Sulfo-Cy7.5 dicarboxylic acid

Sulfo-Cy7.5 dicarboxylic acid,Sulfo-Cy7.5 二羧酸是一种具有两个羧酸基团的双功能近红外荧光染料。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Sulfo-Cyanine7.5 dicarboxylic acid

Sulfo-Cyanine7.5 dicarboxylic acid

标签:Carboxylic acids, Near infrared (NIR) imaging, sulfo-Cy7.5
货号 规格 价格 货期
1382-1mg 1 mg 110.00$ in stock
1382-5mg 5 mg 290.00$ in stock
1382-25mg 25 mg 690.00$ in stock
1382-50mg 50 mg 1270.00$ in stock
1382-100mg 100 mg 1990.00$ in stock
Sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional near infrared fluorescent dye with two carboxylic acid groups.

The reagent is useful as a cross-linker that is NIR emitting. The carboxylic acid groups can be activated by carbodiimide chemistry.

Sulfo-Cy7.5 二羧酸是一种具有两个羧酸基团的双功能近红外荧光染料。

该试剂可用作发射 NIR 的交联剂。 羧酸基团可以通过碳二亚胺化学活化。

Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid

Absorption and emission spectra of sulfo-Cyanine7.5 fluorophore

Sulfo-Cyanine7.5 dicarboxylic acid

Sulfo-Cy7.5 dicarboxylic acid相关产品

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料,用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光,在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团,但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

General properties

Appearance: dark green solid
Molecular weight: 1183.51
Molecular formula: C50H53N2K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

PEG3-Dicarboxylic acid

PEG3-Dicarboxylic acid,PEG3-二羧酸是一种同型双功能接头,在 PEG3 分子的两侧具有两个羧酸基团。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • PEG3-Dicarboxylic acid

PEG3-Dicarboxylic acid

标签:Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
1715-1g 1 g 490.00$ in stock
1715-5g 5 g 890.00$ in stock
1715-10g 10 g 1370.00$ in stock

PEG3-Dicarboxylic acid is a homobifunctional linker with two carboxylic acid groups flanking the PEG3 molecule.

The linker is highly hydrophilic and useful for the conjugation and immobilization of proteins, peptides, and other biomolecules. The carboxy groups can be activated by carbodiimides.
PEG3-二羧酸是一种同型双功能接头,在 PEG3 分子的两侧具有两个羧酸基团。

该接头具有高度亲水性,可用于蛋白质、肽和其他生物分子的缀合和固定。 羧基可以被碳二亚胺活化。

PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid

PEG3-Dicarboxylic acid相关产品

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.

具有末端炔烃功能和羧酸部分的双功能接头,CAS# 1415800-32-6。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

具有叠氮化物和胺基的双功能接头,位于 PEG3(三甘醇)的两侧

General properties

Molecular weight: 294.3
CAS number: 31127-85-2
Molecular formula: C12H22O8
IUPAC name: 3-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, 4,7,10,13-tetraoxahexadecanedioic acid
Solubility: good in water and polar organic solvents
Quality control: NMR 1H
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Iodo-PEG3-Iodide

Iodo-PEG3-Iodide,PEG3 二碘化物是一种具有两个碘化物官能团的同型双功能接头,对许多亲核试剂如硫醇、胺、烷氧基阴离子等具有很强的反应性。可用于合成亲水性对称偶联物。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Iodo-PEG3-Iodide

Iodo-PEG3-Iodide

标签:PEG3 (triethylene glycol), Halogenides, Iodides
货号 规格 价格 货期
2098-1g 1 g 290.00$ in stock

PEG3 diiodide is a homobifunctional linker with two iodide functional groups which are very reactive against many nucleophiles like thiols, amines, alkoxy anions, etc. Can be used to synthesize hydrophilic symmetrical conjugates.

PEG3 二碘化物是一种具有两个碘化物官能团的同型双功能接头,对许多亲核试剂如硫醇、胺、烷氧基阴离子等具有很强的反应性。可用于合成亲水性对称偶联物。

Iodo-PEG3-Iodide Iodo-PEG3-Iodide Iodo-PEG3-Iodide Iodo-PEG3-Iodide

Iodo-PEG3-Iodide相关产品

Iodo-PEG3-Acid

A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.

