分类： 活性染料 Reactive dyes

用于标记生物分子的活性染料。
Reactive dyes for the labeling of biomolecules.

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide,Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG（吲哚菁绿）相似的光谱特性，但具有更高的荧光量子产率。 因此，这种荧光团是体内成像的理想选择。

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  • Cyanine7.5 hydrazide

Cyanine7.5 hydrazide

标签：Cyanine7.5,Cy7.5, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
16070 1 mg 110.00$ in stock
26070 5 mg 210.00$ in stock
46070 25 mg 410.00$ in stock
56070 50 mg 695.00$ in stock
66070 100 mg 1190.00$ in stock

A carbonyl-reactive hydrazide derivative of Cyanine7.5 near infrared (NIR) fluorophore. This dye has similar spectral properties with ICG (indocyanine green), but has a higher quantum yield of fluorescence. Hence, this fluorophore is ideal for in vivo imaging.

This is a carbonyl-reactive dye which is particularly useful for the labeling of antibodies after periodate oxidation. It also labels other carbonyl compounds (aldehydes and ketones), for example, many saccharides.

Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG（吲哚菁绿）相似的光谱特性，但具有更高的荧光量子产率。 因此，这种荧光团是体内成像的理想选择。

这是一种羰基反应性染料，特别适用于高碘酸氧化后的抗体标记。 它还标记其他羰基化合物（醛和酮），例如许多糖类。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide相关产品

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 DBCO

Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for Copper free Click chemistry.

Cy5.5 是一种远红/近红外发射染料，可用于生物成像研究。 Cy5.5 DBCO 是具有环炔部分的染料衍生物，用于无铜点击化学。

TAMRA hydrazide, 6-isomer

6-TAMRA azide is a carbonyl reactive hydrazide derivative of tetramethylrhodamine (TAMRA) fluorophore.

6-TAMRA azide 是四甲基罗丹明 (TAMRA) 荧光团的羰基反应性酰肼衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 644.4
Molecular weight: 735.82
Molecular formula: C45H52Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献：

  1. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445
Cy® is a trademark of GE Healthcare.

Cyanine7 hydrazide

Cyanine7 hydrazide,Cy7 的酰肼衍生物，一种 NIR 荧光染料，是 Cy7® 的类似物。这种七次甲基荧光团包含一个六元环，使聚次甲基链刚性化，与母体结构相比，量子产率提高了 20%。

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  • Reactive dyes
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  • Cyanine7 hydrazide

Cyanine7 hydrazide

标签：Cyanine7,Cy7, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
15070 1 mg 110.00$ in stock
25070 5 mg 210.00$ in stock
45070 25 mg 410.00$ in stock
55070 50 mg 695.00$ in stock
65070 100 mg 1190.00$ in stock

Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.

This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.

Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.

Cy7 的酰肼衍生物，一种 NIR 荧光染料，是 Cy7® 的类似物。

这种七次甲基荧光团包含一个六元环，使聚次甲基链刚性化，与母体结构相比，量子产率提高了 20%。

酰肼与醛类和酮类反应迅速而平稳，产生稳定的腙产物。 该反应也有利于高碘酸氧化后糖蛋白的标记。

Cyanine7 absorbance and emission spectra

Cyanine7 hydrazide

Cyanine7 hydrazide相关产品

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 544.8
Molecular weight: 635.70
CAS number: 2183440-61-9 (without anion)
Molecular formula: C37H48Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
Cy® is a trademark of GE Healthcare.

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide,Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

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  • Cyanine5.5 hydrazide

Cyanine5.5 hydrazide

标签：Cyanine5.5, Cy5.5,Hydrazides, Microscopy
货号 规格 价格 货期
17070 1 mg 110.00$ in stock
27070 5 mg 210.00$ in stock
47070 25 mg 410.00$ in stock
57070 50 mg 695.00$ in stock
67070 100 mg 1190.00$ in stock

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.

Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

生物分子中的羰基可以在氧化应激或蛋白质脱氨基后自发形成。或者，醛基可以通过糖蛋白（例如抗体）的糖残基的高碘酸氧化特异性地产生。抗体可被高碘酸钠氧化，并用Cyanine5.5酰肼标记，形成Cyanine5.5标记的抗体。由于抗体中的糖残基远离可变的表位结合位点，因此该方法特别适用于标记抗体。

Cy5.5 是一种近红外荧光团，是 Cy5.5® 的类似物。它特别适用于需要低荧光背景的应用。染料的吸收和发射波长表现出显着的组织穿透性，因此 Cy5.5 适用于体内近红外成像应用。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

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FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

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Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

Cyanine5.5 hydrazide Add this product to your cart and
get free express delivery

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 669.73
Molecular formula: C40H46Cl2N4O
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
Cy® is a trademark of GE Healthcare.

Cyanine5 hydrazide

Cyanine5 hydrazide,Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

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  • Cyanine5 hydrazide

Cyanine5 hydrazide

标签: Cyanine5, Cy5,Hydrazides, Microscopy
货号 规格 价格 货期
13070 1 mg 110.00$ in stock
23070 5 mg 210.00$ in stock
43070 25 mg 410.00$ in stock
53070 50 mg 695.00$ in stock
63070 100 mg 1190.00$ in stock

Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.

This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.

Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, DyLight 649 dyes.

Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。

这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

Cyanine5 酰肼替代羰基反应性 Cy5®、DyLight 649 染料。

Cy5 absorbance and emission spectra

Cyanine5 hydrazide

Cyanine5 hydrazide相关产品

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.

荧光素 (FAM) 的环辛炔衍生物，用于与叠氮化物的无铜点击化学反应。 含有纯6-异构体的荧光素。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cyanine5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 569.61
CAS number: 1427705-31-4
Molecular formula: C32H42Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  2. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  4. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
Cy® is a trademark of Cytiva.

Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide,Boc 保护的 Cy5 酰肼活性染料，用于标记醛和酮。Cyanine5 Boc-hydrazide,Cy5

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  • Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide

货号 规格 价格 货期
130A0 1 mg 110.00$ in stock
230A0 5 mg 210.00$ 5 days
430A0 25 mg 410.00$ 5 days
530A0 50 mg 695.00$ in stock
630A0 100 mg 1190.00$ 5 days

Boc-protected Cyanine5 hydrazide reactive dye for the labeling of aldehydes and ketones.

Boc- (tert-butoxycarbonyl) protective group can be removed with trifluoroacetic acid, or other strong acid. Reactive hydrazide is formed, which can then couple with various carbonyl groups yielding Cyanine5-labeled molecules.

Boc 保护的 Cy5 酰肼活性染料，用于标记醛和酮。

Boc-（叔丁氧羰基）保护基可以用三氟乙酸或其他强酸去除。 形成反应性酰肼，然后可以与各种羰基偶联，产生花青 5 标记的分子。

Cyanine5 absorbance and emission spectra

Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide相关产品

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.

用于 NHS 酯标记的干燥高纯度无胺溶剂。

Cyanine3 NHS ester minimal dye

Cyanine3 minimal dye for protein labeling.

用于蛋白质标记的 Cyanine3 最小染料。

Cyanine5 NHS ester minimal dye

Cy5 NHS ester minimal dye for protein labeling.

Cy5 NHS 酯最小染料用于蛋白质标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 633.26
Molecular formula: C37H49ClN4O3
Solubility: good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04
Cy® is a trademark of GE Healthcare.

Cyanine3 hydrazide

Cyanine3 hydrazide,Cy3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

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  • Cyanine3 hydrazide

Cyanine3 hydrazide

标签：Cyanine3,Cy3, Hydrazides, Microscopy
货号 规格 价格 货期
11070 1 mg 110.00$ in stock
21070 5 mg 210.00$ in stock
41070 25 mg 410.00$ in stock
51070 50 mg 695.00$ in stock
61070 100 mg 1190.00$ in stock

Cyanine3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.

This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.

Cyanine3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

该试剂可以标记各种含羰基分子，例如高碘酸氧化后的抗体和其他糖蛋白、经历氧化应激或脱氨基作用的蛋白质或还原糖。 Cyanine3 与许多荧光仪器兼容。

Cyanine3 absorbance and emission spectra

Cyanine3 hydrazide

Cyanine3 hydrazide相关产品

BDP TR hydrazide

BDP TR hydrazide for the labeling of carbonyl compounds with BDP TR, a borondipyrromethene matching ROX channel.

BDP TR 酰肼，用于用 BDP TR 标记羰基化合物，BDP TR 是一种匹配 ROX 通道的硼二吡咯亚甲基。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: red powder 红色粉末
Molecular weight: 543.57
Molecular formula: C30H40Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  2. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  3. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  4. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
Cy® is a trademark of GE Healthcare.

BDP TR hydrazide

BDP TR hydrazide,Hydrazides, BDP TR,BDP TR 是一种用于 ROX 通道的硼二吡咯 (BODIPY®) 染料。 该化合物是一种酰肼反应性衍生物，可用于用 BDP TR 标记醛和酮。

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  • BDP TR hydrazide

BDP TR hydrazide

标签：Hydrazides, BDP TR
货号 规格 价格 货期
13470 1 mg 110.00$ in stock
23470 5 mg 210.00$ in stock
43470 25 mg 410.00$ in stock
53470 50 mg 695.00$ in stock
63470 100 mg 1190.00$ in stock

BDP TR is a borondipyrromethene (BODIPY®) dye for ROX channel. This compound is a hydrazide reactive derivative, that can be used for the labeling of aldehydes and ketones with BDP TR.

BDP TR 是一种用于 ROX 通道的硼二吡咯 (BODIPY®) 染料。 该化合物是一种酰肼反应性衍生物，可用于用 BDP TR 标记醛和酮。

Absorption and emission spectra of BDP TR

BDP TR hydrazide

BDP TR hydrazide相关产品

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

Cyanine7.5 hydrazide

Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.

用酰肼部分功能化的近红外荧光团。 对羰基化合物具有反应性，可用于标记糖类和高碘酸盐氧化后的抗体。

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.

Cy5.5 hydrazide 是一种羰基反应性 NIR 染料，特别适用于标记高碘酸盐氧化糖蛋白，即抗体。

General properties

Appearance: violet powder 紫罗兰粉
Mass spec M+ increment: 419.1
Molecular weight: 474.72
Molecular formula: C21H18N4BClF2O2S
Solubility: good in DMF, DMSO, moderate in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19
BODIPY® is a trademark of Life Technologies in some countries.

