标签： 叠氮化物

TAMRA azide, 6-isomer,叠氮化物,Dye azides

TAMRA azide, 6-isomer,叠氮化物,Dye azides,四甲基罗丹明 (TAMRA) 是一种具有橙色发射光的呫吨染料。 该染料是 FAM 的 FRET 受体，有时用作它的猝灭剂。

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  • TAMRA azide, 6-isomer

TAMRA azide, 6-isomer

标签：Azides, TAMRA (TMR, tetramethylrhodamine),叠氮化物,Dye azides
货号 规格 价格 货期
A8130 1 mg 110.00$ in stock
B8130 5 mg 180.00$ in stock
C8130 10 mg 310.00$ in stock
D8130 25 mg 410.00$ in stock
E8130 50 mg 695.00$ in stock
F8130 100 mg 1190.00$ in stock

Tetramethylrhodamine (TAMRA) is a xanthene dye with orange emission. The dye is a FRET acceptor for FAM, and sometimes used as a quencher for it.

Like other xanthenes, TAMRA exists as two isomers (5- and 6-), which have very similar spectral properties. This is an azide derivative of 6-isomer of TAMRA. The azide can be conjugated with terminal alkynes using copper-catalyzed Click chemistry, or with cycloalkynes with copper-free strain promoted alkyne azide cycloaddition (spAAc) reaction.

四甲基罗丹明 (TAMRA) 是一种具有橙色发射光的呫吨染料。 该染料是 FAM 的 FRET 受体，有时用作它的猝灭剂。

与其他呫吨一样，TAMRA 以两种异构体（5-和 6-）存在，它们具有非常相似的光谱特性。 这是TAMRA 6-异构体的叠氮化物衍生物。 叠氮化物可以使用铜催化的点击化学与末端炔烃缀合，或与环炔烃缀合，无铜应变促进炔烃叠氮化物环加成 (spAAc) 反应。

TAMRA azide, 6-isomer相关产品

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: violet solid / solution 紫色固体/溶液
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 1192590-89-8
Molecular formula: C28H28N6O4
Solubility: Good in DMF, DMSO, alcohols, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  2. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  3. Chen, X.; Xu, J.; Wong, N.-K.; Zhong, S.; Yang, M.; Liu, Z.; Lu, Y.; Li, W.; Zhou, Y. Chemoproteomic profiling of cobalamin-independent methionine synthases in plant with a covalent probe. Journal of Agricultural and Food Chemistry, 2020, 68(30), 8050–8056. doi: 10.1021/acs.jafc.0c03301
  4. Xu, Y.; Deng, Z.; Shi, Y.; Chen, X.; Xu, J.; Zhong, S.; Xiao, Y.; Wong, N.-K.; Zhou, Y. Molecular Imaging and In Situ Quantitative Profiling of Fatty Acid Synthase with a Chemical Probe. Analytical Chemistry, 2020, 92(6), 4419–4426. doi: 10.1021/acs.analchem.9b05327

TAMRA azide, 5-isomer,叠氮化物,Dye azides

TAMRA azide, 5-isomer,叠氮化物,Dye azides,TAMRA（TMR，四甲基罗丹明）叠氮化物、固体化合物和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 纯5-异构体。

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  • Reactive dyes
  • Dye azides
  • TAMRA azide, 5-isomer

TAMRA azide, 5-isomer

标签：Azides, TAMRA (TMR, tetramethylrhodamine),叠氮化物,Dye azides
货号 规格 价格 货期
A7130 1 mg 110.00$ in stock
B7130 5 mg 180.00$ 5 days
C7130 10 mg 310.00$ in stock
D7130 25 mg 410.00$ in stock
E7130 50 mg 695.00$ in stock
F7130 100 mg 1190.00$ in stock

TAMRA (TMR, tetramethylrhodamine) azide, solid compound, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. Pure 5-isomer.

TAMRA is often used as FRET acceptor for FAM fluorophore.

TAMRA（TMR，四甲基罗丹明）叠氮化物、固体化合物和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 纯5-异构体。

TAMRA 通常用作 FAM 荧光团的 FRET 受体。

Can replace DyLight 549.

