标签： 巨噬细胞炎症蛋白-1 γ 小鼠重组CHM-257

ProSpec,MIP-1 Gamma Mouse CHM-257,巨噬细胞炎症蛋白-1 γ 小鼠重组CHM-257

ProSpec,MIP-1 Gamma Mouse CHM-257,巨噬细胞炎症蛋白-1 γ 小鼠重组CHM-257,在大肠杆菌中产生的 MIP-1 gamma Mouse Recombinant 是一种单一的、非糖基化的多肽链，含有 101 个氨基酸，分子量为 11.6 kDa。 MIP-1 gamma 采用专有色谱技术进行纯化。

  • MIP-1 Gamma Mouse

  • Macrophage Inflammatory Protein-1 Gamma Mouse Recombinant
  • CHM-257

Catalogue number

CHM-257

Synonyms

CCL9/10, MRP2, CCF18.

Introduction

Mouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals through the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines.
与大鼠相比，小鼠 MIP-1 γ 的氨基酸组成有 75% 相同。 MIP-1 γ 是一种 CC 趋化因子，位于鼠血和广泛的鼠组织中，但没有确定的人类同源物。 MIP-1 伽马信号通过 CCR1 受体。 MIP-1 γ 趋化嗜中性粒细胞并且还抑制骨髓髓系未成熟祖细胞的集落形成。 MIP-1 γ 具有六个半胱氨酸，包括存在于 CC 趋化因子中的四个高度保守的半胱氨酸残基。

Description

MIP-1 gamma Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 101 amino acids and having a molecular mass of 11.6 kDa. The MIP-1 gamma is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 MIP-1 gamma Mouse Recombinant 是一种单一的、非糖基化的多肽链，含有 101 个氨基酸，分子量为 11.6 kDa。 MIP-1 gamma 采用专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The MIP-1 gamma was lyophilized from 1xPBS solution pH-7.4.

Solubility

It is recommended to reconstitute the lyophilized MIP-1 gamma in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized MIP-1 gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL9/10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Biological Activity

Defined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10 ng/ml, corresponding to a Specific Activity of 10,000-100,000IU/mg.

Amino acid sequence

QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.