BDP R6G hydrazide

BDP R6G hydrazide,BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射光谱类似于 R6G（罗丹明 6G）。 这种酰肼是一种羰基反应性化合物，可用于标记醛、酮和大多数碳水化合物（用高碘酸盐氧化）。

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  • BDP R6G hydrazide

BDP R6G hydrazide

标签：Hydrazides, BDP R6G,Reactive dyes,Dye hydrazides
货号 规格 价格 货期
14470 1 mg 110.00$ in stock
24470 5 mg 210.00$ in stock
44470 25 mg 410.00$ in stock
54470 50 mg 695.00$ in stock
64470 100 mg 1190.00$ in stock

BDP R6G is a borondipyrromethene dye whose absorption and emission spectra resemble those of R6G (rhodamine 6G). This hydrazide is a carbonyl-reactive compound that is useful for the labeling of aldehydes, ketones, and most carbohydrates (oxidized with periodate).

BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射光谱类似于 R6G（罗丹明 6G）。 这种酰肼是一种羰基反应性化合物，可用于标记醛、酮和大多数碳水化合物（用高碘酸盐氧化）。

Absorption and emission spectra of BDP R6G

BDP R6G hydrazide

BDP R6G hydrazide相关产品

BDP R6G tetrazine

BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to rhodamine 6G. It contains tetrazine fragment for iedDA ligation.

BDP R6G 四嗪是一种硼二吡咯亚甲基染料，其吸收和发射波长与罗丹明 6G 相似。 它包含用于 iedDA 连接的四嗪片段。

BDP R6G maleimide

BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.

BDP R6G 是一种调谐到 R6G（罗丹明 6G）通道的硼二吡咯亚甲基染料。 这是一种硫醇反应性马来酰亚胺，用于标记蛋白质半胱氨酸残基和其他硫醇。

BDP R6G NHS ester

BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.

BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射光谱与 R6G 相似。

General properties

Appearance: brown powder 棕色粉末
Mass spec M+ increment: 336.1
Molecular weight: 390.62
Molecular formula: C18H18N4BClF2O
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL hydrazide

BDP FL hydrazide，BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性，量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

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  • BDP FL hydrazide

BDP FL hydrazide

标签：BDP FL, Hydrazides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11470 1 mg 110.00$ in stock
21470 5 mg 210.00$ in stock
41470 25 mg 410.00$ in stock
51470 50 mg 695.00$ in stock
61470 100 mg 1190.00$ in stock
BDPFL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays.

Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).

BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性，量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

酰肼基团易于与羰基化合物（醛和酮）结合。

Absorption and emission spectra of BDP FL

BDP FL hydrazide

BDP FL hydrazide相关产品

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

General properties

Appearance: brown to orange solid 棕色至橙色固体
Molecular weight: 342.58
CAS number: 2183473-45-0
Molecular formula: C14H18BClF2N4O
Solubility: poorly soluble in water (20.2 mM = 6.94 g/L), soluble in polar (DMSO, DMF) organic solvents, methanol, moderately soluble in acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  2. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a

BDP 630/650 hydrazide

BDP 630/650 hydrazide,BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料，可用于标记醛和酮，包括糖。

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  • BDP 630/650 hydrazide

BDP 630/650 hydrazide

标签：Hydrazides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15470 1 mg 110.00$ in stock
25470 5 mg 210.00$ in stock
45470 25 mg 410.00$ in stock
55470 50 mg 695.00$ in stock
65470 100 mg 1190.00$ in stock

BDP 630/650 is a red emitting dye which is based on the borodipyrromethene scaffold. This is a carbonyl reactive dye that is useful for the labeling of aldehydes and ketones, including sugars.

BDP 630/650 fluorophore is particularly useful for fluorescence polarization assays.

BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料，可用于标记醛和酮，包括糖。

BDP 630/650 荧光团特别适用于荧光偏振测定。

Absorption and emission spectra of BDP 630/650

BDP 630/650 hydrazide

BDP 630/650 hydrazide相关产品

BDP 581/591 hydrazide

BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

BDP 581/591 是一种具有明亮发射的多用途染料。 这是一种用于与醛和酮结合的酰肼染料。

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

BDP 558/568 是光谱黄色区域的荧光团。 与其他 BDP 染料一样，这种荧光团具有高荧光量子产率、亮度和光稳定性。

BDP 558/568 hydrazide

BDP 558/568 hydrazide is a carbonyl reactive dye with emission in orange/yellow part of the spectrum.

BDP 558/568 酰肼是一种羰基活性染料，在光谱的橙色/黄色部分发射。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 446.1
Molecular weight: 500.76
Molecular formula: C23H20N4BClF2O2S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 hydrazide

BDP 581/591 hydrazide,BDP 581/591 酰肼是一种羰基活性染料。 BDP 581/591 是一种具有明亮发射和出色光稳定性的硼二吡咯亚甲基荧光团。

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  • BDP 581/591 hydrazide

BDP 581/591 hydrazide

标签：Hydrazides, BDP 581/591
货号 规格 价格 货期
16470 1 mg 110.00$ in stock
26470 5 mg 210.00$ in stock
46470 25 mg 410.00$ in stock
56470 50 mg 695.00$ in stock
66470 100 mg 1190.00$ in stock

BDP 581/591 hydrazide is a carbonyl reactive dye. BDP 581/591 is a borondipyrromethene fluorophore with bright emission, and oustanding photostability.

Aldehyde and ketone groups that can be labeled can be obtained by oxidation of 1,2-diol groups in sugars; they are also present in proteins after oxidative stress, and in many small molecules.

BDP 581/591 酰肼是一种羰基活性染料。 BDP 581/591 是一种具有明亮发射和出色光稳定性的硼二吡咯亚甲基荧光团。

可以标记的醛基和酮基可以通过糖中的1,2-二醇基团氧化得到； 它们还存在于氧化应激后的蛋白质中，以及许多小分子中。

Absorption and emission spectra of BDP 581/591

BDP 581/591 hydrazide

BDP 581/591 hydrazide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

DMSO, labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimised for Click and other cojugation reactions

纯二甲亚砜 (DMSO) 溶剂，其质量针对 Click 和其他共轭反应进行了优化

Sulfo-Cyanine7 bis-NHS ester

Sulfo-Cyanine7 bis-NHS ester is a bifunctional derivative of water soluble near infrared sulfo-Cyanine7. It contains two activated ester functional groups.

Sulfo-Cy7 双-NHS 酯是水溶性近红外磺基-Cy7 的双功能衍生物。 它含有两个活化的酯官能团。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 388.2
Molecular weight: 442.7
Molecular formula: C22H22N4BClF2O
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 hydrazide

BDP 558/568 hydrazide,醛/酮类型的羰基在天然和合成分子中很常见。 醛和酮可以用酰肼有效标记，形成稳定的腙。该化合物是 BDP 558/568 染料的羰基反应性酰肼衍生物，在黄色光谱范围内发射。

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  • BDP 558/568 hydrazide

BDP 558/568 hydrazide

标签：Hydrazides,BDP 558/568
货号 规格 价格 货期
17470 1 mg 110.00$ in stock
27470 5 mg 210.00$ in stock
47470 25 mg 410.00$ in stock
57470 50 mg 695.00$ in stock
67470 100 mg 1190.00$ in stock

Carbonyl groups of aldehyde/ketone type are very often found in natural and synthetic molecules. Aldehydes and ketones can be efficiently labeled with hydrazides with the formation of stable hydrazones.

This compound is a carbonyl reactive hydrazide derivative of BDP 558/568 dye which has its emission in yellow range of the spectrum.

醛/酮类型的羰基在天然和合成分子中很常见。 醛和酮可以用酰肼有效标记，形成稳定的腙。

该化合物是 BDP 558/568 染料的羰基反应性酰肼衍生物，在黄色光谱范围内发射。

Absorption and emission spectra of BDP 558/568

BDP 558/568 hydrazide

BDP 558/568 hydrazide相关产品

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.

用于 NHS 酯标记的干燥高纯度无胺溶剂。

BDP 630/650 hydrazide

A carbonyl reactive borondipyrromethene based dye for the red channel (Cyanine5).

用于红色通道 (Cy5) 的羰基活性硼二吡咯亚甲基染料。

Cyanine3 hydrazide

Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.

Cyanine3 hydrazide 是 Cy3 通道的羰基反应性染料。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 396.65
Molecular formula: C16H16N4BClF2OS
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide,sulfo-Cyanine7.5 是一种近红外荧光团，吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式，这是一种马来酰亚胺，用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

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  • sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide

标签：Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine7.5, Cy7.5
货号 规格 价格 货期
16380 1 mg 110.00$ in stock
26380 5 mg 290.00$ in stock
46380 25 mg 690.00$ in stock
56380 50 mg 1270.00$ in stock
66380 100 mg 1990.00$ in stock

sulfo-Cyanine7.5 is a near infrared fluorophore with absorption and emission ranges around 800 nm. Its spectral properties allow for the efficient leveraging of tissue NIR transparency window. The fluorophore is available as different reactive forms, this one is maleimide for the labeling of SH groups of proteins and peptides. The sulfo- version is highly hydrophilic.

Such labeled biomolecules are useful in biodistribution studies and visualization in intact organisms.

sulfo-Cyanine7.5 是一种近红外荧光团，吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式，这是一种马来酰亚胺，用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

这种标记的生物分子可用于生物分布研究和完整生物体的可视化。

Absorption and emission spectra of sulfo-Cyanine7.5

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

TAMRA maleimide, 6-isomer

TAMRA is a well known xanthene dye of rhodamine series. This is a thiol reactive maleimide for the labeling of SH groups in proteins and peptides. Pure 6-isomer.

TAMRA 是众所周知的罗丹明系列呫吨染料。 这是一种硫醇反应性马来酰亚胺，用于标记蛋白质和肽中的 SH 基团。 纯 6 异构体。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1090.3
Molecular weight: 1205.52
Molecular formula: C51H51N4K3O15S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer,TAMRA（也称为 TMR 或四甲基罗丹明）是一种呫吨染料，几十年来一直被用作荧光标记。

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  • TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer

标签：Maleimides, TAMRA (TMR, tetramethylrhodamine)
货号 规格 价格 货期
18180 1 mg 110.00$ in stock
28180 5 mg 210.00$ in stock
48180 25 mg 410.00$ in stock
58180 50 mg 695.00$ in stock
68180 100 mg 1190.00$ in stock

TAMRA (also known as TMR or tetramethylrhodamine) is a xanthene dye that has been used as a fluorescent label for decades. Xanthene dyes are available as two isomers (called 5- and 6-isomers) that have almost identical fluorescent properties, but need to be separated to avoid doubling and smearing of labeled product peaks or bands during chromatography or electrophoresis. This is a pure 6-isomer of TAMRA maleimide, used for the labeling of proteins and peptides via thiol (SH) groups.

