趋化因子Chemokines | Lumiprobe官网中国授权代理商

ProSpec-BCA-1 Human/CHM-348,BCA-1/BLC 人重组

BCA-1 Human
BCA-1/BLC Human Recombinant
CHM-348 5µg
CHM-348 20µg
CHM-348 1mg

Catalogue number

CHM-348

Synonyms

C-X-C motif chemokine 13, Small-inducible cytokine B13, B lymphocyte chemoattractant, CXC chemokine BLC, CXCL13, BCA1, BCA-1, CXCL-13, B cell Attracting Chemokine-1, BLC, ANGIE, BLR1L, SCYB13, ANGIE2.

Introduction

BCA-1 is a CXC chemokine that is highly expressed in thesecondary lymphoid organs, such as follicles of the spleen, lymph nodes, and Peyer’s patches. CXCL13 promotes the migration of B lymphocytes , by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt’s lymphoma receptor 1 . BCA1 therefore function in the homing of B lymphocytes to follicles. Human BCA-1 shares a 64% amino acid sequence similarity with the mouse protein and 23 – 34% amino acid sequence identity with other known CXC chemokines. Recombinant or chemically synthesized BCA1 is a potent chemoattractant for B lymphocytes but not T lymphocytes, monocytes or neutrophils. BLR1, a G protein-coupled receptor originally isolated from Burkitt’s lymphoma cells, has now been shown to be the specific receptor for BCA1. Among cells of the hematopoietic lineages, the expression of BLR-1, now designated CXCR-5, is restricted to B lymphocytes and a subpopulation of T helper memory cells.

BCA-1是一种CXC趋化因子，在次级淋巴器官中高度表达，例如脾脏、淋巴结和派尔氏斑的滤泡。 CXCL13 通过刺激钙流入并趋化表达伯基特淋巴瘤受体 1 的细胞，从而促进 B 淋巴细胞的迁移。因此，BCA1 在 B 淋巴细胞归巢到滤泡中起作用。人 BCA-1 与小鼠蛋白质具有 64% 的氨基酸序列相似性，与其他已知的 CXC 趋化因子具有 23-34% 的氨基酸序列同一性。重组或化学合成的 BCA1 对 B 淋巴细胞是一种有效的化学引诱物，但对 T 淋巴细胞、单核细胞或中性粒细胞没有。 BLR1 是一种 G 蛋白偶联受体，最初是从 Burkitt 淋巴瘤细胞中分离出来的，现在已被证明是 BCA1 的特异性受体。在造血谱系的细胞中，BLR-1（现在称为 CXCR-5）的表达仅限于 B 淋巴细胞和 T 辅助记忆细胞的一个亚群。

Description

在大肠杆菌中产生的 CXCL13 Human Recombinant 是一条单一的、非糖基化的多肽链，包含 87 个氨基酸，分子量为 10.3 kDa。
BCA-1 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The BCA-1 protein was lyophilized from a concentrated solution containing 20mM PBS & 150mM NaCl pH-7.4.

Solubility

It is recommended to reconstitute the lyophilized CXCL13 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized BCA1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BCA1 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNG CPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKR SSSTLPVPVFKRKIP.

Biological Activity

Determined by its ability to chemoattract human B cells using a concentration range of 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-BCA-1 Human, His/CHM-023,CHM-023 5µg

BCA-1 Human, His
BCA-1/ BLC Human Recombinant, His Tag

CHM-023 5µg
CHM-023 20µg
CHM-023 1mg

Catalogue number

CHM-023

Synonyms

Introduction

Description

BCA 1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain topological domain containing 110 amino acids and having a molecular mass of 12.7kDa. BCA 1 is fused to a 23 amino acid His-tag at N-terminus.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

BCA 1 protein solution containing 20mM Tris-HCl buffer , 0.4M Urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSVLEVYYT SLRCRCVQES SVFIPRRFID RIQILPRGNG CPRKEIIVWK KNKSIVCVDP QAEWIQRMME VLRKRSSSTL PVPVFKRKIP.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-BCA1 Macaque,BCA1猕猴/CHM-035

ProSpec-BCA1 Macaque,BCA1猕猴/CHM-035,BCA-1是一种CXC趋化因子，在次级淋巴器官中高度表达，例如脾脏、淋巴结和派尔氏斑的滤泡。 CXCL13 通过刺激钙流入并趋化表达伯基特淋巴瘤受体 1 的细胞，从而促进 B 淋巴细胞的迁移。

BCA1 Macaque
BCA-1/ BLC Rhesus Macaque Recombinant
CHM-035
CHM-035 50µg
CHM-035 100µg
CHM-035 1mg

Catalogue number

CHM-035

Synonyms

Introduction

Description

BCA-1/ BLC Rhesus Macaque Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 87 amino acid and having a molecular mass of approximately 10.3kDa.
BCA1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0 and 300mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized BCA-1/ BLC Rhesus Macaque in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized BCA1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BCA-1/ BLC Rhesus Macaque should be stored at 4°C between 2-7 days and for future use below -18°C.

Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VLEVYYTHLR CRCVQESSVF IPRRFIDRIQ ISPRGNGCPR KEIIVWKKNK SVVCVDPQAE WIQRIMEMLR KKSSSTPPVP VFKRKIP.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-BCA-1 Mouse/CHM-030,CHM-030,BCA-1/BLC Mouse Recombinant

BCA-1 Mouse
BCA-1/BLC Mouse Recombinant
CHM-030 5µg
CHM-030 20µg
CHM-030 1mg

Catalogue number

CHM-030

Synonyms

C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13, Blc, Scyb13.

Introduction

Description

CXCL13 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10kDa.
The BCA-1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The BCA1 protein was lyophilized from a 0.2µm filtered solution in Acetonitrile and TFA.

Solubility

It is recommended to reconstitute the lyophilized CXCL13 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by -PAGE.

Amino acid sequence

ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA.

Biological Activity

The ED₅₀, as measured by its ability to chemoattract human CXCR5-transfected mouse BaF3 cells, is less than 2µg/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-BRAK Human/CHM-001,BRAK人重组,CHM-001

Catalogue number

CHM-001

Synonyms

C-X-C motif chemokine 14, Small-inducible cytokine B14, Chemokine BRAK, Bolekine, NJAC, KS1, Kec, BMAC, MIP-2g, SCYB14, CXCL14, BRAK, MGC10687.

Introduction

CXCL14 is involved in immunoregulatory and inflammatory processes. BRAK protein is structurally related to the CXC subfamily of cytokines. CXCL14 displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. CXCL14 is involved in the homeostasis of monocyte-derived macrophages.

Description

CXCL14 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 77 amino acids and having a molecular mass of 9.4kDa.
The CXCL14 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL14 was lyophilized after extensive dialysis against 20mM Tris-HCl, pH 8.5 and 1M NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL14 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL14 should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Lys-Cys-Lys-Cys.

Biological Activity

The ED50 of CXCL14 as determined by its ability to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells was 1.0-10.0 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec CHM-239,BRAK Human, His,BRAK人重组体,CHM-239

ProSpec CHM-239,BRAK Human, His,BRAK人重组体,CHM-239,在大肠杆菌中产生的 CXCL14 Human Recombinant 是一种单一的、非糖基化的多肽链，包含 88 个氨基酸，分子量为 10.66 kDa。

BRAK Human, His

BRAK Human Recombinant , His-Tag

CHM-239

1µg

5µg

50µg

Catalogue number

CHM-239

Synonyms

C-X-C motif chemokine 14, Small-inducible cytokine B14, Chemokine BRAK, Bolekine, NJAC, KS1, Kec, BMAC, MIP-2g, SCYB14, CXCL14, BRAK, MGC10687.

Introduction

CXCL14 参与免疫调节和炎症过程。 BRAK 蛋白在结构上与细胞因子的 CXC 亚家族相关。 CXCL14 对单核细胞显示趋化活性，但对淋巴细胞、树突细胞、中性粒细胞或巨噬细胞没有趋化活性。 CXCL14 参与单核细胞衍生巨噬细胞的稳态。

Description

CXCL14 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10.66 kDa.
The Human BRAK contains a 10 a.a. fusion His tag at N-Terminus.
The BRAK is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 CXCL14 Human Recombinant 是一种单一的、非糖基化的多肽链，包含 88 个氨基酸，分子量为 10.66 kDa。
Human BRAK 包含一个 10 a.a. 在 N 末端融合 His 标签。
BRAK 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Filtered White lyophilized powder.

Formulation

CXCL14 filtered and lyophilized from a concentrated solution containing 20mM Tris buffer & 20mM NaCl pH-7.5.

