分类： 染料马来酰亚胺 Dye maleimides

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide,sulfo-Cyanine7.5 是一种近红外荧光团，吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式，这是一种马来酰亚胺，用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

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  • sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide

标签：Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine7.5, Cy7.5
货号 规格 价格 货期
16380 1 mg 110.00$ in stock
26380 5 mg 290.00$ in stock
46380 25 mg 690.00$ in stock
56380 50 mg 1270.00$ in stock
66380 100 mg 1990.00$ in stock

sulfo-Cyanine7.5 is a near infrared fluorophore with absorption and emission ranges around 800 nm. Its spectral properties allow for the efficient leveraging of tissue NIR transparency window. The fluorophore is available as different reactive forms, this one is maleimide for the labeling of SH groups of proteins and peptides. The sulfo- version is highly hydrophilic.

Such labeled biomolecules are useful in biodistribution studies and visualization in intact organisms.

sulfo-Cyanine7.5 是一种近红外荧光团，吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式，这是一种马来酰亚胺，用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

这种标记的生物分子可用于生物分布研究和完整生物体的可视化。

Absorption and emission spectra of sulfo-Cyanine7.5

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

TAMRA maleimide, 6-isomer

TAMRA is a well known xanthene dye of rhodamine series. This is a thiol reactive maleimide for the labeling of SH groups in proteins and peptides. Pure 6-isomer.

TAMRA 是众所周知的罗丹明系列呫吨染料。 这是一种硫醇反应性马来酰亚胺，用于标记蛋白质和肽中的 SH 基团。 纯 6 异构体。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1090.3
Molecular weight: 1205.52
Molecular formula: C51H51N4K3O15S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer,TAMRA（也称为 TMR 或四甲基罗丹明）是一种呫吨染料，几十年来一直被用作荧光标记。

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  • TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer

标签：Maleimides, TAMRA (TMR, tetramethylrhodamine)
货号 规格 价格 货期
18180 1 mg 110.00$ in stock
28180 5 mg 210.00$ in stock
48180 25 mg 410.00$ in stock
58180 50 mg 695.00$ in stock
68180 100 mg 1190.00$ in stock

TAMRA (also known as TMR or tetramethylrhodamine) is a xanthene dye that has been used as a fluorescent label for decades. Xanthene dyes are available as two isomers (called 5- and 6-isomers) that have almost identical fluorescent properties, but need to be separated to avoid doubling and smearing of labeled product peaks or bands during chromatography or electrophoresis. This is a pure 6-isomer of TAMRA maleimide, used for the labeling of proteins and peptides via thiol (SH) groups.

TAMRA（也称为 TMR 或四甲基罗丹明）是一种呫吨染料，几十年来一直被用作荧光标记。 呫吨染料有两种异构体（称为 5 异构体和 6 异构体），它们具有几乎相同的荧光特性，但需要分离以避免在色谱或电泳过程中标记的产物峰或带加倍和拖尾。 这是 TAMRA 马来酰亚胺的纯 6 异构体，用于通过硫醇 (SH) 基团标记蛋白质和肽。

Absorption and emission spectra of 6-TAMRA

TAMRA maleimide, 6-isomer

TAMRA maleimide, 6-isomer相关产品

BDP R6G NHS ester

BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.

BDP R6G 是一种硼二吡咯亚甲基染料，其吸收和发射光谱与 R6G 相似。

TAMRA NHS ester, 5-isomer

Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.

TAMRA 染料的胺反应活性 N-羟基琥珀酰亚胺酯，用于标记蛋白质、肽和氨基寡核苷酸的胺基。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 551.2
Molecular weight: 552.58
Molecular formula: C31H28N4O6
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

相关文献：

  1. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
  2. Sagert, L.; Hennig, F.; Thomas, C.; Tampé, R. A loop structure allows TAPBPR to exert its dual function as MHC I chaperone and peptide editor. eLife, 2020, 9, e55326. doi: 10.7554/eLife.55326
  3. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.; Koszegi, Z.; Bacon, A.; Jones, B.J.; Lucey, M.A.; Sasaki, S.; Brierley, D.I.; Hastoy, B.; Tomas, A.; D’Agostino, G.; Reimann, F.; Lynn, F.C.; Reissaus, C.A.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Trapp, S.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 2020, 11, 467. doi: 10.1038/s41467-020-14309-w

TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer,TAMRA（四甲基罗丹明）的马来酰亚胺衍生物，用于标记硫醇基团。 TAMRA 的纯 5-异构体。

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  • TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer

标签：Maleimides, TAMRA (TMR, tetramethylrhodamine)
17180 1 mg 110.00$ in stock
27180 5 mg 210.00$ in stock
47180 25 mg 410.00$ in stock
57180 50 mg 695.00$ in stock
67180 100 mg 1190.00$ in stock

Maleimide derivative of TAMRA (tetramethylrhodamine) for the labeling of thiol groups. Pure 5-isomer of TAMRA.