TAMRA（也称为 TMR 或四甲基罗丹明）是一种呫吨染料，几十年来一直被用作荧光标记。 呫吨染料有两种异构体（称为 5 异构体和 6 异构体），它们具有几乎相同的荧光特性，但需要分离以避免在色谱或电泳过程中标记的产物峰或带加倍和拖尾。 这是 TAMRA 马来酰亚胺的纯 6 异构体，用于通过硫醇 (SH) 基团标记蛋白质和肽。

Absorption and emission spectra of 6-TAMRA

TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer相关产品

BDP R6G NHS ester

BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.

BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射光谱与 R6G 相似。

TAMRA NHS ester, 5-isomer

Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.

TAMRA 染料的胺反应活性 N-羟基琥珀酰亚胺酯，用于标记蛋白质、肽和氨基寡核苷酸的胺基。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 551.2
Molecular weight: 552.58
Molecular formula: C31H28N4O6
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
  2. Sagert, L.; Hennig, F.; Thomas, C.; Tampé, R. A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor. eLife, 2020, 9, e55326. doi: 10.7554/eLife.55326
  3. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B.J.; Lucey, M.A.; Sasaki, S.; Brierley, D.I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F.C.; Reissaus, C.A.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 2020, 11, 467. doi: 10.1038/s41467-020-14309-w

TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer,TAMRA（四甲基罗丹明）的马来酰亚胺衍生物，用于标记硫醇基团。 TAMRA 的纯 5-异构体。

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  • TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer

标签：Maleimides, TAMRA (TMR, tetramethylrhodamine)
17180 1 mg 110.00$ in stock
27180 5 mg 210.00$ in stock
47180 25 mg 410.00$ in stock
57180 50 mg 695.00$ in stock
67180 100 mg 1190.00$ in stock

Maleimide derivative of TAMRA (tetramethylrhodamine) for the labeling of thiol groups. Pure 5-isomer of TAMRA.

TAMRA（四甲基罗丹明）的马来酰亚胺衍生物，用于标记硫醇基团。 TAMRA 的纯 5-异构体。

Absorption and emission spectra of 5-TAMRA

TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer相关产品

FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

AF430 NHS ester

AF430 is a hydrophilic coumarin dye with the emission in green-yellow range. The NHS ester is used for the labeling of amine groups.

AF430 是一种亲水性香豆素染料，发射在黄绿色范围内。 NHS 酯用于标记胺基。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: red powder  红色粉末
Mass spec M+ increment: 552.2
Molecular weight: 552.58
Molecular formula: C31H28N4O6
IUPAC name: 1-[2-({3′,6′-Bis(dimethylamino)-3-oxospiro[isobenzofuran-1,9′-xanthen]-5-yl}carbonylamino)ethyl]-1H-pyrrole-2,5-dione
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide,一种带有马来酰亚胺基团的活性染料，用于标记蛋白质和其他生物分子的硫醇基团，是 Cy7® 马来酰亚胺的类似物。

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  • Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide

标签：sulfo-Cyanine7, Cy7,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15380 1 mg 110.00$ in stock
25380 5 mg 290.00$ in stock
45380 25 mg 690.00$ in stock
55380 50 mg 1270.00$ in stock
65380 100 mg 1990.00$ in stock

A reactive dye with a maleimide group for the labeling of thiol groups of proteins and other biomolecules, an analog of Cy7® maleimide.

Sulfo-Cyanine7 is a near infrared fluorophore which is hydrophilic and contains a rigidizing ring in its heptamethine chain that improves its photophysical properties. A great dye for various applications, including NIR imaging.

一种带有马来酰亚胺基团的活性染料，用于标记蛋白质和其他生物分子的硫醇基团，是 Cy7® 马来酰亚胺的类似物。

Sulfo-Cyanine7 是一种近红外荧光团，具有亲水性，在其七甲碱链中包含一个刚性环，可改善其光物理性质。 适用于各种应用的出色染料，包括 NIR 成像。

Sulfo-Cyanine7 maleimide absorbance and emission spectra

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Cyanine7.5 maleimide

Cyanine7.5 maleimide is a thiol reactive near infrared dye.

Cy7.5 马来酰亚胺是一种硫醇活性近红外染料。

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的花青5 胺官能化染料。

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 868.2
Molecular weight: 869.10
CAS number: 2183440-60-8 (potassium salt), 2183440-59-5 (inner salt)
Molecular formula: C43H49KN4O9S2
IUPAC name: 1-[2-(6-{2-[(E)-2-[(E)-3-{(E)-2-[1-Methyl-3,3-dimethyl-5-(oxysulfonyl)-2-indolinylidene]ethylidene}-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-(oxysulfonyl)-3H-indol-1-yl}hexanoylamino)ethyl]-1H-pyrrole-2,5-dione, potassium salt
Solubility: Good in water, DMF, DMSO. Low in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献：

  1. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, in press. doi: 10.1021/acs.chemmater.1c02844
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide,Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

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  • Reactive dyes
  • Dye maleimides
  • Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide

标签：Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17380 1 mg 110.00$ in stock
27380 5 mg 290.00$ in stock
47380 25 mg 690.00$ in stock
57380 50 mg 1270.00$ in stock
67380 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案，应使用适当的还原剂（例如 TCEP）还原天然蛋白质的二硫键。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

BDP TMR maleimide

A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.

用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定，以及其他应用。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5&reg; channel.

用于 Cy5&reg; 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  2. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide,水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

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  • Reactive dyes
  • Dye maleimides
  • Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide

标签：sulfo-Cyanine5, Cy5,Maleimides, Microscopy
货号 规格 价格 货期
13380 1 mg 110.00$ in stock
23380 5 mg 290.00$ in stock
43380 25 mg 690.00$ in stock
53380 50 mg 1270.00$ in stock
63380 100 mg 1990.00$ in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

也可使用不含磺基的类似物 Cyanine5 马来酰亚胺。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide相关产品

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

ROX NHS ester, 6- isomer

Pure isomer 6-ROX NHS ester for amine labeling.

用于胺标记的纯异构体 6-ROX NHS 酯。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark blue powder  深蓝色粉末
Molecular weight: 803.00
CAS number: 2242791-82-6
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide,Sulfo-Cy3 马来酰亚胺是一种水溶性硫醇活性染料，可用于标记亲水性磺基-Cyanine3 荧光团。 这是 Cy3® 马来酰亚胺的类似物。

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  • Dye maleimides
  • Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

标签：Maleimides, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
11380 1 mg 110.00$ in stock
21380 5 mg 290.00$ in stock
41380 25 mg 690.00$ 5 days
51380 50 mg 1270.00$ in stock
61380 100 mg 1990.00$ in stock

Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3® maleimide.

This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.

A non-sulfonated Cyanine3 maleimide is available.

Sulfo-Cyanine3 马来酰亚胺是一种水溶性硫醇活性染料，可用于标记亲水性磺基-Cyanine3 荧光团。 这是 Cy3® 马来酰亚胺的类似物。

该产品推荐用于在温和的纯水性条件下标记抗体和其他不稳定的蛋白质。 该染料是水溶性的，不需要使用有机助溶剂。

可使用非磺化的 Cyanine3 马来酰亚胺。

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide相关产品

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cyanine3 SE 活化酯。

General properties

Appearance: red powder 红色粉末
Molecular weight: 776.96
CAS number: 1656990-68-9
Molecular formula: C36H41KN4O9S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: soluble in water (0.39 M = 30 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, 2021, 49(5), 2450–2459. doi: 10.1093/nar/gkab040
Cy® is a trademark of GE Healthcare.

ROX maleimide, 5-isomer

ROX maleimide, 5-isomer,ROX 是一种明亮的罗丹明染料，最大发射波长约为 580 nm。 它广泛用于标记生物分子。 与其他罗丹明染料一样，它有两种异构体，5-ROX 和 6-ROX。 尽管这些异构体具有几乎相同的光谱特性，但需要将它们分离以避免在 HPLC 或电泳中标记产物加倍。

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  • ROX maleimide, 5-isomer

ROX maleimide, 5-isomer

标签：ROX (Rhodamine X, Rhodamine 101), Maleimides
货号 规格 价格 货期
11280 1 mg 110.00$ in stock
21280 5 mg 210.00$ in stock
41280 25 mg 410.00$ in stock
51280 50 mg 695.00$ in stock
61280 100 mg 1190.00$ in stock

ROX is a bright rhodamine dye with emission maximum around 580 nm. It is widely used for the labeling of biomolecules. As other rhodamine dyes, it comes as two isomers, 5-ROX and 6-ROX. Although these isomers have almost identical spectral properties, they need to be separated to avoid doubling of labeled products on HPLC or electrophoresis.

This derivative contains thiol-reactive maleimide moiety for the attachment of ROX fluorophore to SH groups, such as cystein residues in proteins and peptides.

ROX 是一种明亮的罗丹明染料，最大发射波长约为 580 nm。 它广泛用于标记生物分子。 与其他罗丹明染料一样，它有两种异构体，5-ROX 和 6-ROX。 尽管这些异构体具有几乎相同的光谱特性，但需要将它们分离以避免在 HPLC 或电泳中标记产物加倍。

该衍生物含有硫醇反应性马来酰亚胺部分，用于将 ROX 荧光团连接到 SH 基团，例如蛋白质和肽中的半胱氨酸残基。

Absorption and emission spectra of ROX

ROX maleimide, 5-isomer

ROX maleimide, 5-isomer相关文献

BDP R6G maleimide

BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.