一种含有羧酸官能团和碘化物、活性卤素基团的双官能化合物。

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头,具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

General properties

Appearance: yellow-brown oil
Molecular weight: 369.97
CAS number: 36839-55-1
Molecular formula: C6H12I2O2
IUPAC name: 1,2-bis(2-iodoethoxy)ethane
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Hydroxy-PEG2-Thiol

Hydroxy-PEG2-Thiol,一种基于短双功能 PEG2 的接头,具有硫醇 (SH) 官能团和 OH 基团。 硫醇是亲核的,并参与与亲电试剂的许多反应。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Hydroxy-PEG2-Thiol

Hydroxy-PEG2-Thiol

标签:Thiol,PEG2 (diethylene glycol)
货号 规格 价格 货期
2389-100mg 100 mg 90.00$ in stock
2389-1g 1 g 270.00$ in stock
A short bifunctional PEG2 based linker with a thiol (SH) functional group and OH group. Thiols are nucleophilic, and participate in many reactions with electrophiles.

Thiols rapidly react with gold surfaces and nanoparticles forming self assembled monolayers (SAMs). Thiol reagent can be used to cover gold with hydrophilic layer.

一种基于短双功能 PEG2 的接头,具有硫醇 (SH) 官能团和 OH 基团。 硫醇是亲核的,并参与与亲电试剂的许多反应。

硫醇与金表面和纳米粒子快速反应形成自组装单分子层 (SAM)。 硫醇试剂可用于用亲水层覆盖金。

Hydroxy-PEG2-Thiol相关产品

ProteOrange protein quantification reagent, 500x

Sensitive fluorescence-based assay reagent 500x concentrate for quantitating purified protein samples. The reagent shows minimal variability for different proteins.

灵敏的荧光检测试剂 500x 浓缩液,用于定量纯化的蛋白质样品。 该试剂显示出不同蛋白质的最小变异性。

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性,与该配体的反应不需要有机助溶剂。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素(一种众所周知的亲和探针)进行点击化学标记的试剂。

General properties

Appearance: colorless liquid
Molecular weight: 122.19
CAS number: 17643-17-3
Molecular formula: C4H10O2S
IUPAC name: 2-(2-sulfanylethoxy)ethanol
Solubility: miscible with water, many organic solvents
Quality control: NMR 1H, GC-MS (95%)
MSDS: Download
Product specifications

Azide-PEG4-Azide

Azide-PEG4-Azide,PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰,或者通过铜催化与末端炔烃的反应,或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG4-Azide

Azide-PEG4-Azide

标签:Azides,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1865-1g 1 g 90.00$ in stock
1865-5g 5 g 250.00$ in stock
1865-25g 25 g 950.00$ in stock
PEG4 diazide is a hydrophilic linker with two azide groups. Both can be modified by Click chemistry, either by a copper catalyzed reaction with terminal alkynes, or by a copper-free reaction with cycloalkynes. Azides can also participate in the Staudinger ligation reaction.

This diazide is useful for the synthesis of dimeric molecules by Click chemistry.

PEG4 二叠氮化物是具有两个叠氮基的亲水接头。 两者都可以通过点击化学进行修饰,或者通过铜催化与末端炔烃的反应,或通过与环炔烃的无铜反应。 叠氮化物也可以参与施陶丁格连接反应。

这种二叠氮化物可用于通过点击化学合成二聚体分子。

Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide Azide-PEG4-Azide

Azide-PEG4-Azide相关产品

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯,用于标记蛋白质、肽和其他分子。

General properties

Appearance: colorless liquid
Molecular weight: 244.25
CAS number: 101187-39-7
Molecular formula: C8H16N6O3
Solubility: miscible with water, polar organic solvents
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Azide-PEG4-Amine

Azide-PEG4-Amine,低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å,因此 PEG4 的长度约为 14 Å (1.4 nm)。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG4-Amine

Azide-PEG4-Amine

标签:Azides,Amines,Click chemistry,Cross linking reagents,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
1868-1g 1 g 90.00$ in stock
1868-5g 5 g 250.00$ in stock
1868-25g 25 g 950.00$ in stock
Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so that the length of PEG4 is around 14 Å (1.4 nm).

