 10 mg 310.00$ in stock
D1130 25 mg 410.00$ in stock
E1130 50 mg 695.00$ in stock
F1130 100 mg 1190.00$ in stock

JOE is a fluorescent dye with the emission in yellow region of the spectrum. The fluorophore matches channel of HEX dye, another chlorinated fluorescein.

JOE dye is often used in qPCR; oligo labeling can be achieved using Click chemistry. This is an azide derivative of JOE for Click chemistry, pure 5-isomer.

JOE 是一种荧光染料，在光谱的黄色区域发射。 荧光团与另一种氯化荧光素 HEX 染料的通道相匹配。

JOE染料常用于qPCR； 使用点击化学可以实现寡核苷酸标记。 这是 JOE 的叠氮化物衍生物，用于 Click 化学，纯 5-异构体。

Absorption and emission spectra of JOE dye

JOE azide, 5- isomer

JOE azide, 5- isomer,JOE 叠氮化物，5- isomer相关产品

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

Alkyne dT phosphoramidite

Phosphoramidite modifier for the synthesis of oligonucleotides containing alkyne modification in the middle of the chain.

亚磷酰胺修饰剂，用于合成在链中间含有炔烃修饰的寡核苷酸。

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

General properties

Appearance: red solid 红色固体
Mass spec M+ increment: 586.1
Molecular weight: 587.37
CAS number: 1422178-11-7
Molecular formula: C26H20N4Cl2O8
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 533
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 554
Fluorescence quantum yield: 0.61
CF260: 0.36
CF280: 0.28

相关文献：

  1. Taskova, M.; Astakhova, K. Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids. Bioconjugate Chemistry, 2019, 30(12), 3007–3012. doi: 10.1021/acs.bioconjchem.9b00746
  2. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145

HEX azide, 6-isomer,HEX 叠氮化物 6-isomer

HEX azide, 6-isomer,HEX 叠氮化物 6-isomer,六氯荧光素 (HEX) 是荧光染料荧光素的六氯化衍生物。 HEX 标记的寡核苷酸用于 PCR，HEX 通道广泛用于多重 qPCR。使用 HEX 叠氮化物和含炔烃的寡核苷酸通过叠氮化物-炔烃环加成，可以轻松生成带有 HEX 标记的寡核苷酸。

  • Products
  • Reactive dyes
  • Dye azides
  • HEX azide, 6-isomer

HEX azide, 6-isomer

标签：Azides, HEX (Hexachlorofluorescein)
货号 规格 价格 货期
AB230 1 mg 110.00$ in stock
BB230 5 mg 210.00$ in stock
CB230 10 mg 310.00$ in stock
DB230 25 mg 410.00$ in stock
EB230 50 mg 695.00$ in stock
FB230 100 mg 1190.00$ in stock

Hexachlorofluorescein (HEX) is a hexachlorinated derivate of the fluorescent dye fluorescein. HEX-labeled oligonucleotides are used in PCR and the HEX channel is widely used in multiplex qPCR.

Oligonucleotides with a HEX label can be easily generated using HEX azide and alkyne-containing oligonucleotide via azide-alkyne cycloaddition.

HEX exhibits an excitation peak at 533 nm and an emission peak at 549 in green-yellow area, and it can serve as a substitute for JOE, BODIPY™ 530/550, VIC™ because of the similar spectral characteristics.

六氯荧光素 (HEX) 是荧光染料荧光素的六氯化衍生物。 HEX 标记的寡核苷酸用于 PCR，HEX 通道广泛用于多重 qPCR。

使用 HEX 叠氮化物和含炔烃的寡核苷酸通过叠氮化物-炔烃环加成，可以轻松生成带有 HEX 标记的寡核苷酸。

HEX 在绿黄色区域呈现 533 nm 处的激发峰和 549 处的发射峰，由于具有相似的光谱特性，它可以作为 JOE、BODIPY™ 530/550、VIC™ 的替代品。

Absorption and emission spectra of HEX

HEX azide, 6-isomer

HEX azide, 6-isomer,HEX 叠氮化物 6-isomer相关产品

Sulfo-Cyanine5 carboxylic acid

Water-soluble Cyanine5 carboxylic acid, non-activated fluorescent dye.

水溶性Cyanine5羧酸，非活化荧光染料。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cyanine3 荧光染料的叠氮化物衍生物。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cy5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

General properties

Appearance: orange solid  橙色固体
Mass spec M+ increment: 661.9
Molecular weight: 665.09
CAS number: 1450752-91-6
Molecular formula: C24H12N4Cl6O6
IUPAC name: N-(3-azidopropyl)-2′,4,4′,5′,7,7′-hexachloro-3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-6-carboxamide
Solubility: very soluble in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 533
ε, L⋅mol−1⋅cm−1: 87770
Emission maximum, nm: 549
Fluorescence quantum yield: 0.57
CF260: 0.30
CF280: 0.13
BODIPY™, VIC™ are trademarks of Thermo Fisher Scientific.

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer,FAM（荧光素）叠氮化物。 固体和 10 mM DMSO 溶液，用于点击化学的标记试剂。

  • Products
  • Reactive dyes
  • Dye azides
  • FAM azide, 6-isomer

FAM azide, 6-isomer

标签：FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
15130 100 uL, 10 mM/DMSO 80.00$ in stock
35130 500 uL, 10 mM/DMSO 100.00$ in stock
45130 1 mL, 10 mM/DMSO 150.00$ in stock
A5130 1 mg 80.00$ in stock
B5130 5 mg 100.00$ in stock
C5130 10 mg 150.00$ in stock
D5130 25 mg 295.00$ 5 days
E5130 50 mg 450.00$ in stock
F5130 100 mg 780.00$ in stock

FAM (fluorescein) azide. solid and 10 mM solution in DMSO, labeling reagent for Click chemistry.

Pure 6-isomer.

Can replace DyLight 488.

FAM（荧光素）叠氮化物。 固体和 10 mM DMSO 溶液，用于点击化学的标记试剂。

纯 6 异构体。

可替代 DyLight 488。

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer相关产品

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.

炔烃 NHS 酯，用于标记具有炔烃基团的生物分子，用于铜催化的点击化学。

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 1386385-76-7
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献：

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Lee, R.; Erstling, J.A.; Hinckley, J.A.; Chapman, D.V.; Wiesner, U.B. Addressing Particle Compositional Heterogeneities in Super-Resolution-Enhanced Live-Cell Ratiometric pH Sensing with Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticles. Advanced Functional Materials, 2021, 31(45), 2106144. doi: 10.1002/adfm.202106144
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Reed, S.A.; Brzovic, D.A.; Takasaki, S.S.; Boyko, K.V.; Antos, J.M. Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag. Bioconjugate Chemistry, 2020, 31(5), 1463–1473. doi: 10.1021/acs.bioconjchem.0c00156

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer,FAM 叠氮化物既可作为固体化合物使用，也可作为 10 mM DMSO 溶液提供，可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

  • Products
  • Reactive dyes
  • Dye azides
  • FAM azide, 5-isomer

FAM azide, 5-isomer

标签：FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
14130 100 uL, 10 mM/DMSO 80.00$ in stock
34130 500 uL, 10 mM/DMSO 100.00$ in stock
44130 1 mL, 10 mM/DMSO 150.00$ in stock
A4130 1 mg 80.00$ in stock
B4130 5 mg 100.00$ in stock
C4130 10 mg 150.00$ in stock
D4130 25 mg 295.00$ in stock
E4130 50 mg 450.00$ in stock
F4130 100 mg 780.00$ in stock

FAM azide for Click chemistry labeling. FAM remains one of the most popular fluorescent labels for various applications. Most instruments capable of fluorescence detection, ranging from plate readers to fluorescence microscopes, are able to work in FAM channel.

With versatility of Click chemistry and this reagent, it is possible to attach this popular fluorophore to nearly any alkyne bearing molecule.

FAM azide is available both as solid compound, and as 10 mM solution in DMSO ready to use in our recommended labeling protocol. This product is a pure 5-isomer. FAM is a replacement for DyLight 488.

用于点击化学标记的 FAM 叠氮化物。 FAM 仍然是各种应用中最受欢迎的荧光标记之一。 大多数能够进行荧光检测的仪器，从读板器到荧光显微镜，都能够在 FAM 通道中工作。

借助 Click 化学和该试剂的多功能性，可以将这种流行的荧光团连接到几乎任何带有炔烃的分子上。

FAM 叠氮化物既可作为固体化合物使用，也可作为 10 mM DMSO 溶液提供，可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer相关产品

BDP TMR NHS ester

Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.

BDP TMR 的胺活性 NHS 酯，用于 TAMRA 通道的明亮硼二吡咯亚甲基染料，特别适用于荧光偏振测定。

HEX azide, 6-isomer

Azide of green-yellow emitting HEX dye is used for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.

绿黄色发射 HEX 染料的叠氮化物用于通过 [3+2]-偶极环加成与寡核苷酸缀合。

BDP TR azide

BDP TR is a red emitting fluorophore for ROX channel. This is an azide for copper catalyzed and copper free Click chemistry conjugation.

BDP TR 是一种用于 ROX 通道的红色发射荧光团。 这是一种用于铜催化和无铜点击化学偶联的叠氮化物。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 510758-23-3
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献：

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Gueiderikh, A.; Maczkowiak-Chartois, F.; Rouvet, G.; Souquère-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F. Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances, 2021, 7(1), eabb5414. doi: 10.1126/sciadv.abb5414
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Kim, D.; Singh, N.; Waldemer-Streyer, R.J.; Yoon, M.-S.; Chen, J. Muscle-derived TRAIL negatively regulates myogenic differentiation. Experimental Cell Research, 2020, 394(1), 112165. doi: 10.1016/j.yexcr.2020.112165

Cyanine7.5 azide,Cy7.5 叠氮化物

Cyanine7.5 azide,Cy7.5 叠氮化物,Cyanine7.5 是一种具有长波红外荧光的 NIR 染料。 该衍生物是 Click Chemistry 的叠氮化物。可用于构建含有 Cyanine7.5、近红外荧光染料和改进的 Cy7.5® 类似物的各种标记生物分子。 当用于体内成像时，这些缀合物可以利用 NIR 组织透明度。 这种荧光团也可用于其他荧光应用，尤其是需要低荧光背景的应用。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine7.5 azide

Cyanine7.5 azide

标签：Cyanine7.5,Cy7.5, Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
46030 1 mL, 10 mM in DMSO 410.00$ in stock
16030 100 uL, 10 mM/DMSO 110.00$ in stock
36030 500 uL, 10 mM/DMSO 210.00$ in stock
A6030 1 mg 110.00$ in stock
B6030 5 mg 210.00$ in stock
C6030 10 mg 310.00$ in stock
D6030 25 mg 410.00$ in stock
E6030 50 mg 695.00$ in stock
F6030 100 mg 1190.00$ in stock

Cyanine7.5 is a NIR dye with long-wave infrared fluorescence. This derivative is azide for Click Chemistry.

Can be used for the construction of various labeled biomolecules containing Cyanine7.5, near infrared fluorescent dye, and an improved analog of Cy7.5®. These conjugates can take advantage of NIR tissue transparency when used for in vivo imaging. This fluorophore is also useful for other fluorescent applications, especially requiring low fluorescent background.