BDP R6G 是一种调谐到 R6G（罗丹明 6G）通道的硼二吡咯亚甲基染料。 这是一种硫醇反应性马来酰亚胺，用于标记蛋白质半胱氨酸残基和其他硫醇。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

General properties

Appearance: red powder  红色粉末
Mass spec M+ increment: 656.3
Molecular weight: 656.73
Molecular formula: C39H36N4O6
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.00

Pyrene maleimide

Pyrene maleimide,Pyrene 是一种在蓝色区域发射的荧光碳氢化合物。 这是与硫醇反应的芘丁酸的马来酰亚胺衍生物。

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  • Pyrene maleimide

Pyrene maleimide

标签：Maleimides, Pyrene
货号 规格 价格 货期
13580 1 mg 110.00$ in stock
23580 5 mg 210.00$ in stock
43580 25 mg 410.00$ in stock
53580 50 mg 695.00$ in stock
63580 100 mg 1190.00$ in stock

Pyrene is a fluorescent hydrocarbon which emits in blue region. This is a maleimide derivative of pyrenebutyric acid which reacts with thiols.

Pyrene is a useful proximity probe because two pyrene residues close to each other exhibit strong excimer fluorescence.

Pyrene 是一种在蓝色区域发射的荧光碳氢化合物。 这是与硫醇反应的芘丁酸的马来酰亚胺衍生物。

Pyrene 是一种有用的邻近探针，因为彼此靠近的两个芘残基表现出强烈的准分子荧光。

Absorption and emission spectra of pyrene fluorophore

Pyrene maleimide

Pyrene maleimide相关产品

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

氨基反应性 BDP FL，一种非常明亮且光稳定的荧光素通道染料。

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling

用于蛋白质标记的 Cy2 NHS 酯最小染料

BDP FL maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy.

BDP FL 马来酰亚胺是一种用于蛋白质标记的明亮且光稳定的硫醇反应性染料，是显微镜下荧光素的理想替代品。

General properties

Appearance: off white solid 灰白色固体
Mass spec M+ increment: 410.2
Molecular weight: 410.46
CAS number: 1869968-64-8
Molecular formula: C26H22N2O3
Solubility: well soluble in chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer,FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

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  • FAM maleimide, 6-isomer

FAM maleimide, 6-isomer

标签：FAM (Fluorescein), Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
24180 5 mg – in stock
44180 25 mg 160.00$ in stock
54180 50 mg 270.00$ in stock
64180 100 mg 420.00$ in stock

FAM (fluorescein) is a bright fluorophore which is compatible with various fluorescence detection instruments. FAM is a universal dye that is useful for microscopy, qPCR and many other methods as well as for FRET-based and fluorescence polarization based binding assays.

FAM maleimide is a thiol reactive dye for the labeling of proteins, peptides, and other thiolated molecules.

FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

FAM 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质、肽和其他硫醇化分子。

Fluorescein (FAM) absorbance and emission spectra

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer相关产品

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物，用于 FAM（荧光素）488 nm 通道的硼二吡咯亚甲基染料。

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR（近红外）染料叠氮化物，适用于铜催化和无铜点击化学。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 498.4
Molecular weight: 498.44
Molecular formula: C27H18N2O8
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  2. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  3. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  4. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680

Cyanine7.5 maleimide

Cyanine7.5 maleimide,硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团，Cy7.5® 马来酰亚胺的类似物。

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  • Cyanine7.5 maleimide

Cyanine7.5 maleimide

标签：Cyanine7.5, Cy7.5,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
16080 1 mg 110.00$ in stock
26080 5 mg 210.00$ in stock
46080 25 mg 410.00$ 5 days
56080 50 mg 695.00$ in stock
66080 100 mg 1190.00$ in stock

Thiol-reactive, near infrared dye Cyanine7.5 for the labeling of protein SH groups, an analog of Cy7.5® maleimide.

Most proteins contain sulfhydryl groups which can be selectively labeled with maleimides. With this reagent, these proteins can be converted to near infrared (NIR) fluorescent conjugates. After it, the conjugates can be used in non-invasive live organism imaging to study distribution of the protein in tissues and organs.

硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团，Cy7.5® 马来酰亚胺的类似物。

大多数蛋白质含有巯基，可以选择性地用马来酰亚胺标记。 使用该试剂，这些蛋白质可以转化为近红外 (NIR) 荧光结合物。 之后，缀合物可用于非侵入性活体生物成像，以研究蛋白质在组织和器官中的分布。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 maleimide

Cyanine7.5 maleimide相关产品

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cyanine7 NHS 酯是一种水溶性、近红外、胺反应性染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: green powder  绿色粉末
Molecular weight: 807.46
Molecular formula: C51H55ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献：

  1. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
Cy® is a trademark of GE Healthcare.

Cyanine7 maleimide

Cyanine7 maleimide,近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

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  • Cyanine7 maleimide

Cyanine7 maleimide

标签：Cyanine7,Cy7, Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15080 1 mg 110.00$ in stock
25080 5 mg 210.00$ in stock
45080 25 mg 410.00$ in stock
55080 50 mg 695.00$ in stock
65080 100 mg 1190.00$ in stock

Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。

该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

Cyanine7 absorbance and emission spectra

Cyanine7 maleimide

Cyanine7 maleimide相关产品

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

用于 TCO 连接的含有四嗪基团的近红外 Cy7 染料衍生物。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 707.34
CAS number: 2120392-49-4 (without anion)
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  2. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  3. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  4. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
Cy® is a trademark of GE Healthcare.

Cyanine5.5 maleimide

Cyanine5.5 maleimide,Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

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  • Cyanine5.5 maleimide

Cyanine5.5 maleimide

标签：Cyanine5.5, Cy5.5,Maleimides, Microscopy
货号 规格 价格 货期
17080 1 mg 110.00$ 5 days
27080 5 mg 210.00$ in stock
47080 25 mg 410.00$ in stock
57080 50 mg 695.00$ in stock
67080 100 mg 1190.00$ in stock

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

Cyanine5.5 的近红外发射使这种染料适用于生物成像应用。

Cyanine5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 maleimide

Cyanine5.5 maleimide相关产品

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cyanine5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

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Cyanine7.5 azide

Long-wavelength NIR fluorescent dye azide for Click chemistry.

用于点击化学的长波长 NIR 荧光染料叠氮化物。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 741.36
CAS number: 1593644-50-8
Molecular formula: C46H49ClN4O3
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508
  2. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  3. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  4. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383

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Cy® is a trademark of Cytiva.

Cyanine5 maleimide

Cyanine5 maleimide,Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

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  • Reactive dyes
  • Dye maleimides
  • Cyanine5 maleimide

Cyanine5 maleimide

标签：Cyanine5,Cy5, Maleimides, Microscopy
货号 规格 价格 货期
13080 1 mg 110.00$ in stock
23080 5 mg 210.00$ in stock
43080 25 mg 410.00$ in stock
53080 50 mg 695.00$ in stock
63080 100 mg 1190.00$ in stock

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates.

Cyanine5 is an analog of Cy5®, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers.

For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.

Cy5 马来酰亚胺是一种单反应性染料，可选择性地与硫醇基团（例如，与肽和蛋白质中的半胱氨酸）偶联，形成标记的偶联物。

Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

对于抗体和敏感蛋白的标记，我们建议使用水溶性磺基-Cyanine5 马来酰亚胺。

Cy5 excitation and emission spectra

Cyanine5 maleimide

Cyanine5 maleimide相关产品

FAM hydrazide, 5-isomer

FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.

FAM 酰肼是一种羰基反应性荧光素衍生物。 纯5-异构体。 可以用羰基标记氧化的蛋白质、糖类和许多小分子。

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Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 605.8
CAS number: 1437872-46-2 (without anion)
Molecular formula: C38H45N4O3
IUPAC name: 3H-​Indolium, 2-​[5-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​3,​3-​trimethyl-
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Pishesha, N.; Harmand, T.; Smeding, L.; Ma, W.; Ludwig, L.; Janssen, R.; Islam, A.; Xie, Y.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H.; Ploegh, H. Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance. Research Square, preprint. doi: 10.21203/rs.3.rs-192181/v1
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  4. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
Cy® is a trademark of GE Healthcare.

Cyanine3 maleimide

Cyanine3 maleimide,硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cy3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

  • Products
  • Reactive dyes
  • Dye maleimides
  • Cyanine3 maleimide

Cyanine3 maleimide

标签：Cyanine3, Cy3,Maleimides, Microscopy
货号 规格 价格 货期
11080 1 mg 110.00$ in stock
21080 5 mg 210.00$ in stock
41080 25 mg 410.00$ in stock
51080 50 mg 695.00$ in stock
61080 100 mg 1190.00$ in stock

Thiol mono-reactive Cyanine3 dye. This reagent can be used to attach Cyanine3 fluorophore (an analog of Cy3®) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides).

Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or other appropriate reductant prior to the labeling.

Labeling with Cyanine3 maleimide is selective, and efficient.

We recommend using water-soluble Sulfo-Cyanine3 maleimide for the labeling of antibodies and other sensitive proteins.

硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cyanine3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

标记前应使用 TCEP（三羧乙基膦）或其他合适的还原剂还原胱氨酸。

用 Cyanine3 马来酰亚胺标记具有选择性且有效。

我们建议使用水溶性 Sulfo-Cyanine3 马来酰亚胺标记抗体和其他敏感蛋白。

Cy3 absorbance and emission spectra

Cyanine3 maleimide

Cyanine3 maleimide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

Sulfo-Cyanine3 carboxylic acid

Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.

Sulfo-Cyanine3 不含未活化的单官能羧酸，水溶性染料。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

General properties

Appearance: red powder  红色粉末
Molecular weight: 666.56
Molecular formula: C36H43N4O3BF4
Solubility: well soluble in DMSO (0.50 M = 330 g/L), in DMF, dichloromethane, very poorly soluble in water (0.57 mM = 420 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  2. Budiardjo, S.J.; Deay, J.J.; Calkins, A.L.; Wimalasena, V.K.; Montezano, D.; Biteen, J.S.; Slusky, J.S.G. Colicin E1 Fragments Potentiate Antibiotics by Plugging TolC. bioRxiv, preprint. doi: 10.1101/692251
  3. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  4. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
Cy® is a trademark of GE Healthcare.

BDP TR maleimide

BDP TR maleimide,BDP TR 是一种吸收和发射类似于 ROX 的硼二吡咯亚甲基染料。 与ROX相比，其荧光量子产率和亮度要高得多。

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  • BDP TR maleimide

BDP TR maleimide

标签：Maleimides, BDP TR
货号 规格 价格 货期
13480 1 mg 110.00$ in stock
23480 5 mg 210.00$ in stock
43480 25 mg 410.00$ in stock
53480 50 mg 695.00$ in stock
63480 100 mg 1190.00$ in stock
BDP TR is a borondipyrromethene dye with absorption and emission similar to ROX. Compared to ROX, its fluorescence quantum yield and brightness is much higher.