Azide-PEG4-Amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds, and an azide group that is suitable for Click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

低聚乙二醇是通用的亲水性接头。 每个单体的长度为 3.43 Å,因此 PEG4 的长度约为 14 Å (1.4 nm)。

叠氮化物-PEG4-Amine 是一种双官能化合物,具有可通过活化酯或类似羰基化合物酰化修饰的胺基,以及适用于 Click 化学反应的叠氮基。 PEG4 具有高度亲水性和生物相容性。

Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine Azide-PEG4-Amine

Azide-PEG4-Amine相关产品

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

一种双功能连接分子,包含用于点击化学的末端炔烃部分和胺基。 包含一个长的亲水性 PEG4 臂。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能,用于将环辛炔连接到各种分子上。

General properties

Appearance: colorless to yellowish liquid
Molecular weight: 218.25
CAS number: 134179-38-7
Molecular formula: C8H18N4O3
Solubility: miscible with water, polar organic solvents
Quality control: NMR 1H,GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid,Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的,适合合成水溶性结合物。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid

标签:Azides,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
2558-1g 1 g 265.00$ in stock
2558-5g 5 g 950.00$ in stock
Azide-PEG3-Carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.

This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (Click Chemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的,适合合成水溶性结合物。

叠氮基可以与含有炔烃部分的生物分子发生[3+2]-偶极环加成反应(点击化学反应),羧基可以被活化并与各种胺反应。

合成的生物偶联物的库可以非常广泛; 例如,可以使用这种方法生成不同的抗体-药物偶联物 (ADC)。 此外,PEG 接头与分子的缀合可以增加其在水中的稳定性和溶解度,并降低免疫原性。

Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid相关产品

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.

具有末端炔烃功能和羧酸部分的双功能接头,CAS# 1415800-32-6。

Azide-PEG3-OH

Azide-PEG3-OH is a bifunctional molecule with azide group, primary alcohol, and a hydrophilic linker in between.

叠氮化物-PEG3-OH 是一种双功能分子,具有叠氮基、伯醇和介于两者之间的亲水性接头。

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

General properties

Appearance: colorless liquid
Molecular weight: 247.25
CAS number: 1056024-94-2
Molecular formula: C9H17N3O5
IUPAC name: 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Azide-PEG3-Azide

Azide-PEG3-Azide,PEG3(三甘醇)二叠氮化物(1,8-diazido-3,6-dioxaoctane)是一种对称的双功能交联剂,带有两个叠氮基。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Azide

Azide-PEG3-Azide

标签:Azides,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
207-1g 1 g 95.00$ in stock
207-5g 5 g 390.00$ in stock
207-25g 25 g please inquire in stock
PEG3 (triethylene glycol) diazide (1,8-diazido-3,6-dioxaoctane) is a symmetrical bifunctional crosslinker bearing two azide groups.
PEG3(三甘醇)二叠氮化物(1,8-diazido-3,6-dioxaoctane)是一种对称的双功能交联剂,带有两个叠氮基。

Azide-PEG3-Azide Azide-PEG3-Azide Azide-PEG3-Azide > Azide-PEG3-Azide

Azide-PEG3-Azide相关产品

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 200.2
CAS number: 59559-06-7
Molecular formula: C6H12N6O2
IUPAC name: 1,8-diazido-3,6-dioxaoctane, 1,2-bis(2-azidoethoxy)ethane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

相关文献:

  1. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  2. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f

Azide-PEG3-Amine

Azide-PEG3-Amine,叠氮化物-PEG3-胺是一种双功能试剂,具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物(通过胺基的酰化)与炔烃(通过点击化学反应)的缀合。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-Amine