Solubility

建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶冻干的 CXCL14，然后可以进一步稀释成其他水溶液。产品不是无菌的！在细胞培养中使用之前，请用适当的无菌过滤器过滤产品。

Stability

Lyophilized BRAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BRAK should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 BRAK 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重构后，BRAK 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

MKHHHHHHAS SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec CHM-007,BRAK Mouse,BRAK 小鼠重组,CHM-007

BRAK Mouse
BRAK Mouse Recombinant
CHM-007
5µg

20µg

1mg

Catalogue number

CHM-007

Synonyms

C-X-C motif chemokine 14, B-cell and monocyte-activating chemokine, Chemokine BRAK, Kidney-expressed chemokine CXC, MIP-2G, Small-inducible cytokine B14, Cxcl14, Bmac, Kec, Ks1, Mip2g, Scyb14, BRAK, NJAC, AI414372, bolekine, MIP2gamma, 1110031L23Rik, 1200006I23Rik.

Introduction

Description

在大肠杆菌中产生的 CXCL14 Mouse Recombinant 是一种单一的、非糖基化的多肽链，含有 77 个氨基酸，分子量为 9.4kDa。
CXCL14 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL14 was lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4 and 500mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE.

Biological Activity

The ED₅₀ of CXCL14 as determined by its ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec CHM-021,BRAK Rat,BRAK 大鼠重组/CHM-021

ProSpec CHM-021,BRAK Rat,BRAK 大鼠重组/CHM-021,CXCL14 参与免疫调节和炎症过程。 BRAK 蛋白在结构上与细胞因子的 CXC 亚家族相关。 CXCL14 对单核细胞显示趋化活性，但对淋巴细胞、树突细胞、中性粒细胞或巨噬细胞没有趋化活性。 CXCL14 参与单核细胞衍生巨噬细胞的稳态。

BRAK Rat
BRAK Rat Recombinant
CHM-021
5µg

20µg

1mg

Catalogue number

CHM-021

Synonyms

Introduction

Description

CXCL14 Rat Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 77 amino acids and having a molecular mass of 9.4kDa.
The CXCL14 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL14 was lyophilized from a 0.2µm filtered concentrated solution in 30% Acetonitrile and 0.1% TFA.

Solubility

It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE.

Biological Activity

Determined by its ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-C-10 Mouse/CHM-307,C-10 小鼠重组/CHM-307

ProSpec-C-10 Mouse/CHM-307,C-10 小鼠重组/CHM-307,CCL6 也可以在小鼠肺中由细胞因子白介素 13 诱导。小鼠 CCL6 位于 11 号染色体上。CCL6 的细胞表面受体被认为是趋化因子受体 CCR1。

C-10 Mouse
C-10 Mouse Recombinant
CHM-307
2µg

10µg

1mg

Catalogue number

CHM-307

Synonyms

Small inducible cytokine A6, CCL6, C10 protein, c10, MRP-1, Scya6, chemokine ligand 6.

Introduction

Chemokine ligand 6 is a small cytokine belonging to the CC chemokine family that has only been identified in rodents.
In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced. CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

趋化因子配体 6 是一种小细胞因子，属于 CC 趋化因子家族，仅在啮齿动物中发现。
在小鼠中，CCL6 在来自嗜中性粒细胞和巨噬细胞谱系的细胞中表达，并且可以在适合骨髓细胞分化的条件下被大量诱导。它在用细胞因子 GM-CSF 刺激的骨髓培养物中高度表达。某些低水平的基因表达也出现在某些骨髓来源的细胞系中，这些细胞系也可以在 GM-CSF 培养中被大大诱导。然而，在活化的 T 细胞系中，CCL6 的表达大大降低。 CCL6 也可以在小鼠肺中由细胞因子白介素 13 诱导。小鼠 CCL6 位于 11 号染色体上。CCL6 的细胞表面受体被认为是趋化因子受体 CCR1。

Description

C-10 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 95 amino acids and having a molecular mass of 10.7kDa.
The CCL6 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CCL6 Mouse was lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized C10 protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized C10 protein although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL6 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA.

Biological Activity

The Biological activity was determined by its ability to chemoattract human CCR1 transfected BaF3 mouse proB cells using a concentration range of 0.05-0.25µg/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-C-10 Rat/CHM-268,C-10 大鼠重组/CHM-268

ProSpec-C-10 Rat/CHM-268,C-10 大鼠重组/CHM-268,Lyophilized C-10 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution C-10 should be stored at 4C between 2-7 days and for future use below -18C.

C-10 Rat
C-10 Rat Recombinant
CHM-268
2µg

10µg

1mg

Catalogue number

CHM-268

Synonyms

Small inducible cytokine A6, CCL6, C10 protein, c10, MRP-1, Scya6, chemokine ligand 6.

Introduction

Description

C-10 Rat Recombinant produced in E.Coli is a signle, non-glycosylated, polypeptide chain containing 94 amino acids and having a total molecular mass of 10.4kDa.
C-10 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized C-10 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized C-10 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution C-10 should be stored at 4C between 2-7 days and for future use below -18C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

GLIQDTVKED RPFNPTIIHQ GFQDSSDCCF SYASQIPCSR FIYYFPTSGG CTKPGIIFVT RKRKRVCANP SDQRVQTCIS TLKLGPRSGN SAIA.

Biological Activity

Determined by its ability to chemoattract human CCR1 transfected BaF3 mouse proB cells using a concentration range of 0.05-0.25 ug/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CTACK Human/CHM-373,CTACK 人重组/CHM-373

ProSpec-CTACK Human/CHM-373,CTACK 人重组/CHM-373,ALP, CTACK, ESKINE, ILC, PESKY, SCYA27, CCL27, C-C motif chemokine 27, Small-inducible cytokine A27, IL-11 R-alpha-locus chemokine, Skinkine, ESkine, Cutaneous T-cell-attracting chemokine.

CTACK Human
CTACK Human Recombinant
CHM-373
5µg

20µg

1mg

Catalogue number

CHM-373

Synonyms

ALP, CTACK, ESKINE, ILC, PESKY, SCYA27, CCL27, C-C motif chemokine 27, Small-inducible cytokine A27, IL-11 R-alpha-locus chemokine, Skinkine, ESkine, Cutaneous T-cell-attracting chemokine.

Introduction

CTACK is a chemotactic factor that attracts skin-associated memory T-lymphocytes. CTACK is involved in mediating homing of lymphocytes to cutaneous sites. CTACK Binds to CCR10.

Description

在大肠杆菌中产生的 CTACK Human Recombinant 是一种单一的、非糖基化的多肽链，包含 89 个氨基酸，分子量为 10.3kDa。 CTACK 蛋白通过标准色谱法纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CTACK Human solution containing 10mM sodium citrate pH-3.5 & 10% glycerol.

Stability

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Amino acid sequence

MFLLPPSTAC CTQLYRKPLS DKLLRKVIQV ELQEADGDCH LQAFVLHLAQ RSICIHPQNP SLSQWFEHQE RKLHGTLPKL NFGMLRKMG.

Purity

Greater than 95% as determined by -PAGE.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CTACK Mouse/CHM-013,CTACK 小鼠重组/CHM-013

ProSpec-CTACK Mouse/CHM-013,CTACK 小鼠重组/CHM-013,CTACK 是一种趋化因子，可吸引与皮肤相关的记忆 T 淋巴细胞。 CTACK 参与介导淋巴细胞向皮肤部位的归巢。 CTACK 与 CCR10 结合。

CTACK Mouse
CTACK Mouse Recombinant
CHM-013
5µg

20µg

1mg

Catalogue number

CHM-013

Synonyms

C-C motif chemokine 27, CC chemokine ILC, Cutaneous T-cell-attracting chemokine, CTACK, ESkine, IL-11 R-alpha-locus chemokine, ALP, mILC, Skinkine, Small-inducible cytokine A27, Ccl27, Ilc, Scya27.

Introduction

CTACK 是一种趋化因子，可吸引与皮肤相关的记忆 T 淋巴细胞。 CTACK 参与介导淋巴细胞向皮肤部位的归巢。 CTACK 与 CCR10 结合。

Description

CTACK Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 95 amino acids and having a molecular mass of 10.9kDa.
The CTACK is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH7.4 and 300mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CTACK in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 CTACK 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。复溶后，CTACK 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN.

Biological Activity

The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CXCL16 Human/CHM-029,CXCL16 人重组/CHM-029

CXC 趋化因子配体 16 是一种 I 型膜蛋白，在其细胞外区域包含一个不含 ELR 基序的 CXC 趋化因子结构域。人和小鼠 CXCL16 共享 70% a.a. 其趋化因子结构域内的序列相似性和 49% 的总体 a.a. 序列同一性。

CXCL16 Human
CXCL16 Human Recombinant
CHM-029
5µg

25µg

1mg

Catalogue number

CHM-029

Synonyms

Chemokine Ligand 16, Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein, Transmembrane Chemokine CXCL16, Small-Inducible Cytokine B16, CXC Chemokine Ligand 16, SR-PSOX, SRPSOX, C-X-C Motif Chemokine 16, CXCLG16, SCYB16, CXCL16.