Maleimide can be conjugated with thiol groups of proteins and peptides.

BDP TR 是一种吸收和发射类似于 ROX 的硼二吡咯亚甲基染料。 与ROX相比，其荧光量子产率和亮度要高得多。

马来酰亚胺可以与蛋白质和肽的硫醇基团结合。

Absorption and emission spectra of BDP TR

BDP TR maleimide

BDP TR maleimide相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

Coumarin 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是Coumarin 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 545.1
Molecular weight: 546.35
Molecular formula: C27H21N4BF2O4S
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19

BDP TMR maleimide

BDP TMR maleimide,BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

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  • BDP TMR maleimide

BDP TMR maleimide

标签：Maleimides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12480 1 mg 110.00$ in stock
22480 5 mg 210.00$ in stock
42480 25 mg 410.00$ in stock
52480 50 mg 695.00$ in stock
62480 100 mg 1190.00$ in stock

BDP TMR is a bright borondipyrromethene fluorophore for the TAMRA channel. This maleimide derivative is suitable for conjuction with thiol groups as e.g. in protein side chains.

BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

Absorption and emission spectra of BDP TMR

BDP TMR maleimide

BDP TMR maleimide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

BDP TR NHS ester

BDP TR is a borondipyrromethene dye. A bright and photostable fluorophore with high quantum yield.

BDP TR 是一种硼二吡咯亚甲基染料。 具有高量子产率的明亮且光稳定的荧光团。

General properties

Appearance: purple powder  紫色粉末
Mass spec M+ increment: 520.2
Molecular weight: 520.34
CAS number: 2183473-34-7
Molecular formula: C27H27BF2N4O4
IUPAC name: 2-(2-(N-maleimidoethylaminocarbonylethyl))-1,3-dimethyl-5-(4-methoxyphenyl)-4,4-difluoroborondipyrromethene
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献：

  1. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084

BDP R6G maleimide

BDP R6G maleimide,BDP R6G 是一种硼二吡咯亚甲基荧光团，其吸收和发射光谱与罗丹明 6G (R6G) 染料相匹配。

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  • BDP R6G maleimide

BDP R6G maleimide

标签：Maleimides, BDP R6G
货号 规格 价格 货期
14480 1 mg 110.00$ in stock
24480 5 mg 210.00$ in stock
44480 25 mg 410.00$ in stock
54480 50 mg 695.00$ in stock
64480 100 mg 1190.00$ in stock

BDP R6G is a borondipyrromethene fluorophore whose absorption and emission spectra match those of rhodamine 6G (R6G) dye.

Thiol labeling is often an option of choice for the modification of proteins. Limited number of cysteine residues in proteins allow for more site-specific labeling than NHS ester labeling of amine groups, which are encountered in large number in many proteins.

This maleimide is a thiol reactive dye. Please refer to our recommended labeling protocol to achieve modification of your protein with this reagent.

BDP R6G 是一种硼二吡咯亚甲基荧光团，其吸收和发射光谱与罗丹明 6G (R6G) 染料相匹配。

硫醇标记通常是蛋白质修饰的一种选择。 蛋白质中有限数量的半胱氨酸残基允许比 NHS 酯标记胺基团更多的位点特异性标记，这在许多蛋白质中大量遇到。

这种马来酰亚胺是一种硫醇活性染料。 请参考我们推荐的标记方案，以使用该试剂对您的蛋白质进行修饰。

Absorption and emission spectra of BDP R6G

BDP R6G maleimide

BDP R6G maleimide相关产品

BDP 650/665 maleimide

This maleimide is a thiol reactive derivative of BDP 650/665, a borondipyrromethene dye for Cyanine5 (Cy5) channel.

该马来酰亚胺是 BDP 650/665 的硫醇活性衍生物，BDP 650/665 是一种用于花青 5 (Cy5) 通道的硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: red or brown solid  红色或棕色固体
Mass spec M+ increment: 462.2
Molecular weight: 462.26
CAS number: 2183473-32-5
Molecular formula: C24H21N4BF2O3
IUPAC name: 1-Phenyl-6-(2-(2-(N-maleimido)ethylaminocarbonyl)ethyl)borondipyrromethene
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL maleimide

BDP FL maleimide,硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

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  • BDP FL maleimide

BDP FL maleimide

标签：BDP FL, Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11480 1 mg 110.00$ in stock
21480 5 mg 210.00$ in stock
41480 25 mg 410.00$ in stock
51480 50 mg 695.00$ in stock
61480 100 mg 1190.00$ in stock

Thiol reactive BDP FL maleimide is a reactive dye for protein labeling, which has identical structure with BODIPY® FL maleimide.

BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. Its brightness is similar to fluorescein, R110 and xanthene dye derivatives.

This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.

硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

BDP FL 是一种硼二吡咯亚甲基染料，其吸收光谱和荧光光谱与荧光素 (FAM) 相似。 然而，这种染料表现出非常高的光稳定性。 它是不带电的，并且具有低分子量。 其亮度类似于荧光素、R110 和呫吨染料衍生物。

这种荧光团是荧光显微镜和许多其他应用的理想选择。 荧光团几乎可以在任何应用中替代荧光素，并且与任何支持 FAM 的荧光仪器兼容。

Absorption and emission spectra of BDP FL

BDP FL maleimide

BDP FL maleimide相关产品

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

EDC, coupling grade

Water soluble carbodiimide for the coupling of carboxylic acids with amines.

用于羧酸与胺偶联的水溶性碳二亚胺。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

General properties

Appearance: orange solid  橙色固体
Mass spec M+ increment: 414.1
Molecular weight: 414.21
CAS number: 773859-49-7
Molecular formula: C20H21BF2N4O3
Solubility: Good in organic solvents (DMF, DMSO), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  2. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  3. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  4. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
BODIPY® is a trademark of Life Technologies.

BDP 650/665 maleimide

BDP 650/665 maleimide,BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性，但可用于标记水环境中的生物分子，因此是 Cy5 的良好替代品。

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  • BDP 650/665 maleimide

BDP 650/665 maleimide

标签：Maleimides, Near infrared (NIR) imaging, BDP 650/665
货号 规格 价格 货期
18480 1 mg 110.00$ in stock
28480 5 mg 210.00$ in stock
48480 25 mg 410.00$ in stock
58480 50 mg 695.00$ in stock
68480 100 mg 1190.00$ in stock

Maleimide is a thiol reactive group. The compound can be used for the labeling of cysteine residues of proteins and peptides, among other SH-containing molecules.

BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性，但可用于标记水环境中的生物分子，因此是 Cy5 的良好替代品。

马来酰亚胺是硫醇反应基团。 该化合物可用于标记蛋白质和肽以及其他含 SH 分子的半胱氨酸残基。

Absorption and emission spectra of BDP 650/665

BDP 650/665 maleimide

BDP 650/665 maleimide相关产品

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

BDP TR maleimide

BDP TR is a multi-purpose fluorophore with absorption and emission channels matching ROX dye. BDP TR is suitable for two photon, and fluorescence polarization studies.

BDP TR 是一种多用途荧光团，具有与 ROX 染料匹配的吸收和发射通道。 BDP TR 适用于两个光子和荧光偏振研究。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 555.2
Molecular weight: 555.34
Molecular formula: C29H24N5BF2O4
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

BDP 630/650 maleimide

BDP 630/650 maleimide,BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长，这种染料对于荧光寿命相关的测量特别有用。

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  • BDP 630/650 maleimide

BDP 630/650 maleimide

标签：Maleimides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15480 1 mg 110.00$ in stock
25480 5 mg 210.00$ in stock
45480 25 mg 410.00$ in stock
55480 50 mg 695.00$ in stock
65480 100 mg 1190.00$ in stock

BDP 630/650 is a far red emitting borondipyrromethene based fluorophore for the Cyanine5 channel. Because of its relatively long lifetime of the excited state, this dye is particularly useful for fluorescence lifetime related measurements.

The reactive maleimide moiety allows to attach the dye to thiol groups in biomolecules, especially proteins and peptides.

BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长，这种染料对于荧光寿命相关的测量特别有用。

反应性马来酰亚胺部分允许将染料连接到生物分子中的硫醇基团，尤其是蛋白质和肽。

Absorption and emission spectra of BDP 630/650

BDP 630/650 maleimide

BDP 630/650 maleimide相关产品

BDP 650/665 X NHS ester

Amine reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel, possessing a high molar extinction coefficient, and a good emission quantum yield.

BDP 650/665 的胺反应物，一种用于 Cy5 通道的硼二吡咯亚甲基染料，具有高摩尔消光系数和良好的发射量子产率。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cy5.5 染料衍生物。

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

用于肽和蛋白质的叠氮基标记的活化酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 572.2
Molecular weight: 572.39
CAS number: 2183473-31-4
Molecular formula: C29H23N4BF2O4S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 maleimide

BDP 581/591 maleimide,BDP 581/591 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质和肽的巯基。

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BDP 581/591 maleimide

标签：Maleimides, Fluorescence polarization, BDP 581/591
货号 规格 价格 货期
16480 1 mg 110.00$ in stock
26480 5 mg 210.00$ in stock
46480 25 mg 410.00$ in stock
56480 50 mg 695.00$ in stock
66480 100 mg 1190.00$ in stock
BDP 581/591 maleimide is a thiol reactive dye for the labeling of sulfhydryl groups of proteins and peptides.

The dye is useful for a variety of applications, such as microscopy, fluorescence polarization experiments, and even ROS detection (upon reaction with ROS, the dye changes its fluorescence).

