ProSpec,MIP 3b Human T7 CHM-374,巨噬细胞炎症蛋白 3 人重组体T7 CHM-374

ProSpec,MIP 3b Human T7 CHM-374,巨噬细胞炎症蛋白 3 人重组体T7 CHM-374,趋化因子配体 19 是一种小细胞因子,属于 CC 趋化因子家族,也称为 EBI1 配体趋化因子和巨噬细胞炎症蛋白-3-β。

  • MIP 3b Human, T7

  • Macrophage Inflammatory protein-3 Human Recombinant, T7 Tag
  • CHM-374

Catalogue number

CHM-374

Synonyms

Small inducible cytokine A19, CCL19, Macrophage inflammatory protein 3 beta, MIP-3- beta, EBI1-ligand chemokine, ELC, Beta chemokine exodus-3, CK beta-11, chemokine ligand 19, CKb11, MIP3B, MIP-3b, SCYA19, MGC34433, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1-ligand chemokine.

Introduction

Chemokine ligand 19 is a small cytokine belonging to the CC chemokine family that is also known as EBI1 ligand chemokine and macrophage inflammatory protein-3-beta . CCL19 is expressed abundantly in thymus and lymph nodes, with moderate levels in trachea and colon and low levels in stomach, small intestine, lung, kidney and spleen. The gene for CCL19 is located on human chromosome 9. This chemokine elicits its effects on its target cells by binding to the chemokine receptor chemokine receptor CCR7. It attracts certain cells of the immune system, including dendritic cells and antigen-engaged B cells.
趋化因子配体 19 是一种小细胞因子,属于 CC 趋化因子家族,也称为 EBI1 配体趋化因子和巨噬细胞炎症蛋白-3-β。 CCL19 在胸腺和淋巴结中大量表达,在气管和结肠中表达水平适中,在胃、小肠、肺、肾和脾脏中表达水平较低。 CCL19 的基因位于人类第 9 号染色体上。该趋化因子通过与趋化因子受体趋化因子受体 CCR7 结合而对其靶细胞产生影响。 它吸引免疫系统的某些细胞,包括树突状细胞和抗原结合的 B 细胞。

Description

MIP3b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.4kDa.
MIP3b is fused to a 16 amino acid T7-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 MIP3b Human Recombinant 是一条单一的、非糖基化的多肽链,含有 93 个氨基酸,分子量为 10.4kDa。
MIP3b 在 N 末端与 16 个氨基酸的 T7 标签融合,并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

MIP3b protein solution containing Phosphate Buffered Saline pH7.4 and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MASMTGGQQM GRGSHMGTND AEDCCLSVTQ KPIPGYIVRN FHYLLIKDGC RVPAVVFTTL RGRQLCAPPD QPWVERIIQR LQRTSAKMKR RSS.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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