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MIP 4 Human, His
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Macrophage Inflammatory protein-4 Human Recombinant, His-Tag
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CHM-339
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Catalogue number
CHM-339
Synonyms
Small inducible cytokine A18, CCL18, Macrophage inflammatory protein 4, MIP-4, Pulmonary and activation-regulated chemokine, CC chemokine PARC, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, Dendritic cell chemokine 1, DC-CK1, chemokine ligand 18, CKb7, PARC, AMAC1, DCCK1, SCYA18.
Introduction
Chemokine ligand 18 is a small cytokine belonging to the CC chemokine family that was previously called PARC . CCL18 is approximately 60% identical in amino acid sequence to CCL3. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and non activated lymphocytes. The gene for human CCL18 contains three exons and is located on chromosome 17.
趋化因子配体 18 是一种小细胞因子,属于 CC 趋化因子家族,以前称为 PARC。 CCL18 在氨基酸序列上与 CCL3 有大约 60% 的相同性。 它在肺中以高水平表达,而在某些淋巴组织(如淋巴结)中表达水平较低,并且对活化的 T 细胞和未活化的淋巴细胞具有趋化性。 人类 CCL18 的基因包含三个外显子,位于第 17 号染色体上。
Description
MIP-4 Human Recombinant fused with a 25 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 93 amino acids and having a molecular mass of 10.4kDa. The MIP-4 is purified by proprietary chromatographic techniques.
MIP-4 Human Recombinant 在 N 末端融合了 25 个氨基酸的 His 标签,在大肠杆菌中产生,是一条含有 93 个氨基酸且分子量为 10.4kDa 的单一非糖基化多肽链。 MIP-4 通过专有的色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The MIP-4 solution contains 10mM Sodium Citrate pH3.5 and 10% Glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQVGTN KELCCLVYTS WQIPQKFIVD YSETSPQCPK PGVILLTKRG RQICADPNKK WVQKYISDLK LNA.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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