TAMRA（四甲基罗丹明）的马来酰亚胺衍生物，用于标记硫醇基团。 TAMRA 的纯 5-异构体。

Absorption and emission spectra of 5-TAMRA

TAMRA maleimide, 5-isomer

TAMRA maleimide, 5-isomer相关产品

FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

AF430 NHS ester

AF430 is a hydrophilic coumarin dye with the emission in green-yellow range. The NHS ester is used for the labeling of amine groups.

AF430 是一种亲水性香豆素染料，发射在黄绿色范围内。 NHS 酯用于标记胺基。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: red powder  红色粉末
Mass spec M+ increment: 552.2
Molecular weight: 552.58
Molecular formula: C31H28N4O6
IUPAC name: 1-[2-({3′,6′-Bis(dimethylamino)-3-oxospiro[isobenzofuran-1,9′-xanthen]-5-yl}carbonylamino)ethyl]-1H-pyrrole-2,5-dione
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide,一种带有马来酰亚胺基团的活性染料，用于标记蛋白质和其他生物分子的硫醇基团，是 Cy7® 马来酰亚胺的类似物。

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  • Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide

标签：sulfo-Cyanine7, Cy7,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15380 1 mg 110.00$ in stock
25380 5 mg 290.00$ in stock
45380 25 mg 690.00$ in stock
55380 50 mg 1270.00$ in stock
65380 100 mg 1990.00$ in stock

A reactive dye with a maleimide group for the labeling of thiol groups of proteins and other biomolecules, an analog of Cy7® maleimide.

Sulfo-Cyanine7 is a near infrared fluorophore which is hydrophilic and contains a rigidizing ring in its heptamethine chain that improves its photophysical properties. A great dye for various applications, including NIR imaging.

一种带有马来酰亚胺基团的活性染料，用于标记蛋白质和其他生物分子的硫醇基团，是 Cy7® 马来酰亚胺的类似物。

Sulfo-Cyanine7 是一种近红外荧光团，具有亲水性，在其七甲碱链中包含一个刚性环，可改善其光物理性质。 适用于各种应用的出色染料，包括 NIR 成像。

Sulfo-Cyanine7 maleimide absorbance and emission spectra

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Cyanine7.5 maleimide

Cyanine7.5 maleimide is a thiol reactive near infrared dye.

Cy7.5 马来酰亚胺是一种硫醇活性近红外染料。

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的花青5 胺官能化染料。

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 868.2
Molecular weight: 869.10
CAS number: 2183440-60-8 (potassium salt), 2183440-59-5 (inner salt)
Molecular formula: C43H49KN4O9S2
IUPAC name: 1-[2-(6-{2-[(E)-2-[(E)-3-{(E)-2-[1-Methyl-3,3-dimethyl-5-(oxysulfonyl)-2-indolinylidene]ethylidene}-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-(oxysulfonyl)-3H-indol-1-yl}hexanoylamino)ethyl]-1H-pyrrole-2,5-dione, potassium salt
Solubility: Good in water, DMF, DMSO. Low in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献：

  1. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, in press. doi: 10.1021/acs.chemmater.1c02844
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide,Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

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  • Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide

标签：Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17380 1 mg 110.00$ in stock
27380 5 mg 290.00$ in stock
47380 25 mg 690.00$ in stock
57380 50 mg 1270.00$ in stock
67380 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案，应使用适当的还原剂（例如 TCEP）还原天然蛋白质的二硫键。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

BDP TMR maleimide

A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.

用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定，以及其他应用。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献：

  1. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  2. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide,水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

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  • Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide

标签：sulfo-Cyanine5, Cy5,Maleimides, Microscopy
货号 规格 价格 货期
13380 1 mg 110.00$ in stock
23380 5 mg 290.00$ in stock
43380 25 mg 690.00$ in stock
53380 50 mg 1270.00$ in stock
63380 100 mg 1990.00$ in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

也可使用不含磺基的类似物 Cyanine5 马来酰亚胺。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide相关产品

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

ROX NHS ester, 6- isomer

Pure isomer 6-ROX NHS ester for amine labeling.

用于胺标记的纯异构体 6-ROX NHS 酯。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark blue powder  深蓝色粉末
Molecular weight: 803.00
CAS number: 2242791-82-6
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide,Sulfo-Cy3 马来酰亚胺是一种水溶性硫醇活性染料，可用于标记亲水性磺基-Cyanine3 荧光团。 这是 Cy3® 马来酰亚胺的类似物。

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  • Reactive dyes
  • Dye maleimides
  • Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

标签：Maleimides, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
11380 1 mg 110.00$ in stock
21380 5 mg 290.00$ in stock
41380 25 mg 690.00$ 5 days
51380 50 mg 1270.00$ in stock
61380 100 mg 1990.00$ in stock

Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3® maleimide.

This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.

A non-sulfonated Cyanine3 maleimide is available.