BDP 581/591 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质和肽的巯基。

该染料可用于多种应用，例如显微镜检查、荧光偏振实验，甚至 ROS 检测（与 ROS 反应后，染料会改变其荧光）。

Absorption and emission spectra of BDP 581/591

BDP 581/591 maleimide

BDP 581/591 maleimide相关产品

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物，用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验，并可用作 ROS 探针。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 514.33
Molecular formula: C28H25N4BF2O3
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 maleimide

BDP 558/568 maleimide,BDP 558/568 是一种荧光团，最大荧光波长为 569 nm（在黄色光谱范围内）。 该染料具有低斯托克斯位移、高量子产率； 它是疏水的，对 pH 变化或溶剂极性相对不敏感。 根据其光谱特性，BDP 558/568 类似于 BODIPY™ 558/568 和 Cy3™ 等荧光团。 BDP 558/568 马来酰亚胺可用于与肽、蛋白质、抗体或其他含有游离硫醇基 (-SH) 的分子结合。

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  • BDP 558/568 maleimide

BDP 558/568 maleimide

标签：Maleimides, BDP 558/568
货号 规格 价格 货期
A7480 1 mg 110.00$ in stock
B7480 5 mg 210.00$ in stock
C7480 10 mg 310.00$ in stock
D7480 25 mg 410.00$ in stock
E7480 50 mg 695.00$ in stock
F7480 100 mg 1190.00$ in stock

BDP 558/568 is a fluorophore with a fluorescence maximum at 569 nm (in the yellow spectrum range). This dye has a low Stokes shift, high quantum yield; it is hydrophobic and relatively non-sensitive to pH changes or solvent polarity. By its spectral characteristics, BDP 558/568 is an analog of such fluorophores as BODIPY™ 558/568 and Cy3™. BDP 558/568 maleimide can be used for conjugation with peptides, proteins, antibodies, or other molecules that contain free thiol groups (-SH).

BDP 558/568 是一种荧光团，最大荧光波长为 569 nm（在黄色光谱范围内）。 该染料具有低斯托克斯位移、高量子产率； 它是疏水的，对 pH 变化或溶剂极性相对不敏感。 根据其光谱特性，BDP 558/568 类似于 BODIPY™ 558/568 和 Cy3™ 等荧光团。 BDP 558/568 马来酰亚胺可用于与肽、蛋白质、抗体或其他含有游离硫醇基 (-SH) 的分子结合。

Absorption and emission spectra of BDP 558/568

BDP 558/568 maleimide

BDP 558/568 maleimide相关产品

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

BDP 558/568 是光谱黄色区域的荧光团。 与其他 BDP 染料一样，这种荧光团具有高荧光量子产率、亮度和光稳定性。

BDP 558/568 amine

BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. This amine derivative can be conjugated by means of reactions with various electrophiles.

BDP 558/568 是一种具有黄色/橙色发射光的硼二吡咯亚甲基染料。 这种胺衍生物可以通过与各种亲电子试剂的反应来缀合。

BDP 558/568 carboxylic acid

BDP 558/568 is a borondipyrromethene dye with yellow emission. The dye as a carboxylic acid can be used in peptide synthesis (after appropriate activation of the carboxylic group).

BDP 558/568 是一种具有黄色发射光的硼二吡咯亚甲基染料。 作为羧酸的染料可用于肽合成（在适当活化羧基后）。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 468.28
Molecular formula: C22H19N4BF2O3S
IUPAC name: 3-(5,5-difluoro-7-(thiophen-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-3-yl)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)propanamide
Solubility: very soluble in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07
BODIPY™ is a trademark of Thermo Fisher Scientific. Cy™ is a trademark of Cytiva.

AF430 maleimide

AF430 maleimide,AF430 是香豆素性质的亲水染料。 该染料用于流式细胞术。这种马来酰亚胺衍生物对硫醇基团具有反应性。 因此，它可以标记许多蛋白质，包括那些驻留在细胞表面的蛋白质。

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  • AF430 maleimide

AF430 maleimide

标签：Maleimides, AF430
货号 规格 价格 货期
10880 1 mg 110.00$ in stock
20880 5 mg 290.00$ in stock
40880 25 mg 690.00$ in stock
50880 50 mg 1270.00$ in stock
60880 100 mg 1990.00$ in stock

AF430 is a hydrophilic dye of coumarin nature. The dye is used in flow cytometry.

This maleimide derivative is reactive against thiol groups. Therefore, it allows to label many proteins, including those residing on cell surface.

AF430 是香豆素性质的亲水染料。 该染料用于流式细胞术。

这种马来酰亚胺衍生物对硫醇基团具有反应性。 因此，它可以标记许多蛋白质，包括那些驻留在细胞表面的蛋白质。

Absorption and emission spectra of AF430

AF430 maleimide

AF430 maleimide相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

TAMRA NHS ester, 5-isomer

Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.

TAMRA 染料的胺反应活性 N-羟基琥珀酰亚胺酯，用于标记蛋白质、肽和氨基寡核苷酸的胺基。

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cyanine3 染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 625.2
Molecular weight: 726.8
Molecular formula: C34H45N4F3O8S
IUPAC name: (8-{6-[2-(2,5-Dioxo-1H-pyrrol-1-yl)ethylamino]-6-oxohexyl}-7,7-dimethyl-2-oxo-4-(trifluoromethyl)-1-oxa-8-aza-5,6,7,8-tetrahydroanthr-5-yl)methanesulfonic acid
Solubility: soluble in water, polar organic solvents (DMF, DMSO)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 430
ε, L⋅mol−1⋅cm−1: 15955
Emission maximum, nm: 542
Fluorescence quantum yield: 0.23
CF260: 0.06
CF280: 0.06

TAMRA alkyne, 6-isomer

TAMRA alkyne, 6-isomer,四甲基罗丹明 (TAMRA) 炔烃，纯 6 异构体。 TAMRA 是一种流行的染料，用于 qPCR 和其他应用。 它与 FAM 形成 FRET 对（作为受体）。

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  • TAMRA alkyne, 6-isomer

TAMRA alkyne, 6-isomer

标签：Alkynes, TAMRA (TMR, tetramethylrhodamine)
货号 规格 价格 货期
A81B0 1 mg – in stock
B81B0 5 mg 135.00$ in stock
C81B0 10 mg 240.00$ in stock
D81B0 25 mg 380.00$ in stock
E81B0 50 mg 695.00$ in stock

Tetramethylrhodamine (TAMRA) alkyne, pure 6-isomer. TAMRA is a popular dye that is used in qPCR and other applications. It forms a FRET pair with FAM (serving as an acceptor).

This product is a terminal alkyne for copper-catalyzed Click chemistry. It can be conjugated with azide groups using CuAAc reaction.

四甲基罗丹明 (TAMRA) 炔烃，纯 6 异构体。 TAMRA 是一种流行的染料，用于 qPCR 和其他应用。 它与 FAM 形成 FRET 对（作为受体）。

该产品是用于铜催化点击化学的末端炔烃。 它可以通过 CuAAc 反应与叠氮基团结合。

Absorption and emission spectra of 6-TAMRA

TAMRA alkyne, 6-isomer

TAMRA alkyne, 6-isomer相关产品

Cyanine3 NHS ester minimal dye

Cyanine3 minimal dye for protein labeling.

用于蛋白质标记的 Cy3 最小染料。

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cyanine5 活化酯，用于标记蛋白质、肽和其他分子。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 467.2
Molecular weight: 467.52
Molecular formula: C28H25N3O4
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.34
CF280: 0.17

相关文献：

  1. Rink, W.M.; Thomas, F. Decoration of Coiled-Coil Peptides with N-Cysteine Peptide Thioesters As Cyclic Peptide Precursors Using Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) Click Reaction. Organic Letters, 2018, 20(23), 7493–7497. doi: 10.1021/acs.orglett.8b03261

TAMRA alkyne, 5-isomer

TAMRA alkyne, 5-isomer,用于点击化学的 TAMRA 炔烃，纯 5 异构体。 TAMRA（TMR，四甲基罗丹明）是一种呫吨染料。 它与荧光素形成 FRET 对。

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  • TAMRA alkyne, 5-isomer

TAMRA alkyne, 5-isomer

标签：Alkynes, TAMRA (TMR, tetramethylrhodamine)
货号 规格 价格 货期
A71B0 1 mg – in stock
B71B0 5 mg 135.00$ in stock
C71B0 10 mg 240.00$ in stock
D71B0 25 mg 380.00$ in stock
E71B0 50 mg 695.00$ in stock
F71B0 100 mg 1190.00$ in stock

TAMRA alkyne for Click chemistry, pure 5-isomer. TAMRA (TMR, tetramethylrhodamine) is a xanthene dye. It forms a FRET pair with fluorescein.

This alkyne is suitable for Copper-catalyzed Click chemistry (CuAAC).

用于点击化学的 TAMRA 炔烃，纯 5 异构体。 TAMRA（TMR，四甲基罗丹明）是一种呫吨染料。 它与荧光素形成 FRET 对。

该炔烃适用于铜催化点击化学 (CuAAC)。

Absorption and emission spectra of 5-TAMRA

TAMRA alkyne, 5-isomer

TAMRA alkyne, 5-isomer

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cyanine5 炔烃是一种用于 Click Chemistry 的炔烃染料。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) 是一种用于无铜点击化学的环炔烃染料衍生物。

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cyanine3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

General properties

Appearance: violet solid  紫罗兰色固体
Mass spec M+ increment: 467.2
Molecular weight: 467.51
CAS number: 945928-17-6
Molecular formula: C28H25N3O4
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Rojas-Sánchez, L.; Sokolova, V.; Riebe, S.; Voskuhl, J.; Epple, M. Covalent Surface Functionalization of Calcium Phosphate Nanoparticles with Fluorescent Dyes by Copper-Catalysed and by Strain-Promoted Azide-Alkyne Click Chemistry. ChemNanoMat, 2019, 5(4), 436–446. doi: 10.1002/cnma.201800509

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne,Sulfo-Cyanine7.5 是一种近红外磺化花青染料，具有刚性化的三亚甲基链。 荧光团在结构上与已获准供人类使用的吲哚菁绿 (ICG) 染料非常相似。 然而，由于其刚性结构，染料具有改进的量子产率。

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  • Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne

标签：Alkynes, Near infrared (NIR) imaging, sulfo-Cyanine7.5,Cy7.5
货号 规格 价格 货期
A63B0 1 mg 110.00$ in stock
B63B0 5 mg 290.00$ in stock
C63B0 10 mg 470.00$ in stock
D63B0 25 mg 690.00$ in stock
E63B0 50 mg 1270.00$ in stock
F63B0 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a near infrared, sulfonated cyanine dye with rigidized trimethylene chain. The fluorophore is structurally very similar to indocyanine green (ICG) dye that has been approved for human use. However, the dye has an improved quantum yield because of its rigidized structure.

This is an alkyne derivative for copper catalyzed Click chemistry.