Azide is available as DMSO solution, ready for general Click Chemistry labeling protocol, or in solid form for custom labeling applications.

Structure features rigid bridged polymethyne chain to increase quantum yield by 20%, allowing for brighter signal.

Cyanine7.5 是一种具有长波红外荧光的 NIR 染料。 该衍生物是 Click Chemistry 的叠氮化物。

可用于构建含有 Cyanine7.5、近红外荧光染料和改进的 Cy7.5® 类似物的各种标记生物分子。 当用于体内成像时，这些缀合物可以利用 NIR 组织透明度。 这种荧光团也可用于其他荧光应用，尤其是需要低荧光背景的应用。

叠氮化物以 DMSO 溶液的形式提供，可用于一般的 Click Chemistry 标记方案，或以固体形式用于定制标记应用。

结构具有刚性桥接聚甲炔链，可将量子产率提高 20%，从而获得更亮的信号。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 azide

Cyanine7.5 azide,Cy7.5 叠氮化物相关产品

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

General properties

Appearance: green powder / solution 绿色粉末/溶液
Molecular weight: 767.44
CAS number: 1628790-36-2; 1628897-78-8 (without anion)
Molecular formula: C48H55ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献：

  1. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
  2. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
  3. Pearce, H.A.; Qian, H.; Connell, T.U.; Huang, D.; Gottstein, C.; Donnelly, P.S.; Peter, K.; Gregorevic, P.; Hagemeyer, C.E. Site-specific glycation and chemo-enzymatic antibody sortagging for the retargeting of rAAV6 to inflamed endothelium. Molecular Therapy – Methods & Clinical Development, 2019, 14, 261–269. doi: 10.1016/j.omtm.2019.07.003
  4. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
Cy® is a trademark of GE Healthcare.

Cy7 azide,Cy7 叠氮化物

Cy7 azide,Cy7 叠氮化物,Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物，是 Cy7® 叠氮化物的类似物。该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。环己烷桥接的聚甲炔链允许量子产率增加 20%（与母体非桥接结构相比）。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine7 azide

Cyanine7 azide

标签：Cyanine7,Cy7, Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
15030 100 uL, 10 mM/DMSO 110.00$ in stock
35030 500 uL, 10 mM/DMSO 210.00$ in stock
45030 1 mL, 10 mM/DMSO 410.00$ in stock
A5030 1 mg 110.00$ in stock
B5030 5 mg 210.00$ in stock
C5030 10 mg 310.00$ in stock
D5030 25 mg 410.00$ in stock
E5030 50 mg 695.00$ in stock

Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物，是 Cy7® 叠氮化物的类似物。

该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。

环己烷桥接的聚甲炔链允许量子产率增加 20%（与母体非桥接结构相比）。

Cyanine7 absorbance and emission spectra

Cyanine7 azide

Cy7 azide,Cy7 叠氮化物相关产品

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cy7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  2. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  3. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  4. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
Cy® is a trademark of GE Healthcare.

Cy5.5 azide,Cy5.5 叠氮化物

Cy5.5 azide,Cy5.5 叠氮化物,这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine5.5 azide

Cyanine5.5 azide

标签：Cyanine5.5,Cy5.5, Azides, Microscopy
货号 规格 价格 货期
14030 100 uL, 10 mM/DMSO 110.00$ in stock
34030 500 uL, 10 mM/DMSO 210.00$ in stock
44030 1 mL, 10 mM/DMSO 410.00$ in stock
A4030 1 mg 110.00$ in stock
B4030 5 mg 210.00$ in stock
C4030 10 mg 310.00$ in stock
D4030 25 mg 410.00$ in stock
E4030 50 mg 695.00$ in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 azide

Cy5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cyanine7的胺活性NHS酯。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark blue powder / solution 深蓝色粉末/溶液
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  2. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  3. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  4. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
Cy® is a trademark of Cytiva.

Cy5 azide,Cy5 叠氮化物

Cy5 azide,Cy5 叠氮化物,用于 Click Chemistry 的 Cy5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine5 azide

Cyanine5 azide

标签：Cyanine5, Cy5,Azides, Microscopy
货号 规格 价格 货期
13030 100 uL, 10 mM/DMSO 110.00$ in stock
33030 500 uL, 10 mM/DMSO 210.00$ in stock
43030 1 mL, 10 mM/DMSO 410.00$ in stock
A3030 1 mg 110.00$ in stock
B3030 5 mg 210.00$ in stock
C3030 10 mg 310.00$ in stock
D3030 25 mg 410.00$ in stock
E3030 50 mg 695.00$ in stock
F3030 100 mg 1190.00$ in stock

Cyanine5 azide labeling reagent for Click Chemistry, available as 10 mM solution in DMSO, and in solid form.

This azide is soluble in organic solvents (e.g. DMSO, DMF), therefore the labeling reaction should be carried out with a small amount of an organic co-solvent. This azide can be used for the labeling of alkyne-modified biomolecules in mixtures of water with organic solvents. The solution in DMSO is ready for use in bioconjugation. A water-soluble sulfonated version of this reagent is also available.

Cyanine5 is an analog of Cy5®, one of the most commonly used fluorophores which is compatible with various instruments. Cyanine5 can also be used as a replacement for DyLight® 649.

用于 Click Chemistry 的 Cyanine5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。

这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

Cyanine5 是 Cy5® 的类似物，Cy5® 是最常用的荧光团之一，可与各种仪器兼容。 Cyanine5 也可用作 DyLight® 649 的替代品。

Cyanine5 absorbance and emission spectra

Cyanine5 azide

Cy5 azide,Cy5 叠氮化物相关产品

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

General properties

Appearance: dark blue powder / solution
Molecular weight: 601.22
CAS number: 1267539-32-1 (chloride)
Molecular formula: C35H45ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), very poorly soluble in water (0.63 mM, 110 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  2. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  3. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  4. von Döhren, J.; Kuhl, S. A simple method for long-term vital-staining of ciliated epidermal cells in aquatic larvae. Journal of Biological Methods, 2020, 7(2), e132. doi: 10.14440/jbm.2020.320
Cy® is a trademark of Cytiva.

Cy3.5 azide ,Cy3.5 染料叠氮化物

Cy3.5 azide ,Cy3.5 染料叠氮化物,Cyanine3.5 标记试剂、固体材料和 10 mM DMSO 溶液，用于 Click Chemistry。可替代 Cy3.5®、DyLight 594。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine3.5 azide

Cyanine3.5 azide

标签：Cyanine3.5, Cy3.5,Azides
货号 规格 价格 货期
12030 100 uL, 10 mM/DMSO 110.00$ in stock
32030 500 uL, 10 mM/DMSO 210.00$ in stock
42030 1 mL, 10 mM/DMSO 410.00$ in stock
A2030 1 mg 110.00$ in stock
B2030 5 mg 210.00$ in stock
C2030 10 mg 310.00$ in stock
D2030 25 mg 410.00$ in stock
E2030 50 mg 695.00$ in stock
F2030 100 mg 1190.00$ in stock

Cyanine3.5 labeling reagent, solid material and 10 mM solution in DMSO, for Click Chemistry.

Can replace Cy3.5®, DyLight 594.

Cyanine3.5 标记试剂、固体材料和 10 mM DMSO 溶液，用于 Click Chemistry。

可替代 Cy3.5®、DyLight 594。

Cy3.5 absorbance and emission spectra

Cyanine3.5 azide

Cy3.5 azide ,Cy3.5 染料叠氮化物相关产品

PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP（苯乙炔基芘），用于 Click-Chemistry 标记的多环芳烃荧光染料。

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

General properties

Appearance: dark purple powder / solution 深紫色粉末/溶液
Molecular weight: 675.31
Molecular formula: C41H47N6ClO
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), insoluble in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 591
ε, L⋅mol−1⋅cm−1: 116000
Emission maximum, nm: 604
Fluorescence quantum yield: 0.35
CF260: 0.29
CF280: 0.22

相关文献：

  1. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586
  2. Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046–3055;. doi: 10.1039/c6py00518g
  3. Astakhova, I.K.; Wengel, J. Interfacing Click Chemistry with Automated Oligonucleotide Synthesis for the Preparation of Fluorescent DNA Probes Containing Internal Xanthene and Cyanine Dyes. Chemistry – a European Journal, 2013, 19(3), 1112-1122. doi: 10.1002/chem.201202621
Cy® is a trademark of GE Healthcare.

Cy3 azide,Cy3 叠氮化物

Cy3 azide,Cy3 叠氮化物,用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine3 azide

Cyanine3 azide

标签：Cyanine3, Cy3,Azides, Microscopy
货号 规格 价格 货期
11030 100 uL, 10 mM/DMSO 110.00$ in stock
31030 500 uL, 10 mM/DMSO 210.00$ in stock
41030 1 mL, 10 mM/DMSO 410.00$ in stock
A1030 1 mg 110.00$ in stock
B1030 5 mg 210.00$ in stock
C1030 10 mg 310.00$ in stock
D1030 25 mg 410.00$ in stock
E1030 50 mg 695.00$ in stock
F1030 100 mg 1190.00$ in stock

Cyanine3 dye azide for Click Chemistry, an analog of Cy3® azide. Cy3® is one of the most broadly used fluorophores which can be detected by various fluorometers, imagers, and microscopes. Due to inherently high extinction coefficient, Cyanine3 is also easily detected by naked eye on gels, and in solution. This is non-sulfonated dye which requires organic co-solvent (DMF, DMSO, or other) for efficient labeling in water. Water-soluble version of this reagent is also available.

Product is available both as solid compound, and as 10 mM solution in DMSO which is ready to use in our recommended protocol.

Cyanine3 fluorescent properties are identical to Cy3®, and similar to DyLight 549.

用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

产品既可以作为固体化合物提供，也可以作为 10 mM DMSO 溶液提供，可在我们推荐的方案中使用。

Cyanine3 荧光特性与 Cy3® 相同，与 DyLight 549 相似。

Cy3 absorbance and emission spectra

Cyanine3 azide

Customers also purchased with this product

PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP（苯乙炔基芘），用于 Click-Chemistry 标记的多环芳烃荧光染料。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Cyanine3 azide Add this product to your cart and
get free express delivery

General properties

Appearance: red powder / solution 红粉/溶液
Molecular weight: 575.19
CAS number: 1167421-28-4 (chloride)
Molecular formula: C33H43N6OCl
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (40 mg/L = 60 uM)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  2. Tan, M.S.Y.; Davison, D.; Sanchez, M.I.; Anderson, B.M.; Howell, S.; Snijders, A.; Edgington-Mitchell, L.E.; Deu, E. Novel broad-spectrum activity-based probes to profile malarial cysteine proteases. PLoS One, 2020, 15(1), e0227341. doi: 10.1371/journal.pone.0227341
  3. Saqr, A.; Vakili, M.R.; Huang, Y.-H.; Lai, R.; Lavasanifar, A. Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma. ACS Omega, 2019, 4(20), 18867–18879. doi: 10.1021/acsomega.9b02910
  4. Morimoto, K.; Cole, K.S.; Kourelis, J.; Witt, C.H.; Brown, D.; Krahn, D.; Stegmann, M.; Kaschani, F.; Kaiser, M.; Burton, J.; Mohammed, S.; Yamaguchi-Shinozaki, K.; Weerapana, E.; van der Hoorn, R.A.L. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology, 2019, 180(4), 1848–1859. doi: 10.1104/pp.19.00481
Cy® is a trademark of Cytiva.

