标签： alk

A83-01 产品英文简述: A83-01 50mg TGF-β家族

产品英文名称:A83-01
产品中文名称:A83-01

订购： 

A83-01 产品英文简述:
A selective inhibitor of ALK-4 （Activin/Nodal receptor）, ALK-5 （TGF-β type I receptor）, and ALK-7 （nodal receptor）. Only weakly inhibits ALK-1, -2, -3, and -6. 3-（6-METHYLPYRIDIN-2-YL）-1-PHENYLTHIOCARBAMOYL-4-QUINOLIN-4-YLPYRAZOLE

Ref: Tojo, M., et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 96: 791-800, 2005.

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: Not determined.

_A83-01 10mg TGF-β家族

产品英文名称:A83-01
产品中文名称:A83-01

订购： 

A83-01 产品英文简述:
A selective inhibitor of ALK-4 （Activin/Nodal receptor）, ALK-5 （TGF-β type I receptor）, and ALK-7 （nodal receptor）. Only weakly inhibits ALK-1, -2, -3, and -6. 3-（6-METHYLPYRIDIN-2-YL）-1-PHENYLTHIOCARBAMOYL-4-QUINOLIN-4-YLPYRAZOLE

Ref: Tojo, M., et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 96: 791-800, 2005.

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: Not determined.

A83-01 产品英文简述: A83-01 2mg TGF-β家族

产品英文名称:A83-01
产品中文名称:A83-01

 

A83-01 产品英文简述:
A selective inhibitor of ALK-4 （Activin/Nodal receptor）, ALK-5 （TGF-β type I receptor）, and ALK-7 （nodal receptor）. Only weakly inhibits ALK-1, -2, -3, and -6. 3-（6-METHYLPYRIDIN-2-YL）-1-PHENYLTHIOCARBAMOYL-4-QUINOLIN-4-YLPYRAZOLE

Ref: Tojo, M., et al. The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta. Cancer Sci. 96: 791-800, 2005.

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: Not determined.

ALK-5 产品英文简述: ALK-5 Inhibitor 50mg TGF-β家族

产品英文名称:ALK-5 Inhibitor
产品中文名称:ALK-5 抑制剂

 

ALK-5 产品英文简述:
A selective inhibitor of ALK5 （TGF-beta type I receptor）. It has also been shown that this compound can replace Sox2 when reprogramming cells to iPS cells. 2-（3-（6-METHYLPYRIDIN-2-YL）-1H-PYRAZOL-4-YL）-1,5-NAPHTHYRIDINE

Ref: Gellibert, F., et al. （2004） Identification of 1, 5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J Med Chem 47: 4494-4506. Ichida, J.K., et al. （2009） A small-molecule inhibitor of Tgf-beta signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5: 491-503

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity :Not determined.

ALK-5 产品英文简述: ALK-5 Inhibitor 10mg TGF-β家族

产品英文名称:ALK-5 Inhibitor
产品中文名称:ALK-5 抑制剂

 

ALK-5 产品英文简述:
A selective inhibitor of ALK5 （TGF-beta type I receptor）. It has also been shown that this compound can replace Sox2 when reprogramming cells to iPS cells. 2-（3-（6-METHYLPYRIDIN-2-YL）-1H-PYRAZOL-4-YL）-1,5-NAPHTHYRIDINE

Ref: Gellibert, F., et al. （2004） Identification of 1, 5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J Med Chem 47: 4494-4506. Ichida, J.K., et al. （2009） A small-molecule inhibitor of Tgf-beta signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5: 491-503

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity :Not determined.

ALK-5 产品英文简述: ALK-5 Inhibitor 2mg TGF-β家族

产品英文名称:ALK-5 Inhibitor
产品中文名称:ALK-5 抑制剂

 

ALK-5 产品英文简述:
A selective inhibitor of ALK5 （TGF-beta type I receptor）. It has also been shown that this compound can replace Sox2 when reprogramming cells to iPS cells. 2-（3-（6-METHYLPYRIDIN-2-YL）-1H-PYRAZOL-4-YL）-1,5-NAPHTHYRIDINE

Ref: Gellibert, F., et al. （2004） Identification of 1, 5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J Med Chem 47: 4494-4506. Ichida, J.K., et al. （2009） A small-molecule inhibitor of Tgf-beta signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5: 491-503

Purity: Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity :Not determined.