Sulfo-Cyanine3 马来酰亚胺是一种水溶性硫醇活性染料，可用于标记亲水性磺基-Cyanine3 荧光团。 这是 Cy3® 马来酰亚胺的类似物。

该产品推荐用于在温和的纯水性条件下标记抗体和其他不稳定的蛋白质。 该染料是水溶性的，不需要使用有机助溶剂。

可使用非磺化的 Cyanine3 马来酰亚胺。

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide

Sulfo-Cyanine3 maleimide相关产品

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cyanine3 SE 活化酯。

General properties

Appearance: red powder 红色粉末
Molecular weight: 776.96
CAS number: 1656990-68-9
Molecular formula: C36H41KN4O9S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt, potassium salt
Solubility: soluble in water (0.39 M = 30 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, 2021, 49(5), 2450–2459. doi: 10.1093/nar/gkab040
Cy® is a trademark of GE Healthcare.

ROX maleimide, 5-isomer

ROX maleimide, 5-isomer,ROX 是一种明亮的罗丹明染料，最大发射波长约为 580 nm。 它广泛用于标记生物分子。 与其他罗丹明染料一样，它有两种异构体，5-ROX 和 6-ROX。 尽管这些异构体具有几乎相同的光谱特性，但需要将它们分离以避免在 HPLC 或电泳中标记产物加倍。

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  • ROX maleimide, 5-isomer

ROX maleimide, 5-isomer

标签：ROX (Rhodamine X, Rhodamine 101), Maleimides
货号 规格 价格 货期
11280 1 mg 110.00$ in stock
21280 5 mg 210.00$ in stock
41280 25 mg 410.00$ in stock
51280 50 mg 695.00$ in stock
61280 100 mg 1190.00$ in stock

ROX is a bright rhodamine dye with emission maximum around 580 nm. It is widely used for the labeling of biomolecules. As other rhodamine dyes, it comes as two isomers, 5-ROX and 6-ROX. Although these isomers have almost identical spectral properties, they need to be separated to avoid doubling of labeled products on HPLC or electrophoresis.

This derivative contains thiol-reactive maleimide moiety for the attachment of ROX fluorophore to SH groups, such as cystein residues in proteins and peptides.

ROX 是一种明亮的罗丹明染料，最大发射波长约为 580 nm。 它广泛用于标记生物分子。 与其他罗丹明染料一样，它有两种异构体，5-ROX 和 6-ROX。 尽管这些异构体具有几乎相同的光谱特性，但需要将它们分离以避免在 HPLC 或电泳中标记产物加倍。

该衍生物含有硫醇反应性马来酰亚胺部分，用于将 ROX 荧光团连接到 SH 基团，例如蛋白质和肽中的半胱氨酸残基。

Absorption and emission spectra of ROX

ROX maleimide, 5-isomer

ROX maleimide, 5-isomer相关文献

BDP R6G maleimide

BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.

BDP R6G 是一种调谐到 R6G（罗丹明 6G）通道的硼二吡咯亚甲基染料。 这是一种硫醇反应性马来酰亚胺，用于标记蛋白质半胱氨酸残基和其他硫醇。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

General properties

Appearance: red powder  红色粉末
Mass spec M+ increment: 656.3
Molecular weight: 656.73
Molecular formula: C39H36N4O6
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.00

Pyrene maleimide

Pyrene maleimide,Pyrene 是一种在蓝色区域发射的荧光碳氢化合物。 这是与硫醇反应的芘丁酸的马来酰亚胺衍生物。

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  • Pyrene maleimide

Pyrene maleimide

标签：Maleimides, Pyrene
货号 规格 价格 货期
13580 1 mg 110.00$ in stock
23580 5 mg 210.00$ in stock
43580 25 mg 410.00$ in stock
53580 50 mg 695.00$ in stock
63580 100 mg 1190.00$ in stock

Pyrene is a fluorescent hydrocarbon which emits in blue region. This is a maleimide derivative of pyrenebutyric acid which reacts with thiols.

Pyrene is a useful proximity probe because two pyrene residues close to each other exhibit strong excimer fluorescence.

Pyrene 是一种在蓝色区域发射的荧光碳氢化合物。 这是与硫醇反应的芘丁酸的马来酰亚胺衍生物。

Pyrene 是一种有用的邻近探针，因为彼此靠近的两个芘残基表现出强烈的准分子荧光。

Absorption and emission spectra of pyrene fluorophore

Pyrene maleimide

Pyrene maleimide相关产品

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

氨基反应性 BDP FL，一种非常明亮且光稳定的荧光素通道染料。

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling

用于蛋白质标记的 Cy2 NHS 酯最小染料

BDP FL maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy.