Coumarin 343 X azide,Coumarin 343 X 叠氮化物

Coumarin 343 X azide,Coumarin 343 X 叠氮化物,香豆素 343 是一种蓝色荧光团，最大发射波长约为 480 nm。 这种染料与荧光素形成 FRET 对，并可以收集蓝光能量用于随后转移到其他荧光团。

  • Products
  • Reactive dyes
  • Dye azides
  • Coumarin 343 X azide

Coumarin 343 X azide

标签：Azides, Coumarin 343
货号 规格 价格 货期
12630 1 mg 110.00$ in stock
22630 5 mg 210.00$ in stock
42630 25 mg 410.00$ in stock
52630 50 mg 695.00$ in stock
62630 100 mg 1190.00$ in stock
Coumarin 343 is a blue emitting fluorophore with an emission maximum around 480 nm. This dye forms a FRET pair with fluorescein, and can harvest blue light energy for the subsequent transfer to other fluorophores.

The azide derivative can be conjugated with alkynes in a copper-catalyzed and copper-free Click chemistry reactions. The molecule contains a long aminohexanoyl linker that provides separation between the dye, and the azide function.

香豆素 343 是一种蓝色荧光团，最大发射波长约为 480 nm。 这种染料与荧光素形成 FRET 对，并可以收集蓝光能量用于随后转移到其他荧光团。

叠氮化物衍生物可以在铜催化和无铜点击化学反应中与炔烃结合。 该分子含有一个长的氨基己酰基接头，可在染料和叠氮化物功能之间提供分离。

Absorption and emission spectra of Coumarin 343

Coumarin 343 X azide

Coumarin 343 X azide,Coumarin 343 X 叠氮化物相关产品

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cy3 染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 480.3
Molecular weight: 480.56
Molecular formula: C25H32N6O4
IUPAC name: 5-{[6-(3-Azidopropylamino)-6-oxohexylamino]carbonyl}-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-4-one
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 437
ε, L⋅mol−1⋅cm−1: 39000
Emission maximum, nm: 477
Fluorescence quantum yield: 0.63
CF260: 0.29
CF280: 0.24

BDP TR azide,BDP TR 叠氮化物

BDP TR azide,BDP TR 叠氮化物,这是一种叠氮化物，用于铜催化和无铜点击化学标记，使用 BDP TR，一种明亮的红色发射荧光团。 BDP TR 是 ROX 的替代品。 该荧光团基于硼二吡咯亚甲基支架，并含有芳基取代基以匹配其对 ROX 通道的吸收和发射。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP TR azide

BDP TR azide

标签：Azides, BDP TR,Dye azides
货号 规格 价格 货期
13430 1 mg 110.00$ in stock
23430 5 mg 210.00$ in stock
33430 10 mg 310.00$ in stock
43430 25 mg 410.00$ in stock
53430 50 mg 695.00$ in stock
63430 100 mg 1190.00$ in stock

This is an azide for copper catalyzed and copper free Click chemistry labeling with BDP TR, a bright red emitting fluorophore. BDP TR is an alternative to ROX. This fluorophore is based on borondipyrromethene scaffold, and contains aryl substituents to match its absorption and emission to ROX channel.

ROX dye is prone to oxidation, BDP TR is much more resilient to oxidants. Its brightness and photostability is also very high.

这是一种叠氮化物，用于铜催化和无铜点击化学标记，使用 BDP TR，一种明亮的红色发射荧光团。 BDP TR 是 ROX 的替代品。 该荧光团基于硼二吡咯亚甲基支架，并含有芳基取代基以匹配其对 ROX 通道的吸收和发射。

ROX 染料容易氧化，BDP TR 对氧化剂的抵抗力更强。 它的亮度和光稳定性也非常高。

Absorption and emission spectra of BODIPY TR

BDP TR azide

BDP TR azide,BDP TR 叠氮化物相关产品

JOE phosphoramidite, 6-isomer

JOE dye phosphoramidite for synthesis of labeled oligonucleotides. JOE absorption and emission maxima are between maxima of FAM and TAMRA/ROX dyes.

JOE 染料亚磷酰胺用于合成标记的寡核苷酸。 JOE 吸收和发射最大值介于 FAM 和 TAMRA/ROX 染料的最大值之间。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

ROX azide, 5- isomer

ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.

ROX（又名罗丹明 X 或罗丹明 101）叠氮化物，用于通过 Click Chemistry 进行生物分子标记。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 506.2
Molecular weight: 506.34
CAS number: 2183473-27-8
Molecular formula: C24H21N6BF2O2S
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19

BDP TMR azide,BDP TMR 叠氮化物

BDP TMR azide,BDP TMR 叠氮化物,BDP TMR 是一种硼二吡咯亚甲基荧光团（类似于 BODIPY® TMR），其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP TMR azide

BDP TMR azide

标签：Azides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12430 1 mg 110.00$ in stock
22430 5 mg 210.00$ in stock
32430 10 mg 310.00$ in stock
42430 25 mg 410.00$ in stock
52430 50 mg 695.00$ in stock
62430 100 mg 1190.00$ in stock

BDP TMR is a borondipyrromethene fluorophore (analog of BODIPY® TMR) with excitation and emission wavelengths matching TAMRA dye channels. The dye has a long fluorescence lifetime.

This derivative is an azide for Click chemistry labeling.

BDP TMR 是一种硼二吡咯亚甲基荧光团（类似于 BODIPY® TMR），其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

该衍生物是用于点击化学标记的叠氮化物。

Absorption and emission spectra of BODIPY TMR

BDP TMR azide

BDP TMR azide,BDP TMR 叠氮化物相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

BDP TMR azide Add this product to your cart and
get free express delivery

Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

香豆素 343 是一种蓝色荧光团，可作为荧光素 (FAM) 的 FRET 供体。 这种叠氮化物衍生物可以通过点击化学与炔烃结合。 荧光团和叠氮化物基团之间的延伸连接臂增强了溶解度，并提供了染料和生物分子之间的空间分离。

BDP TMR azide Add this product to your cart and
get free express delivery

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

BDP TMR azide Add this product to your cart and
get free express delivery

General properties

Appearance: orange to brown solid 橙色至棕色固体
Mass spec M+ increment: 480.2
Molecular weight: 480.32
CAS number: 2183473-25-6; 2373346-19-9
Molecular formula: C24H27BF2N6O2
Solubility: good in most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献：

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
BODIPY® is a trademark of Life Technologies.

BDP R6G azide,BDP R6G 叠氮化物

BDP R6G azide,BDP R6G 叠氮化物,硼二吡咯亚甲基 (BDP) 染料是高性能荧光团，具有出色的光稳定性和亮度。 有许多 BDP 染料可供选择，它们经过调整以匹配经典呫吨和花青染料的激发和发射通道。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP R6G azide

BDP R6G azide

标签：Azides, BDP R6G
货号 规格 价格 货期
1476-1mg 1 mg 110.00$ in stock
1476-5mg 5 mg 210.00$ in stock
1476-10mg 10 mg 310.00$ in stock
1476-25mg 25 mg 410.00$ in stock
1476-50mg 50 mg 695.00$ in stock

Borondipyrromethene (BDP) dyes are high performance flurophores that exhibit excellent photostability and brightness. A number of BDP dyes is available that are tuned to match excitation and emission channels of classical xanthene and cyanine dyes.

BDP R6G is matched to R6G dye excitation and emission wavelengths. The fluorophore is an excellent alternative to R6G for various applications, including microscopy, fluorescence polarization assays, and two photon experiments.

Azide functional group allows to conjugate the fluorophore easily with various biomolecules, small molecules, and polymers using CuAAC or spAAC Click chemistry reactions.

硼二吡咯亚甲基 (BDP) 染料是高性能荧光团，具有出色的光稳定性和亮度。 有许多 BDP 染料可供选择，它们经过调整以匹配经典呫吨和花青染料的激发和发射通道。

BDP R6G 与 R6G 染料激发和发射波长相匹配。 对于各种应用，包括显微镜、荧光偏振测定和两个光子实验，荧光团是 R6G 的绝佳替代品。

叠氮化物官能团允许使用 CuAAC 或 spAAC Click 化学反应轻松地将荧光团与各种生物分子、小分子和聚合物结合。

Absorption and emission spectra of BODIPY R6G

BDP R6G azide

BDP R6G azide,BDP R6G 叠氮化物相关产品

HEX phosphoramidite, 6-isomer

HEX phosphoramidite for synthesis of 5’-labeled oligonucleotides.

用于合成 5′ 标记寡核苷酸的 HEX 亚磷酰胺。

Pyrene azide 1

Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.

通过 Click Chemistry 用芘多环芳烃进行荧光标记的试剂。

BDP 650/665 X NHS ester

Amine reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel, possessing a high molar extinction coefficient, and a good emission quantum yield.

BDP 650/665 的胺反应物，一种用于 Cy5 通道的硼二吡咯亚甲基染料，具有高摩尔消光系数和良好的发射量子产率。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 422.24
CAS number: 2183473-23-4
Molecular formula: C21H21N6BF2O
IUPAC name: 3-(3-(4,4-Difluoro-5-phenyl-3a,4a-diaza-4-bora-s-indacen-3-yl)propionylamino)propylazide
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL azide

BDP FL azide,BDP FL azide 是 BODIPY® FL azide 的类似物，BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。这种发绿光的荧光团与所有类型的 FAM（荧光素）荧光测量仪器兼容。荧光团是硼二吡咯亚甲基类荧光染料的代表，它在水性环境中具有高量子产率，并且对光漂白具有高稳定性。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP FL azide

BDP FL azide

标签：BDP FL,Azides,Fluorescence polarization,Microscopy
货号 规格 价格 货期
11430 1 mg 110.00$ in stock
21430 5 mg 210.00$ in stock
31430 10 mg 310.00$ in stock
41430 25 mg 410.00$ in stock
51430 50 mg 695.00$ in stock
61430 100 mg 1190.00$ in stock

BDP FL azide is an analog of BODIPY® FL azide, a Click-chemistry capable bright and photostable dye for FAM channel.

This green-emitting fluorophore is compatible with all types of fluorescence measuring instruments for FAM (fluorescein).

The fluorophore is a representative of borondipyrromethene class of fluorescent dyes, which possess high quantum yields in aqueous environments, and high stability towards photobleaching.