Sulfo-Cyanine7.5 是一种近红外磺化花青染料，具有刚性化的三亚甲基链。 荧光团在结构上与已获准供人类使用的吲哚菁绿 (ICG) 染料非常相似。 然而，由于其刚性结构，染料具有改进的量子产率。

这是一种用于铜催化点击化学的炔烃衍生物。

Absorption and emission spectra of sulfo-Cyanine7.5

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne相关产品

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Sulfo-Cyanine7.5 NHS ester

A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.

一种用于体内成像应用的水溶性近红外发射染料。 Sulfo-Cyanine7.5 是吲哚菁绿 (ICG) 的类似物，具有更高的发射量子产率，并包含一个连接臂。

sulfo-Cyanine7 dicarboxylic acid

Sulfo-Cyanine7 dicarboxylic acid is a bifunctional dye with two carboxyl groups.

Sulfo-Cyanine7 二羧酸是一种具有两个羧基的双功能染料。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1005.2
Molecular weight: 1120.46
Molecular formula: C48H48N3K3O13S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Sulfo-Cyanine7 alkyne

Sulfo-Cyanine7 alkyne,Sulfo-Cy7 炔烃是用于铜催化点击化学反应的磺化末端炔烃，具有显着的水溶性，可在水环境中与叠氮化物共轭。

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  • Sulfo-Cyanine7 alkyne

Sulfo-Cyanine7 alkyne

标签：sulfo-Cyanine7, Cy7,Alkynes
货号 规格 价格 货期
A53B0 1 mg 110.00$ in stock
B53B0 5 mg 290.00$ in stock
C53B0 10 mg 470.00$ in stock
D53B0 25 mg 690.00$ in stock
E53B0 50 mg 1270.00$ in stock
F53B0 100 mg 1990.00$ in stock

Sulfo-Cyanine7 alkyne is a sulfonated terminal alkyne for copper-catalyzed Click chemistry reaction, which possesses significant aqueous solubility, and can be conjugated with azides in aqueous environment.

Sulfo-Cy7 炔烃是用于铜催化点击化学反应的磺化末端炔烃，具有显着的水溶性，可在水环境中与叠氮化物共轭。

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 alkyne

Sulfo-Cyanine7 alkyne相关产品

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.

Cy3 炔烃是一种用于 Click Chemistry 的荧光染料炔烃。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cy5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

dsGreen for Real-Time PCR, 100×

Stock solution of dsGreen for Real-Time PCR, 100×

用于实时 PCR 的 dsGreen 储备溶液，100×

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 745.3
Molecular weight: 784.04
CAS number: 2183440-56-2
Molecular formula: C40H46N3KO7S2
Solubility: good in DMF, DMSO, significant in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne,Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基，具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

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  • Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne

标签：Alkynes, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A73B0 1 mg 110.00$ in stock
B73B0 5 mg 290.00$ in stock
C73B0 10 mg 470.00$ in stock
D73B0 25 mg 690.00$ in stock
E73B0 50 mg 1270.00$ in stock
F73B0 100 mg 1990.00$ in stock
Sulfo-Cyanine5.5 is a far red emitting fluorophore. It contains four sulfo groups, which provide great hydrophilicity, and aqueous solubility. The reagent can be conjugated with a variety of azides by means of copper catalyzed Click chemistry reaction.
Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基，具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne相关产品

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR（近红外）染料叠氮化物，适用于铜催化和无铜点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 1054.36
Molecular formula: C43H42N3K3O13S4
IUPAC name: (E)-4-[(2E,4E)-5-{3,3-Dimethyl-5-[6-oxo-6-(2-propynylamino)hexyl]-10-(oxysulfonyl)-12-sulfo-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid tripotassium salt
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne,用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

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  • Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

标签：sulfo-Cyanine5, Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A33B0 1 mg 110.00$ in stock
B33B0 5 mg 290.00$ in stock
C33B0 10 mg 470.00$ in stock
D33B0 25 mg 690.00$ in stock
E33B0 50 mg 1270.00$ in stock
F33B0 100 mg 1990.00$ in stock

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

该试剂推荐用于与蛋白质、纳米颗粒和亲水性很重要的其他应用结合。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的Cy5 胺官能化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团，但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3.5 alkyne

Sulfo-Cyanine3.5 alkyne,Cy3.5,Sulfo-Cyanine3.5 是一种在橙色光谱范围内具有荧光的染料（最大吸收波长为 576 nm；最大发射波长为 603 nm）。 其吸收和发射光谱介于花青 3 和花青 5 之间。 因此，Sulfo-Cyanine3.5 通常与 Cyanine5 成对用作 FRET 供体，与 Cy3 成对用作 FRET 受体，并用于 BRET 实验。

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  • Sulfo-Cyanine3.5 alkyne

Sulfo-Cyanine3.5 alkyne

标签：Alkynes, sulfo-Cyanine3.5,Cy3.5
货号 规格 价格 货期
A23B0 1 mg 110.00$ in stock
B23B0 5 mg 290.00$ in stock
C23B0 10 mg 470.00$ in stock
D23B0 25 mg 690.00$ in stock
E23B0 50 mg 1270.00$ in stock
F23B0 100 mg 1990.00$ in stock

Sulfo-Cyanine3.5 is a dye with fluorescence in the orange spectrum range (absorption maximum at 576 nm; emission maximum at 603 nm). Its absorption and emission spectra are between those of Cyanine3 and Cyanine5. Therefore, Sulfo-Cyanine3.5 is commonly used as a FRET-donor in a pair with Cyanine5, as a FRET-acceptor in a pair with Cyanine3, and in BRET experiments.

Sulfo-Cyanine3.5 is a sulfonated derivative with four sulfo groups, which allows its high hydrophilicity and performing all reactions with this reagent in aqueous solutions without adding organic solvents.

The reagent is an alkyne derivative of sulfo-Cyanine3.5 dye for copper-catalyzed Click chemistry. The terminal alkynyl (acetylene) group allows conjugating the fluorophore with the molecules containing an azide group through 1,3-dipolar cycloaddition in the presence of a copper(I) catalyst.

Sulfo-Cyanine3.5 是一种在橙色光谱范围内具有荧光的染料（最大吸收波长为 576 nm；最大发射波长为 603 nm）。 其吸收和发射光谱介于花青 3 和花青 5 之间。 因此，Sulfo-Cyanine3.5 通常与 Cyanine5 成对用作 FRET 供体，与 Cyanine3 成对用作 FRET 受体，并用于 BRET 实验。

Sulfo-Cyanine3.5 是一种具有四个磺基的磺化衍生物，具有高亲水性，可在不添加有机溶剂的情况下在水溶液中与该试剂进行所有反应。

该试剂是用于铜催化点击化学的磺基-Cyanine3.5 染料的炔烃衍生物。 末端炔基（乙炔）基团允许在铜 (I) 催化剂存在下通过 1,3-偶极环加成将荧光团与含有叠氮基的分子缀合。

Absorption and emission spectra of sulfo-Cyanine3.5

Sulfo-Cyanine3.5 alkyne

Sulfo-Cyanine3.5 alkyne相关产品

Sulfo-Cyanine3.5 azide

Azide derivative of water-soluble Sulfo-Cyanine3.5 dye for bioconjugation via Click Chemistry.

水溶性 Sulfo-Cyanine3.5 染料的叠氮化物衍生物，用于通过 Click Chemistry 进行生物共轭。

Sulfo-Cyanine3.5 NHS ester

Amine reactive activated ester of water soluble, sulfonated sulfo-Cyanine3.5 dye.

水溶性磺化磺化Cy3.5染料的胺活性活性酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 914.2
Molecular weight: 1028.32
Molecular formula: C41H40N3K3O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 576
ε, L⋅mol−1⋅cm−1: 139000
Emission maximum, nm: 603
Fluorescence quantum yield: 0.11
CF260: 0.16
CF280: 0.17

Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne,用于铜催化 Click Chemistry 的水溶性炔烃染料，是 Cy3® 炔烃的类似物。Sulfo-Cyanine3 是一种荧光团，与各种荧光扫描仪、成像仪、显微镜和其他仪器兼容。 它是一种明亮且光稳定的染料，在凝胶中也很容易通过肉眼检测到少量（<1 nmol）。

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  • Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne

标签：Alkynes, Microscopy, sulfo-Cyanine3,Cy3.5
货号 规格 价格 货期
A13B0 1 mg 110.00$ in stock 货号 规格 价格 货期
B13B0 5 mg 290.00$ in stock
C13B0 10 mg 470.00$ in stock
D13B0 25 mg 690.00$ in stock
E13B0 50 mg 1270.00$ in stock
F13B0 100 mg 1990.00$ in stock

A water soluble alkyne dye for copper catalyzed Click Chemistry, an analog of Cy3® alkyne.

Sulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, and other instrumentation. It is a bright and photostable dye, which is also easily detected in gels by naked eye in low amounts (<1 nmol).

用于铜催化 Click Chemistry 的水溶性炔烃染料，是 Cy3® 炔烃的类似物。

Sulfo-Cyanine3 是一种荧光团，与各种荧光扫描仪、成像仪、显微镜和其他仪器兼容。 它是一种明亮且光稳定的染料，在凝胶中也很容易通过肉眼检测到少量（<1 nmol）。

Absorbance and emission spectra of Sulfo-Cyanine3 dye

Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne相关产品

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

Sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.

水溶性磺基-Cy3 染料四嗪衍生物，用于用反式环辛烯进行 TCO 连接标记。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5&reg; channel.

用于 Cy5&reg; 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark red powder 暗红色粉末
Mass spec M+ increment: 653.2
Molecular weight: 691.90
CAS number: 2055138-87-7 (inner salt); 2055138-88-8 (sodium salt)
Molecular formula: C33H38KN3O7S2
Solubility: soluble in water (0.57 M = 40 g/L), DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献:

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  4. Sokolova, V.; Nzou, G.; van der Meer, S.B.; Ruks, T.; Heggen, M.; Loza, K.; Hagemann, N.; Murke, F.; Giebel, B.; Hermann, D.M.; Atala, A.J.; Epple, M. Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model. Acta Biomaterialia, 2020, 111, 349–362. doi: 10.1016/j.actbio.2020.04.023
Cy® is a trademark of GE Healthcare.