BDP FL 马来酰亚胺是一种用于蛋白质标记的明亮且光稳定的硫醇反应性染料，是显微镜下荧光素的理想替代品。

General properties

Appearance: off white solid 灰白色固体
Mass spec M+ increment: 410.2
Molecular weight: 410.46
CAS number: 1869968-64-8
Molecular formula: C26H22N2O3
Solubility: well soluble in chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer,FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

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  • FAM maleimide, 6-isomer

FAM maleimide, 6-isomer

标签：FAM (Fluorescein), Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
24180 5 mg – in stock
44180 25 mg 160.00$ in stock
54180 50 mg 270.00$ in stock
64180 100 mg 420.00$ in stock

FAM (fluorescein) is a bright fluorophore which is compatible with various fluorescence detection instruments. FAM is a universal dye that is useful for microscopy, qPCR and many other methods as well as for FRET-based and fluorescence polarization based binding assays.

FAM maleimide is a thiol reactive dye for the labeling of proteins, peptides, and other thiolated molecules.

FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

FAM 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质、肽和其他硫醇化分子。

Fluorescein (FAM) absorbance and emission spectra

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer相关产品

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物，用于 FAM（荧光素）488 nm 通道的硼二吡咯亚甲基染料。

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR（近红外）染料叠氮化物，适用于铜催化和无铜点击化学。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 498.4
Molecular weight: 498.44
Molecular formula: C27H18N2O8
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  2. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  3. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  4. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680

Cyanine7.5 maleimide

Cyanine7.5 maleimide,硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团，Cy7.5® 马来酰亚胺的类似物。

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  • Cyanine7.5 maleimide

Cyanine7.5 maleimide

标签：Cyanine7.5, Cy7.5,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
16080 1 mg 110.00$ in stock
26080 5 mg 210.00$ in stock
46080 25 mg 410.00$ 5 days
56080 50 mg 695.00$ in stock
66080 100 mg 1190.00$ in stock

Thiol-reactive, near infrared dye Cyanine7.5 for the labeling of protein SH groups, an analog of Cy7.5® maleimide.

Most proteins contain sulfhydryl groups which can be selectively labeled with maleimides. With this reagent, these proteins can be converted to near infrared (NIR) fluorescent conjugates. After it, the conjugates can be used in non-invasive live organism imaging to study distribution of the protein in tissues and organs.

硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团，Cy7.5® 马来酰亚胺的类似物。

大多数蛋白质含有巯基，可以选择性地用马来酰亚胺标记。 使用该试剂，这些蛋白质可以转化为近红外 (NIR) 荧光结合物。 之后，缀合物可用于非侵入性活体生物成像，以研究蛋白质在组织和器官中的分布。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 maleimide

Cyanine7.5 maleimide相关产品

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cyanine7 NHS 酯是一种水溶性、近红外、胺反应性染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: green powder  绿色粉末
Molecular weight: 807.46
Molecular formula: C51H55ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献：

  1. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
Cy® is a trademark of GE Healthcare.

Cyanine7 maleimide

Cyanine7 maleimide,近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

  • Products
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  • Cyanine7 maleimide

Cyanine7 maleimide

标签：Cyanine7,Cy7, Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15080 1 mg 110.00$ in stock
25080 5 mg 210.00$ in stock
45080 25 mg 410.00$ in stock
55080 50 mg 695.00$ in stock
65080 100 mg 1190.00$ in stock

Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。

该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

Cyanine7 absorbance and emission spectra

Cyanine7 maleimide

Cyanine7 maleimide相关产品

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

用于 TCO 连接的含有四嗪基团的近红外 Cy7 染料衍生物。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 707.34
CAS number: 2120392-49-4 (without anion)
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  2. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  3. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  4. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
Cy® is a trademark of GE Healthcare.

Cyanine5.5 maleimide

Cyanine5.5 maleimide,Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

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  • Reactive dyes
  • Dye maleimides
  • Cyanine5.5 maleimide

Cyanine5.5 maleimide

标签：Cyanine5.5, Cy5.5,Maleimides, Microscopy
货号 规格 价格 货期
17080 1 mg 110.00$ 5 days
27080 5 mg 210.00$ in stock
47080 25 mg 410.00$ in stock
57080 50 mg 695.00$ in stock
67080 100 mg 1190.00$ in stock

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

Cyanine5.5 的近红外发射使这种染料适用于生物成像应用。

Cyanine5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 maleimide

Cyanine5.5 maleimide相关产品

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cyanine5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

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get free express delivery

Cyanine7.5 azide

Long-wavelength NIR fluorescent dye azide for Click chemistry.

用于点击化学的长波长 NIR 荧光染料叠氮化物。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 741.36
CAS number: 1593644-50-8
Molecular formula: C46H49ClN4O3
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508
  2. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  3. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  4. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383

Show more (15)

Cy® is a trademark of Cytiva.

Cyanine5 maleimide

Cyanine5 maleimide,Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

  • Products
  • Reactive dyes
  • Dye maleimides
  • Cyanine5 maleimide

Cyanine5 maleimide

标签：Cyanine5,Cy5, Maleimides, Microscopy
货号 规格 价格 货期
13080 1 mg 110.00$ in stock
23080 5 mg 210.00$ in stock
43080 25 mg 410.00$ in stock
53080 50 mg 695.00$ in stock
63080 100 mg 1190.00$ in stock

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates.