Azide-PEG3-Amine

标签:Azides,Amines,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
218-1g 1 g 95.00$ in stock
218-5g 5 g 280.00$ in stock
218-25g 25 g please inquire in stock
Azide-PEG3-amine is a bifunctional reagent with an azide group, and an amine group flanking triethylene glycol. This linker is useful for the conjugation of carboxylic derivatives (by acylation of the amine group) with alkynes (via a Click chemistry reaction).
叠氮化物-PEG3-胺是一种双功能试剂,具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物(通过胺基的酰化)与炔烃(通过点击化学反应)的缀合。

Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine

Azide-PEG3-Amine相关产品

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

General properties

Appearance: colorless/yellowish oil
Molecular weight: 174.2
CAS number: 166388-57-4
Molecular formula: C6H14N4O2
IUPAC name: 1-Amino-8-azido-3,6-dioxaoctane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GCMS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Amine-PEG4-OH

Amine-PEG4-OH,该化合物是一种 PEG 接头,具有四个单体单元 (PEG4),具有末端羟基和氨基,用于生物分子缀合。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Amine-PEG4-OH

Amine-PEG4-OH

标签:Amines,PEG4 (tetraethylene glycol)
货号 规格 价格 货期
2473-1g 1 g 190.00$ in stock
2473-5g 5 g 490.00$ 10 days
2473-25g 25 g please inquire in stock
This compound is a PEG-linker with four monomer units (PEG4) with terminal hydroxy and amino groups for biomolecule conjugation.

Primary amines readily react with activated carboxyl groups, and the terminal hydroxyl group in the crosslinker can react with esters, azides, amines, and halogen derivatives in various conditions.

Polyethylene glycol linkers have low molecular weight, are non-toxic, and form conjugates with increased solubility. The field of use of these molecules is rather wide, varying from synthesis of new polymers to biomedicine.

该化合物是一种 PEG 接头,具有四个单体单元 (PEG4),具有末端羟基和氨基,用于生物分子缀合。

伯胺很容易与活化的羧基反应,而交联剂中的末端羟基可以在各种条件下与酯、叠氮化物、胺和卤素衍生物发生反应。

聚乙二醇接头具有低分子量、无毒且可形成溶解度增加的缀合物。 这些分子的使用领域相当广泛,从新聚合物的合成到生物医学都有所不同。

Amine-PEG4-OH Amine-PEG4-OH Amine-PEG4-OH Amine-PEG4-OH

Amine-PEG4-OH相关产品

Amine-PEG3-carboxylic acid, hydrochloride

Hydrophilic linker with amino and carboxyl groups.

具有氨基和羧基的亲水接头。

General properties

Appearance: colorless to yellowish oil
Molecular weight: 193.24
CAS number: 86770-74-3
Molecular formula: C8H19NO4
IUPAC name: 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethanol
Solubility: miscible with water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
MSDS: Download
Product specifications

Amine-PEG3-carboxylic acid, hydrochloride

Amine-PEG3-carboxylic acid, hydrochloride,胺-PEG3-羧酸是一种含有末端羧基和氨基的双功能PEG3衍生物。 亲水性 PEG3 间隔物易溶于水。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Amine-PEG3-carboxylic acid, hydrochloride

Amine-PEG3-carboxylic acid, hydrochloride

标签:Amines,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
2719-1g 1 g 230.00$ in stock
Amine-PEG3-carboxylic acid is a bifunctional PEG3-derivative containing terminal carboxyl and amino groups. Hydrophilic PEG3 spacer is freely soluble in water.

The terminal amino group can react with activated esters, carbonyl compounds, and carbonic acids, e.g. in reductive amination reactions.

The carbonyl group in amine-PEG3-carboxylic acid can react with primary amino groups in the presence of activators (carbodiimides or HATU) resulting in a stable amide bond.