Introduction

CXC 趋化因子配体 16 是一种 I 型膜蛋白，在其细胞外区域包含一个不含 ELR 基序的 CXC 趋化因子结构域。人和小鼠 CXCL16 共享 70% a.a. 其趋化因子结构域内的序列相似性和 49% 的总体 a.a. 序列同一性。功能性 CXCL16 可以作为大约 35kDa 可溶性蛋白从细胞表面脱落。 CXCR6 是 CXCL16 的功能性受体。 CXCL16 充当巨噬细胞上的清道夫受体，与 OxLDL 特异性结合，提示 CXCL16 可能参与动脉粥样硬化等病理生理学。此外，CXCL16 诱导强烈的趋化反应和钙动员。 CXCL16 与 CXCR6/Bonzo 结合。

Description

CXCL16 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 89 amino acids and having a molecular mass of 10kDa.
The CXCL16 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL16 protein was lyophilized from a 0.2µm filtered solution in PBS.

Solubility

It is recommended to reconstitute the lyophilized CXCL16 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 CXCL16 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重构后，CXCL16 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by -PAGE.

Amino acid sequence

NEGSVTGSCY CGKRISP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP.

Biological Activity

The ED₅₀, as measured by its ability to chemoattract mouse CXCR6-transfected mouse BaF3 cells, is less than 12ng/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CXCL16 Mouse/CHM-363,CXCL16 小鼠重组/CHM-363

ProSpec-CXCL16 Mouse/CHM-363,CXCL16 小鼠重组/CHM-363,在大肠杆菌中产生的 CXCL16 Mouse Recombinant 是一条单一的、非糖基化的多肽链，包含 88 个氨基酸，分子量为 9.9kDa。

CXCL16 Mouse
CXCL16 Mouse Recombinant
CHM-363
5µg

25µg

1mg

Catalogue number

CHM-363

Synonyms

C-X-C motif chemokine 16, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, SR-PSOX, Cxcl16, Srpsox, Zmynd15, AV290116, BB024863, 0910001K24Rik.

Introduction

小鼠 CXCL16 是一种非 ELR 基序，包括具有跨膜结构域的 CXC 趋化因子。小鼠 CXCL16 cDNA 编码一个 246 a.a.具有假定 26 a.a. 的前体蛋白。残基信号肽，一个 88 a.a.残留趋化因子结构域，一个 87 a.a.残留粘蛋白样间隔区，a 22 a.a.残基跨膜结构域和一个 23 a.a.残基胞质尾。
CXCL16 诱导强烈的趋化反应和钙动员。此外，CXCL16 可作为巨噬细胞上的清道夫受体，与 OxLDL 特异性结合，这表明它可能与动脉粥样硬化等病理生理学有关。
小鼠 CXCL16 由淋巴器官 T 细胞区域中的树突状细胞以及脾红髓中的细胞以膜结合和可溶形式产生。 CXCR6/Bonzo 是 CXCL16 的受体。 CXCL16 在脾脏、淋巴结和 Peyer 斑块中表达。它还在肺、肾、小肠和胸腺等非淋巴组织中表达，在心脏和肝脏中表达较弱，在脑和纯化的 B 细胞和 T 细胞中不表达。
CXCL16 缺乏与乳腺癌进展有关。此外，CXCL16 通过调节肝组织中 T 淋巴细胞浸润参与免疫性肝损伤。此外，CXCL16 在维持由自然杀伤 T 细胞介导的心脏同种异体移植物耐受性方面具有独特的作用。此外，CXCL16 不仅在 NKT 细胞产生 IFN-γ 方面具有重要作用，而且在促进由 NKT 细胞介导的 Th1 倾向的免疫反应中也具有重要作用。

Description

在大肠杆菌中产生的 CXCL16 Mouse Recombinant 是一条单一的、非糖基化的多肽链，包含 88 个氨基酸，分子量为 9.9kDa。
CXCL16 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The protein was lyophilized from a concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL16 Mouse in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL16 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL16 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP.

Biological Activity

Determined by its ability to chemoattract murine lymphocytes using a concentration range of 100-1000ng/ml corresponding to a Specific Activity of 1,000-10,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CXCL17 Human/CHM-019,VEGF 共调节趋化因子 1 人重组/CHM-019

ProSpec-CXCL17 Human/CHM-019,VEGF 共调节趋化因子 1 人重组/CHM-019,树突状细胞和单核细胞趋化因子样蛋白是一种分泌型分子，其大小和预测的 3 维折叠模式类似于趋化因子 CXCL8/IL8 和 CXCL14/BRAK。 CXCL17 由气道和肠上皮组成性地产生。

CXCL17 Human
VEGF Co-regulated Chemokine 1 Human Recombinant
CHM-019
5µg

25µg

1mg

Catalogue number

CHM-019

Synonyms

VEGF coregulated chemokine 1, C-X-C motif chemokine 17, Dendritic cell and monocyte chemokine-like protein, DMC, CXCL17, VCC1, Dcip1, VCC-1, UNQ473.

Introduction

树突状细胞和单核细胞趋化因子样蛋白是一种分泌型分子，其大小和预测的 3 维折叠模式类似于趋化因子 CXCL8/IL8 和 CXCL14/BRAK。 CXCL17 由气道和肠上皮组成性地产生。 CXCL17 诱导静止的、但不是 LPS 激活的外周血单核细胞和树突状细胞的趋化性，并且它还特异性地结合这些细胞。当体外诱导形成管时，内皮细胞中CXCL17的表达增加。在血管生成中起作用的CXCL17、CXCL1/GRO和CXCL8/IL8在原发性肺、乳腺和食管肿瘤中与VEGF的表达显着相关。因此，CXCL17被认为在肿瘤血管生成中起作用。成熟的大鼠 CXCL17 分别与小鼠、人 CXCL17 共享 82%、71% 的氨基酸序列同一性。

Description

CXCL17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 98 amino acids and having a molecular mass of 11.5kDa.
The CXCL17 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL17 protein was lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4, containing 3% Trehalose.

Solubility

It is recommended to reconstitute the lyophilized CXCL17 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 CXCL17 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重组后，CXCL17 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL.

Biological Activity

The ED₅₀as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0µg/ml, corresponding to a specific activity of > 200IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CXCL17 Human, His/CHM-024

ProSpec-CXCL17 Human, His/CHM-024,树突状细胞和单核细胞趋化因子样蛋白是一种分泌型分子，其大小和预测的 3 维折叠模式类似于趋化因子 CXCL8/IL8 和 CXCL14/BRAK。 CXCL17 由气道和肠上皮组成性地产生。

CXCL17 Human, His
VEGF Co-regulated Chemokine 1, His Tag Human Recombinant
VEGF 共调节趋化因子 1，His 标签人重组
CHM-024
2µg

10µg

1mg

Catalogue number

CHM-024

Synonyms

Dcip1, DMC, MGC138300, UNQ473, VCC-1, VCC1, VEGF coregulated chemokine 1, C-X-C motif chemokine 17, Dendritic cell and monocyte chemokine-like protein.

Introduction

Description

CXCL17 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 119 amino acids and having a molecular mass of 13.7kDa.CXCL17 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

CXCL17 protein solution contains 20mM Tris-HCl buffer , 0.4M Urea and 10% glycerol.

Stability

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-CXCL17 Rat/CHM-281,VEGF 共调节趋化因子 1 大鼠重组/CHM-281

ProSpec-CXCL17 Rat/CHM-281,VEGF 共调节趋化因子 1 大鼠重组/CHM-281,树突状细胞和单核细胞趋化因子样蛋白是一种分泌型分子，其大小和预测的 3 维折叠模式类似于趋化因子 CXCL8/IL8 和 CXCL14/BRAK。 CXCL17 由气道和肠上皮组成性地产生。

CXCL17 Rat
VEGF Co-regulated Chemokine 1 Rat Recombinant
CHM-281
5µg

25µg

1mg

Catalogue number

CHM-281

Synonyms

Protein Cxcl17, Cxcl17, RGD1304717, C-X-C motif chemokine 17, VEGF co-regulated chemokine 1, Vcc1, VCC-1.

Introduction

Description

CXCL17 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 97 amino acids and having a molecular mass of 11.5kDa.
The CXCL17 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL17 protein was lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, 300mM NaCl, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized CXCL17 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL17 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL17 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SPNQEVARHH GDQHQAPRRW LWEGGQECDC KDWSLRVSKR KTTAVLEPPR KQCPCDHVKG SEKKNRRQKH HRKSQRPSRT CQQFLKRCQL ASFTLPL.

Biological Activity

Measured by its ability to induce VEGF expression in mouse endothelial cells. The ED₅₀ for this effect is typically 1-5 µg/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GCP2 Bovine/CHM-040,粒细胞趋化蛋白2牛重组/CHM-040

ProSpec-GCP2 Bovine/CHM-040,粒细胞趋化蛋白2牛重组/CHM-040,粒细胞趋化蛋白 2，也称为 GCP-2，是一种中性粒细胞趋化蛋白。 GCP-2 通过其受体的结合和激活发出信号。

GCP2 Bovine
Granulocyte Chemotactic Protein 2 Bovine Recombinant
CHM-040
50µg

100µg

1mg

Catalogue number

CHM-040

Synonyms

C-X-C motif chemokine 6, Chemokine alpha 3, CKA-3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6.

