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CD4 Human
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CD4 Human Recombinant
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CYT-885
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Catalogue number
CYT-885
Synonyms
CD4 Molecule, T-Cell Surface Glycoprotein CD4, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen , CD4 Receptor, CD4 Antigen, CD4mut, T-cell surface glycoprotein CD4.
Introduction
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. Normally, about 65% of T cells in the blood are CD4+ . A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
CD4 是一种细胞表面糖蛋白,存在于成熟的辅助 T 细胞和未成熟的胸腺细胞以及单核细胞和巨噬细胞上。 正常情况下,血液中约 65% 的 T 细胞是 CD4+。 具有 CD4 或 CD8 的成熟 T 细胞,但不是两者兼有。 在发育的一个阶段,T 细胞会产生 CD4 和 CD8 受体,但它们最终会在胸腺中分化并变得更加特化。 |
Description
CD4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 396 amino acids and having a molecular mass of 44kDa.
CD4 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CD4 Human Recombinant 是一条单一的、非糖基化的多肽链,含有 396 个氨基酸,分子量为 44kDa。
CD4 在 N 末端与 25 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CD4 protein solution containing 20mM Tris Hcl, PH8.0 and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMKKVVL GKKGDTVELT CTASQKKSIQ FHWKNSNQIK ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VEDQKEEVQL LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS VSQLELQDSG TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE KLTGSGELWW QAERASSSKS WITFDLKNKE VSVKRVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLA LEAKTGKLHQ EVNLVVMRAT QLQKNLTCEV WGPTSPKLML SLKLENKEAK VSKREKAVWV LNPEAGMWQC LLGQVLL ESNIKVLPTW STPVQP.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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