胺-PEG3-羧酸是一种含有末端羧基和氨基的双功能PEG3衍生物。 亲水性 PEG3 间隔物易溶于水。

末端氨基可与活化酯、羰基化合物和碳酸反应,例如 在还原胺化反应中。

胺-PEG3-羧酸中的羰基可在活化剂(碳二亚胺或 HATU)存在下与伯氨基反应,形成稳定的酰胺键。

Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride

Amine-PEG3-carboxylic acid, hydrochloride相关产品

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

Azide-PEG3-Carboxylic acid

Bifunctional triethylene glycol with terminal carboxyl and azido groups.

具有末端羧基和叠氮基的双官能三甘醇。

General properties

Appearance: yellowish oil
Molecular weight: 257.71
CAS number: 127457-79-8
Molecular formula: C9H20NClO5
IUPAC name: 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid;hydrochloride
Solubility: soluble in water
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Alkyne-PEG3-amine

Alkyne-PEG3-amine,Alkyne-PEG3-amine 是一种基于三甘醇 (PEG3) 支架的异双功能分子。 它含有胺和炔官能团。 前者可以与各种亲电试剂结合。 后者适用于铜催化点击化学和 Sonogashira 偶联。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Alkyne-PEG3-amine

Alkyne-PEG3-amine

标签:Alkynes,Amines,PEG3 (triethylene glycol)
货号 规格 价格 货期
425-1g 1 g 195.00$ in stock
425-5g 5 g 580.00$ in stock
Alkyne-PEG3-amine is a heterobifunctional molecule based on triethyleneglycol (PEG3) scaffold. It contains amine and alkyne functional groups. The former can be conjugated with various electrophiles. The latter is suitable for copper catalyzed Click chemistry and Sonogashira coupling.

PEG linkers are hydrophilic linkers of choice for the conjugation of biomolecules.

Alkyne-PEG3-amine 是一种基于三甘醇 (PEG3) 支架的异双功能分子。 它含有胺和炔官能团。 前者可以与各种亲电试剂结合。 后者适用于铜催化点击化学和 Sonogashira 偶联。

PEG接头是生物分子缀合的亲水接头。

Alkyne-PEG3-amine Alkyne-PEG3-amine Alkyne-PEG3-amine Alkyne-PEG3-amine

Alkyne-PEG3-amine相关产品

Alkyne-PEG3-NHS ester

Bifunctional hyrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).

基于三甘醇 (PEG3) 的具有 NHS 酯和末端炔烃官能团的双功能亲水接头。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头,具有羟基和炔烃片段。

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

一种双功能连接分子,包含用于点击化学的末端炔烃部分和胺基。 包含一个长的亲水性 PEG4 臂。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 187.24
CAS number: 932741-19-0
Molecular formula: C9H17NO3
Solubility: mixable with water, good in polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Alkyne-PEG3-OH

Alkyne-PEG3-OH,炔烃 PEG3 OH(单炔丙基三甘醇)是一种基于双功能 PEG3 的接头,具有炔烃和 OH 基团。 它可用于将炔基添加到各种分子中,以用于随后的点击化学应用。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Alkyne-PEG3-OH

Alkyne-PEG3-OH

标签:Alkynes,PEG3 (triethylene glycol)
货号 规格 价格 货期
418-1g 1 g 95.00$ in stock
418-5g 5 g 280.00$ in stock
418-25g 25 g please inquire in stock
Alkyne PEG3 OH (mono-propargyl triethylene glycol) is a bifunctional PEG3 based linker with both an alkyne and an OH group. It can be used to add alkyne groups to various molecules for subsequent Click chemistry applications.
炔烃 PEG3 OH(单炔丙基三甘醇)是一种基于双功能 PEG3 的接头,具有炔烃和 OH 基团。 它可用于将炔基添加到各种分子中,以用于随后的点击化学应用。

Alkyne-PEG3-OH Alkyne-PEG3-OH Alkyne-PEG3-OH Alkyne-PEG3-OH

Alkyne-PEG3-OH相关产品

Alkyne maleimide

Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.