BDP FL azide 是 BODIPY® FL azide 的类似物，BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。

这种发绿光的荧光团与所有类型的 FAM（荧光素）荧光测量仪器兼容。

荧光团是硼二吡咯亚甲基类荧光染料的代表，它在水性环境中具有高量子产率，并且对光漂白具有高稳定性。

BDP FL azide BDP FL azide BDP FL azide BDP FL azide

Absorption and emission spectra of BDP FL

BDP FL azide

BDP FL azide相关产品

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

General properties一般属性

Appearance: orange solid
Molecular weight: 374.20
CAS number: 1379771-95-5, 2243566-18-7
Molecular formula: C17H21BF2N6O
Solubility: soluble in organic solvents (alcohols, DMF, DMSO)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties光谱特性

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
  2. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  3. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  4. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319
BODIPY® is a trademark of Life Technologies.

BDP 650/665 azide

BDP 650/665 azide,BDP 650/665 是一种明亮的红色发光硼二吡咯亚甲基染料，与许多仪器上的 Cy5 通道兼容。 这是 BDP 650/665 的叠氮化物衍生物。 它可以通过铜催化反应与末端炔烃结合，或通过无铜点击化学与环炔烃结合。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 650/665 azide

BDP 650/665 azide

标签：Azides,Near infrared (NIR) imaging,BDP 650/665
货号 规格 价格 货期
18430 1 mg 110.00$ in stock
28430 5 mg 210.00$ in stock
38430 10 mg 310.00$ in stock
48430 25 mg 410.00$ in stock
58430 50 mg 695.00$ in stock
68430 100 mg please inquire in stock

BDP 650/665 is a bright red emitting borondipyrromethene dye, compatible with Cy5 channel found on many instruments. This is azide derivative of BDP 650/665. It can be conjugated with terminal alkynes via copper catalyzed reaction, or with cycloalkynes via copper-free Click chemistry.

BDP 650/665 azide can be conjugated with various terminal alkynes using copper-catalyzed Click chemistry, or with cycloalkynes using a copper-free reaction.

BDP 650/665 是一种明亮的红色发光硼二吡咯亚甲基染料，与许多仪器上的 Cy5 通道兼容。 这是 BDP 650/665 的叠氮化物衍生物。 它可以通过铜催化反应与末端炔烃结合，或通过无铜点击化学与环炔烃结合。

BDP 650/665 叠氮化物可以使用铜催化的点击化学与各种末端炔烃偶联，或使用无铜反应与环炔烃偶联。

BDP 650/665 azide

Absorption and emission spectra of BDP 650/665

BDP 650/665 azide

BDP 650/665 azide相关产品

Pyrene azide 1

Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.

通过 Click Chemistry 用芘多环芳烃进行荧光标记的试剂。

Alkyne CPG modifier 500

Solid support for the synthesis of 3′-modified oligonucleotides with alkyne group for Click Chemistry.

Cy3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

为 Click Chemistry 合成具有Cy3′-修饰寡核苷酸提供坚实支持。

General properties

Appearance: dark colored solid
Molecular weight: 515.32
Molecular formula: C26H24N7BF2O2
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

BDP 630/650 azide

BDP 630/650 azide,BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物，适用于光谱的远红色区域，用于使用 Click 化学进行标记。该染料具有较长的激发态寿命，因此可用于荧光偏振实验。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 630/650 azide

BDP 630/650 azide

标签：Azides,Fluorescence polarization,Microscopy,BDP 630/650
货号 规格 价格 货期
15430 1 mg 110.00$ in stock
25430 5 mg 210.00$ in stock
35430 10 mg 310.00$ in stock
45430 25 mg 410.00$ in stock
55430 50 mg 695.00$ in stock

BDP 630/650 azide is a bright and photostable dye azide for the far red region of the spectrum, for labeling using Click chemistry.

This dye possesses a relatively long lifetime of the excited state, and can therefore be used for fluorescence polarization experiments.

BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物，适用于光谱的远红色区域，用于使用 Click 化学进行标记。

该染料具有较长的激发态寿命，因此可用于荧光偏振实验。

BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide

Absorption and emission spectra of BDP 630/650

BDP 630/650 azide

BDP 630/650 azide相关产品

Cy5.5 maleimide

Cy5.5 maleimide is a thiol reactive dye for protein labeling.
Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.
用于点击化学的 TAMRA 荧光染料叠氮化物。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cyanine5 荧光团的远红通道。

General properties

Appearance: dark colored powder
Mass spec M+ increment: 532.2
Molecular weight: 532.37
CAS number: 2183473-22-3
Molecular formula: C26H23N6BF2O2S
IUPAC name: Boron, [N-​(3-​azidopropyl)​-​2-​[4-​[2-​[5-​[[5-​(2-​thienyl)​-​2H-​pyrrol-​2-​ylidene-​κN]​methyl]​-​1H-​pyrrol-​2-​yl-​κN]​ethenyl]​phenoxy]​acetamidato]​difluoro-​, (T-​4)​- Coordination Compound
Solubility: good in DMSO, DMF, acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 azide

BDP 581/591 azide,BDP 581/591 是一种明亮的多功能荧光团，具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 581/591 azide

BDP 581/591 azide

标签：Azides,Fluorescence polarization,Microscopy,BDP 581/591
货号 规格 价格 货期
16430 1 mg 110.00$ in stock
26430 5 mg 210.00$ in stock
36430 10 mg 310.00$ in stock
46430 25 mg 410.00$ in stock
56430 50 mg 695.00$ in stock

BDP 581/591 is a bright and versatile fluorophore that is relatively hydrophobic. It has a high brightness, significant two photon cross-section, and relatively long fluorescence lifetime.

The dye reacts with reactive oxygen species (ROS) with the change of its fluorescence. It can be therefore used for intracellular monitoring of ROS.

This is an azide derivative that can be used for the conjugation with both small molecules and biomolecules to construct tracers for fluorescence polarization assays and microscopy probes.

BDP 581/591 是一种明亮的多功能荧光团，具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

染料与活性氧 (ROS) 发生反应并改变其荧光。 因此，它可用于细胞内 ROS 的监测。

这是一种叠氮化物衍生物，可用于与小分子和生物分子结合，以构建荧光偏振测定和显微探针的示踪剂。

BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide

Absorption and emission spectra of BDP 581/591

BDP 581/591 azide

BDP 581/591 azide相关产品

BDP 630/650 alkyne

Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.

用于铜催化点击化学的炔烃染料，含有用于红色通道的硼二吡咯亚甲基荧光团 BDP 630/650。

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物，用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验，并可用作 ROS 探针。

Cy7 NHS ester

Amine reactive NHS ester of near infrared dye Cy7.

近红外染料 Cy7 的胺活性 NHS 酯。

General properties

Appearance: dark solid
Molecular weight: 474.31
Molecular formula: C25H25N6BF2O
Solubility: good in DCM, alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 azide, BDP 558/568 叠氮化物

BDP 558/568 azide, BDP 558/568 叠氮化物,BDP 558/568 azide 是一种用于点击化学的具有叠氮化物官能团的硼二吡咯亚甲基染料。 其光谱接近Cyanine3通道。 荧光团已用作 BDP 558/568 C12 用于脂质追踪，但叠氮官能团可轻松与多种其他感兴趣的分子结合。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 558/568 azide

BDP 558/568 azide

标签：Azides, Click chemistry, BDP 558/568
货号 规格 价格 货期
17430 1 mg 110.00$ in stock
27430 5 mg 210.00$ in stock
37430 10 mg 310.00$ in stock
47430 25 mg 410.00$ in stock
57430 50 mg 695.00$ in stock
67430 100 mg please inquire in stock

BDP 558/568 azide is a borondipyrromethene dye with azide functional group for Click chemistry. Its spectra are close to Cyanine3 channel. The fluorophore has been used for lipid tracking as BDP 558/568 C12, but azide functional groups allow easy conjugation with a wide variety of other molecules of interest.

BDP 558/568 azide 是一种用于点击化学的具有叠氮化物官能团的硼二吡咯亚甲基染料。 其光谱接近Cyanine3通道。 荧光团已用作 BDP 558/568 C12 用于脂质追踪，但叠氮官能团可轻松与多种其他感兴趣的分子结合。

Absorption and emission spectra of BDP 558/568

BDP 558/568 azide

BDP 558/568 azide, BDP 558/568 叠氮化物相关产品

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cyanine3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

氨基反应性 BDP FL，一种非常明亮且光稳定的荧光素通道染料。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 428.1
Molecular weight: 428.27
Molecular formula: C19H19N6BF2OS
Solubility: soluble in many organic solvents (DCM, acetone, alcohols, DMF, DMSO), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07

3-азидопропиламин,3-叠氮基丙胺

3-азидопропиламин,3-叠氮基丙胺

  • Products
  • Click chemistry
  • Non-fluorescent azides
  • 3-азидопропиламин
Some content on this page is not available in English and displayed by default in the language currently available.

3-азидопропиламин,3-叠氮基丙胺

Azides, Amines, Click chemistry
货号 规格 价格 货期
58-100mg 100 mg 110.00$ 21 days
58-1g 1 g 400.00$ 21 days
58-5g 5 g please inquire 21 days

Азидопропиламин-реагент с терминальными амино- и азидогруппами, широко используемый в реакциях Click Chemistry и хорошо растворимый в воде.

Азидопропиламин применяется для введения азидного фрагмента в молекулы, содержащие карбоксильные группы с помощью активации последних карбодиимидом и взаимодействия с аминогруппой 3-азидопропиламина. Подобные соединения с терминальной азидной группой могут вступать в реакции Cu(I)-катализируемого азидо-алкинового [3+2]-циклоприсоединения.

Также азидопропиламин может использоваться в пептидном синтезе для модификации пептидов с активированными HBTU и HOBt карбоксильными группами.

叠氮基丙胺是一种具有末端氨基和叠氮基的试剂，广泛用于点击化学反应，极易溶于水。

叠氮基丙胺用于通过用碳二亚胺活化后者并与 3-叠氮基丙胺的氨基相互作用，将叠氮片段引入含有羧基的分子中。具有末端叠氮基的类似化合物可以进入 Cu(I) 催化的叠氮基-炔烃 [3+2]-环加成反应。

叠氮基丙胺也可用于肽合成，以修饰具有活化 HBTU 和 HOBt 羧基的肽。

Общие свойства

Вид продукта: бесцветная жидкость 无色液体
Молекулярная масса: 100.12
CAS-номер: 88192-19-2
Брутто-формула: C3H8N4
Название IUPAC: 3-Azido-1-propanamine
Растворимость: растворим в воде, ДМСО, ДМФ, дихлорметане, ТГФ, хлороформе

溶于水、DMSO、DMF、二氯甲烷、THF、氯仿
Контроль качества: ЯМР 1H, ГХ-МС (95%)
Условия хранения: Хранение: 24 месяца (с момента доставки) при -20°C в темноте. Транспортировка: до трех недель при комнатной температуре.

储存：-20°C 避光保存 24 个月（从交货开始）。 运输：室温下最多三周。
MSDS: Download
Product specifications

Azide-PEG4-Azide

Azide-PEG4-Azide,PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰，或者通过铜催化与末端炔烃的反应，或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG4-Azide

Azide-PEG4-Azide

标签：Azides,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1865-1g 1 g 90.00$ in stock
1865-5g 5 g 250.00$ in stock
1865-25g 25 g 950.00$ in stock
PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by Click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.

This diazide is useful for the synthesis of dimeric molecules by Click chemistry.

PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰，或者通过铜催化与末端炔烃的反应，或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

这种二叠氮化物可用于通过点击化学合成二聚体分子。

Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide

Azide-PEG4-Azide相关产品

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯，用于标记蛋白质、肽和其他分子。

General properties

Appearance: colorless liquid
Molecular weight: 244.25
CAS number: 101187-39-7
Molecular formula: C8H16N6O3
Solubility: miscible with water, polar organic solvents
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Azide-PEG4-Amine

Azide-PEG4-Amine,低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å，因此 PEG4 的长度约为 14 Å (1.4 nm)。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG4-Amine

Azide-PEG4-Amine

标签：Azides,Amines,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1868-1g 1 g 90.00$ in stock
1868-5g 5 g 250.00$ in stock
1868-25g 25 g 950.00$ in stock
Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so that the length of PEG4 is around 14 Å (1.4 nm).

Azide-PEG4-Amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds, and an azide group that is suitable for Click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å，因此 PEG4 的长度约为 14 Å (1.4 nm)。

叠氮化物-PEG4-Amine 是一种双官能化合物，具有可通过活化酯或类似羰基化合物酰化修饰的胺基，以及适用于 Click 化学反应的叠氮基。 PEG4 具有高度亲水性和生物相容性。

Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine

Azide-PEG4-Amine相关产品

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

一种双功能连接分子，包含用于点击化学的末端炔烃部分和胺基。 包含一个长的亲水性 PEG4 臂。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

General properties

Appearance: colorless to yellowish liquid
Molecular weight: 218.25
CAS number: 134179-38-7
Molecular formula: C8H18N4O3
Solubility: miscible with water, polar organic solvents
Quality control: NMR 1H,GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid,Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的，适合合成水溶性结合物。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid

标签：Azides,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
2558-1g 1 g 265.00$ in stock
2558-5g 5 g 950.00$ in stock
Azide-PEG3-Carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.

This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (Click Chemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的，适合合成水溶性结合物。

叠氮基可以与含有炔烃部分的生物分子发生[3+2]-偶极环加成反应（点击化学反应），羧基可以被活化并与各种胺反应。

合成的生物偶联物的库可以非常广泛； 例如，可以使用这种方法生成不同的抗体-药物偶联物 (ADC)。 此外，PEG 接头与分子的缀合可以增加其在水中的稳定性和溶解度，并降低免疫原性。

Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid相关产品

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.

具有末端炔烃功能和羧酸部分的双功能接头，CAS# 1415800-32-6。

Azide-PEG3-OH

Azide-PEG3-OH is a bifunctional molecule with azide group, primary alcohol, and a hydrophilic linker in between.

叠氮化物-PEG3-OH 是一种双功能分子，具有叠氮基、伯醇和介于两者之间的亲水性接头。

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

General properties

Appearance: colorless liquid
Molecular weight: 247.25
CAS number: 1056024-94-2
Molecular formula: C9H17N3O5
IUPAC name: 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。
MSDS: Download
Product specifications

Azide-PEG3-Azide

Azide-PEG3-Azide,PEG3（三甘醇）二叠氮化物（1,8-diazido-3,6-dioxaoctane）是一种对称的双功能交联剂，带有两个叠氮基。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Azide

Azide-PEG3-Azide

标签：Azides,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
207-1g 1 g 95.00$ in stock
207-5g 5 g 390.00$ in stock
207-25g 25 g please inquire in stock
PEG3 (triethylene glycol) diazide (1,8-diazido-3,6-dioxaoctane) is a symmetrical bifunctional crosslinker bearing two azide groups.
PEG3（三甘醇）二叠氮化物（1,8-diazido-3,6-dioxaoctane）是一种对称的双功能交联剂，带有两个叠氮基。

Azide-PEG3-Azide Azide-PEG3-Azide Azide-PEG3-Azide > Azide-PEG3-Azide

Azide-PEG3-Azide相关产品

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 200.2
CAS number: 59559-06-7
Molecular formula: C6H12N6O2
IUPAC name: 1,8-diazido-3,6-dioxaoctane, 1,2-bis(2-azidoethoxy)ethane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  2. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f

Azide-PEG3-Amine

Azide-PEG3-Amine,叠氮化物-PEG3-胺是一种双功能试剂，具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物（通过胺基的酰化）与炔烃（通过点击化学反应）的缀合。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Amine

Azide-PEG3-Amine

标签：Azides,Amines,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
218-1g 1 g 95.00$ in stock
218-5g 5 g 280.00$ in stock
218-25g 25 g please inquire in stock
Azide-PEG3-amine is a bifunctional reagent with an azide group, and an amine group flanking triethylene glycol. This linker is useful for the conjugation of carboxylic derivatives (by acylation of the amine group) with alkynes (via a Click chemistry reaction).
叠氮化物-PEG3-胺是一种双功能试剂，具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物（通过胺基的酰化）与炔烃（通过点击化学反应）的缀合。

Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine

Azide-PEG3-Amine相关产品

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

General properties

Appearance: colorless/yellowish oil
Molecular weight: 174.2
CAS number: 166388-57-4
Molecular formula: C6H14N4O2
IUPAC name: 1-Amino-8-azido-3,6-dioxaoctane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GCMS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

Iodo-PEG3-Azide

Iodo-PEG3-Azide,Iodo-PEG3-Azide 含有一个高反应性的碘化物官能团，可以烷基化各种 C-、O-、N-、S-中心和其他亲核试剂。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Iodo-PEG3-Azide

Iodo-PEG3-Azide

标签：Azides, PEG3 (triethylene glycol), Halogenides, Iodides
货号 规格 价格 货期
2163-1g 1 g 290.00$ in stock
2163-5g 5 g 590.00$ in stock
2163-25g 25 g 2490.00$ in stock

Iodo-PEG3-Azide contains a highly reactive iodide functional group which can alkylate a variety of C-, O-, N-, S-centered and other nucleophiles.

Organic iodides are roughly an order of magnitude more active than bromides, and four orders of magnitude more active than chlorides in SN2 reactions. This means that the same alkylation will take 10x less time with iodide than with bromide. Therefore, this molecule helps to effect very fast alkylation.

PEG3 is a moderately long hydrophilic linker. The azide group participates in Click chemistry reactions. It is also easily reduced to an amine group.

Iodo-PEG3-Azide 含有一个高反应性的碘化物官能团，可以烷基化各种 C-、O-、N-、S-中心和其他亲核试剂。

在 SN2 反应中，有机碘化物的活性大约比溴化物高一个数量级，比氯化物高四个数量级。 这意味着使用碘化物进行相同的烷基化反应所需的时间比使用溴化物的时间少 10 倍。 因此，这种分子有助于实现非常快速的烷基化。

PEG3 是中等长度的亲水接头。 叠氮基参与点击化学反应。 它也很容易被还原为胺基。

Iodo-PEG3-Azide相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

PEG3-tetrazine

PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for ied-DA conjugation with strained olefins.

PEG3 四嗪是一种具有四嗪基团的单反应性三甘醇，用于与应变烯烃的 ied-DA 缀合。

Iodo-PEG3-Acid

A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.

一种含有羧酸官能团和碘化物、活性卤素基团的双官能化合物。

General properties

Appearance: colorless to yellow oil 无色至黄色油状物
Molecular weight: 285.08
CAS number: 1309457-01-9
Molecular formula: C6H12N3IO2
IUPAC name: 1-(2-azidoethoxy)-2-(2-iodoethoxy)ethane
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 干燥。
MSDS: Download
Product specifications

Chloro-PEG3-Azide

Chloro-PEG3-Azide,Chloro-PEG3-Azide 是一种异双功能接头，带有用于烷基化各种亲核基团的反应性氯化物。 由于氧的非嵌合辅助，该原子比正常的烷基氯化物更具反应性。 另一个反应基团是叠氮化物。 它可以通过点击化学结合，或还原为胺基，然后与反应性羰基化合物进行酰化。

  • Products
  • Click chemistry
  • Non-fluorescent azides
  • Chloro-PEG3-Azide

Chloro-PEG3-Azide

标签：Azides, PEG3 (triethylene glycol), Halogenides
货号 规格 价格 货期
2106-1g 1 g 490.00$ 21 days

Chloro-PEG3-Azide is a heterobifunctional linker bearing a reactive chloride for the alkylation of various nucleophilic groups. Due to anchimeric assistance from oxygen, this atom is more reactive than in normal alkyl chlorides. The other reactive group is azide. It can be conjugated via Click chemistry, or reduced to amine group to be later acylated with reactive carbonyl compounds.

PEG3 is a versatile hydrophilic linker for bioconjugation.

Chloro-PEG3-Azide 是一种异双功能接头，带有用于烷基化各种亲核基团的反应性氯化物。 由于氧的非嵌合辅助，该原子比正常的烷基氯化物更具反应性。 另一个反应基团是叠氮化物。 它可以通过点击化学结合，或还原为胺基，然后与反应性羰基化合物进行酰化。

PEG3 是用于生物偶联的多功能亲水接头。

Chloro-PEG3-Azide相关产品

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

具有叠氮化物和胺基的双功能接头，位于 PEG3（三甘醇）的两侧

Iodo-PEG3-Iodide

Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.

具有卤素反应基团的基于同双功能 PEG3 的接头可用于亲核试剂的交联。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头，具有羟基和炔烃片段。

General properties

Appearance: colorless oil 无色油
Molecular weight: 193.63
Molecular formula: C6H12N3ClO2
IUPAC name: 1-(2-Azidoethoxy)-2-(2-chloroethoxy)ethane
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Biotin-PEG3-Azide

Biotin-PEG3-Azide,生物素叠氮化物是与叠氮基共价结合的生物素（维生素 H）的衍生物。 该试剂允许用生物素标记各种炔基化分子（如 DNA、寡核苷酸和蛋白质）。 与亲和素或链霉亲和素结合的生物素可用于下游亲和应用，以分离生物素化分子或它们与链霉亲和素缀合物的结合。

  • Products
  • Click chemistry
  • Non-fluorescent azides
  • Biotin-PEG3-Azide

Biotin-PEG3-Azide

标签：Azides, PEG3 (triethylene glycol)
货号 规格 价格 货期
C3730 10 mg 40.00$ in stock
D3730 25 mg 90.00$ in stock
E3730 50 mg 140.00$ in stock
F3730 100 mg 180.00$ in stock

Biotin azide is a derivative of biotin (vitamin H) covalently bound with azide group. This reagent allows labeling of various alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin. Biotin binding to avidin or streptavidin can be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates.

This structure of biotin azide features long hydrophilic linker which separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker (PEG) also enhances aqueous solubility to facilitate conjugation.

The azide can be conjugated with various molecules using our recommended protocol.

