Hampton蛋白结晶试剂盒Sodium formate/HR2-547/HR2-765

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Products > Optimize Reagents > Optimize – Salts > Sodium formate

Sodium formate

CAT NO

HR2-547

NAME

7.0 M Sodium formate

DESCRIPTION

200 mL

PRICE

$93.00

CAT NO

HR2-765

NAME

5.0 M Sodium formate pH 7.0

DESCRIPTION

200 mL

PRICE

$94.00

支持材料

HR2-547 Sodium formate 7.0 M solution SDS

HR2-765 Sodium formate pH 7.0 5.0 M solution SDS

应用

Crystallization grade Sodium formate for formulating screens or for optimization
结晶级甲酸钠，用于筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium formate

Synonyms: Formic acid sodium salt
CHNaO₂
HCOONa
M_r 68.01
CAS [141-53-7]
EC Number 205-488-0
Beilstein Registry Number 3595134
Merck 14,8621
RTECS LR0350000
MDL Number MFCD00013101
PubChem Substance ID 24886222
Purity ≥ 99.0%

HR2-547 pH Range: 8.2 – 9.5 at 25°C
HR2-547 Measured Conductivity Range: 107.5 – 121.7 mS/cm at 25°C
HR2-547 Measured Refractive Index Range: 1.38014 – 1.38055 at 20°C

HR2-765 is titrated to pH 7.0 using HCl
HR2-765 Measured Conductivity Range: 121.8 – 137.3 mS/cm at 25°C
HR2-765 Measured Refractive Index Range: 1.36867 – 1.36929 at 20°C

别名：甲酸钠盐
CHNaO2
HCOONa
68.01 先生
中国科学院 [141-53-7]
欧盟编号 205-488-0
贝尔斯坦注册号 3595134
默克 14,8621
RTECS LR0350000
MDL 编号 MFCD00013101
PubChem 物质 ID 24886222
纯度≥99.0%

HR2-547 pH 范围：25°C 时为 8.2 – 9.5
HR2-547 测量电导率范围：107.5 – 121.7 mS/cm，25°C
HR2-547 测量的折射率范围：20°C 时为 1.38014 – 1.38055

使用 HCl 将 HR2-765 滴定至 pH 7.0
HR2-765 测量的电导率范围：25°C 时为 121.8 – 137.3 mS/cm
HR2-765 测量的折射率范围：20°C 时为 1.36867 – 1.36929

Total Impurities: Insoluble matter, passes filter test
Al ≤0.0005%
As ≤0.00001%
Ba ≤0.0005%
Bi ≤0.0005%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.01%
Li ≤0.0005%
Mg ≤0.0005%
Mn ≤0.0005%
Mo ≤0.0005%
Ni ≤0.0005%
Pb ≤0.0005%
SO₄ ≤0.005%
Sr ≤0.0005%
Zn ≤0.0005%

参考Sodium formate

1. Crystal structure of the cytoplasmic domain of the chloride channel CIC-0. Sebastian Meyer and Raimund Dutzler. Structure 14, 299-307, February 2006.

1. 氯离子通道 CIC-0 胞质结构域的晶体结构。塞巴斯蒂安迈耶和雷蒙德杜茨勒。结构 14，299-307，2006 年 2 月。

DESCRIPTION

200 mL

PRICE

$107.00

支持材料

HR2-747 Sodium malonate pH 4.0 SDS

HR2-749 Sodium malonate pH 5.0 SDS

HR2-751 Sodium malonate pH 6.0 SDS

HR2-707 Sodium malonate pH 7.0 SDS

HR2-807 Sodium malonate pH 8.0 SDS

pH/Dilution Table for Sodium Malonate

应用

Crystallization grade Sodium malonate for formulating screens or for optimization
用于配制筛选或优化的结晶级丙二酸钠

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述

The Sodium malonate offered by Hampton Research is Malonic acid (CAS Number 141-82-2) titrated to pH 4.0-8.0 using Sodium hydroxide as described in the publication “A comparison of salts for the crystallization of macromolecules. Alexander McPherson. Protein Science (2001), 10:418-422.”. In this same publication, Sodium malonate was reported to be more successful than any other salt, resulting in the crystallization of 19 of the 23 macromolecules, almost twice as effective as the next most successful salt, which was a draw between sodium acetate, sodium tartrate, sodium formate, and ammonium sulfate. The high success rate of Sodium malonate in producing crystals was even more impressive when an overall unique success rate with individual macromolecules was considered.

The use of Sodium malonate in place of Ammonium sulfate has been reported in one instance to improve the reproducibility of crystals and improve resistance to physicochemical shocks. Sodium malonate also acted as a good cryoprotectant (Xing and Xu 2003).

One may combine the four different sodium malonate stocks to create a pH versus sodium malonate concentration grid for screening or optimization. Refer to the pH/Dilution Table for Sodium malonate.

Based on the structure of malonic acid titrated with sodium hydroxide, there are no chiral carbons so it is not characterized as having enantiomeric structures, such as D or L.

Hampton Research 提供的丙二酸钠是使用氢氧化钠滴定至 pH 4.0-8.0 的丙二酸（CAS 编号 141-82-2），如出版物“用于大分子结晶的盐的比较。Alexander McPherson。蛋白质科学（ 2001), 10:418-422”。在同一份出版物中，据报道丙二酸钠比任何其他盐更成功，导致 23 种大分子中的 19 种结晶，几乎是下一个最成功的盐的两倍，后者是乙酸钠和酒石酸钠之间的抽吸、甲酸钠和硫酸铵。当考虑到单个大分子的整体独特成功率时，丙二酸钠在生产晶体中的高成功率更加令人印象深刻。

据报道，在一个实例中使用丙二酸钠代替硫酸铵可提高晶体的再现性并提高对物理化学冲击的抵抗力。丙二酸钠也是一种很好的冷冻保护剂（Xing and Xu 2003）。

可以将四种不同的丙二酸钠库存组合起来，以创建一个 pH 值与丙二酸钠浓度网格，以进行筛选或优化。请参阅丙二酸钠的 pH/稀释表。

根据用氢氧化钠滴定的丙二酸的结构，没有手性碳，因此不具有对映异构体结构的特征，例如 D 或 L。

Synonyms: Propanedioic acid or Malonic acid
C₃H₄O₄ (before titration with NaOH)
M_r 104.06 (before titration with NaOH)
CAS Number 141-82-2
EC Number 205-503-0
Beilstein Registry Number 1751370
Merck 14,5710
RTECS OO0175000
MDL Number MFCD00002707
Purity > 99.0%
pKa1 2.8
pKa2 5.7

HR2-747 Measured Conductivity Range: 73.3 – 75.3 mS/cm at 25°C
HR2-747 Measured Refractive Index Range: 1.38365 – 1.38425 at 20°C

HR2-749 Measured Conductivity Range: 77.2 – 78.0 mS/cm at 25°C
HR2-749 Measured Refractive Index Range: 1.39264 – 1.39300 at 20°C

HR2-751 Measured Conductivity Range: 73.4 – 75.2 mS/cm at 25°C
HR2-751 Measured Refractive Index Range: 1.39938 – 1.39973 at 20°C

HR2-707 Measured Conductivity Range: 71.0 – 73.7 mS/cm at 25°C
HR2-707 Measured Refractive Index Range: 1.40090 – 1.40098 at 20°C

HR2-807 Measured Conductivity Range: 71.8 – 75.0 mS/cm at 25°C
HR2-807 Measured Refractive Index Range: 1.40106 – 1.40115 at 20°C

参考Sodium malonate

1. A comparison of salts for the crystallization of macromolecules. Alexander McPherson. Protein Science (2001), 10:418-422.

2. Crystallization of the PX domain of cytokine-independent survival kinase (CISK): improvement of crystal quality for X-ray diffraction with sodium malonate. Yi Xing and Wenqing Xu. Acta Cryst. (2003). D59, 1816-1818.

3. Malonate: a versatile cryoprotectant and stabilizing solution for salt-grown macromolecular crystals. T. Holyoak, T. D. Fenn, M. A. Wilson, A. G. Moulin, D. Ringe and G. A. Petsko. Acta Cryst. (2003). D59, 2356-2358.

4. Purification, crystallization and preliminary crystallographic analysis of Est25: a ketoprofen-specific hormone-sensitive lipase. Kim et al Acta Cryst. (2007). F63, 579–581.

1. 大分子结晶盐的比较。亚历山大·麦克弗森。蛋白质科学（2001），10：418-422。

2. 不依赖细胞因子的存活激酶 (CISK) 的 PX 结构域的结晶：用丙二酸钠改善 X 射线衍射的晶体质量。艺兴和徐文清。晶体学报。（2003 年）。 D59，1816-1818。

3. 丙二酸盐：一种用于盐生大分子晶体的多功能冷冻保护剂和稳定剂。 T. Holyoak、T. D. Fenn、M. A. Wilson、A. G. Moulin、D. Ringe 和 G. A. Petsko。晶体学报。（2003 年）。 D59，2356-2358。

4. Est25 的纯化、结晶和初步晶体学分析：一种酮洛芬特异性激素敏感性脂肪酶。 Kim等人Acta Cryst。（2007 年）。 F63, 579–581。

Hampton蛋白结晶试剂盒Sodium nitrate/HR2-661

Products > Optimize Reagents > Optimize – Salts > Sodium nitrate

Sodium nitrate

CAT NO

HR2-661

NAME

7.0 M Sodium nitrate

DESCRIPTION

200 mL

PRICE

$104.00

支持材料

HR2-661 Sodium nitrate SDS

应用

Crystallization grade Sodium nitrate for formulating screens or for optimization
结晶级硝酸钠，用于筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium nitrate

Synonyms: Chile salpeter
NaNO₃
NNaO₃
M_r 84.99
CAS Number [7631-99-4]
EC Number 231-554-3
Merck 14,8647
RTECS WC5600000
MDL Number MFCD00011119
PubChem Substance ID 24886299
Purity ≥ 99.0%
UN Number 1498 5.1/PG 3

Measured pH range: 5.0 – 8.5 at 25°C
Measured Conductivity Range: 174.4 – 198.7 mS/cm at 25°C
Measured Refractive Index Range: 1.38541 – 1.38576 at 20°C

同义词：智利salpeter
NaNO3
NNaO3
84.99 先生
CAS 编号 [7631-99-4]
欧盟编号 231-554-3
默克 14,8647
RTECS WC5600000
MDL 编号 MFCD00011119
PubChem 物质 ID 24886299
纯度≥99.0%
联合国编号 1498 5.1/PG 3

测得的 pH 值范围：25°C 时 5.0 – 8.5
测得的电导率范围：25°C 时为 174.4 – 198.7 mS/cm
测得的折射率范围：20°C 时为 1.38541 – 1.38576

Al ≤0.0005%
As ≤0.00001%
Ba ≤0.0005%
Bi ≤0.0005%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.0005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0002%
IO₃ ≤0.0005%
K ≤0.005%
Li ≤0.0005%
Mg ≤0.0005%
Mn ≤0.0005%
Mo ≤0.0005%
NH₄⁺ ≤0.002%
Ni ≤0.0005%
NO₂ ≤0.001%
Pb ≤0.0005%
PO₄ ≤0.0002%
SO₄ ≤0.003%
Sr ≤0.0005%
Zn ≤0.0005%

参考Sodium nitrate

1. Tuna cytochrome c at 2.0 A resolution. Swanson, R; Trus, BL; Mandel, N; Mandel, G; Kallai, OB; Dickerson, RE. J Biol Chem 252, 759- 775, 1977.

1. 分辨率为 2.0 A 的金枪鱼细胞色素 c。斯旺森，R；特鲁斯，BL；曼德尔，N；曼德尔，G；卡莱，OB；迪克森，RE。生物化学杂志 252, 759-775, 1977。

Hampton蛋白结晶试剂盒Sodium phosphate dibasic dihydrate/HR2-639

Products > Optimize Reagents > Optimize – Salts > Sodium phosphate dibasic dihydrate

Sodium phosphate dibasic dihydrate

CAT NO

HR2-639

NAME

1.0 M Sodium phosphate dibasic dihydrate

DESCRIPTION

200 mL

PRICE

$125.00

支持材料

HR2-639 Sodium phosphate dibasic dihydrate SDS

应用

Crystallization grade Sodium phosphate dibasic dihydrate for formulating screens or for optimization
结晶级磷酸氢二钠二水合物，用于配制筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium phosphate dibasic dihydrate

Synonyms: sec-Sodium phosphate or di-sodium hydrogen phosphate dihydrate or disodium hydrogen phosphate dihydrate or disodium phosphate
HNa₂O₄P • 2H₂O
Na₂HPO₄• 2H₂O
M_r 177.99
CAS Number [10028-24-7]
EC Number 231-448-7
Merck 14,8659
MDL Number MFCD00149182
PubChem Substance ID 24886241
Purity ≥ 99.0%

Measured pH Range: 8.7 – 8.9 at 25°C
Measured Conductivity Range: 61.9 – 69.0 mS/cm at 25°C
Measured Refractive Index Range: 1.35644 – 1.35717 at 20°C

别名：磷酸二钠或磷酸氢二钠二水合物或磷酸氢二钠二水合物或磷酸二钠
HNa2O4P • 2H2O
Na2HPO4 • 2H2O
177.99 先生
CAS 编号 [10028-24-7]
欧盟编号 231-448-7
默克 14,8659
MDL 编号 MFCD00149182
PubChem 物质 ID 24886241
纯度≥99.0%

测得的 pH 值范围：25°C 时 8.7 – 8.9
测得的电导率范围：25°C 时为 61.9 – 69.0 mS/cm
测得的折射率范围：20°C 时为 1.35644 – 1.35717

Al ≤0.0005%
As ≤0.00001%
Ba ≤0.0005%
Bi ≤0.0005%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.001%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.005%
Li ≤0.0005%
Mg ≤0.0005%
Mn ≤0.0005%
Mo ≤0.0005%
N ≤0.001%
Ni ≤0.0005%
Pb ≤0.0005%
SO₄ ≤0.005%
Sr ≤0.0005%
Zn ≤0.0005%

1.0 M Sodium phosphate dibasic dihydrate is completely soluble in water at 4 degrees Celsius and higher temperatures. Below 4 degrees Celsius 1.0 M Sodium phosphate dibasic dihydrate will crystallize out of solution. If this happens, warm the reagent at 37 degrees until complete solubility is observed (4 to 8 hours) and then store the reagent between 4 and 25 degrees Celsius.

1.0 M 磷酸氢二钠二水合物在 4 摄氏度和更高温度下完全溶于水。低于 4 摄氏度 1.0 M 磷酸氢二钠二水合物将从溶液中结晶出来。如果发生这种情况，请将试剂加热到 37 度，直到观察到完全溶解（4 到 8 小时），然后将试剂储存在 4 到 25 摄氏度之间。

参考Sodium phosphate dibasic dihydrate

1. Properties of a new crystal form of the complex of concanavalin A with methyl alpha-D-glucopyranoside. Yariv, J; Kalb, AJ; Papiz, MZ; Helliwell, JR; Andrews, SJ; Habash, J. J Mol Biol 195, 759- 760, 1987.

1. 伴刀豆球蛋白 A 与甲基 α-D-吡喃葡萄糖苷的复合物新晶型的性质。亚里夫，J；卡尔布，AJ；帕皮兹，MZ；海利韦尔，JR；安德鲁斯，SJ； Habash, J. J Mol Biol 195, 759-760, 1987。

Hampton蛋白结晶试剂盒Sodium phosphate monobasic monohydrate/HR2-551

Products > Optimize Reagents > Optimize – Salts > Sodium phosphate monobasic monohydrate

Sodium phosphate monobasic monohydrate

CAT NO

HR2-551

NAME

4.0 M Sodium phosphate monobasic monohydrate

DESCRIPTION

200 mL

PRICE

$125.00

支持材料

HR2-551 Sodium phosphate monobasic monohydrate SDS

Sodium potassium phosphate dilution table

应用

Crystallization grade Sodium phosphate monobasic monohydrate for formulating screens or for optimization
结晶级磷酸二氢钠一水合物，用于配制筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium phosphate monobasic monohydrate

Synonyms: Monosodium phosphate or Sodium dihydrogen phosphate monohydrate
NaH₂PO₄ • H₂O
H₂NaO₄P • H₂O
M_r 137.99
CAS Number [10049-21-5]
EC Number 231-449-2
Merck 14,8660
MDL Number MFCD00149208
PubChem Substance ID 24886208
Purity ≥ 99.0%
pKa 6.8 – 7.2 (depending on the physicochemical characteristics during pKa determination)
pKa 7.2 at 20°C

Measured pH range: 3.4 – 3.5 at 25°C
Measured Conductivity Range: 58.8 – 60.5 mS/cm at 25°C
Measured Refractive Index Range: 1.38208 – 1.38243 at 20°C

别名：磷酸一钠或磷酸二氢钠一水合物
NaH2PO4 • H2O
H2NaO4P • H2O
137.99 先生
CAS 编号 [10049-21-5]
欧盟编号 231-449-2
默克 14,8660
MDL 编号 MFCD00149208
PubChem 物质 ID 24886208
纯度≥99.0%
pKa 6.8 – 7.2（取决于 pKa 测定过程中的物理化学特性）
pKa 7.2 在 20°C

测得的 pH 值范围：25°C 时 3.4 – 3.5
测得的电导率范围：25°C 时 58.8 – 60.5 mS/cm
测得的折射率范围：20°C 时为 1.38208 – 1.38243

As ≤0.00005%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.0005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.005%
Mg ≤0.0005%
Mn ≤0.0005%
N ≤0.001%
Ni ≤0.0005%
Pb ≤0.0005%
SO₄ ≤0.003%
Zn ≤0.0005%

Hampton蛋白结晶试剂盒Sodium potassium phosphate (Quik Optimize)/HR2-223

Products > Optimize Reagents > Optimize – Salts > Sodium potassium phosphate (Quik Optimize)

Sodium potassium phosphate (Quik Optimize)

CAT NO

HR2-223

NAME

Quik Optimize

DESCRIPTION

100 mL each

PRICE

$240.00

支持材料

HR2-223 Quik Optimize Documents

HR2-223 Quik Optimize SDS

HR2-223 Quik Optimize Dilution Table

应用

Optimization of Sodium potassium phosphate concentration and pH
优化磷酸钠钾浓度和pH

特征

Sterile filtered solution
Supplied formulation guide allows for quick and simple pH and dilution grids
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
提供的配方指南允许快速和简单的 pH 值和稀释网格
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述

The Quik Optimize reagent set is designed to deliver a flexible phosphate reagent based solubility and crystallization screening method for the crystallization of biological macromolecules. Quick Optimize allows convenient and simple reproduction of original Quik Screen conditions. The kit is especially useful for refinement and optimization of preliminary successful crystallization conditions determined using Quik Screen.

Quik Optimize is composed of two high purity, sterile filtered stock solutions, 4.0 M Sodium phosphate monobasic monohydrate (NaH₂PO₄ M_r 137.99 CAS Number [10049-21-5]) and 4.0 M Potassium phosphate dibasic (K₂HPO₄ M_r 174.18 CAS Number [7758-11-4]) formulated using ultra pure water. Final reagent pH is determined by the ratio of Sodium and Potassium phosphate reagents. The supplied dilution table makes concentration and pH determinations quick and simple. Reagent concentrations between 0.2 and 4.0 M in 0.2 M increments and pH values between 5.0 and 8.2 in 0.2 pH increments can be conveniently formulated with Quik Optimize.

The Quik Optimize formulation has been used successfully in both crystallographic and bioseparation applications for the crystallization of biological macromolecules 1-7. The phosphate reagent system in Quik Optimize is a stable, flexible, easy to reproduce, cost-effective, and simple way to screen and optimize crystallization conditions for biological macromolecules. Quik Optimize was developed by Macrocrystal Oy and is manufactured and distributed exclusively by Hampton Research.

Each Quik Optimize kit contains 4.0 M Sodium phosphate monobasic monohydrate and 4.0 M Potassium phosphate dibasic reagents, 100 ml each. These ready to use reagents are formulated using high purity salts with ultra pure water and are sterile filtered. Each kit contains a dilution table to create any pH (between 5.0 & 8.2) and any concentration (between 0.2 & 4.0 M) in 0.2 increments. Crystallization accessories are sold separately.

Quik Optimize 试剂套装旨在提供灵活的基于磷酸盐试剂的溶解度和结晶筛选方法，用于生物大分子的结晶。快速优化可以方便、简单地再现原始 Quik 屏幕条件。该试剂盒特别适用于改进和优化使用 Quik Screen 确定的初步成功结晶条件。

Quik Optimize 由两种高纯度、无菌过滤储备溶液组成：4.0 M 磷酸二氢钠一水合物（NaH2PO4 Mr 137.99 CAS 编号 [10049-21-5]）和 4.0 M 磷酸氢二钾（K2HPO4 Mr 174.18 CAS 编号 [7758-11] -4]) 使用超纯水配制。最终试剂的 pH 值由磷酸钠和磷酸钾试剂的比例决定。提供的稀释表使浓度和 pH 值的测定快速而简单。使用 Quik Optimize 可以方便地配制 0.2 和 4.0 M 之间的 0.2 M 增量的试剂浓度和 5.0 和 8.2 之间的 0.2 pH 增量的 pH 值。

Quik Optimize 配方已成功用于生物大分子 1-7 结晶的晶体学和生物分离应用。 Quik Optimize 中的磷酸盐试剂系统是一种用于筛选和优化生物大分子结晶条件的稳定、灵活、易于复制、经济高效且简单的方法。 Quik Optimize 由 Macrocrystal Oy 开发，由 Hampton Research 独家制造和分销。

每个 Quik Optimize 试剂盒包含 4.0 M 磷酸二氢钠一水合物和 4.0 M 磷酸氢二钾试剂，各 100 ml。这些即用型试剂使用高纯度盐和超纯水配制而成，并经过无菌过滤。每个试剂盒都包含一个稀释表，以 0.2 为增量创建任何 pH 值（5.0 和 8.2 之间）和任何浓度（0.2 和 4.0 M 之间）。结晶配件单独出售。

参考Sodium phosphate monobasic monohydrate

1. Matthews, B.W., et al., J. Mol. Bio. (1979) 130, 507-510.

2. Blow, D.M., Acta Cryst. (1958) 11, 125-126.

3. Perutz, M.F., et al., J. Mol. Bio. (1968) 33, 283-297.

4. Kretsinger, R.H., J. Mol. Bio. (1968) 38, 141-143.

5. Johnson, J.E., et al., J. Ultrastruc. Res. (1977) 61, 240-242.

6. Davies, D.R., et al., Proc. Natl. Acad. Sci. USA (1972) 69, 3689-3992

7. Stout, C.D., J. Biol. Chem. (1979) 254, 3598-3599.

Hampton蛋白结晶试剂盒Sodium sulfate decahydrate/HR2-673

Products > Optimize Reagents > Optimize – Salts > Sodium sulfate decahydrate

Sodium sulfate decahydrate

CAT NO

HR2-673

NAME

1.0 M Sodium sulfate decahydrate

DESCRIPTION

200 mL

PRICE

$104.00

支持材料

HR2-673 Sodium sulfate decahydrate SDS

应用

Crystallization grade Sodium sulfate decahydrate for formulating screens or for optimization
结晶级十水硫酸钠，用于配制筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium sulfate decahydrate

Synonyms: Glauber’s salt
Na₂SO₄• 10H₂O
Na₂O₄S • 10H₂O
M_r 322.20
CAS Number [7727-73-3]
EC Number 231-820-9
MDL Number MFCD00149189
PubChem Substance ID 24886332
Purity ≥ 99.0%

Measured pH range: 5.9 – 6.6 at 25°C
Measured Conductivity Range: 92.8 – 95.0 mS/cm at 25°C
Measured Refractive Index Range: 1.35158 – 1.35196 at 20°C

别名：芒硝
Na2SO4 • 10H2O
Na2O4S • 10H2O
322.20 先生
CAS 编号 [7727-73-3]
欧盟编号 231-820-9
MDL 编号 MFCD00149189
PubChem 物质 ID 24886332
纯度≥99.0%

测得的 pH 值范围：25°C 时 5.9 – 6.6
测得的电导率范围：25°C 时 92.8 – 95.0 mS/cm
测得的折射率范围：20°C 时为 1.35158 – 1.35196

Ca ≤0.002%
Cd ≤0.0005%
Cl ≤0.0005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.002%
Mg ≤0.0005%
Mn ≤0.0005%
Ni ≤0.0005%
Pb ≤0.0005%
PO₄ ≤0.001%
Zn ≤0.0005%

参考Sodium sulfate decahydrate

1. Crystallization and preliminary X-ray analysis of brazzein, a new sweet protein. Ishikawa, K; Ota, M; Ariyoshi, Y; Sasaki, H; Tanokura, M; Ming, D; Caldwell, J; Abildgaad, F. Acta Crystallogr D 52, 577- 578, 1996.

1. 一种新的甜蛋白 brazzein 的结晶和初步 X 射线分析。石川，K；太田，M；有吉，Y；佐佐木，H；田仓，M；明，D；考德威尔，J； Abildgaad, F. Acta Crystallogr D 52, 577-578, 1996。

Hampton蛋白结晶试剂盒Sodium tartrate dibasic dihydrate/HR2-677

Products > Optimize Reagents > Optimize – Salts > Sodium tartrate dibasic dihydrate

Sodium tartrate dibasic dihydrate

CAT NO

HR2-677

NAME

1.5 M Sodium tartrate dibasic dihydrate

DESCRIPTION

200 mL

PRICE

$117.00

支持材料

HR2-677 Sodium tartrate dibasic dihydrate SDS

应用

Crystallization grade reagents for formulating screens or for optimization
用于配制筛选或优化的结晶级试剂

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium tartrate dibasic dihydrate

Synonyms: L-(+)-Tartaric acid disodium salt or Disodium tartrate dihydrate or Sodium tartrate dihydrate
C₄H₄Na₂O₆ • 2H₂O
M_r 230.08
CAS [6106-24-7]
EC Number 212-773-3
Merck 14,8684
Beilstein Registry Number 6121732
MDL Number MFCD00150035
PubChem Substance ID 24899620
Purity ≥ 99.0%

Measured pH range: 7.5 – 8.8 at 25°C
Measured Conductivity Range: 67.9 – 71.4 mS/cm at 25°C
Measured Refractive Index Range: 1.37544 – 1.37625 at 20°C

别名：L-(+)-酒石酸二钠盐或酒石酸二钠二水合物或酒石酸钠二水合物
C4H4Na2O6 • 2H2O
230.08 先生
CAS [6106-24-7]
欧盟编号 212-773-3
默克 14,8684
贝尔斯坦注册号 6121732
MDL 编号 MFCD00150035
PubChem 物质 ID 24899620
纯度≥99.0%

测得的 pH 值范围：25°C 时 7.5 – 8.8
测得的电导率范围：25°C 时为 67.9 – 71.4 mS/cm
测得的折射率范围：20°C 时为 1.37544 – 1.37625

Total Impurities ≤0.005% insoluble matter passes filter test
Al ≤0.0005%
As ≤0.00001%
Ba ≤0.0005%
Bi ≤0.0005%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.0005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.005%
Li ≤0.0005%
Mg ≤0.0005%
Mn ≤0.0005%
Mo ≤0.0005%
Ni ≤0.0005%
Pb ≤0.0005%
PO₄ ≤0.0005%
SO₄ ≤0.005%
Sr ≤0.0005%
Zn ≤0.0005%

Sodium tartrate dibasic dihydrate

Hampton蛋白结晶试剂盒Sodium thiocyanate/HR2-693

Products > Optimize Reagents > Optimize – Salts > Sodium thiocyanate

Sodium thiocyanate

CAT NO

HR2-693

NAME

8.0 M Sodium thiocyanate

DESCRIPTION

200 mL

PRICE

$104.00

支持材料

HR2-693 Sodium thiocyanate SDS

应用

Crystallization grade Sodium thiocyanate for formulating screens or for optimization
结晶级硫氰酸钠，用于配制屏幕或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Sodium thiocyanate

Synonyms: Sodium isothiocyanate or Sodium rhodanate or Sodium rhodanide or Sodium sulfocyanate
NaSCN
CNNaS
M_r 81.07
CAS Number [540-72-7]
EC Number 208-754-4
Beilstein Registry Number 3594965
MDL Number MFCD00011123
Purity ≥ 98.0%

Measured pH range: 6.8 – 9.5 at 25°C
Measured Conductivity Range: 158.6 – 170.2 mS/cm at 25°C
Measured Refractive Index Range: 1.45613 – 1.46117 at 20°C

别名：异硫氰酸钠或硫氰酸钠或硫氰酸钠或硫氰酸钠
钠SCN
CNNaS
81.07 先生
CAS 编号 [540-72-7]
欧盟编号 208-754-4
贝尔斯坦注册号 3594965
MDL 编号 MFCD00011123
纯度≥98.0%

测得的 pH 值范围：25°C 时为 6.8 – 9.5
测得的电导率范围：25°C 时为 158.6 – 170.2 mS/cm
测得的折射率范围：20°C 时为 1.45613 – 1.46117

Ca ≤0.02%
Cd ≤0.005%
Cl ≤0.05%
Co ≤0.005%
Cu ≤0.005%
Fe ≤0.005%
K ≤0.2%
Ni ≤0.005%
Pb ≤0.005%
SO₄ ≤0.05%
Zn ≤0.005%

Sodium thiocyanate

参考

1. A Toxin that recognizes muscarinic acetylcholine receptors Preparation and characterization of crystals suitable for structural analysis. Menez, R; Ducruix, A. J Mol Biol 232, 997- 998, 1993.

1. 一种识别毒蕈碱乙酰胆碱受体的毒素适合结构分析的晶体的制备和表征。梅内斯，R； Ducruix, A. J Mol Biol 232, 997-998, 1993。

Hampton蛋白结晶试剂盒Succinic acid pH 7.0/HR2-709

Products > Optimize Reagents > Optimize – Salts > Succinic acid pH 7.0

Succinic acid pH 7.0

CAT NO

HR2-709

NAME

1.2 M Succinic acid pH 7.0

DESCRIPTION

200 mL

PRICE

$127.00

支持材料

HR2-709 Succinic acid pH 7.0 SDS

应用

Crystallization grade Succinic acid pH 7 for formulating screens or for optimization
结晶级琥珀酸 pH 7，用于配制筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Succinic acid pH 7.0

Synonym: Dicarboxylic acid C4 or Butanedioic acid
C₄H₆O₄
HOOCCH₂CH₂COOH
M_r 118.09
CAS Number [110-15-6]
EC Number 203-740-4
Beilstein Registry Number 1754069
RTECS WM4900000
MDL Number MFCD00002789
PubChem Substance ID 24848479
Merck 14,8869
Purity ≥ 99.5%
pKa1 = 4.2
pKa2 = 5.6

HR2-709 is titrated to pH 7.0 using NaOH
Measured Conductivity Range: 70.1 – 80.2 mS/cm at 25°C
Measured Refractive Index Range: 1.36344 – 1.36407 at 20°C

别名：二羧酸C4或丁二酸
C4H6O4
HOOCCH2CH2COOH
118.09 先生
CAS 编号 [110-15-6]
欧盟编号 203-740-4
贝尔斯坦注册号 1754069
RTECS WM4900000
MDL 编号 MFCD00002789
PubChem 物质 ID 24848479
默克 14,8869
纯度≥99.5%
pKa1 = 4.2
pKa2 = 5.6

使用 NaOH 将 HR2-709 滴定至 pH 7.0
测得的电导率范围：25°C 时 70.1 – 80.2 mS/cm
测得的折射率范围：20°C 时为 1.36344 – 1.36407

Ca ≤0.005%
Cd ≤0.0005%
Cl ≤0.001%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.005%
Mg ≤0.001%
Mn ≤0.0005%
N ≤0.001%
Na ≤0.0005%
Ni ≤0.0005%
Pb ≤0.0005%
PO₄ ≤0.001%
SO₄ ≤0.003%
Zn ≤0.0005%

参考Succinic acid

1. A comparison of salts for the crystallization of macromolecules. Alexander McPherson. Protein Science (2001), 10:418-422.

200 mL

PRICE

$120.00

支持材料

What is Tacsimate?

Mixing Tacsimate Stocks to Screen Ph

HR2-823 Tacsimate 100% solution pH 4.0 SDS

HR2-825 Tacsimate 100% solution pH 5.0 SDS

HR2-827 Tacsimate 100% solution pH 6.0 SDS

HR2-755 Tacsimate 100% solution pH 7.0 SDS

HR2-829 Tacsimate 100% solution pH 8.0 SDS

HR2-813 Tacsimate 100% solution pH 9.0 SDS

应用

Crystallization grade Tacsimate for formulating screens or for optimization
结晶级 Tacsimate 用于配制屏幕或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述

To screen pH as a crystallization variable using Tacsimate one can mix together different ratios of different pH Tacsimate solutions. Refer to the pdf “Mixing Tacsimate Stocks to Screen pH” on this page. Or, one can add a buffer to the crystallizaiton reagent containing Tacsimate. Recommended final buffer concentration in the reagent well is 0.05 to 0.1 M.

Tacsimate
A pH titrated mixture of organic acids. 1.8305 M Malonic acid, 0.25 M Ammonium citrate tribasic, 0.12 M Succinic acid, 0.3 M DL-Malic acid, 0.4 M Sodium acetate trihydrate, 0.5 M Sodium formate, 0.16 M Ammonium tartrate dibasic. pH adjusted using NaOH

Measured pH of 100% Tacsimate is 4.0 at 25°C
Measured pH of 100% Tacsimate is 5.0 at 25°C
Measured pH of 100% Tacsimate is 6.0 at 25°C
Measured pH of 100% Tacsimate is 7.0 at 25°C
Measured pH of 100% Tacsimate is 8.0 at 25°C
Measured pH of 100% Tacsimate is 9.0 at 25°C

为了使用 Tacsimate 将 pH 值筛选为结晶变量，可以将不同比例的不同 pH 值的 Tacsimate 溶液混合在一起。请参阅本页上的 pdf“混合 Tacsimate 库存以筛选 pH 值”。或者，可以将缓冲液添加到含有 Tacsimate 的结晶试剂中。试剂孔中推荐的最终缓冲液浓度为 0.05 至 0.1 M。

战术
pH 值滴定的有机酸混合物。 1.8305 M 丙二酸、0.25 M 柠檬酸三铵、0.12 M 琥珀酸、0.3 M DL-苹果酸、0.4 M 三水乙酸钠、0.5 M 甲酸钠、0.16 M 酒石酸氢铵。使用 NaOH 调节 pH

在 25°C 时测得的 100% Tacsimate 的 pH 值为 4.0
在 25°C 时测得的 100% Tacsimate 的 pH 值为 5.0
在 25°C 时测得的 100% Tacsimate 的 pH 值为 6.0
在 25°C 时测得的 100% Tacsimate 的 pH 值为 7.0
在 25°C 时测得的 100% Tacsimate 的 pH 值为 8.0
在 25°C 时测得的 100% Tacsimate 的 pH 值为 9.0

Mixture of organic acids. Malonic acid, Ammonium citrate tribasic, Succinic acid, DL-Malic acid, Sodium acetate trihydrate, Sodium formate, and Ammonium tartrate dibasic

有机酸的混合物。丙二酸、柠檬酸三铵、琥珀酸、DL-苹果酸、醋酸钠三水合物、甲酸钠和酒石酸氢铵

参考

1. Searching for silver bullets: An alternative strategy for crystallizing macromolecules. Alexander McPherson and Bob Cudney. Journal of Structural Biology 156 (2006) 387–406.

2. A novel strategy for the crystallization of proteins: X-ray diffraction validation. Steven B. Larson, John S. Day, Robert Cudney and Alexander McPherson. Acta Cryst. (2007). D63, 310–318.

3. Structure of the catalytic and ubiquitin-associated domains of the protein kinase MARK/Par-1. Eckhard Mandelkow et al. Structure 14, 173-183, February 2006.

4. A comparison of salts for the crystallization of macromolecules. Alexander McPherson. Protein Science (2001), 10:418-422.

5. Crystallization of a newly discovered histidine acid phosphatase from Francisella tularensis. Richard L. Felts, Thomas J. Reilly, Michael J. Calcutt, and John J. Tanner. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 January 1; 62(Pt 1): 32–35.

6. Structure of the GTPase and GDI domains of FeoB, the ferrous iron transporter of Legionella pneumophila. Petermann et al, FEBS Letters Volume 584, Issue 4, Pages 733-738 (19 February 2010).

1. 寻找灵丹妙药：结晶大分子的另一种策略。亚历山大·麦克弗森和鲍勃·库德尼。结构生物学杂志 156 (2006) 387–406。

2. 蛋白质结晶的新策略：X 射线衍射验证。 Steven B. Larson、John S. Day、Robert Cudney 和 Alexander McPherson。晶体学报。（2007 年）。 D63，310-318。

3. 蛋白激酶 MARK/Par-1 的催化和泛素相关结构域的结构。 Eckhard Mandelkow 等人。结构 14, 173-183，2006 年 2 月。

4. 大分子结晶盐的比较。亚历山大·麦克弗森。蛋白质科学（2001），10：418-422。

5. 从土拉弗朗西斯菌中新发现的组氨酸酸性磷酸酶的结晶。 Richard L. Felts、Thomas J. Reilly、Michael J. Calcutt 和 John J. Tanner。 Acta Crystallogr Sect F Struct Biol Cryst Commun。 2006 年 1 月 1 日； 62（第 1 篇）：32-35。

6. 嗜肺军团菌的亚铁转运体 FeoB 的 GTPase 和 GDI 结构域。 Petermann 等人，FEBS Letters 第 584 卷，第 4 期，第 733-738 页（2010 年 2 月 19 日）。

Hampton蛋白结晶试剂盒Trimethylamine N-oxide dihydrate/HR2-777

Products > Optimize Reagents > Optimize – Salts > Trimethylamine N-oxide dihydrate

Trimethylamine N-oxide dihydrate

CAT NO

HR2-777

NAME

1.0 M Trimethylamine N-oxide dihydrate

DESCRIPTION

100 mL

PRICE

$130.00

支持材料

HR2-777 Trimethylamine N-oxide dihydrate SDS

应用

Crystallization grade Trimethylamine N-oxide dihydrate for formulating screens or for optimization
结晶级三甲胺 N-氧化物二水合物，用于配制筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Trimethylamine N-oxide dihydrate

Synonym: TMANO
(CH₃)₃NO • 2H₂O
C₃H₉NO • 2H₂O
M_r 111.14
CAS Number [62637-93-8]
EC Number 214-675-6
Beilstein Registry Number 4(4)144
Merck 14,9711
RTECS YH2850000
MDL Number MFCD00002048
Purity > 98.0%
Maximum solubility is 6.0 M at 25°C (tested by Hampton Research)

Measured pH Range: 8.0 – 9.3 at 25°C
Measured Conductivity Range: 10.9 – 67.1 µS/cm at 25°C
Measured Refractive Index Range: 1.34320 – 1.34348 at 20°C

同义词： TMANO
(CH3)3NO • 2H2O
C3H9NO • 2H2O
111.14 先生
CAS 编号 [62637-93-8]
欧盟编号 214-675-6
贝尔斯坦注册号 4(4)144
默克 14,9711
RTECS YH2850000
MDL 编号 MFCD00002048
纯度 > 98.0%
25°C 时最大溶解度为 6.0 M（由 Hampton Research 测试）

测得的 pH 范围：25°C 时 8.0 – 9.3
测得的电导率范围：25°C 时为 10.9 – 67.1 µS/cm
测得的折射率范围：20°C 时为 1.34320 – 1.34348

Trimethylamine N-oxide dihydrate

参考

1. Use of organic cosmotropic solutes to crystallize flexible proteins: Application to T7 RNA polymerase and its complex with the inhibitor T7 lysozyme. Jeruzalmi and Steitz, J. Mol. Bio. (1997) 274, 748-756.

2. Trimethylamine N-oxide as a versatile cryoprotective agent in macromolecular crystallography. Mueller-Dieckmann, C., Kauffmann, B., and Weiss, M. J. Appl. Cryst. (2011). 44, 433–436.

3. Crystallization of a functionally intact Hsc70 chaperone. J. Jiang, E. M. Lafer and R. Sousa. Acta Cryst. (2006). F62, 39-43.

4. Doolittle, R. F. (2003). Biophys. Chem. 100, 307–313.

5. Hill, M. C., Bates, I. R., White, G. F., Hallett, F. R. & Harauz, G. (2002). J.

6. Auton, M. & Bolen, D. W. (2005). Proc. Natl Acad. Sci. USA, 102, 15065–15068.

7. Bolen, D. W. (2004). Methods, 34, 312–322.

Hampton蛋白结晶试剂盒Tryptone/HR2-835

Products > Optimize Reagents > Optimize – Salts > Tryptone

Tryptone

CAT NO

HR2-835

NAME

10% w/v Tryptone

DESCRIPTION

100 mL

PRICE

$94.00

支持材料

HR2-835 10% w/v Tryptone SDS

应用

Crystallization grade Tryptone for formulating screens or for optimization
用于配制筛选或优化的结晶级胰蛋白胨

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Tryptone

Synonyms: Peptone from casein
Microbiologically tested
CAS Number [91079-40-2]
EC Number: 293-428-4

Measured pH Range: 6.9 – 7.1 at 25°C
Measured Conductivity Range: 7.5 – 11.1 mS/cm at 25°C
Measured Refractive Index Range: 1.35040 – 1.35133 at 20°C

Tryptone is the assortment of peptides formed by the digestion of casein by the protease trypsin. Tryptone is rich in tryptophan. There are no detectable levels of carbohydrates in Tryptone. The enzymatic digest is pasteurized and spray dried prior to formulation in Type 1 laboratory water and sterile filtered (0.22 micron filter).

同义词：酪蛋白蛋白胨
微生物测试
CAS 编号 [91079-40-2]
欧盟编号：293-428-4

测得的 pH 值范围：25°C 时为 6.9 – 7.1
测得的电导率范围：25°C 时 7.5 – 11.1 mS/cm
测得的折射率范围：20°C 时为 1.35040 – 1.35133

胰蛋白胨是由蛋白酶胰蛋白酶消化酪蛋白形成的肽组合。色氨酸富含色氨酸。胰蛋白胨中没有可检测到的碳水化合物水平。酶消化物经过巴氏杀菌和喷雾干燥，然后在 1 型实验室用水中进行配制并无菌过滤（0.22 微米过滤器）。

参考Tryptone

1. Progress in the Development of an Alternative Approach to Macromolecular Crystallization. S. B. Larson,J. S. Day, C. Nguyen, R. Cudney, and A. McPherson. Crystal Growth & Design 2008 Volume 8, No. 8 3038-3052.

1. 大分子结晶替代方法的开发进展。 S. B.拉尔森，J. S. Day、C. Nguyen、R. Cudney 和 A. McPherson。晶体生长与设计 2008 年第 8 卷，第 8 期 3038-3052。

Hampton蛋白结晶试剂盒Zinc acetate dihydrate/HR2-563

Products > Optimize Reagents > Optimize – Salts > Zinc acetate dihydrate

Zinc acetate dihydrate

CAT NO

HR2-563

NAME

1.0 M Zinc acetate dihydrate

DESCRIPTION

100 mL

PRICE

$102.00

支持材料

HR2-563 Zinc acetate dihydrate SDS

应用

Crystallization grade Zinc acetate dihydrate for formulating screens or for optimization
结晶级醋酸锌二水合物，用于配制屏幕或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Zinc acetate dihydrate

Synonyms: Zinc acetate
Zn(CH₃COO)₂• 2H₂O
C₄H₆O₄Zn • 2H₂O
M_r 219.52
CAS Number [5970-45-6]
EC Number 209-170-2
Beilstein Registry Number 3732513
Merck 14,10128
RTECS ZG8750000
UN Number 3077 9/PG 3
MDL Number MFCD00066961
PubChem Substance ID 24890299
Purity ≥ 99.0%

Measured pH range: 5.7 – 5.8 at 25°C
Measured Conductivity Range: 17.3 – 17.9 mS/cm at 25°C
Measured Refractive Index Range: 1.35728 – 1.35741 at 20°C

别名：醋酸锌
Zn(CH3COO)2 • 2H2O
C4H6O4Zn • 2H2O
219.52 先生
CAS 编号 [5970-45-6]
欧盟编号 209-170-2
贝尔斯坦注册号 3732513
默克 14,10128
RTECS ZG8750000
联合国编号 3077 9/PG 3
MDL 编号 MFCD00066961
PubChem 物质 ID 24890299
纯度≥99.0%

测得的 pH 值范围：25°C 时为 5.7 – 5.8
测得的电导率范围：25°C 时 17.3 – 17.9 mS/cm
测得的折射率范围：20°C 时为 1.35728 – 1.35741

As ≤0.00001%
Ca ≤0.001%
Cd ≤0.0005%
Cl ≤0.0005%
Co ≤0.0005%
Cr ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.005%
Mg ≤0.0005%
Mn ≤0.0005%
N ≤0.002%
Na ≤0.005%
Ni ≤0.0005%
Pb ≤0.0005%
SO₄ ≤0.005%

参考 Zinc acetate dihydrate

1. A new crystal form of carboxypeptidase G from Pseudomonas sp. strain RS-16 which is more amenable to structure determination. Tucker, AD; Rowsell, S; Melton, RG; Pauptit, RA. Acta Crystallogr D 52, 890- 892, 1996.

1. 一种来自假单胞菌属的羧肽酶 G 的新晶型。应变 RS-16 更适合结构测定。塔克，广告；罗塞尔，S；梅尔顿，RG；帕普蒂特，RA。晶体学学报 D 52, 890-892, 1996。

Hampton蛋白结晶试剂盒Zinc chloride/HR2-811

Products > Optimize Reagents > Optimize – Salts > Zinc chloride

Zinc chloride

CAT NO

HR2-811

NAME

2.0 M Zinc chloride

DESCRIPTION

100 mL

PRICE

$77.00

Support Material(s)

HR2-811 Zinc chloride SDS

应用

Crystallization grade Zinc chloride for formulating screens or for optimization
结晶级氯化锌，用于筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Zinc chloride

Synonyms: Zinc chloride anhydrous
ZnCl₂
Cl₂Zn
M_r 136.30
CAS [7646-85-7]
EC Number 231-592-0
Merck 14,10132
Beilstein Registry Number 3732513
RTECS ZH1400000
UN Number 2331 8/PG 3
MDL Number MFCD00011295
Melting Point (Starting Material) 293°C (lit.)

Measured pH Range: 3.1 – 4.1 at 25°C
Measured Conductivity Range: 90.2 – 104.3 mS/cm at 25°C
Measured Refractive Index Range: 1.37536 – 1.37646 at 20°C

别名：无水氯化锌
氯化锌
氯化锌
136.30 先生
CAS [7646-85-7]
欧盟编号 231-592-0
默克 14,10132
贝尔斯坦注册号 3732513
RTECS ZH1400000
联合国编号 2331 8/PG 3
MDL 编号 MFCD00011295
熔点（起始材料）293°C（点燃）

测得的 pH 范围：25°C 时 3.1 – 4.1
测得的电导率范围：25°C 时 90.2 – 104.3 mS/cm
测得的折射率范围：20°C 时为 1.37536 – 1.37646

Ca ≤0.001%
Cd ≤0.0005%
Cu ≤0.001%
Fe ≤0.0005%
K ≤0.001%
Mg ≤0.001%
N ≤0.002%
Na ≤0.001%
Pb ≤0.001%
SO₄ ≤0.002%
ZnO ≤1.2%

Zinc chloride

Hampton蛋白结晶试剂盒Zinc sulfate heptahydrate/HR2-641

Products > Optimize Reagents > Optimize – Salts > Zinc sulfate heptahydrate

Zinc sulfate heptahydrate

CAT NO

HR2-641

NAME

2.0 M Zinc sulfate heptahydrate

DESCRIPTION

100 mL

PRICE

$92.00

支持材料

HR2-641 Zinc sulfate heptahydrate SDS

应用

Crystallization grade Zinc sulfate heptahydrate for formulating screens or for optimization
结晶级七水硫酸锌，用于筛选或优化

特征

Sterile filtered solution
Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL)
无菌过滤溶液
在 1+ 型超纯水中配制：25°C 时电阻率为 18.2 兆欧厘米，总有机碳 < 5 ppb，无细菌（<1 细菌 (CFU/ml)），无热原（<0.03 内毒素 (EU/ml)） , 无 RNase (< 0.01 ng/mL) 和无 DNase (< 4 pg/µL)

描述Zinc sulfate heptahydrate

Synonyms: None
ZnSO₄• 7H₂O
M_r 287.56 (161.46 without water)
CAS Number [7446-20-0]
EC Number 231-793-3
RTECS ZH5300000
Merck 14,10159
MDL Number MFCD00149894
PubChem Substance ID 24859031
Purity ≥ 99.5%
UN Number UN 3077 9/PG 3

Measured pH range: 3.4 – 4.4 at 25°C
Measured Conductivity Range: 54.1 – 57.6 mS/cm at 25°C
Measured Refractive Index Range: 1.38196 – 1.38598 at 20°C

同义词：无
ZnSO4 • 7H2O
287.56先生（161.46无水）
CAS 编号 [7446-20-0]
欧盟编号 231-793-3
RTECS ZH5300000
默克 14,10159
MDL 编号 MFCD00149894
PubChem 物质 ID 24859031
纯度≥99.5%
联合国编号 UN 3077 9/PG 3

测得的 pH 值范围：25°C 时为 3.4 – 4.4
测得的电导率范围：25°C 时 54.1 – 57.6 mS/cm
测得的折射率范围：20°C 时为 1.38196 – 1.38598

As ≤0.00005%
Ca ≤0.001%
Cd ≤0.0002%
Cl ≤0.0005%
Cu ≤0.0005%
Fe ≤0.0005%
K ≤0.001%
Mg ≤0.001%
Mn ≤0.0002%
N ≤0.0005%
Na ≤0.0005%
Pb ≤0.0005%

Zinc sulfate heptahydrate

参考

1. Crystallization and preliminary X-ray diffraction studies of psoriasin. Nolsoe, S; Thirup, S; Etzerodt, M; Thogersen, HC; Nyborg, J. Acta Crystallogr D 53, 119- 121, 1997.

1. 牛皮癣的结晶和初步 X 射线衍射研究。诺尔索，S；蒂鲁普，S；埃泽罗特，M；托格森，HC； Nyborg, J. Acta Crystallogr D 53, 119-121, 1997。

Sodium formate

CAT NO

NAME

DESCRIPTION

PRICE

CAT NO

NAME

DESCRIPTION

PRICE

支持材料

应用

特征

描述Sodium formate

参考Sodium formate

Sodium malonate

CAT NO

NAME

DESCRIPTION

PRICE

CAT NO

NAME

DESCRIPTION

PRICE

CAT NO

NAME

DESCRIPTION

PRICE

CAT NO

NAME

DESCRIPTION

PRICE

CAT NO

NAME

DESCRIPTION

PRICE

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应用

特征

描述

参考Sodium malonate

Sodium nitrate

CAT NO

NAME

DESCRIPTION

PRICE

支持材料

应用

特征

描述Sodium nitrate

参考Sodium nitrate

Sodium phosphate dibasic dihydrate

CAT NO

NAME

DESCRIPTION

PRICE

支持材料

应用

特征

描述Sodium phosphate dibasic dihydrate

参考Sodium phosphate dibasic dihydrate

Sodium phosphate monobasic monohydrate

CAT NO

NAME

DESCRIPTION

PRICE

支持材料

应用

特征

描述Sodium phosphate monobasic monohydrate

相关项目Sodium phosphate monobasic monohydrate

Sodium potassium phosphate (Quik Optimize)

CAT NO

NAME

DESCRIPTION

PRICE

支持材料

相关项目

应用

特征

描述