Introduction

粒细胞趋化蛋白 2，也称为 GCP-2，是一种中性粒细胞趋化蛋白。 GCP-2 通过其受体的结合和激活发出信号。 GCP-2除了具有趋化性和血管生成特性外，对革兰氏阳性菌和革兰氏阴性菌具有很强的抗菌活性。

Description

在大肠杆菌中产生的粒细胞趋化蛋白 2 牛重组体是一种非糖基化多肽链，含有 76 个氨基酸，分子量约为 8.0kDa。
GCP2 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB and 500mM NaCl, pH 7.0.

Solubility

It is recommended to reconstitute the lyophilized Granulocyte Chemotactic Protein 2 in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 GCP2 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重构后，粒细胞趋化蛋白 2 应在 4°C 下储存 2-7 天，以备将来在低于 -18°C 的温度下使用。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

GPVAAVVREL RCVCLTTTPG IHPKTVSDLQ VIAAGPQCSK VEVIATLKNG REVCLDPEAP LIKKIVQKIL DSGKNN.

Biological Activity

The biological activity determined by a chemotaxis bioassay using human neutrophils is 10-50 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GCP-2 Human/CHM-025,粒细胞趋化蛋白2人重组/CHM-025

ProSpec-GCP-2 Human/CHM-025,粒细胞趋化蛋白2人重组/CHM-025,粒细胞趋化蛋白 2，也称为 GCP-2，是一种中性粒细胞趋化蛋白。

GCP-2 Human
Granulocyte Chemotactic Protein 2 Human Recombinant
CHM-025
5µg

20µg

1mg

Catalogue number

CHM-025

Synonyms

C-X-C motif chemokine 6, Chemokine alpha 3, CKA-3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6.

Introduction

粒细胞趋化蛋白 2，也称为 GCP-2，是一种中性粒细胞趋化蛋白。 GCP-2 通过其受体的结合和激活发出信号。 GCP-2 除了具有趋化性和血管生成特性外，对革兰氏阳性菌和革兰氏阴性菌具有很强的抗菌活性。

Description

GCP-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 72 amino acids and having a molecular mass of 7.9kDa.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

GCP-2 protein was lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized GCP-2 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 GCP-2 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。复溶后，GCP-2 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 10-50 ng/ml corresponding to a specific activity of 20,000-100,000 IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-ENA 78 Human/CHM-331,上皮中性粒细胞激活蛋白 78 人重组/CHM-331

ENA 78 Human

Catalogue number

CHM-331

Synonyms

Small inducible cytokine B5, CXCL5, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, ENA-78, chemokine ligand 5, SCYB5.

Introduction

趋化因子配体 5 是一种小细胞因子，属于 CXC 趋化因子家族，也称为上皮衍生的中性粒细胞激活肽 78。它是在用炎性细胞因子 IL-1 或肿瘤坏死因子-α 刺激细胞后产生的。在嗜酸性粒细胞中也观察到了 CXCL5 的表达，并且可以被 II 型 IFN 抑制。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。它通过与细胞表面趋化因子受体 CXCR2 相互作用引发这些效应。 CXCL5 基因在四个外显子上编码，位于人类第 4 号染色体上，与其他几个 CXC 趋化因子基因一起。 CXCL5 与结缔组织重塑有关。

Description

在大肠杆菌中产生的上皮中性粒细胞激活蛋白 78 人重组体是一种单一的、非糖基化的多肽链，含有 74 个氨基酸，分子量为 8020 道尔顿。
CXCL5 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The CXCL5 was lyophilized from a concentrated solution in water containing no additives.

Solubility

It is recommended to reconstitute the lyophilized ENA-78 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized ENA78 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be, Ala- Ala -Val-Leu-Arg.

Biological Activity

The biological activity was determined by measuring the dose dependent mobilization of intracellular calcium with human neutrophils. Significant calcium mobilization is observed with 100ng/mL of recombinant human ENA-78.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec CHM-265,ENA 78 Human (8-78 a.a.),上皮中性粒细胞激活蛋白 78, 8-78 a.a. 人类重组

ProSpec CHM-265,ENA 78 Human (8-78 a.a.),上皮中性粒细胞激活蛋白 78, 8-78 a.a. 人类重组,在嗜酸性粒细胞中也观察到了 CXCL5 的表达，并且可以被 II 型干扰素 IFN-α 抑制。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。

ENA 78 Human
Epithelial Neutrophil-Activating Protein 78, 8-78 a.a. Human Recombinant
CHM-265
5µg

20µg

1mg

Catalogue number

CHM-265

Synonyms

Small inducible cytokine B5, CXCL5, Epithelial-derived neutrophil-activating protein 78, Neutrophil-activating peptide ENA-78, ENA-78, chemokine ligand 5, SCYB5.

Introduction

趋化因子配体 5 是一种小细胞因子，属于 CXC 趋化因子家族，也称为上皮衍生的中性粒细胞激活肽 78。它是在用炎性细胞因子 IL-1 或肿瘤坏死因子-α 刺激细胞后产生的。在嗜酸性粒细胞中也观察到了 CXCL5 的表达，并且可以被 II 型干扰素 IFN-α 抑制。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。它通过与细胞表面趋化因子受体 CXCR2 相互作用引发这些效应。 CXCL5 基因在四个外显子上编码，位于人类第 4 号染色体上，与其他几个 CXC 趋化因子基因一起。 CXCL5 与结缔组织重塑有关。

Description

在大肠杆菌中产生的上皮中性粒细胞激活蛋白 78 人重组体是一种单一的、非糖基化的多肽链，包含 71 个氨基酸，分子量为 7.8kDa。 CXCL5 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 1xPBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized ENA-78 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N.

Biological Activity

The biological activity was determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec CHM-365,ENA 78 Mouse,上皮中性粒细胞激活蛋白 78 小鼠重组

ProSpec CHM-365,ENA 78 Mouse,上皮中性粒细胞激活蛋白 78 小鼠重组,冻干的 ENA-78 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。复溶后，CXCL5 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。

ENA 78 Mouse
Epithelial Neutrophil-Activating Protein 78 Mouse Recombinant
CHM-365
5µg

20µg

1mg

Catalogue number

CHM-365

Synonyms

C-X-C motif chemokine 5, Small-inducible cytokine B5, Cytokine LIX, Cxcl5, Scyb5, LIX, GCP-2, Scyb6, ENA-78, AMCF-II.

Introduction

趋化因子配体 5 是一种小细胞因子，属于 CXC 趋化因子家族，也称为上皮衍生的中性粒细胞激活肽 78。它是在用炎性细胞因子 IL-1 或肿瘤坏死因子-α 刺激细胞后产生的。在嗜酸性粒细胞中也观察到了 CXCL5 的表达。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。它通过与细胞表面趋化因子受体 CXCR2 相互作用引发这些效应。 CXCL5 基因在四个外显子上编码，位于人类第 4 号染色体上，与其他几个 CXC 趋化因子基因一起。 CXCL5 与结缔组织重塑有关。

Description

在大肠杆菌中产生的上皮中性粒细胞激活蛋白 78 小鼠重组体是一条含有 93 个氨基酸且分子量为 9.8kDa 的单一非糖基化多肽链。
CXCL5 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM sodium phosphate buffer, pH 7.4 & 150mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized ENA-78 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 ENA-78 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。复溶后，CXCL5 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ.

Biological Activity

Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec ENA 78 Rat,ENA 78 Rat,上皮中性粒细胞激活蛋白 78 大鼠重组

ProSpec ENA 78 Rat,ENA 78 Rat,上皮中性粒细胞激活蛋白 78 大鼠重组,在嗜酸性粒细胞中也观察到了 CXCL5 的表达。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。它通过与细胞表面趋化因子受体 CXCR2 相互作用引发这些效应。

ENA 78 Rat
Epithelial Neutrophil-Activating Protein 78 Rat Recombinant
CHM-267
5µg

20µg

1mg

Catalogue number

CHM-267

Synonyms

C-X-C motif chemokine 5, Small-inducible cytokine B5, Cytokine LIX, Cxcl5, Scyb5, LIX, GCP-2, Scyb6, ENA-78, AMCF-II.

Introduction

Description

Epithelial Neutrophil-Activating Protein 78 Rat Recombinant produced in E.Coli is a single,
non-glycosylated, polypeptide chain containing 93 amino acids and having a molecular mass of 10.0kDa.
The CXCL5 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized ENA-78 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized ENA-78 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

APFSAMVATE LRCVCLTLAP RINPKMIANL EVIPAGPHCP KVEVIAKLKN QKDNVCLDPQ APLIKKVIQK ILGSENKKTK RNALALVRSA STQ.

Biological Activity

Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-LIX Mouse CHM-031,LIX 小鼠重组 CHM-031

ProSpec-LIX Mouse CHM-031,LIX 小鼠重组 CHM-031,在嗜酸性粒细胞中也观察到了 CXCL5 的表达，并且可以被 II 型 IFN 抑制。这种趋化因子刺激嗜中性粒细胞的趋化性，具有血管生成特性。它通过与细胞表面趋化因子受体 CXCR2 相互作用引发这些效应。

LIX Mouse
LIX Mouse Recombinant
CHM-031
5µg

20µg

1mg

Catalogue number

CHM-031

Synonyms

C-X-C motif chemokine 5, Small-inducible cytokine B5, Cytokine LIX, Cxcl5, Scyb5, LIX, GCP-2, Scyb6, ENA-78, AMCF-II.