生物素叠氮化物是与叠氮基共价结合的生物素（维生素 H）的衍生物。 该试剂允许用生物素标记各种炔基化分子（如 DNA、寡核苷酸和蛋白质）。 与亲和素或链霉亲和素结合的生物素可用于下游亲和应用，以分离生物素化分子或它们与链霉亲和素缀合物的结合。

生物素叠氮化物的这种结构具有长的亲水性接头，可将生物素残基与靶分子分开，从而与链霉亲和素有效结合。 它的接头 (PEG) 还增强了水溶性以促进结合。

使用我们推荐的方案，叠氮化物可以与各种分子结合。

Biotin-PEG3-Azide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP（苯乙炔基芘），用于 Click-Chemistry 标记的多环芳烃荧光染料。

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

General properties

Appearance: colorless solid 无色固体
Molecular weight: 400.50
CAS number: 945633-30-7
Molecular formula: C16H28N6O4S
Solubility: soluble in DMF, DMSO, moderately soluble in water
Quality control: NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks.

储存：-20°C 收货后 24 个月。 运输：在室温下长达 3 周。
MSDS: Download
Product specifications

相关文献：

  1. Dettling, S.E.; Ahmadi, M.; Lin, Z.; He, L.; Matthews, M.L. Discovery of Electrophiles and Profiling of Enzyme Cofactors. Current Protocols in Chemical Biology, 2020, 12(4), e86. doi: 10.1002/cpch.86
  2. Wang, Y.; Dattmore, D.A.; Wang, W:; Pohnert, G.; Wolfram, S.; Zhang, J.; Yang, R.; Decker, E.A.; Lee, K.S.S.; Zhang, G. trans, trans-2,4-decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14–3-3ζ-dependent mechanisms. Journal of Nutritional Biochemistry, 2020, 76, 108286. doi: 10.1016/j.jnutbio.2019.108286
  3. Shen, Y.; Yang, S.; Hu, X.; Zhang, M.; Ma, X.; Wang, Z.; Hou, Y.; Bai, G. Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells. Journal of Functional Foods, 2019, 55, 296–304. doi: 10.1016/j.jff.2019.02.035
  4. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067

Azide-PEG3-OH

Azide-PEG3-OH,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-OH

Azide-PEG3-OH

标签：Azides, PEG3 (triethylene glycol),Bifunctional crosslinkers
货号 规格 价格 货期
1742-1g 1 g 90.00$ in stock

Heterobifunctional crosslinker with a primary alcohol functional group, azide group, and a PEG3 hydrophilic linker.

具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

Azide-PEG3-OH相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cyanine5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头，具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

General properties

Appearance: colorless liquid 无色液体
Molecular weight: 175.19
CAS number: 86520-52-7
Molecular formula: C6H13N3O3
IUPAC name: 2-[2-(2-azidoethoxy)ethoxy]-ethanol
Solubility: miscible with water, most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

AmdU (5-azidomethyl-2′-deoxyuridine)

AmdU (5-azidomethyl-2′-deoxyuridine),叠氮甲基-dU (AmdU) 是一种含有叠氮基的核苷。 核苷的结构类似于胸苷，它通过细胞聚合酶掺入新生DNA中，类似于EdU。

  • Products
  • Click chemistry
  • Non-fluorescent azides
  • AmdU (5-azidomethyl-2′-deoxyuridine)

AmdU (5-azidomethyl-2′-deoxyuridine)

标签：Azides, Copper free Click chemistry
货号 规格 价格 货期
B1540 5 mg 120.00$ in stock
D1540 25 mg 255.00$ in stock
F1540 100 mg 890.00$ in stock</td

Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU.

Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.

叠氮甲基-dU (AmdU) 是一种含有叠氮基的核苷。 核苷的结构类似于胸苷，它通过细胞聚合酶掺入新生DNA中，类似于EdU。

与需要在铜催化剂存在下用叠氮化物进一步改性的 EdU 不同，AmdU 也可以在没有铜催化剂的情况下使用 spAAC Click Chemistry 与应变的环炔烃（例如环辛炔）发生反应。 这使得在良性、无铜条件下检测新生 DNA 成为可能。

AmdU (5-azidomethyl-2′-deoxyuridine)相关产品

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cy3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

General properties

Appearance: white / off white solid 白色/米白色固体
Molecular weight: 283.24
Molecular formula: C10H13N5O5
IUPAC name: 5-Azidomethyl-2′-deoxyuridine
Solubility: good in water, alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

TAMRA azide, 6-isomer,叠氮化物,Dye azides

TAMRA azide, 6-isomer,叠氮化物,Dye azides,四甲基罗丹明 (TAMRA) 是一种具有橙色发射光的呫吨染料。 该染料是 FAM 的 FRET 受体，有时用作它的猝灭剂。

  • Products
  • Reactive dyes
  • Dye azides
  • TAMRA azide, 6-isomer

TAMRA azide, 6-isomer

标签：Azides, TAMRA (TMR, tetramethylrhodamine),叠氮化物,Dye azides
货号 规格 价格 货期
A8130 1 mg 110.00$ in stock
B8130 5 mg 180.00$ in stock
C8130 10 mg 310.00$ in stock
D8130 25 mg 410.00$ in stock
E8130 50 mg 695.00$ in stock
F8130 100 mg 1190.00$ in stock

Tetramethylrhodamine (TAMRA) is a xanthene dye with orange emission. The dye is a FRET acceptor for FAM, and sometimes used as a quencher for it.

Like other xanthenes, TAMRA exists as two isomers (5- and 6-), which have very similar spectral properties. This is an azide derivative of 6-isomer of TAMRA. The azide can be conjugated with terminal alkynes using copper-catalyzed Click chemistry, or with cycloalkynes with copper-free strain promoted alkyne azide cycloaddition (spAAc) reaction.

四甲基罗丹明 (TAMRA) 是一种具有橙色发射光的呫吨染料。 该染料是 FAM 的 FRET 受体，有时用作它的猝灭剂。

与其他呫吨一样，TAMRA 以两种异构体（5-和 6-）存在，它们具有非常相似的光谱特性。 这是TAMRA 6-异构体的叠氮化物衍生物。 叠氮化物可以使用铜催化的点击化学与末端炔烃缀合，或与环炔烃缀合，无铜应变促进炔烃叠氮化物环加成 (spAAc) 反应。

TAMRA azide, 6-isomer相关产品

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: violet solid / solution 紫色固体/溶液
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 1192590-89-8
Molecular formula: C28H28N6O4
Solubility: Good in DMF, DMSO, alcohols, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  2. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  3. Chen, X.; Xu, J.; Wong, N.-K.; Zhong, S.; Yang, M.; Liu, Z.; Lu, Y.; Li, W.; Zhou, Y. Chemoproteomic profiling of cobalamin-independent methionine synthases in plant with a covalent probe. Journal of Agricultural and Food Chemistry, 2020, 68(30), 8050–8056. doi: 10.1021/acs.jafc.0c03301
  4. Xu, Y.; Deng, Z.; Shi, Y.; Chen, X.; Xu, J.; Zhong, S.; Xiao, Y.; Wong, N.-K.; Zhou, Y. Molecular Imaging and In Situ Quantitative Profiling of Fatty Acid Synthase with a Chemical Probe. Analytical Chemistry, 2020, 92(6), 4419–4426. doi: 10.1021/acs.analchem.9b05327

TAMRA azide, 5-isomer,叠氮化物,Dye azides

TAMRA azide, 5-isomer,叠氮化物,Dye azides,TAMRA（TMR，四甲基罗丹明）叠氮化物、固体化合物和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 纯5-异构体。

  • Products
  • Reactive dyes
  • Dye azides
  • TAMRA azide, 5-isomer

TAMRA azide, 5-isomer

标签：Azides, TAMRA (TMR, tetramethylrhodamine),叠氮化物,Dye azides
货号 规格 价格 货期
A7130 1 mg 110.00$ in stock
B7130 5 mg 180.00$ 5 days
C7130 10 mg 310.00$ in stock
D7130 25 mg 410.00$ in stock
E7130 50 mg 695.00$ in stock
F7130 100 mg 1190.00$ in stock

TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.

TAMRA is often used as FRET acceptor for FAM fluorophore.

TAMRA（TMR，四甲基罗丹明）叠氮化物、固体化合物和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 纯5-异构体。

TAMRA 通常用作 FAM 荧光团的 FRET 受体。

Can replace DyLight 549.

Absorption and emission spectra of 5-TAMRA

TAMRA azide, 5-isomer

TAMRA azide, 5-isomer,叠氮化物,Dye azides相关产品

Sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3 analog.

Sulfo-Cyanine3 的水溶性硫醇反应性衍生物，一种 Cy3 类似物。

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

General properties

Appearance: violet solid / solution 紫色固体/溶液
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 825651-66-9
Molecular formula: C28H28N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  2. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  3. Seneviratne, U.; Huang, Z.; Am Ende, C.W.; Butler, T.W.; Cleary, L.; Dresselhaus, E.; Evrard, E.; Fisher, E.L.; Green, M.E.; Helal, C.J.; Humphrey, J.M.; Lanyon, L.F.; Marconi, M.; Mukherjee, P.; Sciabola, S.; Steppan, C.M.; Sylvain, E.K.; Tuttle, J.B.; Verhoest, P.R.; Wager, T.T.; Xie, L.; Ramaswamy, G.; Johnson, D.S.; Pettersson, M. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE. Cell Chemical Biology, 2021, 28(2), 148–157.e7. doi: 10.1016/j.chembiol.2020.09.002
  4. Zhang, M.; Zhou, L.; Xu, Y.; Yang, M.; Xu, Y.; Komaniecki, G.P.; Kosciuk, T.; Chen, X.; Lu, X.; Zou, X.; Linder, M.E.; Lin, H. A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis. Nature, 2020, 586(7829), 434–439. doi: 10.1038/s41586-020-2799-2

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides,Sulfo-Cyanine7.5 是一种七甲炔花青染料，适用于光谱的近红外区域，具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG（吲哚菁绿），甚至被批准用于人体血管造影。 然而，与 ICG 相比，磺基-Cyanine7.5 具有显着提高的荧光量子产率，这是由于用三亚甲基桥加强的崎岖多甲炔链。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide

标签：Azides, Near infrared (NIR) imaging, sulfo-Cyanine7.5,Cy7.5,叠氮化物,Dye azides
货号 规格 价格 货期
A6330 1 mg 110.00$ in stock
B6330 5 mg 290.00$ in stock
C6330 10 mg 470.00$ in stock
D6330 25 mg 690.00$ in stock
E6330 50 mg 1270.00$ in stock
F6330 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a heptamethyne cyanine dye for the near infrared region of the spectrum, which is very hydrophilic, and water soluble. The fluorophore resembles ICG (indocyanine green) that has a long history of in vivo use, and is even approved for human angiography. However, compared to ICG, sulfo-Cyanine7.5 has a significantly improved fluorescence quantum yield due to the rugged polymethine chain reinforced with trimethylene bridge.

Sulfo-Cyanine7.5 is available as a number of reactive derivatives. This azide can be used for the easy labeling of various biomolecules by copper-catalyzed or copper free Click chemistry.