Cyanine5 is an analog of Cy5®, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers.

For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.

Cy5 马来酰亚胺是一种单反应性染料，可选择性地与硫醇基团（例如，与肽和蛋白质中的半胱氨酸）偶联，形成标记的偶联物。

Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

对于抗体和敏感蛋白的标记，我们建议使用水溶性磺基-Cyanine5 马来酰亚胺。

Cy5 excitation and emission spectra

Cyanine5 maleimide

Cyanine5 maleimide相关产品

FAM hydrazide, 5-isomer

FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.

FAM 酰肼是一种羰基反应性荧光素衍生物。 纯5-异构体。 可以用羰基标记氧化的蛋白质、糖类和许多小分子。

Cyanine5 maleimide Add this product to your cart and
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Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 605.8
CAS number: 1437872-46-2 (without anion)
Molecular formula: C38H45N4O3
IUPAC name: 3H-​Indolium, 2-​[5-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​3,​3-​trimethyl-
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Pishesha, N.; Harmand, T.; Smeding, L.; Ma, W.; Ludwig, L.; Janssen, R.; Islam, A.; Xie, Y.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H.; Ploegh, H. Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance. Research Square, preprint. doi: 10.21203/rs.3.rs-192181/v1
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  4. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
Cy® is a trademark of GE Healthcare.

Cyanine3 maleimide

Cyanine3 maleimide,硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cy3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

  • Products
  • Reactive dyes
  • Dye maleimides
  • Cyanine3 maleimide

Cyanine3 maleimide

标签：Cyanine3, Cy3,Maleimides, Microscopy
货号 规格 价格 货期
11080 1 mg 110.00$ in stock
21080 5 mg 210.00$ in stock
41080 25 mg 410.00$ in stock
51080 50 mg 695.00$ in stock
61080 100 mg 1190.00$ in stock

Thiol mono-reactive Cyanine3 dye. This reagent can be used to attach Cyanine3 fluorophore (an analog of Cy3®) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides).

Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or other appropriate reductant prior to the labeling.

Labeling with Cyanine3 maleimide is selective, and efficient.

We recommend using water-soluble Sulfo-Cyanine3 maleimide for the labeling of antibodies and other sensitive proteins.

硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cyanine3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

标记前应使用 TCEP（三羧乙基膦）或其他合适的还原剂还原胱氨酸。

用 Cyanine3 马来酰亚胺标记具有选择性且有效。

我们建议使用水溶性 Sulfo-Cyanine3 马来酰亚胺标记抗体和其他敏感蛋白。

Cy3 absorbance and emission spectra

Cyanine3 maleimide

Cyanine3 maleimide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

Sulfo-Cyanine3 carboxylic acid

Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.

Sulfo-Cyanine3 不含未活化的单官能羧酸，水溶性染料。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

General properties

Appearance: red powder  红色粉末
Molecular weight: 666.56
Molecular formula: C36H43N4O3BF4
Solubility: well soluble in DMSO (0.50 M = 330 g/L), in DMF, dichloromethane, very poorly soluble in water (0.57 mM = 420 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  2. Budiardjo, S.J.; Deay, J.J.; Calkins, A.L.; Wimalasena, V.K.; Montezano, D.; Biteen, J.S.; Slusky, J.S.G. Colicin E1 Fragments Potentiate Antibiotics by Plugging TolC. bioRxiv, preprint. doi: 10.1101/692251
  3. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  4. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
Cy® is a trademark of GE Healthcare.

BDP TR maleimide

BDP TR maleimide,BDP TR 是一种吸收和发射类似于 ROX 的硼二吡咯亚甲基染料。 与ROX相比，其荧光量子产率和亮度要高得多。

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  • BDP TR maleimide

BDP TR maleimide

标签：Maleimides, BDP TR
货号 规格 价格 货期
13480 1 mg 110.00$ in stock
23480 5 mg 210.00$ in stock
43480 25 mg 410.00$ in stock
53480 50 mg 695.00$ in stock
63480 100 mg 1190.00$ in stock
BDP TR is a borondipyrromethene dye with absorption and emission similar to ROX. Compared to ROX, its fluorescence quantum yield and brightness is much higher.

Maleimide can be conjugated with thiol groups of proteins and peptides.

BDP TR 是一种吸收和发射类似于 ROX 的硼二吡咯亚甲基染料。 与ROX相比，其荧光量子产率和亮度要高得多。

马来酰亚胺可以与蛋白质和肽的硫醇基团结合。

Absorption and emission spectra of BDP TR

BDP TR maleimide

BDP TR maleimide相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

Coumarin 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是Coumarin 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 545.1
Molecular weight: 546.35
Molecular formula: C27H21N4BF2O4S
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19

BDP TMR maleimide

BDP TMR maleimide,BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

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  • BDP TMR maleimide

BDP TMR maleimide

标签：Maleimides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12480 1 mg 110.00$ in stock
22480 5 mg 210.00$ in stock
42480 25 mg 410.00$ in stock
52480 50 mg 695.00$ in stock
62480 100 mg 1190.00$ in stock

BDP TMR is a bright borondipyrromethene fluorophore for the TAMRA channel. This maleimide derivative is suitable for conjuction with thiol groups as e.g. in protein side chains.

BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

Absorption and emission spectra of BDP TMR

BDP TMR maleimide

BDP TMR maleimide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

BDP TR NHS ester

BDP TR is a borondipyrromethene dye. A bright and photostable fluorophore with high quantum yield.

BDP TR 是一种硼二吡咯亚甲基染料。 具有高量子产率的明亮且光稳定的荧光团。

General properties

Appearance: purple powder  紫色粉末
Mass spec M+ increment: 520.2
Molecular weight: 520.34
CAS number: 2183473-34-7
Molecular formula: C27H27BF2N4O4
IUPAC name: 2-(2-(N-maleimidoethylaminocarbonylethyl))-1,3-dimethyl-5-(4-methoxyphenyl)-4,4-difluoroborondipyrromethene
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献：

  1. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084

BDP R6G maleimide

BDP R6G maleimide,BDP R6G 是一种硼二吡咯亚甲基荧光团，其吸收和发射光谱与罗丹明 6G (R6G) 染料相匹配。

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  • BDP R6G maleimide

BDP R6G maleimide

标签：Maleimides, BDP R6G
货号 规格 价格 货期
14480 1 mg 110.00$ in stock
24480 5 mg 210.00$ in stock
44480 25 mg 410.00$ in stock
54480 50 mg 695.00$ in stock
64480 100 mg 1190.00$ in stock

BDP R6G is a borondipyrromethene fluorophore whose absorption and emission spectra match those of rhodamine 6G (R6G) dye.

Thiol labeling is often an option of choice for the modification of proteins. Limited number of cysteine residues in proteins allow for more site-specific labeling than NHS ester labeling of amine groups, which are encountered in large number in many proteins.

This maleimide is a thiol reactive dye. Please refer to our recommended labeling protocol to achieve modification of your protein with this reagent.

BDP R6G 是一种硼二吡咯亚甲基荧光团，其吸收和发射光谱与罗丹明 6G (R6G) 染料相匹配。

硫醇标记通常是蛋白质修饰的一种选择。 蛋白质中有限数量的半胱氨酸残基允许比 NHS 酯标记胺基团更多的位点特异性标记，这在许多蛋白质中大量遇到。

这种马来酰亚胺是一种硫醇活性染料。 请参考我们推荐的标记方案，以使用该试剂对您的蛋白质进行修饰。

Absorption and emission spectra of BDP R6G

BDP R6G maleimide

BDP R6G maleimide相关产品

BDP 650/665 maleimide

This maleimide is a thiol reactive derivative of BDP 650/665, a borondipyrromethene dye for Cyanine5 (Cy5) channel.

该马来酰亚胺是 BDP 650/665 的硫醇活性衍生物，BDP 650/665 是一种用于花青 5 (Cy5) 通道的硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: red or brown solid  红色或棕色固体
Mass spec M+ increment: 462.2
Molecular weight: 462.26
CAS number: 2183473-32-5
Molecular formula: C24H21N4BF2O3
IUPAC name: 1-Phenyl-6-(2-(2-(N-maleimido)ethylaminocarbonyl)ethyl)borondipyrromethene
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL maleimide

BDP FL maleimide,硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

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  • BDP FL maleimide

BDP FL maleimide

标签：BDP FL, Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11480 1 mg 110.00$ in stock
21480 5 mg 210.00$ in stock
41480 25 mg 410.00$ in stock
51480 50 mg 695.00$ in stock
61480 100 mg 1190.00$ in stock

Thiol reactive BDP FL maleimide is a reactive dye for protein labeling, which has identical structure with BODIPY® FL maleimide.

BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. Its brightness is similar to fluorescein, R110 and xanthene dye derivatives.

This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.

硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

BDP FL 是一种硼二吡咯亚甲基染料，其吸收光谱和荧光光谱与荧光素 (FAM) 相似。 然而，这种染料表现出非常高的光稳定性。 它是不带电的，并且具有低分子量。 其亮度类似于荧光素、R110 和呫吨染料衍生物。

这种荧光团是荧光显微镜和许多其他应用的理想选择。 荧光团几乎可以在任何应用中替代荧光素，并且与任何支持 FAM 的荧光仪器兼容。

Absorption and emission spectra of BDP FL

BDP FL maleimide

BDP FL maleimide相关产品

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

EDC, coupling grade

Water soluble carbodiimide for the coupling of carboxylic acids with amines.

用于羧酸与胺偶联的水溶性碳二亚胺。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

General properties

Appearance: orange solid  橙色固体
Mass spec M+ increment: 414.1
Molecular weight: 414.21
CAS number: 773859-49-7
Molecular formula: C20H21BF2N4O3
Solubility: Good in organic solvents (DMF, DMSO), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  2. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  3. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  4. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
BODIPY® is a trademark of Life Technologies.