用于将炔官能团连接到蛋白质、肽和其他带有 SH(硫醇)基团(包括半胱氨酸残基)的分子上的马来酰亚胺试剂。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

General properties

Appearance: colorless to yellow oil
Molecular weight: 188.22
CAS number: 208827-90-1
Molecular formula: C9H16O4
IUPAC name: 2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanol, 3,6,9-trioxadodecyne-11-ol-1
Solubility: good in most organic solvents and water
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Alkyne-PEG3-COOH

Alkyne-PEG3-COOH,Alkyne-PEG3-COOH 是一种带有羧基和炔烃部分的双功能三甘醇衍生物。 前者可以用肽偶联试剂(如 PyBOP)或碳二亚胺(如 EDC)活化,与胺形成稳定的酰胺键。 炔基可以在 CuAAc 反应中与叠氮化物偶联。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Alkyne-PEG3-COOH

Alkyne-PEG3-COOH

标签:Alkynes,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
1743-1g 1 g 490.00$ in stock
1743-5g 5 g 980.00$ in stock
1743-25g 25 g please inquire in stock
Alkyne-PEG3-COOH is a bifunctional triethyleneglycol derivative bearing a carboxy group, and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAc reaction.

PEGs are hydrophilic linkers that are useful in the synthesis of water soluble conjugates.

Alkyne-PEG3-COOH 是一种带有羧基和炔烃部分的双功能三甘醇衍生物。 前者可以用肽偶联试剂(如 PyBOP)或碳二亚胺(如 EDC)活化,与胺形成稳定的酰胺键。 炔基可以在 CuAAc 反应中与叠氮化物偶联。

PEG是可用于合成水溶性缀合物的亲水性接头。

Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH

Alkyne-PEG3-COOH相关产品

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.

Sulfo-Cy5 是一种用于 Click 化学的水溶性 Cy5 染料炔烃。

Azide-PEG4-Amine

PEG4 amine azide (CAS# 134179-38-7) is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.

PEG4 amine azide (CAS# 134179-38-7) 是一种具有胺和叠氮化物官能团的双功能接头。 它基于四甘醇核心。 PEG4 接头的长度为 1.4 nm。

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

General properties

Appearance: colorless to yellow oil
Molecular weight: 246.26
CAS number: 1415800-32-6
Molecular formula: C11H18O6
IUPAC name: 3,6,9,12-tetraoxapentadecyn-15-oic acid
Solubility: good in most organic solvents and water
Quality control: NMR 1H, GC-MS (95%, as Me ester)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

相关文献:

  1. Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980

Alkyne-PEG2-iodide

Alkyne-PEG2-iodide,具有末端炔烃和烷基碘基团的双功能 PEG2 基交联剂。烷基碘是最强大的烷基化剂之一。 它们使各种 O-、S-、N- 和 C- 亲核体烷基化。 这种反应性衍生物可用于制备具有末端炔基的不同分子。 末端炔烃是一种多功能合成子,可参与 Sonogashira 偶联和点击化学反应。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Alkyne-PEG2-iodide

Alkyne-PEG2-iodide

标签:Alkynes,Halogenides,PEG2 (diethylene glycol)
货号 规格 价格 货期
2136-1g 1 g 490.00$ in stock
Bifunctional PEG2-based crosslinker having terminal alkyne and alkyl iodide groups.

Alkyl iodides are among the most powerful alkylators. They alkylate various O-, S-, N- and C-nuclophiles. This reactive derivative can be used for the preparation of different molecules with terminal alkyne group. Terminal alkyne is a versatile synthon that participates in Sonogashira coupling and Click chemistry reaction.

具有末端炔烃和烷基碘基团的双功能 PEG2 基交联剂。烷基碘是最强大的烷基化剂之一。 它们使各种 O-、S-、N- 和 C- 亲核体烷基化。 这种反应性衍生物可用于制备具有末端炔基的不同分子。 末端炔烃是一种多功能合成子,可参与 Sonogashira 偶联和点击化学反应。

Alkyne-PEG2-iodide Alkyne-PEG2-iodide Alkyne-PEG2-iodide Alkyne-PEG2-iodide

Alkyne-PEG2-iodide相关产品

Iodo-PEG2-azide

A bifunctional molecule containing hydrophilic PEG2 with azide and iodide groups.
一种双功能分子,含有具有叠氮化物和碘化物基团的亲水性 PEG2。

Alkyne-PEG3-Iodide

PEG3 with alkyne and iodide functional groups, a reactive and hydrophilic linker for alkylation and Click chemistry.
具有炔烃和碘化物官能团的 PEG3,一种用于烷基化和点击化学的反应性和亲水性接头。

Iodo-PEG3-Iodide

Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.