Sulfo-Cyanine7.5 是一种七甲炔花青染料，适用于光谱的近红外区域，具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG（吲哚菁绿），甚至被批准用于人体血管造影。 然而，与 ICG 相比，磺基-Cyanine7.5 具有显着提高的荧光量子产率，这是由于用三亚甲基桥加强的崎岖多甲炔链。

Sulfo-Cyanine7.5 可作为许多反应性衍生物使用。 这种叠氮化物可用于通过铜催化或无铜点击化学轻松标记各种生物分子。

Absorption and emission spectra of sulfo-Cyanine7.5 fluorophore

Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性，推荐用于水环境中生物分子的标记。

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 1050.3
Molecular weight: 1165.51
Molecular formula: C48H51N6K3O13S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Sulfo-Cyanine7 azide,Cy7 叠氮化物

Sulfo-Cyanine7 azide,Cy7 叠氮化物,一种用于 Click Chemistry 的水溶性 NIR 染料叠氮化物。 Sulfo-Cyanine7 是一种花青染料，是 Cy7® 的类似物，具有改进的光物理特性。这种染料是活体生物近红外成像研究的完美选择。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine7 azide

Sulfo-Cyanine7 azide

标签：sulfo-Cyanine7, Cy7,Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
A5330 1 mg 110.00$ in stock
B5330 5 mg 290.00$ in stock
C5330 10 mg 470.00$ in stock
D5330 25 mg 690.00$ in stock
E5330 50 mg 1270.00$ in stock
F5330 100 mg 1990.00$ in stock

A water-soluble NIR dye azide for Click Chemistry. Sulfo-Cyanine7 is a cyanine dye, an analog of Cy7® with improved photophysical properties.

This dye is a perfect choice for NIR imaging studies in live organisms.

一种用于 Click Chemistry 的水溶性 NIR 染料叠氮化物。 Sulfo-Cyanine7 是一种花青染料，是 Cy7® 的类似物，具有改进的光物理特性。

这种染料是活体生物近红外成像研究的完美选择。

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 azide

Sulfo-Cyanine7 azide,Cy7 叠氮化物相关产品

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

Sulfo-Cy7 羧酸是一种非反应性荧光染料，可用作 NIR（近红外）标记。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 829.08
Molecular formula: C40H49N6KO7S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物,Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团，在光谱的远红色区域具有发射，是 Cy5.5® 的类似物。 与其他花青染料一样，sulfo-Cyanine5.5 具有出色的摩尔消光系数，从而产生明亮的荧光。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide

标签：Azides, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A7330 1 mg 110.00$ 5 days
B7330 5 mg 290.00$ in stock
C7330 10 mg 470.00$ in stock
D7330 25 mg 690.00$ in stock
E7330 50 mg 1270.00$ in stock
F7330 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore which possesses emission in far red area of the spectrum, an analog of Cy5.5®. As other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient which gives rise to its bright fluorescence.

The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore – this minimizes non-specific binding.

The azide group of sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst, or with cycloalkynes in copper free strain promoted reaction.

Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团，在光谱的远红色区域具有发射，是 Cy5.5® 的类似物。 与其他花青染料一样，sulfo-Cyanine5.5 具有出色的摩尔消光系数，从而产生明亮的荧光。

该分子含有四个磺基，可为荧光团提供亲水性和负电荷 – 这最大限度地减少了非特异性结合。

磺基-Cyanine5.5 叠氮化物的叠氮基团可以在铜（I）催化剂存在下与末端炔烃共轭，或在无铜应变促进反应中与环炔烃共轭。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

BDP 581/591 azide

BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.

BDP 581/591 是一种相对疏水的硼二吡咯亚甲基荧光团，可用作 ROS 物种的探针或荧光偏振示踪剂。 这是一种用于点击化学的叠氮化物衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 984.2
Molecular weight: 1099.41
CAS number: 2382994-65-0
Molecular formula: C43H45K3N6O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  2. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 azide,Cy5 叠氮化物

Sulfo-Cyanine5 azide,Cy5 叠氮化物,用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide

标签：sulfo-Cyanine5,Cy5, Azides, Microscopy
货号 规格 价格 货期
A3330 1 mg 110.00$ in stock
B3330 5 mg 290.00$ in stock
C3330 10 mg 470.00$ in stock
D3330 25 mg 690.00$ in stock
E3330 50 mg 1270.00$ in stock
F3330 100 mg 1990.00$ in stock

Water-soluble Cyanine5 dye azide for Click chemistry. Bright and photostable dye with red fluorescence. The reagent has high water solubility. Due to high solubility and hydrophilicity, the dye can be used for labeling biomolecules in native, purely aqueous conditions.

This reagent, as opposed to competing products, is supplied as an alkaline metal salt and not triethylammonium salt. Therefore, it is a powder which is easy to handle and dispense.

Sulfo-Cyanine5 is an analog of Cy5®, a very popular fluorophore, therefore this reagent is compatible to a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes.

用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

与竞争产品不同，该试剂以碱金属盐而非三乙基铵盐的形式提供。 因此，它是一种易于处理和分配的粉末。

Sulfo-Cyanine5 是 Cy5® 的类似物，Cy5® 是一种非常流行的荧光团，因此该试剂与各种标准荧光仪器兼容，例如成像仪、读板机和显微镜。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide,Cy5 叠氮化物相关产品

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

General properties

Appearance: dark blue crystals 深蓝色晶体
Molecular weight: 762.98
Molecular formula: C35H43N6KO7S2
Solubility: very high in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution. doi: 10.1159/000519068
  2. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. bioRxiv, preprint. doi: 10.1101/2021.02.12.430891
  3. Toyonaga, T.; Keith, B.P.; Barrow, J.B.; Schaner, M.S.; Wolber, E.A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N.L.; Chaumont, N.; Sadiq, T.S.; Koruda, M.j.; Rahbar, R.; Furey, T.S.; Sethupathy, P.; Sheikh, S.Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohn’s disease. bioRxiv, preprint. doi: 10.1101/2020.02.21.960070
  4. Hinman, S.; Wang, Y.; Allbritton, N. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. ChemRxiv, preprint. doi: 10.26434/chemrxiv.9759605.v1
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3.5 azide,Cy3.5 叠氮化物

Sulfo-Cyanine3.5 azide,Cy3.5 叠氮化物,Sulfo-Cyanine3.5 是一种荧光染料，其吸收和发射光谱介于 Cy3 和 Cy5 之间。 由于其光谱特性，这种荧光团广泛用于 BRET 和 FRET 实验，既可作为供体对，也可作为受体。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine3.5 azide

Sulfo-Cyanine3.5 azide

标签：Azides, sulfo-Cyanine3.5,Cy3.5
货号 规格 价格 货期
A2330 1 mg 110.00$ in stock
B2330 5 mg 290.00$ in stock
C2330 10 mg 470.00$ in stock
D2330 25 mg 690.00$ in stock
E2330 50 mg 1270.00$ in stock
F2330 100 mg 1990.00$ in stock

Sulfo-Cyanine3.5 is a fluorescent dye with absorption and emission spectra between those of Cyanine3 and Cyanine5. Because of its spectral characteristics, this fluorophore is widely used in BRET and FRET experiments both as a pair donor and acceptor.

Sulfo-Cyanine3.5 is a sulfonated derivative of Cyanine3.5 dye because it contains four additional sulfo groups, which ensures high water solubility of the dye and its conjugates. This allows working with this reagent in aqueous solutions without adding organic solvents.

This reagent is an azide derivative of sulfo-Cyanine3.5 dye for Click Chemistry reactions. The azide group allows conjugating the fluorophore with molecules containing alkyne or cycloalkyne groups, including various biomolecules, small molecules, and polymers, using copper-catalyzed Click chemistry and copper-free spAAC reaction.

Sulfo-Cyanine3.5 是一种荧光染料，其吸收和发射光谱介于 Cy3 和 Cy5 之间。 由于其光谱特性，这种荧光团广泛用于 BRET 和 FRET 实验，既可作为供体对，也可作为受体。

Sulfo-Cyanine3.5 是 Cyanine3.5 染料的磺化衍生物，因为它含有四个额外的磺基，可确保染料及其结合物的高水溶性。 这允许在不添加有机溶剂的情况下在水溶液中使用该试剂。

该试剂是用于 Click Chemistry 反应的磺基-Cyanine3.5 染料的叠氮化物衍生物。 叠氮基允许使用铜催化的点击化学和无铜 spAAC 反应将荧光团与含有炔烃或环炔烃基团的分子（包括各种生物分子、小分子和聚合物）缀合。

Absorption and emission spectra of sulfo-Cyanine3.5

Sulfo-Cyanine3.5 azide

Sulfo-Cyanine3.5 azide,Cy3.5 叠氮化物相关产品

Sulfo-Cyanine3.5 NHS ester

Amine reactive activated ester of water soluble, sulfonated sulfo-Cyanine3.5 dye.

水溶性磺化磺化Cyanine3.5染料的胺活性活性酯。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性，推荐用于水环境中生物分子的标记。

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 959.2
Molecular weight: 1073.37
Molecular formula: C41H43N6K3O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 576
ε, L⋅mol−1⋅cm−1: 139000
Emission maximum, nm: 603
Fluorescence quantum yield: 0.11
CF260: 0.16
CF280: 0.17

Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide,Sulfo-Cyanine3 azide 是一种用于 Click Chemistry 的水溶性染料叠氮化物。 染料的吸光度和发射与 Cy3® 荧光团相同。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide

标签：Azides, Microscopy, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
A1330 1 mg 110.00$ in stock
B1330 5 mg 290.00$ in stock
C1330 10 mg 470.00$ in stock
D1330 25 mg 690.00$ in stock
E1330 50 mg 1270.00$ in stock
F1330 100 mg 1990.00$ in stock

Sulfo-Cyanine3 azide is a water-soluble dye azide for Click Chemistry. Absorbance and emission of the dye are identical to Cy3® fluorophore.

Brightness and photostability of fluorophore, together with high water solubility, makes this reagent an ideal choice for Click chemistry labeling of various molecules in aqueous phase.

Click reaction can be carried out in pure water without need to use organic co-solvent. The reagent is designed for the labeling of sensitive molecules such as proteins, and even intact biological objects.

Sulfo-Cyanine3 azide 是一种用于 Click Chemistry 的水溶性染料叠氮化物。 染料的吸光度和发射与 Cy3® 荧光团相同。

荧光团的亮度和光稳定性以及高水溶性使该试剂成为水相中各种分子的点击化学标记的理想选择。

点击反应可在纯水中进行，无需使用有机助溶剂。 该试剂设计用于标记蛋白质等敏感分子，甚至是完整的生物对象。

Sulfo-Cyanine3 absorbance and emission spectra

Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide相关产品

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: dark red crystals 暗红色晶体
Molecular weight: 736.94
CAS number: 2055138-89-9 (sodium salt), 1658416-54-6
Molecular formula: C33H41N6KO7S2
Solubility: soluble in water (0.62 M = 46 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献：

  1. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  2. Li, D.; Taylor, D.H.; van Wolfswinkel, J.C. PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation. Cell Reports, 2021, 37(1), 109776. doi: 10.1016/j.celrep.2021.109776
  3. Wang, J.; Li, T.; Wang, J.-L.; Xu, Z.; Meng, W.; Wu, Q.-F. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Reports, 2020, 33(11), 108495. doi: 10.1016/j.celrep.2020.108495
  4. Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
Cy® is a trademark of GE Healthcare.