BDP 650/665 maleimide

BDP 650/665 maleimide,BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性，但可用于标记水环境中的生物分子，因此是 Cy5 的良好替代品。

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  • BDP 650/665 maleimide

BDP 650/665 maleimide

标签：Maleimides, Near infrared (NIR) imaging, BDP 650/665
货号 规格 价格 货期
18480 1 mg 110.00$ in stock
28480 5 mg 210.00$ in stock
48480 25 mg 410.00$ in stock
58480 50 mg 695.00$ in stock
68480 100 mg 1190.00$ in stock

Maleimide is a thiol reactive group. The compound can be used for the labeling of cysteine residues of proteins and peptides, among other SH-containing molecules.

BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性，但可用于标记水环境中的生物分子，因此是 Cy5 的良好替代品。

马来酰亚胺是硫醇反应基团。 该化合物可用于标记蛋白质和肽以及其他含 SH 分子的半胱氨酸残基。

Absorption and emission spectra of BDP 650/665

BDP 650/665 maleimide

BDP 650/665 maleimide相关产品

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

BDP TR maleimide

BDP TR is a multi-purpose fluorophore with absorption and emission channels matching ROX dye. BDP TR is suitable for two photon, and fluorescence polarization studies.

BDP TR 是一种多用途荧光团，具有与 ROX 染料匹配的吸收和发射通道。 BDP TR 适用于两个光子和荧光偏振研究。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 555.2
Molecular weight: 555.34
Molecular formula: C29H24N5BF2O4
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

BDP 630/650 maleimide

BDP 630/650 maleimide,BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长，这种染料对于荧光寿命相关的测量特别有用。

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  • BDP 630/650 maleimide

BDP 630/650 maleimide

标签：Maleimides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15480 1 mg 110.00$ in stock
25480 5 mg 210.00$ in stock
45480 25 mg 410.00$ in stock
55480 50 mg 695.00$ in stock
65480 100 mg 1190.00$ in stock

BDP 630/650 is a far red emitting borondipyrromethene based fluorophore for the Cyanine5 channel. Because of its relatively long lifetime of the excited state, this dye is particularly useful for fluorescence lifetime related measurements.

The reactive maleimide moiety allows to attach the dye to thiol groups in biomolecules, especially proteins and peptides.

BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长，这种染料对于荧光寿命相关的测量特别有用。

反应性马来酰亚胺部分允许将染料连接到生物分子中的硫醇基团，尤其是蛋白质和肽。

Absorption and emission spectra of BDP 630/650

BDP 630/650 maleimide

BDP 630/650 maleimide相关产品

BDP 650/665 X NHS ester

Amine reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel, possessing a high molar extinction coefficient, and a good emission quantum yield.

BDP 650/665 的胺反应物，一种用于 Cy5 通道的硼二吡咯亚甲基染料，具有高摩尔消光系数和良好的发射量子产率。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cy5.5 染料衍生物。

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

用于肽和蛋白质的叠氮基标记的活化酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 572.2
Molecular weight: 572.39
CAS number: 2183473-31-4
Molecular formula: C29H23N4BF2O4S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 maleimide

BDP 581/591 maleimide,BDP 581/591 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质和肽的巯基。

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BDP 581/591 maleimide

标签：Maleimides, Fluorescence polarization, BDP 581/591
货号 规格 价格 货期
16480 1 mg 110.00$ in stock
26480 5 mg 210.00$ in stock
46480 25 mg 410.00$ in stock
56480 50 mg 695.00$ in stock
66480 100 mg 1190.00$ in stock
BDP 581/591 maleimide is a thiol reactive dye for the labeling of sulfhydryl groups of proteins and peptides.

The dye is useful for a variety of applications, such as microscopy, fluorescence polarization experiments, and even ROS detection (upon reaction with ROS, the dye changes its fluorescence).

BDP 581/591 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质和肽的巯基。

该染料可用于多种应用，例如显微镜检查、荧光偏振实验，甚至 ROS 检测（与 ROS 反应后，染料会改变其荧光）。

Absorption and emission spectra of BDP 581/591

BDP 581/591 maleimide

BDP 581/591 maleimide相关产品

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物，用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验，并可用作 ROS 探针。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 514.33
Molecular formula: C28H25N4BF2O3
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 maleimide

BDP 558/568 maleimide,BDP 558/568 是一种荧光团，最大荧光波长为 569 nm（在黄色光谱范围内）。 该染料具有低斯托克斯位移、高量子产率； 它是疏水的，对 pH 变化或溶剂极性相对不敏感。 根据其光谱特性，BDP 558/568 类似于 BODIPY™ 558/568 和 Cy3™ 等荧光团。 BDP 558/568 马来酰亚胺可用于与肽、蛋白质、抗体或其他含有游离硫醇基 (-SH) 的分子结合。

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  • BDP 558/568 maleimide

BDP 558/568 maleimide

标签：Maleimides, BDP 558/568
货号 规格 价格 货期
A7480 1 mg 110.00$ in stock
B7480 5 mg 210.00$ in stock
C7480 10 mg 310.00$ in stock
D7480 25 mg 410.00$ in stock
E7480 50 mg 695.00$ in stock
F7480 100 mg 1190.00$ in stock

BDP 558/568 is a fluorophore with a fluorescence maximum at 569 nm (in the yellow spectrum range). This dye has a low Stokes shift, high quantum yield; it is hydrophobic and relatively non-sensitive to pH changes or solvent polarity. By its spectral characteristics, BDP 558/568 is an analog of such fluorophores as BODIPY™ 558/568 and Cy3™. BDP 558/568 maleimide can be used for conjugation with peptides, proteins, antibodies, or other molecules that contain free thiol groups (-SH).

BDP 558/568 是一种荧光团，最大荧光波长为 569 nm（在黄色光谱范围内）。 该染料具有低斯托克斯位移、高量子产率； 它是疏水的，对 pH 变化或溶剂极性相对不敏感。 根据其光谱特性，BDP 558/568 类似于 BODIPY™ 558/568 和 Cy3™ 等荧光团。 BDP 558/568 马来酰亚胺可用于与肽、蛋白质、抗体或其他含有游离硫醇基 (-SH) 的分子结合。

Absorption and emission spectra of BDP 558/568

BDP 558/568 maleimide

BDP 558/568 maleimide相关产品

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

BDP 558/568 是光谱黄色区域的荧光团。 与其他 BDP 染料一样，这种荧光团具有高荧光量子产率、亮度和光稳定性。

BDP 558/568 amine

BDP 558/568 is a borondipyrromethene dye with yellow/orange emission. This amine derivative can be conjugated by means of reactions with various electrophiles.

BDP 558/568 是一种具有黄色/橙色发射光的硼二吡咯亚甲基染料。 这种胺衍生物可以通过与各种亲电子试剂的反应来缀合。

BDP 558/568 carboxylic acid

BDP 558/568 is a borondipyrromethene dye with yellow emission. The dye as a carboxylic acid can be used in peptide synthesis (after appropriate activation of the carboxylic group).

BDP 558/568 是一种具有黄色发射光的硼二吡咯亚甲基染料。 作为羧酸的染料可用于肽合成（在适当活化羧基后）。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 468.28
Molecular formula: C22H19N4BF2O3S
IUPAC name: 3-(5,5-difluoro-7-(thiophen-2-yl)-5H-5l4,6l4-dipyrrolo[1,2-c:2′,1′-f][1,3,2]diazaborinin-3-yl)-N-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)propanamide
Solubility: very soluble in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07
BODIPY™ is a trademark of Thermo Fisher Scientific. Cy™ is a trademark of Cytiva.

AF430 maleimide

AF430 maleimide,AF430 是香豆素性质的亲水染料。 该染料用于流式细胞术。这种马来酰亚胺衍生物对硫醇基团具有反应性。 因此，它可以标记许多蛋白质，包括那些驻留在细胞表面的蛋白质。

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  • AF430 maleimide

AF430 maleimide

标签：Maleimides, AF430
货号 规格 价格 货期
10880 1 mg 110.00$ in stock
20880 5 mg 290.00$ in stock
40880 25 mg 690.00$ in stock
50880 50 mg 1270.00$ in stock
60880 100 mg 1990.00$ in stock

AF430 is a hydrophilic dye of coumarin nature. The dye is used in flow cytometry.

This maleimide derivative is reactive against thiol groups. Therefore, it allows to label many proteins, including those residing on cell surface.

AF430 是香豆素性质的亲水染料。 该染料用于流式细胞术。

这种马来酰亚胺衍生物对硫醇基团具有反应性。 因此，它可以标记许多蛋白质，包括那些驻留在细胞表面的蛋白质。

Absorption and emission spectra of AF430

AF430 maleimide

AF430 maleimide相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

TAMRA NHS ester, 5-isomer

Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.

TAMRA 染料的胺反应活性 N-羟基琥珀酰亚胺酯，用于标记蛋白质、肽和氨基寡核苷酸的胺基。

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cyanine3 染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 625.2
Molecular weight: 726.8
Molecular formula: C34H45N4F3O8S
IUPAC name: (8-{6-[2-(2,5-Dioxo-1H-pyrrol-1-yl)ethylamino]-6-oxohexyl}-7,7-dimethyl-2-oxo-4-(trifluoromethyl)-1-oxa-8-aza-5,6,7,8-tetrahydroanthr-5-yl)methanesulfonic acid
Solubility: soluble in water, polar organic solvents (DMF, DMSO)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 430
ε, L⋅mol−1⋅cm−1: 15955
Emission maximum, nm: 542
Fluorescence quantum yield: 0.23
CF260: 0.06
CF280: 0.06