Absorption and emission spectra of 5-TAMRA

TAMRA azide, 5-isomer

TAMRA azide, 5-isomer,叠氮化物,Dye azides相关产品

Sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3 analog.

Sulfo-Cyanine3 的水溶性硫醇反应性衍生物，一种 Cy3 类似物。

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

General properties

Appearance: violet solid / solution 紫色固体/溶液
Mass spec M+ increment: 512.2
Molecular weight: 512.56
CAS number: 825651-66-9
Molecular formula: C28H28N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  2. Puthenveetil, R.; Lun, C.M.; Murphy, R.E.; Healy, L.B.; Vilmen, G.; Christenson, E.T.; Freed, E.O.; Banerjee, A. S-acylation of SARS-CoV-2 Spike Protein: Mechanistic Dissection, In Vitro Reconstitution and Role in Viral Infectivity. Journal of Biological Chemistry, 2021, 297(4), 101112. doi: 10.1016/j.jbc.2021.101112
  3. Seneviratne, U.; Huang, Z.; Am Ende, C.W.; Butler, T.W.; Cleary, L.; Dresselhaus, E.; Evrard, E.; Fisher, E.L.; Green, M.E.; Helal, C.J.; Humphrey, J.M.; Lanyon, L.F.; Marconi, M.; Mukherjee, P.; Sciabola, S.; Steppan, C.M.; Sylvain, E.K.; Tuttle, J.B.; Verhoest, P.R.; Wager, T.T.; Xie, L.; Ramaswamy, G.; Johnson, D.S.; Pettersson, M. Photoaffinity Labeling and Quantitative Chemical Proteomics Identify LXRβ as the Functional Target of Enhancers of Astrocytic apoE. Cell Chemical Biology, 2021, 28(2), 148–157.e7. doi: 10.1016/j.chembiol.2020.09.002
  4. Zhang, M.; Zhou, L.; Xu, Y.; Yang, M.; Xu, Y.; Komaniecki, G.P.; Kosciuk, T.; Chen, X.; Lu, X.; Zou, X.; Linder, M.E.; Lin, H. A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis. Nature, 2020, 586(7829), 434–439. doi: 10.1038/s41586-020-2799-2

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides,Sulfo-Cyanine7.5 是一种七甲炔花青染料，适用于光谱的近红外区域，具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG（吲哚菁绿），甚至被批准用于人体血管造影。 然而，与 ICG 相比，磺基-Cyanine7.5 具有显着提高的荧光量子产率，这是由于用三亚甲基桥加强的崎岖多甲炔链。

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  • Reactive dyes
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  • Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide

标签：Azides, Near infrared (NIR) imaging, sulfo-Cyanine7.5,Cy7.5,叠氮化物,Dye azides
货号 规格 价格 货期
A6330 1 mg 110.00$ in stock
B6330 5 mg 290.00$ in stock
C6330 10 mg 470.00$ in stock
D6330 25 mg 690.00$ in stock
E6330 50 mg 1270.00$ in stock
F6330 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a heptamethyne cyanine dye for the near infrared region of the spectrum, which is very hydrophilic, and water soluble. The fluorophore resembles ICG (indocyanine green) that has a long history of in vivo use, and is even approved for human angiography. However, compared to ICG, sulfo-Cyanine7.5 has a significantly improved fluorescence quantum yield due to the rugged polymethine chain reinforced with trimethylene bridge.

Sulfo-Cyanine7.5 is available as a number of reactive derivatives. This azide can be used for the easy labeling of various biomolecules by copper-catalyzed or copper free Click chemistry.

Sulfo-Cyanine7.5 是一种七甲炔花青染料，适用于光谱的近红外区域，具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG（吲哚菁绿），甚至被批准用于人体血管造影。 然而，与 ICG 相比，磺基-Cyanine7.5 具有显着提高的荧光量子产率，这是由于用三亚甲基桥加强的崎岖多甲炔链。

Sulfo-Cyanine7.5 可作为许多反应性衍生物使用。 这种叠氮化物可用于通过铜催化或无铜点击化学轻松标记各种生物分子。

Absorption and emission spectra of sulfo-Cyanine7.5 fluorophore

Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性，推荐用于水环境中生物分子的标记。

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 1050.3
Molecular weight: 1165.51
Molecular formula: C48H51N6K3O13S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09