Cyanine5 alkyne,Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。
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- Cyanine5 alkyne
Cyanine5 alkyne
标签：Cyanine5,Cy5, Alkynes, Microscopy
| 货号 |
规格 |
价格 |
货期 |
| A30B0 |
1 mg |
110.00$ |
in stock |
| B30B0 |
5 mg |
210.00$ |
in stock |
| C30B0 |
10 mg |
310.00$ |
in stock |
| D30B0 |
25 mg |
410.00$ |
in stock |
| E30B0 |
50 mg |
695.00$ |
in stock |
| F30B0 |
100 mg |
1190.00$ |
in stock |
Cyanine5 alkyne for Click Chemistry, an analog of Cy5® alkyne. With this product, deeply colored, and photostable Cyanine5 fluorophore can be attached to various molecules via Click Chemistry reaction with azides.
This alkyne is non-water soluble, but it can be dissolved in DMF or DMSO prior to reaction, and added to aqueous reaction mixture. With our labeling protocol, the labeling reaction is very efficient, and high-yielding.
Various substrates bearing azides can be used for the labeling, including azido-labeled biomolecules, polymers, and solid surfaces.
Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。
这种炔烃不溶于水，但它可以在反应前溶解在 DMF 或 DMSO 中，然后加入到含水反应混合物中。 使用我们的标记方案，标记反应非常有效且产量高。
带有叠氮化物的各种基材可用于标记，包括叠氮标记的生物分子、聚合物和固体表面。
Cyanine5 absorbance and emission spectra
Cyanine5 alkyne
Sulfo-Cyanine3 alkyne
A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.
一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。
Pico488 dsDNA quantification reagent, 200x solution in DMSO
Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.
Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。
Ascorbic acid
Ascorbic acid for the reduction of Cu(II)-TBTA complex.
抗坏血酸用于还原 Cu(II)-TBTA 配合物。
General properties
| Appearance: |
dark blue powder 深蓝色粉末 |
| Molecular weight: |
556.18 |
| CAS number: |
1223357-57-0 |
| Molecular formula: |
C35H42ClN3O |
| Solubility: |
good in dichloromethane, DMF, DMSO, alcohols, very poorly soluble in water (200 mg/L = 0.4 mM) |
| Quality control: |
NMR 1H, HPLC-MS (95%) |
| Storage conditions: |
Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 |
| MSDS: |
Download |
|
Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: |
646 |
| ε, L⋅mol−1⋅cm−1: |
250000 |
| Emission maximum, nm: |
662 |
| Fluorescence quantum yield: |
0.2 |
| CF260: |
0.03 |
| CF280: |
0.04 |
相关文献：
- Liu, M.; Apriceno, A.; Sipin, M.; Scarpa, E.; Rodriguez-Arco, L.; Poma, A.; Marchello, G.; Battaglia, G.; Angioletti-Uberti, S. Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions. Nature Communications, 2020, 11, 4836. doi: 10.1038/s41467-020-18603-5
- Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
- Monteiro, P.F.; Gulfam, M.; Monteiro, C.J.; Travanut, A.; Abelha, T.F.; Pearce, A.K.; Jerôme, C.; Grabowska, A.M.; Clarke, P.A.; Collins, H.M.; Heery, D.M.; Gershkovich, P.; Alexander, C. Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. Journal of Controlled Release, 2020, 323, 549–564. doi: 10.1016/j.jconrel.2020.04.049
- Zivanovic, J.; Kouroussis, E.; Kohl, J.B.; Adhikari, B.; Bursac, B.; Schott-Roux, S.; Petrovic, D.; Miljkovic, J.L.; Thomas-Lopez, D.; Jung, Y.; Miler, M.; Mitchell, S.; Milosevic, V.; Gomes, J.E.; Benhar, M.; Gonzales-Zorn, B.; Ivanovic-Burmazovic, I.; Torregrossa, R:; Mitchell, J.R.; Whiteman, M.; Schwarz, G.; Snyder, S.H.; Paul, B.D.; Carroll, K.S.; Filipovic, M.R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 2019, 30(6), 1152–1170.e13. doi: 10.1016/j.cmet.2019.10.007
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