ROX alkyne, 5-isomer

ROX alkyne, 5-isomer,随着其量子产率接近统一，ROX 已成为 qPCR 和显微镜检查的流行染料。 这种明亮的荧光团可用作铜催化点击化学反应的炔烃。这是 ROX 的纯 5 异构体。

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  • ROX alkyne, 5-isomer

ROX alkyne, 5-isomer

标签：ROX (Rhodamine X, Rhodamine 101), Alkynes
货号 规格 价格 货期
A12B0 1 mg 110.00$ in stock
B12B0 5 mg 210.00$ in stock
C12B0 10 mg 310.00$ in stock
D12B0 25 mg 410.00$ in stock
E12B0 50 mg 695.00$ in stock
F12B0 100 mg 1190.00$ in stock

With its quantum yield approaching unity, ROX has become a popular dye for qPCR and microscopy. This bright fluorophore is available as an alkyne for copper-catalyzed Click chemistry reaction.

This is a pure 5-isomer of ROX.

ROX is prone to oxidation. Therefore, its derivatives should be preferably stored in inert atmosphere.

随着其量子产率接近统一，ROX 已成为 qPCR 和显微镜检查的流行染料。 这种明亮的荧光团可用作铜催化点击化学反应的炔烃。

这是 ROX 的纯 5 异构体。

ROX容易氧化。 因此，其衍生物应优选储存在惰性气氛中。

Absorption and emission spectra of ROX

ROX alkyne, 5-isomer

ROX alkyne, 5-isomer相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cyanine3 染料 NHS 酯。

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

R6G alkyne, 6-isomer

R6G (rhodamine 6G) terminal alkyne for copper catalyzed Click chemistry reaction with azides. Pure 6-isomer of the dye.

R6G（罗丹明 6G）末端炔烃用于铜催化与叠氮化物的点击化学反应。 染料的纯 6-异构体。

General properties

Appearance: purple solid 紫色固体
Mass spec M+ increment: 571.3
Molecular weight: 571.66
CAS number: 2264016-88-6
Molecular formula: C36H33N3O4
Solubility: good in DMSO, DMF, methanol, ethanol
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.00

R6G alkyne, 6-isomer

R6G alkyne, 6-isomer,罗丹明6G（R6G）是罗丹明系列的呫吨染料。 与荧光素相比，它的发射变为红色。 它也更耐光。 荧光团具有高量子产率。该 R6G 产品包含一个末端炔烃部分，用于在铜 (I) 催化剂存在下与叠氮化物结合。

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  • R6G alkyne, 6-isomer

R6G alkyne, 6-isomer

标签：Alkynes, R6G
货号 规格 价格 货期
A52B0 1 mg 110.00$ in stock
B52B0 5 mg 210.00$ in stock
C52B0 10 mg 310.00$ in stock
D52B0 25 mg 410.00$ in stock
E52B0 50 mg 695.00$ in stock
F52B0 100 mg 1190.00$ in stock

Rhodamine 6G (R6G) is a xanthene dye of rhodamine series. Compared to fluorescein, its emission is shifted to red. It is also much more photostable. The fluorophore has a high quantum yield.

This R6G product contains a terminal alkyne moiety for the conjugation with azides in the presence of copper (I) catalyst.

罗丹明6G（R6G）是罗丹明系列的呫吨染料。 与荧光素相比，它的发射变为红色。 它也更耐光。 荧光团具有高量子产率。

该 R6G 产品包含一个末端炔烃部分，用于在铜 (I) 催化剂存在下与叠氮化物结合。

Absorption and emission spectra of 6-R6G

R6G alkyne, 6-isomer

R6G alkyne, 6-isomer相关产品

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

ROX alkyne, 5-isomer

Rhodamine X (ROX, Rhodamine 101) alkyne derivative for copper catalyzed Click chemistry. ROX is a bright red-emitting dye.

用于铜催化点击化学的罗丹明 X（ROX，罗丹明 101）炔烃衍生物。 ROX 是一种明亮的红色发射染料。

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃，纯 6 异构体。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 494.2
Molecular weight: 495.57
Molecular formula: C30H29N3O4
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 518
ε, L⋅mol−1⋅cm−1: 116000
Emission maximum, nm: 542
Fluorescence quantum yield: 0.95
CF260: 0.18
CF280: 0.17

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Gao, F.; Hunter, A.; Qu, S.; Hoffman, J.R.; Gao, P.; Phillip, W.A. Interfacial Junctions Control Electrolyte Transport Through Charge-Patterned Membranes. ACS Nano, 2019, 13(7), 7655–7664. doi: 10.1021/acsnano.9b00780

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer,用于 Click Chemistry 的 FAM（荧光素）荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。荧光素是一种明亮的荧光团，与许多不同的荧光仪器兼容。

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  • FAM alkyne, 6-isomer

FAM alkyne, 6-isomer

标签：FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A51B0 1 mg 80.00$ in stock
B51B0 5 mg 100.00$ in stock
C51B0 10 mg 150.00$ in stock
D51B0 25 mg 295.00$ in stock
E51B0 50 mg 450.00$ in stock
F51B0 100 mg 780.00$ in stock

Alkyne derivative of FAM (fluorescein) fluorophore for Click Chemistry. Pure (97+%) single 6-isomer.

Fluorescein is a bright fluorophore which is compatible with a number of different fluorescent instruments.

用于 Click Chemistry 的 FAM（荧光素）荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。

荧光素是一种明亮的荧光团，与许多不同的荧光仪器兼容。

FAM absorbance and emission spectra

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer相关产品

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.

用于点击化学的 TAMRA 荧光染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 478801-49-9
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献：

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer,用于铜催化点击化学的 FAM（荧光素）炔烃，高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

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  • FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

标签：FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A41B0 1 mg 80.00$ in stock
B41B0 5 mg 100.00$ in stock
C41B0 10 mg 150.00$ in stock
D41B0 25 mg 295.00$ in stock
E41B0 50 mg 450.00$ in stock
F41B0 100 mg 780.00$ in stock

FAM (fluorescein) alkyne for copper-catalyzed Click chemistry, high purity (97+%) 5-isomer. The compound possesses significant aqueous solubility.

用于铜催化点击化学的 FAM（荧光素）炔烃，高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

FAM absorbance and emission spectra

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cyanine5 荧光团的远红通道。

Sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3 analog.

Sulfo-Cyanine3 的水溶性硫醇反应性衍生物，一种 Cy3 类似物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 510758-19-7
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
  3. Sokolova, V.; Mekky, G.; van der Meer, S.B.; Seeds, M.C.; Atala, A.J.; Epple, M. Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Scientific Reports, 2020, 10, 18033. doi: 10.1038/s41598-020-75125-2
  4. Warminski, M.; Kowalska, J.; Jemielity, J. Solid-Phase Synthesis of RNA 5′-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry. Current Protocols in Nucleic Acid Chemistry, 2020, 82(1), e112. doi: 10.1002/cpnc.112

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Cyanine7.5 alkyne

Cyanine7.5 alkyne,Cy7.5 的炔烃衍生物，一种近红外荧光团。 该炔烃适用于铜催化的点击化学。这种荧光团可用于体内成像，其光谱特性与 ICG（吲哚菁绿）相似，具有更高的荧光量子产率。

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  • Cyanine7.5 alkyne

Cyanine7.5 alkyne

标签：Cyanine7.5,Cy7.5, Alkynes, Near infrared (NIR) imaging
货号 规格 价格 货期
A60B0 1 mg 110.00$ in stock
B60B0 5 mg 210.00$ in stock
C60B0 10 mg 310.00$ in stock
D60B0 25 mg 410.00$ in stock
E60B0 50 mg 695.00$ in stock
F60B0 100 mg 1190.00$ in stock

Alkyne derivative of Cyanine7.5, a near infrared fluorophore. This alkyne is suitable for copper-catalyzed Click Chemistry.

This fluorophore is useful for in vivo imaging, its spectral properties are similar to ICG (indocyanine green) with somewhat higher fluorescence quantum yield.

Cyanine7.5 的炔烃衍生物，一种近红外荧光团。 该炔烃适用于铜催化的点击化学。

这种荧光团可用于体内成像，其光谱特性与 ICG（吲哚菁绿）相似，具有更高的荧光量子产率。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 alkyne

Cyanine7.5 alkyne相关产品

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素（一种众所周知的亲和探针）进行点击化学标记的试剂。

Cyanine7.5 carboxylic acid

Cyanine7.5 – unactivated NIR cyanine dye carboxylic acid.

Cy7.5 – 未活化的近红外花青染料羧酸。

R6G alkyne, 6-isomer

R6G (rhodamine 6G) terminal alkyne for copper catalyzed Click chemistry reaction with azides. Pure 6-isomer of the dye.

R6G（罗丹明 6G）末端炔烃用于铜催化与叠氮化物的点击化学反应。 染料的纯 6-异构体。

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 686.4
Molecular weight: 722.40
Molecular formula: C48H52ClN3O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献：

  1. Chan, P.S.; Xian, J.W.; Li, Q.; Chan, C.W.; Leung, S.S.Y.; To, K.K.W. Biodegradable Thermosensitive PLGA-PEG-PLGA Polymer for Non-irritating and Sustained Ophthalmic Drug Delivery. AAPS Journal, 2019, 21, 59. doi: 10.1208/s12248-019-0326-x
Cy® is a trademark of GE Healthcare.

Cyanine7 alkyne

Cyanine7 alkyne,Cyanine7 的炔烃衍生物，一种近红外荧光团，Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。该染料在水中的溶解度有限，但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

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  • Cyanine7 alkyne

Cyanine7 alkyne

标签：Cyanine7, Cy7,Alkynes, Near infrared (NIR) imaging
货号 规格 价格 货期
A50B0 1 mg 110.00$ in stock
B50B0 5 mg 210.00$ in stock
C50B0 10 mg 310.00$ in stock
D50B0 25 mg 410.00$ in stock
E50B0 50 mg 695.00$ in stock
F50B0 100 mg 1190.00$ in stock

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry.

The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

Cyanine7 的炔烃衍生物，一种近红外荧光团，Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。

该染料在水中的溶解度有限，但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

Cyanine7 absorbance and emission spectra

Cyanine7 alkyne

Cyanine7 alkyne相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cy5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 586.4
Molecular weight: 622.28
CAS number: 1998119-13-3 (chloride), 1954687-62-7
Molecular formula: C40H48ClN3O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  2. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  3. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  4. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
Cy® is a trademark of GE Healthcare.