具有卤素反应基团的基于同双功能 PEG3 的接头可用于亲核试剂的交联。

General properties

Appearance: colorless to yellow oil
Molecular weight: 254.07
CAS number: 1234387-33-7
Molecular formula: C7H11IO2
IUPAC name: 3-(2-(2-iodoethoxy)ethoxy)prop-1-yne
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Alkyne-PEG2-amine

Alkyne-PEG2-amine,PEG是用于生物缀合的有用的亲水性接头。 二甘醇或 PEG2 是一种短 PEG 接头。 这种双功能分子具有一个氨基,可以与酸酐和活化酯进行酰化反应,与醛和酮进行还原胺化,与卤化物和环氧化物进行烷基化,仅举几例。 其末端炔基在铜催化的 CuAAc 反应中与叠氮化物反应,在钯催化的 Sonogashira 与芳基卤化物和乙烯基卤化物和三氟甲磺酸酯偶联。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Alkyne-PEG2-amine

Alkyne-PEG2-amine

标签:Alkynes,Amines,PEG2 (diethylene glycol)
货号 规格 价格 货期
2065-1g 1 g 120.00$ in stock
2065-5g 5 g 350.00$ in stock
2065-25g 25 g please inquire in stock
PEGs are useful hydrophilic linkers for the bioconjugation. Diethyleneglycol, or PEG2, is a short PEG linker. This bifunctional molecule has an amino group that can be engaged in acylation reaction with anhydrides and activated esters, reductive amination with aldehydes and ketones, and alkylation with halogenides and epoxides, just to list a few reactions. Its terminal alkyne group reacts with azides in copper-catalyzed CuAAc reaction, and palladium-catalyzed Sonogashira coupling with aryl- and vinyl halides and triflates.
PEG是用于生物缀合的有用的亲水性接头。 二甘醇或 PEG2 是一种短 PEG 接头。 这种双功能分子具有一个氨基,可以与酸酐和活化酯进行酰化反应,与醛和酮进行还原胺化,与卤化物和环氧化物进行烷基化,仅举几例。 其末端炔基在铜催化的 CuAAc 反应中与叠氮化物反应,在钯催化的 Sonogashira 与芳基卤化物和乙烯基卤化物和三氟甲磺酸酯偶联。

Alkyne-PEG2-amine Alkyne-PEG2-amine Alkyne-PEG2-amine

Alkyne-PEG2-amine相关产品

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头,具有羟基和炔烃片段。

General properties

Appearance: colorless to yellow liquid
Molecular weight: 143.18
CAS number: 944561-44-8
Molecular formula: C7H13NO2
IUPAC name: 2-[2-(2-propynyloxy)ethoxy]ethylamine
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
MSDS: Download
Product specifications

Azide-PEG3-OH

Azide-PEG3-OH,储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

  • Products
  • Miscellaneous reagents
  • Bifunctional crosslinkers
  • Azide-PEG3-OH

Azide-PEG3-OH

标签:Azides, PEG3 (triethylene glycol),Bifunctional crosslinkers
货号 规格 价格 货期
1742-1g 1 g 90.00$ in stock

Heterobifunctional crosslinker with a primary alcohol functional group, azide group, and a PEG3 hydrophilic linker.

具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

Azide-PEG3-OH相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cyanine5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头,具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

General properties

Appearance: colorless liquid 无色液体
Molecular weight: 175.19
CAS number: 86520-52-7
Molecular formula: C6H13N3O3
IUPAC name: 2-[2-(2-azidoethoxy)ethoxy]-ethanol
Solubility: miscible with water, most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications