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- Sulfo-Cyanine5.5 maleimide
Sulfo-Cyanine5.5 maleimide
| 货号 | 规格 | 价格 | 货期 |
|---|---|---|---|
| 17380 | 1 mg | 110.00$ | in stock |
| 27380 | 5 mg | 290.00$ | in stock |
| 47380 | 25 mg | 690.00$ | in stock |
| 57380 | 50 mg | 1270.00$ | in stock |
| 67380 | 100 mg | 1990.00$ | in stock |
Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.
This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.
Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料，由于存在四个磺基，因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。
这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案，应使用适当的还原剂（例如 TCEP）还原天然蛋白质的二硫键。
Absorption and emission spectra of sulfo-Cyanine5.5
Sulfo-Cyanine5.5 maleimide相关产品
Sulfo-Cyanine7 NHS ester
Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.
Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。
BDP TMR maleimide
A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.
用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定，以及其他应用。
Sulfo-Cyanine5 maleimide
Thiol reactive, water soluble cyanine dye for Cy5® channel.
用于 Cy5® 的硫醇活性水溶性花青染料 渠道。
General properties
| Appearance: | dark colored solid 深色固体 |
| Mass spec M+ increment: | 1024.2 |
| Molecular weight: | 1139.43 |
| CAS number: | 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt) |
| Molecular formula: | C46H45K3N4O15S4 |
| Solubility: | good in water, DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。 |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 673 |
| ε, L⋅mol−1⋅cm−1: | 211000 |
| Emission maximum, nm: | 691 |
| Fluorescence quantum yield: | 0.21 |
| CF260: | 0.09 |
| CF280: | 0.11 |
相关文献：
- Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
- Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
- Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0