ROX azide, 5- isomer,ROX 叠氮化物

ROX azide, 5- isomer,ROX 叠氮化物,ROX (rhodamine-X) 叠氮化物、固体材料和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 ROX 是一种发红光的罗丹明染料，具有高亮度和荧光量子产率。

  • Products
  • Reactive dyes
  • Dye azides
  • ROX azide, 5- isomer

ROX azide, 5- isomer

标签：ROX (Rhodamine X Rhodamine 101), Azides, Microscopy
货号 规格 价格 货期
11230 100 uL, 10 mM/DMSO 110.00$ in stock
31230 500 uL, 10 mM/DMSO 210.00$ in stock
41230 1 mL, 10 mM/DMSO 410.00$ in stock
A1230 1 mg 110.00$ in stock
B1230 5 mg 210.00$ in stock
C1230 10 mg 310.00$ in stock
D1230 25 mg 410.00$ in stock
E1230 50 mg 695.00$ in stock

ROX (rhodamine-X) azide, solid material, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. ROX is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield.

ROX (rhodamine-X) 叠氮化物、固体材料和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 ROX 是一种发红光的罗丹明染料，具有高亮度和荧光量子产率。

Pure 5-isomer.

Absorption and emission spectra of ROX dye

ROX azide, 5- isomer

ROX azide, 5- isomer,ROX 叠氮化物相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

ROX azide, 5- isomer Add this product to your cart and
get free express delivery

ROX NHS ester, 5-isomer

Activated NHS ester of ROX (rhodamine X or rhodamine 101), pure 5-isomer, for the labeling of amine groups of biomolecules.

ROX 的活化 NHS 酯（罗丹明 X 或罗丹明 101），纯 5-异构体，用于标记生物分子的胺基。

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

General properties

Appearance: dark crimson powder / red solution
Molecular weight: 616.71
CAS number: 2628213-67-0
Molecular formula: C36H36N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.0

相关文献：

  1. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
  2. Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
  3. Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
  4. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145

R6G azide, 5-isomer

R6G azide, 5-isomer,R6G（罗丹明 6G）是一种发黄光的呫吨染料。 它以前已用于 DNA 测序。 现在这种染料常用于 qPCR。 这是 R6G 的纯 5-异构体，带有叠氮基。

  • Products
  • Reactive dyes
  • Dye azides
  • R6G azide, 5-isomer

R6G azide, 5-isomer

标签：Azides, R6G,5-isomer
货号 规格 价格 货期
A4430 1 mg 110.00$ in stock
B4430 5 mg 210.00$ in stock
C4430 10 mg 310.00$ in stock
D4430 25 mg 410.00$ in stock
E4430 50 mg 695.00$ in stock

R6G (rhodamine 6G) is a yellow emitting xanthene dye. It has been used for DNA sequencing before. Now this dye is often used for qPCR. This is a pure 5-isomer of R6G with azide group.

R6G（罗丹明 6G）是一种发黄光的呫吨染料。 它以前已用于 DNA 测序。 现在这种染料常用于 qPCR。 这是 R6G 的纯 5-异构体，带有叠氮基。

Absorption and emission spectra for 5-R6G

R6G azide, 5-isomer

R6G azide, 5-isomer相关产品

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cyanine5 活化酯，用于标记蛋白质、肽和其他分子。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cy5.5 染料衍生物。

General properties

Appearance: orange to brown powder 橙色至棕色粉末
Mass spec M+ increment: 540.3
Molecular weight: 540.61
Molecular formula: C30H32N6O4
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 519
ε, L⋅mol−1⋅cm−1: 116000
Emission maximum, nm: 546
Fluorescence quantum yield: 0.95
CF260: 0.18
CF280: 0.17

Pyrene azide 2,叠氮修饰荧光染料,pyrene azide染料

Pyrene azide 2,叠氮修饰荧光染料,pyrene azide染料,这种pyrene 叠氮化物是pyrene 乙酸的衍生物。 含有三甘醇接头。也可以使用具有较短接头的替代pyrene 叠氮化物。 在那里可以找到荧光团的详细描述。

  • Products
  • Reactive dyes
  • Dye azides
  • Pyrene azide 2

Pyrene azide 2

标签：Azides, Pyrene,Pyrene azide 2,叠氮修饰荧光染料,pyrene azide染料
货号 规格 价格 货期
A2530 1 mg 110.00$ in stock
B2530 5 mg 210.00$ in stock
C2530 10 mg 310.00$ in stock
D2530 25 mg 410.00$ in stock
E2530 50 mg 695.00$ in stock

This pyrene azide is a derivative of pyreneacetic acid. Contains triethylene glycol linker.

An alternative pyrene azide with a shorter linker is also available. A detailed description of the fluorophore can be found there.

这种pyrene 叠氮化物是pyrene 乙酸的衍生物。 含有三甘醇接头。

也可以使用具有较短接头的替代pyrene 叠氮化物。 在那里可以找到荧光团的详细描述。

Absorption and emission spectra of pyrene fluorophore

Pyrene azide 2

Pyrene azide 2,叠氮修饰荧光染料,pyrene azide染料相关产品

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

Sulfo-Cyanine5 azide

Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cyanine5 荧光染料叠氮化物。

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cyanine3 染料叠氮化物。

General properties

Appearance: yellowish solid  淡黄色固体
Molecular weight: 416.47
CAS number: 1807512-45-3
Molecular formula: C24H24N4O3
Solubility: good solubility in chloroform, dichloromethane, moderate solubility in DMSO, DMF, acetonitrile
Quality control: NMR 1H (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397

相关文献：

  1. Wanat, P.; Walczak, S.; Wojtczak, B.A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Organic Letters, 2015, 17(12), 3062–3065. doi: 10.1021/acs.orglett.5b01346

Pyrene azide 1,叠氮修饰荧光染料,pyrene azide染料

Pyrene azide 1,叠氮修饰荧光染料,pyrene azide染料,Pyrene 是一种具有强短波荧光的多环芳烃。 与其他荧光染料不同，多环芳烃是对微环境具有强敏感性的荧光探针。 因此，它的荧光在极性和非极性环境中是不同的。 还可以观察到其他效果。

  • Products
  • Reactive dyes
  • Dye azides
  • Pyrene azide 1

Pyrene azide 1

标签：Azides, Pyrene
货号 规格 价格 货期
A1530 1 mg 110.00$ in stock
B1530 5 mg 210.00$ in stock
C1530 10 mg 310.00$ in stock
D1530 25 mg 410.00$ in stock
E1530 50 mg 695.00$ in stock

Pyrene is a polyaromatic hydrocarbon with strong short-wavelength fluorescence. Unlike other fluorescent dyes, polyaromatic hydrocarbons are fluorescent probes with strong sensitivity to microenvironment. Thus, its fluorescence is different in polar, and nonpolar environments. Other effects can also be observed.

When two pyrenes are in close proximity, they form excimers. Excimer formation can be easily observed, and quantitatively estimated using fluorescent spectra.

Pyrene azide is a reagent for easy pyrene Click Chemistry labeling of any alkyne-bearing molecule. It allows to turn any molecule into pyrene-bearing probe.

This azide contains hydrophilic triethyleneglycol linker to mitigate intrinsic pyrene hydrophobicity, and facilitate attachment to biomolecules in aqueous solutions.

Another pyrene azide for Click Chemistry labeling is also available: Pyrene azide 2.

Pyrene 是一种具有强短波荧光的多环芳烃。 与其他荧光染料不同，多环芳烃是对微环境具有强敏感性的荧光探针。 因此，它的荧光在极性和非极性环境中是不同的。 还可以观察到其他效果。

当两个Pyrene 靠近时，它们会形成准分子。 准分子的形成可以很容易地观察到，并使用荧光光谱进行定量估计。

Pyrene azide 是一种试剂，可轻松标记任何含炔烃分子的芘 Click Chemistry。 它允许将任何分子变成带有芘的探针。

这种叠氮化物含有亲水性三甘醇接头，可减轻Pyrene 固有的疏水性，并促进水溶液中生物分子的附着。

另一种用于 Click Chemistry 标记的Pyrene 叠氮化物也可提供：Pyrene azide 2。

Absorption and emission spectra of pyrene fluorophore

Pyrene azide 1

Pyrene azide 1,叠氮修饰荧光染料,pyrene azide染料相关产品

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cyanine5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

General properties

Appearance: yellowish solid 淡黄色固体
Molecular weight: 402.45
CAS number: 2135330-58-2
Molecular formula: C23H22N4O3
Solubility: soluble in dichloromethane, chloroform, moderately soluble in DMSO, DMF, acetonitrile
Quality control: NMR 1H (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397

PEP azide,叠氮修饰荧光染料

PEP azide,Phenylethynylpyrene (PEP) 荧光团是一种对微环境具有高度敏感性的多环芳烃标记物。 与芘类似，PEP 染料很容易形成准分子。 然而，PEP 荧光更红移

  • Products
  • Reactive dyes
  • Dye azides
  • PEP azide

PEP azide

标签：Azides, Phenylethynyl-pyrene (PEP),叠氮修饰荧光染料
货号 规格 价格 货期
A4530 1 mg 110.00$ in stock
B4530 5 mg 210.00$ in stock
C4530 10 mg 310.00$ in stock
D4530 25 mg 410.00$ in stock
E4530 50 mg 695.00$ in stock

Phenylethynylpyrene (PEP) fluorophore is a polyaromatic hydrocarbon label with high sensitivity to microenvironment. Similarly to pyrene, PEP dye readily forms excimers. However, PEP fluorescence is more red-shifted

PEP can be used as microenvironment probe, and as a label for assays based on excimer formation.

This reagent contains triethyleneglycol linker to facilitate dissolution of non-polar PEP dye in organo-aqueous labeling reaction mixtures. With this azide, and Click Chemistry, it is easy to turn any molecule bearing alkyne into PEP-labeled probe.

Phenylethynylpyrene (PEP) 荧光团是一种对微环境具有高度敏感性的多环芳烃标记物。 与芘类似，PEP 染料很容易形成准分子。 然而，PEP 荧光更红移

PEP 可用作微环境探针，并用作基于准分子形成的分析的标记。

该试剂含有三甘醇接头，以促进非极性 PEP 染料在有机水标记反应混合物中的溶解。 使用这种叠氮化物和 Click Chemistry，很容易将任何带有炔烃的分子转化为 PEP 标记的探针。

Spectra of PEP (phenylethynylpyrene) in ethanol

PEP azide

PEP azide叠氮修饰荧光染料相关产品

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素（一种众所周知的亲和探针）进行点击化学标记的试剂。

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

General properties

Appearance: off white / yellowish solid 灰白色/淡黄色固体
Molecular weight: 544.64
CAS number: 1807521-02-3
Molecular formula: C34H32N4O3
Solubility: soluble in dichloromethane, chloroform, moderately soluble in DMSO, DMF, acetonitrile
Quality control: NMR 1H (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 293; 362; 384
Emission maximum, nm: 389

相关文献：

  1. Taskova, M.; Astakhova, K. Fluorescent Oligonucleotides with Bis(prop-2-yn-1-yloxy)butane-1,3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids. Bioconjugate Chemistry, 2019, 30(12), 3007–3012. doi: 10.1021/acs.bioconjchem.9b00746