Introduction

Description

LIX Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 74 amino acids and having a molecular mass of 8kDa.
The LIX Mouse is expressed with 4 additional amino acids [VIAA] at n-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

LIX Mouse is lyophilized from a 0.2µm filtered solution in PBS.

Solubility

It is recommended to reconstitute the lyophilized LIX Mouse in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized LIX Mouse although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by -PAGE.

Amino acid sequence

VIAATELRCV CLTVTPKINP KLIANLEVIP AGPQCPTVEV IAKLKNQKEV CLDPEAPVIK KIIQKILGSD KKKA.

Biological Activity

The ED₅₀, as measured by its ability to chemoattract human CXCR2-transfected mouse BaF3 cells, is less than 0.1µg/ml.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin 2 Human CHM-238,Eotaxin-2 人重组体

ProSpec-Eotaxin 2 Human CHM-238,Eotaxin-2 人重组体,Eotaxin-2，也称为 MPIF2 和 Ckb6，是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。

Eotaxin 2 Human
Eotaxin-2 Human Recombinant
CHM-238
5µg

20µg

1mg

Catalogue number

CHM-238

Synonyms

C-C motif chemokine 24, Small-inducible cytokine A24, Myeloid progenitor inhibitory factor 2, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, CCL24, Ckb-6, MPIF2, MPIF-2, SCYA24, Eotaxin2, CCL-24.

Introduction

Eotaxin-2，也称为 MPIF2 和 Ckb6，是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。 Eotaxin-2 选择性地趋化表达 CCR3 的细胞，包括嗜酸性粒细胞、嗜碱性粒细胞、Th2 T 细胞、肥大细胞和某些树突状细胞亚群。此外，Eotaxin-2 抑制多能造血祖细胞的增殖。包含 C 末端截短的成熟蛋白质包含 78 个氨基酸。
CCL24 用作静息 t 淋巴细胞和嗜酸性粒细胞的趋化因子。 CCL24 对中性粒细胞具有较低的趋化活性，但对单核细胞和活化的淋巴细胞则没有。 CCL24 是多能造血祖细胞系形成集落的强抑制因子，并与 CCR3 结合。

Description

CCL24 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 8.8 kDa.
The CCL24 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The CCL24 protein was lyophilized from a concentrated sterile solution containing 20mM PBS pH-7.4 and 0.15M sodium chloride.

Solubility

It is recommended to reconstitute the lyophilized CCL24 Human Recombinant in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Eotaxin-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL24 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKGGVIFTTKKGQQFCG
DPKQEWV QRYMKNLDAKQKKASPRARAVA.

Biological Activity

The activity is determined by the chemoattract of human PBE at a concentration between 50-100 ng/ml corresponding to a Specific Activity of 10,000-20,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin 2 Mouse,Eotaxin-2 小鼠重组CHM-368

Eotaxin-2，也称为 MPIF2 和 Ckb6，是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。ProSpec-Eotaxin 2 Mouse,Eotaxin-2 小鼠重组CHM-368

Eotaxin 2 Mouse
Eotaxin-2 Mouse Recombinant
CHM-368
5µg

20µg

1mg

Catalogue number

CHM-368

Synonyms

Introduction

Description

CCL24 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.3 kDa.
The CCL24 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The CCL24 protein was lyophilized from a concentrated sterile solution containing 20mM Phosphate buffer pH-7.4 and 0.15M sodium chloride.

Solubility

It is recommended to reconstitute the lyophilized CCL24 Mouse Recombinant in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by: Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV.

Biological Activity

Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin 2 Rat,Eotaxin-2 大鼠重组 CHM-282

ProSpec-Eotaxin 2 Rat,Eotaxin-2 大鼠重组 CHM-282,Eotaxin-2，也称为 MPIF2 和 Ckb6，是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。

Eotaxin 2 Rat
Eotaxin-2 Rat Recombinant
CHM-282
5µg

20µg

1mg

Catalogue number

CHM-282

Synonyms

Introduction

Description

CCL24 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.2kDa.
The CCL24 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized CCL24 Rat Recombinant in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

VTIPSSCCVT FISKKIPVNR VISYQLANGS ICPKAGVIFI TKKGHKICTD PKLPWVQKHI KNLDAKRNQP SEGAKALGPK FVIQKLRGNS TKV.

Biological Activity

Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin 3 Human,Eotaxin-3 人重组体 CHM-362

Eotaxin-3 是一种小细胞因子，属于 CC 趋化因子家族，也称为 TARC。 CCL26 是由肺泡上皮细胞产生和释放的主要趋化因子，参与 CCR3 受体和其他趋化因子的自动调节。ProSpec-Eotaxin 3 Human,Eotaxin-3 人重组体 CHM-362

Eotaxin 3 Human
Eotaxin-3 Human Recombinant
CHM-362
10µg

50µg

1mg

Catalogue number

CHM-362

Synonyms

C-C motif chemokine 26, Small-inducible cytokine A26, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, Thymic stroma chemokine-1, TSC-1, CC chemokine IMAC, CCL26, SCYA26, IMAC, MIP-4a, MGC126714, MIP-4alpha.

Introduction

Eotaxin-3 是一种小细胞因子，属于 CC 趋化因子家族，也称为 TARC。 CCL26 是由肺泡上皮细胞产生和释放的主要趋化因子，参与 CCR3 受体和其他趋化因子的自动调节。 Eotaxin-3 参与免疫调节和炎症过程。 Eotaxin-3 特异性结合并刺激 T 细胞中的趋化性，并通过与趋化因子受体 CCR4 相互作用引发其作用。 CCL26 对正常外周血嗜酸性粒细胞和嗜碱性粒细胞表现出趋化活性。 Eotaxin-3 可能在特应性疾病中的嗜酸性粒细胞积累中发挥作用。 Eotaxin-3 在嗜酸性食管炎中过度表达，表达水平与疾病严重程度相关。 Eotaxin-3 在胸腺中组成型表达，但仅在植物血凝素刺激的外周血单核细胞中短暂表达。 CCL26 是聚集在 7 号染色体 q 臂上的两个 Cys-Cys 细胞因子基因之一。

Description

在大肠杆菌中产生的 Eotaxin-3 Human Recombinant 是一种单一的、非糖基化的多肽链，含有 71 个氨基酸，分子量为 8.4kDa。
Eotaxin-3 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin-3 in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Eotaxin-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL26 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by: Analysis by RP-HPLC. Analysis by -PAGE.

Amino acid sequence

TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L.

Biological Activity

Determined by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR3. The ED₅₀ for this effect is typically 0.1-1.0 μg/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin Human CHM-256,Eotaxin 人重组

ProSpec-Eotaxin Human CHM-256,Eotaxin 人重组,趋化因子配体 11 是一种小细胞因子，属于 CC 趋化因子家族，也称为 eotaxin。 CCL11 通过诱导其趋化性选择性地募集嗜酸性粒细胞，因此与过敏反应有关。

Eotaxin Human
Eotaxin Human Recombinant
CHM-256
5µg

20µg

1mg

Catalogue number

CHM-256

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11, MGC22554.

Introduction

趋化因子配体 11 是一种小细胞因子，属于 CC 趋化因子家族，也称为 eotaxin。 CCL11 通过诱导其趋化性选择性地募集嗜酸性粒细胞，因此与过敏反应有关。 CCL11 的作用是通过其与称为趋化因子受体的 G 蛋白连接受体的结合来介导的。 CCL11为其配体的趋化因子受体包括CCR2、CCR3和CCR5。人类 CCL11 的基因在三个外显子上编码，位于第 17 号染色体上。

Description

Eotaxin Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids and having a molecular mass of 8345.9 Dalton.
The CCL11 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin Human Recombinant in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Eotaxin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL11 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDICADPKKKWVQD

SMKYLDQKSP TPKP.

Biological Activity

The activity is determined by the chemoattract of human PBE at a concentration between 0.1-10 ng/ml corresponding to a Specific Activity of 100,000-10,000,000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The products may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin Human, His,嗜酸性粒细胞趋化素人重组体 CHM-344

Eotaxin Human, His
Eotaxin Human Recombinant , His Tag
CHM-344
5µg

20µg

1mg

Catalogue number

CHM-344

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11, MGC22554.

Introduction

Description

Eotaxin His Tag Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids fragment corresponding to the mature Eotaxin protein and having a molecular mass of 8345.9 Dalton with an amino-terminal hexahistidine tag.
The Eotaxin-His is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

Eotaxin-His is supplied liquid In Phosphate Buffered Saline pH7.4 containing 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGPASVPTTC CFNLANRKIP LQRLESYRRI TSGKCPQKAV IFKTKLAKDI CADPKKKWVQ DSMKYLDQKS PTPKP

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin Mouse,趋化因子小鼠重组CHM-308

趋化因子配体 11 是一种小细胞因子，属于 CC 趋化因子家族，也称为 eotaxin。 CCL11 通过诱导其趋化性选择性地募集嗜酸性粒细胞，因此与过敏反应有关。ProSpec-Eotaxin Mouse,趋化因子小鼠重组CHM-308

Eotaxin Mouse
Eotaxin Mouse Recombinant
CHM-308
5µg

20µg

1mg

Catalogue number

CHM-308

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11.

Introduction

Description

Eotaxin Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids and having a molecular mass of 8403.2 Dalton.
The CCL11 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a concentrated solution in water containing no additives.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Eotaxin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL11 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be His-Pro-Gly-Ser-Ile.

Biological Activity

The Biological activity was determined by measuring the dose dependent phosphorylation of ERK1 and ERK2 in CCR3 transfected 293 cells. Significant ERK phosphorylation is observed with >100 ng/ml of recombinant mouse eotaxin.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USEONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin Rat,Eotaxin 大鼠重组 CHM-260

ProSpec-Eotaxin Rat,Eotaxin 大鼠重组 CHM-260,CCL11 的作用是通过其与称为趋化因子受体的 G 蛋白连接受体的结合来介导的。 CCL11为其配体的趋化因子受体包括CCR2、CCR3和CCR5。

Eotaxin Rat
Eotaxin Rat Recombinant
CHM-260
5µg

20µg

1mg

Catalogue number

CHM-260

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11.

Introduction

Description

Eotaxin Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 74 amino acids and having a molecular mass of 8.4kDa. The CCL11 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Filtered and lyophilized from a concentrated solution in in 1×PBS, pH7.4.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 Eotaxin 虽然在室温下可稳定保存 3 周，但应在 -18C 以下干燥储存。复溶后，CCL11 应在 4C 下储存 2-7 天，以备将来在 -18C 以下使用。对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

HPGSIPTSCC FTMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTKLGKEICADPKKKWVQD ATKHLDQKLQ TPKP.

Biological Activity

Determined by its ability to chemoattract purified blood eosinophils using a concentration range of 0.1-1.0 ug/ml, corresponding to a Specific Activity of 10-100IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USEONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Eotaxin Rhesus Macaque,Eotaxin 恒河猴重组体 CHM-022

ProSpec-Eotaxin Rhesus Macaque,Eotaxin 恒河猴重组体 CHM-022,趋化因子配体 11 是一种小细胞因子，属于 CC 趋化因子家族，也称为 eotaxin。 CCL11 通过诱导其趋化性选择性地募集嗜酸性粒细胞，因此与过敏反应有关

Eotaxin Rhesus Macaque
Eotaxin Rhesus Macaque Recombinant
CHM-022
5µg

20µg

1mg

Catalogue number

CHM-022

Synonyms

Small inducible cytokine A11, CCL11, Eosinophil chemotactic protein, chemokine ligand 11, SCYA11, MGC22554.

Introduction

Description

Recombinant Eotaxin Rhesus Macaque produced in E.coli cells is a non-glycosylated, homodimeric protein containing 74 amino acid chain and having a molecular mass of 8.4kDa. The Eotaxin is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The Eotaxin was lyophilized from a 0.2µm filtered concentrated solution in 2×PBS, pH 7.0.

Solubility

It is recommended to reconstitute the lyophilized Eotaxin Recombinant in sterile distilled H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 Eotaxin 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重组后，Eotaxin 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

GPDSVATTCC FTLTNKKIPL QRLESYRRII SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDRKSP TPKP

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml corresponding to a specific activity of 1.0 × 10⁵ – 1.0 × 10⁷ IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The products may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Exodus 2 Human,Exodus-2 人类重组CHM-332

ProSpec-Exodus 2 Human,Exodus-2 人类重组CHM-332,CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

Exodus 2 Human
Exodus-2 Human Recombinant
CHM-332
5µg

20µg

1mg

Catalogue number

CHM-332

Synonyms

Small inducible cytokine A21, CCL21, Beta chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC, chemokine ligand 21, ECL, CKb9, TCA4, SCYA21, MGC34555.

Introduction

趋化因子配体 21 是属于 CC 趋化因子家族的小细胞因子。这种趋化因子也称为 6Ckine、exodus-2 和次级淋巴组织趋化因子。 CCL21 主要在淋巴结中表达，与其他 CC 趋化因子相比，它对淋巴细胞具有趋化性。 CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

Description

Exodus-2 Human Recombinant 在大肠杆菌中产生，为单一的非糖基化多肽链，包含 111 个氨基酸，分子量为 12219 道尔顿。
CCL21 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM Phosphate Buffer, pH 7.4 and 150mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Exodus-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P.

Biological Activity

Determined by its ability to chemoattract human total lymphocyte population using a concentration range of 10-100ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Exodus 2 Mouse,Exodus-2 小鼠重组CHM-371

ProSpec-Exodus 2 Mouse,Exodus-2 小鼠重组CHM-371,CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

Exodus 2 Mouse
Exodus-2 Mouse Recombinant
CHM-371
5µg

20µg

1mg

Catalogue number

CHM-371

Synonyms

Small inducible cytokine A21, CCL21, Beta chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC, chemokine ligand 21, ECL, CKb9, TCA4, SCYA21, MGC34555.

Introduction

Description

Exodus-2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 12kDa.
The CCL21 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a concentrated solution in water containing 20mM Phosphate buffer and 0.15M NaCl pH-7.4.

Solubility

It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions

Stability

Purity

Greater than 97.0% as determined by -PAGE & RP-HPLC.

Amino acid sequence

SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG.

Biological Activity

Determined by its ability to chemoattract total murine T cell population using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Exodus-2 Mouse, Sf9,Exodus-2 小鼠重组体，Sf9 CHM-043

ProSpec-Exodus-2 Mouse, Sf9,Exodus-2 小鼠重组体，Sf9 CHM-043,Exodus-2 蛋白或 CCL21 是一种细胞因子，是 CC 趋化因子亚组的一部分。由于其半胱氨酸氨基酸的6个保守残基，该蛋白质也被命名为6Ckine和SLC。

Exodus-2 Mouse, Sf9
Exodus-2 Mouse Recombinant, Sf9
CHM-043
2µg

10µg

100µg

Catalogue number

CHM-043

Synonyms

Ccl21a, C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a,Thymus-derived chemotactic agent 4, TCA4, Ccl21a, Scya21, Scya21a, 6CKBAC2, 6Ckine, ALP,AW987545, CKb9, plt, Scya21b, SLC.

Introduction

Exodus-2 蛋白或 CCL21 是一种细胞因子，是 CC 趋化因子亚组的一部分。由于其半胱氨酸氨基酸的6个保守残基，该蛋白质也被命名为6Ckine和SLC。编码这种蛋白质的基因位于人类的第 9 号染色体上。 Exodus-2 与 CCR7 受体结合，这是一种位于细胞表面的趋化因子受体。

Description

在 Sf9 杆状病毒细胞中产生的 Exodus-2 小鼠重组体是一条含有 119 个氨基酸且分子量为 13.1kDa 的糖基化多肽链。
Exodus-2 在 C 末端与 9 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The Exodus-2 solution contains Phosphate-Buffered Saline and 10% glycerol.

Stability

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

ADPSDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIP AILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSK GCKRTEQTQP SRGHHHHHH

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Fractalkine Human,Fractalkine 人重组体CHM-235

ProSpec-Fractalkine Human,Fractalkine 人重组体CHM-235,Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。 Natural Human Fractalkine 是一种长蛋白，具有延伸的粘蛋白样茎和顶部的趋化因子结构域。

Fractalkine Human
Fractalkine Human Recombinant
CHM-235
5µg

20µg

1mg

Catalogue number

CHM-235

Synonyms

Fractalkine, CX3CL1, Neurotactin, CX3C membrane-anchored chemokine, Small inducible cytokine D1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine.

Introduction

Fractalkine 可溶形式对 t 细胞和单核细胞具有趋化性，但对中性粒细胞不具有趋化性。 Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附。 Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。 Natural Human Fractalkine 是一种长蛋白，具有延伸的粘蛋白样茎和顶部的趋化因子结构域。粘蛋白样茎允许它与细胞表面结合。 Fractalkine 基因与一些称为 CCL17 和 CCL22 的 CC 趋化因子一起位于人类第 16 号染色体上。

Description

Fractalkine Human Recombinant- produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8638 Dalton.
The Fractalkine is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The CX3CL1 was lyophilized from a 0.2μm filtered concentrated solution in 20mM Phosphate buffer, pH 7.4, 50mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CX3CL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CX3CL1 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQW VKDAMQHLDRQAAALTRNG.

Biological Activity

The Biological activity is calculated by its ability to chemoattract human T-Lymphocytes using a concentration range of 5.0-10.0 ng/ml corresponding to a Specific Activity of 100,000-200,000IU/mg.

References

Title: Glial Cell Line-Derived Neurotrophic Factor and Neurturin Inhibit Neurite Outgrowth and Activate RhoA through GFR?2b, an Alternatively Spliced Isoform of GFR?2.
Publication: The Journal of Neuroscience, 23 May 2007, 27: 5603-5614; doi: 10.1523/?JNEUROSCI.4552-06.2007.
Link: http://www.jneurosci.org/content/27/21/5603.full
Applications: GFR?2 when activated by NTN, it inhibits neurite outgrowth induced by GFR?1a, GFR?2a, and GFR?2c isoforms.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Fractalkine Human, His,Fractalkine人重组体CHM-360

ProSpec-Fractalkine Human, His,Fractalkine人重组体CHM-360,Natural Human Fractalkine 是一种长蛋白，具有延伸的粘蛋白样茎和顶部的趋化因子结构域。粘蛋白样茎允许它与细胞表面结合。

Fractalkine Human, His
Fractalkine Human Recombinant , His Tag
CHM-360
2µg

10µg

1mg

Catalogue number

CHM-360

Synonyms

Fractalkine, CX3CL1, Neurotactin, CX3C membrane-anchored chemokine, Small inducible cytokine D1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine.

Introduction

Description

Fractalkine Human Recombinant 在 E.Coli 中产生的 N 端融合了 20 个氨基酸的 His 标签，是一条含有 97 个氨基酸且分子量为 10.9kDa 的单一非糖基化多肽链。
Fractalkine 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

The Fractalkine solution contains Phosphate Buffered Saline pH7.4 and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MQHHGVTKCN ITCSKMTSKI PVALLIHYQQ NQASCGKRAI ILETRQHRLF CADPKEQWVK DAMQHLDRQA AALTRNG.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Fractalkine Human, Sf9,Fractalkine 人重组体，Sf9 CHM-042

ProSpec-Fractalkine Human, Sf9,Fractalkine 人重组体，Sf9 CHM-042,Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附。 Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。

Fractalkine Human, Sf9
Fractalkine Human Recombinant, Sf9
CHM-042
2µg

10µg

100µg

Catalogue number

CHM-042

Synonyms

Fractalkine, CX3CL1, Neurotactin, CX3C membrane-anchored chemokine, Small inducible cytokine D1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine.

Introduction

Fractalkine 可溶形式对 t 细胞和单核细胞具有趋化性，但对中性粒细胞不具有趋化性。 Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附。 Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。 Fractalkine 基因与一些称为 CCL17 和 CCL22 的 CC 趋化因子一起位于人类第 16 号染色体上。

Description

Fractalkine Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 323 amino acids and having a molecular mass of 34.3kDa.
Fractalkine is fused to a 8 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The Fractalkine solution contains 10% Glycerol and Phosphate Buffered Saline .

Stability

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD
AMQHLDRQAA ALTRNGGTFE KQIGEVKPRT TPAAGGMDES VVLEPEATGE SSSLEPTPSS
QEAQRALGTS PELPTGVTGS SGTRLPPTPK AQDGGPVGTE LFRVPPVSTA ATWQSSAPHQ
PGPSLWAEAK TSEAPSTQDP STQASTASSP APEENAPSEG QRVWGQGQSP RPENSLEREE
MGPVPAHTDA FQDWGPGSMA HVSVVPVSSE GTPSREPVAS GSWTPKAEEP IHATMDPQRL GVLITPVPDA QAATRLEHHH HHH

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Fractalkine Mouse,Fractalkine 小鼠重组体 CHM-017

ProSpec-Fractalkine Mouse,Fractalkine 小鼠重组体 CHM-017,Fractalkine 基因与一些称为 CCL17 和 CCL22 的 CC 趋化因子一起位于人类第 16 号染色体上。

Fractalkine Mouse
Fractalkine Mouse Recombinant
CHM-017
5µg

20µg

1mg

Catalogue number

CHM-017

Synonyms

Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Cx3cl1, Cx3c, Fkn, Scyd1, CX3C, ABCD-3, AB030188, AI848747, D8Bwg0439e.

Introduction

Description

在大肠杆菌中产生的 Fractalkine Mouse Recombinant 是一条单一的、非糖基化的多肽链，包含 76 个氨基酸，分子量为 8.7kDa。
CX3CL1 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

QHLGMTKCEI MCGKMTSRIP VALLIRYQLN QESCGKRAIV LETTQHRRFC ADPKEKWVQD AMKHLDHQAA ALTKNG.

Biological Activity

The ED₅₀as determined by a cell proliferation assay using human peripheral blood lymphocytes is less than 0.5 µg/ml, corresponding to a specific activity of > 2000IU/mg.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-Fractalkine Rat,Fractalkine 大鼠重组 CHM-005

ProSpec-Fractalkine Rat,Fractalkine 大鼠重组 CHM-005,Fractalkine 可溶形式对 t 细胞和单核细胞具有趋化性，但对中性粒细胞不具有趋化性。 Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附

Fractalkine Rat
Fractalkine Rat Recombinant
CHM-005
5µg

20µg

1mg

Catalogue number

CHM-005

Synonyms

Fractalkine, CX3CL1, Neurotactin, CX3C membrane-anchored chemokine, Small inducible cytokine D1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine.

Introduction

Description

Fractalkine Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa.
The Fractalkine is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized Fractalkine in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Purity

Greater than 97.0% as determined by -PAGE.

Stability

Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Amino acid sequence

QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG

Biological Activity

Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO a Human,GRO-Alpha 人类重组CHM-329

ProSpec-GRO a Human,GRO-Alpha 人类重组CHM-329,它由人类黑色素瘤细胞分泌，具有促有丝分裂特性，并与黑色素瘤发病机制有关。 CXCL1由巨噬细胞、中性粒细胞和上皮细胞表达，具有中性粒细胞趋化活性。

GRO a Human
GRO-Alpha Human Recombinant
CHM-329
5µg

25µg

1mg

Catalogue number

CHM-329

Synonyms

Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha , chemokine ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.

Introduction

趋化因子配体 1 是一种小细胞因子，属于 CXC 趋化因子家族，以前称为 GRO1 致癌基因、中性粒细胞激活蛋白 3 和黑色素瘤生长刺激活性α。它由人类黑色素瘤细胞分泌，具有促有丝分裂特性，并与黑色素瘤发病机制有关。 CXCL1由巨噬细胞、中性粒细胞和上皮细胞表达，具有中性粒细胞趋化活性。 CXCL1 通过抑制少突胶质细胞前体的迁移在脊髓发育中发挥作用，并参与血管生成、炎症、伤口愈合和肿瘤发生的过程。这种趋化因子通过趋化因子受体 CXCR2 发出信号来引发其作用。 CXCL1 基因位于人类第 4 号染色体上，位于其他 CXC 趋化因子基因中。

Description

在大肠杆菌中产生的 GRO Alpha Human Recombinant 是一种单一的、非糖基化的多肽链，含有 73 个氨基酸，分子量为 7811 道尔顿。
GRO-alpha 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 50mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized GRO-alpha although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Ser-Val-Ala-Thr.

Biological Activity

Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.

References

Title:Deficient inflammatory response to UV radiation in neonatal mice.
Publication:Published online before print March 16, 2007, doi: 10.1189/jlb.1206729 June 2007 Journal of Leukocyte Biology vol. 81 no. 6 1352-1361
Link:http://www.jleukbio.org/content/81/6/1352.full

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO a Human, His CHM-242

ProSpec-GRO a Human, His CHM-242,XCL1 通过抑制少突胶质细胞前体的迁移在脊髓发育中发挥作用，并参与血管生成、炎症、伤口愈合和肿瘤发生的过程。这种趋化因子通过趋化因子受体 CXCR2 发出信号来引发其作用。

GRO a Human, His
GRO-Alpha/MGSA Human Recombinant , His Tag
CHM-242
10µg

50µg

1mg

Catalogue number

CHM-242

Synonyms

Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha, chemokine ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.

Introduction

Description

在大肠杆菌中产生的 CXCL1 Human Recombinant 是一条单一的、非糖基化的多肽链，含有 94 个氨基酸，分子量为 10.1 kDa。 CXCL1 在 N 末端与 20 个氨基酸的 His-Tag 融合，并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CXCL1 in 20mM Tris-HCL pH-8 and 10% glycerol.

Stability

Liquid CXCL1 although stable at 10°C for 1 week, should be stored below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MASVATELRC QCLQTLQGIH PKNIQSVNVK SPGPHCAQTE VIATLKNGRK ACLNPASPIV KKIIEKMLNS DKSN.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO a Rat,GRO-Alpha 大鼠重组 CHM-375

ProSpec-GRO a Rat,GRO-Alpha 大鼠重组 CHM-375,CXCL1 通过抑制少突胶质细胞前体的迁移在脊髓发育中发挥作用，并参与血管生成、炎症、伤口愈合和肿瘤发生的过程。

GRO a Rat
GRO-Alpha Rat Recombinant
CHM-375
5µg

25µg

1mg

Catalogue number

CHM-375

Synonyms

Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha, chemokine ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.

Introduction

Description

CXCL1 Rat Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7.8 kDa.
The Rat CXCL1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH 7.4, and 150mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

冻干的 CXCL1 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。重组后，CXCL1 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK.

Biological Activity

Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO b Human,GRO-Beta人重组CHM-309

ProSpec-GRO b Human,GRO-Beta人重组CHM-309,这种趋化因子由单核细胞和巨噬细胞分泌，对多形核白细胞和造血干细胞具有趋化作用。 CXCL2 的基因位于人类 4 号染色体上的其他 CXC 趋化因子簇中。

GRO b Human
GRO-Beta Human Recombinant
CHM-309
2µg

10µg

1mg

Catalogue number

CHM-309

Synonyms

Macrophage inflammatory protein 2-alpha, MIP2-alpha, CXCL2, Growth- regulated protein beta, Gro-beta, chemokine ligand 2, GRO2, GROb, MIP2, MIP2A, SCYB2, MGSA-b, MIP-2a, CINC-2a, MGSA beta.

Introduction

Chemokine ligand 2 is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha , Growth-regulated protein beta and Gro oncogene-2 . CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1. This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. The gene for CXCL2 is located on human chromosome 4 in a cluster of other CXC chemokines. CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.

趋化因子配体 2 是属于 CXC 趋化因子家族的一种小细胞因子，也称为巨噬细胞炎症蛋白 2-α、生长调节蛋白 β 和 Gro oncogene-2。 CXCL2 在氨基酸序列上与相关趋化因子 CXCL1 有 90% 相同。这种趋化因子由单核细胞和巨噬细胞分泌，对多形核白细胞和造血干细胞具有趋化作用。 CXCL2 的基因位于人类 4 号染色体上的其他 CXC 趋化因子簇中。 CXCL2 通过与称为 CXCR2 的细胞表面趋化因子受体相互作用来动员细胞。

Description

GRO-Beta Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7908 Dalton.
The CXCL2 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The protein was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized GRO-beta Human in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 CXCL2 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。复溶后，CXCL2 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Pro-Leu-Ala-Thr.

Biological Activity

The Biological activity is calculated by its ability to chemoattract CXCR2 transfected 293 cells using 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO b Human His CHM-356,GRO-Beta Human Recombinant , His Tag

ProSpec-GRO b Human His CHM-356,GRO-Beta Human Recombinant , His Tag,CXCL2 的基因位于人类 4 号染色体上的其他 CXC 趋化因子簇中。 CXCL2 通过与称为 CXCR2 的细胞表面趋化因子受体相互作用来动员细胞。

- GRO b Human, His
- GRO-Beta Human Recombinant , His Tag
- CHM-356
- 2µg
  
  10µg
  
  1mg

Catalogue number

CHM-356

Synonyms

Macrophage inflammatory protein 2-alpha, MIP2-alpha, CXCL2, Growth- regulated protein beta, Gro-beta, chemokine ligand 2, GRO2, GROb, MIP2, MIP2A, SCYB2, MGSA-b, MIP-2a, CINC-2a, MGSA beta.

Introduction

Description

GRO-Beta Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 94 amino acids and having a molecular mass of 10.1 kDa. The GRO-b is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

The Human CXCL2 protein solution contains 20mM Tris HCl .

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MAPLATELRC QCLQTLQGIH LKNIQSVKVK SPGPHCAQTE VIATLKNGQK ACLNPASPMV KKIIEKMLKNGKSN.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO b Mouse,GRO-Beta 小鼠重组CHM-338

ProSpec-GRO b Mouse,GRO-Beta 小鼠重组CHM-338,趋化因子配体 2 是属于 CXC 趋化因子家族的一种小细胞因子，也称为巨噬细胞炎症蛋白 2-α、生长调节蛋白 β 和 Gro oncogene-2。 CXCL2 在氨基酸序列上与相关趋化因子 CXCL1 有 90% 相同。

GRO b Mouse
GRO-Beta Mouse Recombinant
CHM-338
5µg

20µg

1mg

Catalogue number

CHM-338

Synonyms

Macrophage inflammatory protein 2-alpha, MIP2-alpha, CXCL2, Growth- regulated protein beta, Gro-beta, chemokine ligand 2, GRO2, GROb, MIP2, MIP2A, SCYB2, MGSA-b, MIP-2a, CINC-2a, MGSA beta.

Introduction

Description

GRO-Beta Mouse Recombinant also caled mouse MIP-2 produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7849 Dalton.
The CXCL2 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The protein was lyophilized from a concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized GRO-beta Mouse in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN.

Biological Activity

The Biological activity was determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml, corresponding to a specific activity of 10⁵-10⁶units/mg.

Protein content

Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280 nm using the absorbency value of 0.015 as the extinction coefficient for a 0.1% solution. This value is calculated by the PC GENE computer analysis program of protein sequences .
2. Analysis by RP-HPLC, using a standard solution of GRO-b as a Reference Standard.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO b Rat,GRO-beta/MIP-2 大鼠重组CHM-372

ProSpec-GRO b Rat,GRO-beta/MIP-2 大鼠重组CHM-372,这种趋化因子由单核细胞和巨噬细胞分泌，对多形核白细胞和造血干细胞具有趋化作用。 CXCL2 的基因位于人类 4 号染色体上的其他 CXC 趋化因子簇中。

GRO b Rat
GRO-beta/MIP-2 Rat Recombinant
CHM-372
5µg

20µg

1mg

Catalogue number

CHM-372

Synonyms

Macrophage inflammatory protein 2-alpha, MIP2-alpha, CXCL2, Growth- regulated protein beta, Gro-beta, chemokine ligand 2, GRO2, GROb, MIP2, MIP2A, SCYB2, MGSA-b, MIP-2a, CINC-2a, MGSA beta, CINC-3.

Introduction

Description

GRO-Beta Rat Recombinant also called Rat MIP-2 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7923 Dalton.
The GRO-b is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

Solubility

It is recommended to reconstitute the lyophilized GRO-beta Rat in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized GRO-b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.

Purity

Greater than 99.0% as determined by -PAGE.

Amino acid sequence

VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN.

Biological Activity

The biological activity was determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml, corresponding to a specific activity of 100,000-1,000,000 units/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO g Human,GRO-伽玛人类重组CHM-310

ProSpec-GRO g Human,GRO-伽玛人类重组CHM-310,CXCR2 的细胞表面趋化因子受体相互作用介导其对靶细胞的影响。 CXCL3 基因位于其他 CXC 趋化因子簇中的 4 号染色体上。

GRO g Human
GRO-Gamma Human Recombinant
CHM-310
2µg

10µg

1mg

Catalogue number

CHM-310

Synonyms

Macrophage inflammatory protein 2-beta, MIP2-beta, CXCL3, Growth-regulated protein gamma, GRO-gamma, GRO-gamma, GRO3, GROg, MIP2B, SCYB3, MIP-2b, CINC-2b, MGSA gamma.

Introduction

趋化因子配体 3 是属于 CXC 趋化因子家族的小细胞因子，也称为 GRO3 癌基因、GRO 蛋白 γ 和巨噬细胞炎症蛋白-2-β。 CXCL3 控制单核细胞的迁移和粘附，并通过与称为 CXCR2 的细胞表面趋化因子受体相互作用介导其对靶细胞的影响。 CXCL3 基因位于其他 CXC 趋化因子簇中的 4 号染色体上。

Description

GRO-Gamma Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7902 Dalton.
The CXCL3 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The protein was lyophilized with no additives.

Solubility

It is recommended to reconstitute the lyophilized CXCL3 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized GRO-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Ser-Val-Val-Thr.

Biological Activity

The Biological activity is calculated by its ability to chemoattract CXCR2 transfected 293 cells using 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec-GRO g Human His CHM-244

ProSpec-GRO g Human His CHM-244,CXCL3 基因位于其他 CXC 趋化因子簇中的 4 号染色体上。

GRO g Human, His
GRO-Gamma Human Recombinant , His Tag
CHM-244
2µg

10µg

1mg

Catalogue number

CHM-244

Synonyms

Macrophage inflammatory protein 2-beta, MIP2-beta, CXCL3, Growth-regulated protein gamma, GRO-gamma, GRO-gamma, GRO3, GROg, MIP2B, SCYB3, MIP-2b, CINC-2b, MGSA gamma.

Introduction

Description

在大肠杆菌中产生的 GRO-Gamma Human Recombinant 是一种单一的、非糖基化的多肽链，含有 94 个氨基酸，分子量为 7902 道尔顿。 GRO-g 在 N 末端与 20 个氨基酸 His-Tag 融合，并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The CXCL3 protein is formulated in 20mM Tris-HCl buffer pH-8, 1mM DTT and 20% glycerol.

Stability

Liquid CXCL3 although stable at 10°C for 1 week, should be stored below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MASVVTELRC QCLQTLQGIH LKNIQSVNVR SPGPHCAQTE VIATLKNGKK ACLNPASPMV QKIIEKILNKGSTN.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Catalogue number

Synonyms

Introduction

Description

Source

Physical Appearance

Formulation

Solubility

Stability

Purity

Amino acid sequence

Biological Activity

Usage

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