ProSpec,sCD40L Mouse sf9,可溶性 CD40 配体/TRAPMouse 重组体CYT-917

sCD40L Mouse, sf9
soluble CD40 Ligand/TRAPMouse Recombinant, sf9
CYT-917
1µg

5µg

25µg

Catalogue number

CYT-917

Synonyms

CD40 ligand, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, CD40lg, CD154, CD40-L, Cd40l, gp39, HIGM1, IGM, IMD3, Ly-62, Ly62, T-BAM, Tnfsf5.

Introduction

CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines . CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma , TNF-alpha , and IL2.

CD40L 或 CD154 是在 T 细胞表面表达的膜糖蛋白和分化抗原。 CD40 配体在细胞因子存在的情况下刺激 B 细胞增殖和所有免疫球蛋白同种型的分泌。 CD40 配体已显示在外周血单核细胞中诱导细胞因子产生和杀肿瘤活性。它还共同刺激活化 T 细胞的增殖，并伴随着 IFN-γ、TNF-α 和 IL2 的产生。

Description

sCD40 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17.2kDa .
sCD40 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 sCD40 Mouse Recombinant 是单条糖基化多肽链，包含 155 个氨基酸，分子量为 17.2kDa。
sCD40 在 C 末端用 6 个氨基酸 His 标签表达，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

sCD40 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.

For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。储存，在 -20°C 下冷冻更长时间。

对于长期储存，建议添加载体蛋白。

避免多次冻融循环。

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MQRGDEDPQI AAHVVSEANS NAASVLQWAK KGYYTMKSNL VMLENGKQLT VKREGLYYVY TQVTFCSNRE PSSQRPFIVG LWLKPSSGSE RILLKAANTH SSSQLCEQQS VHLGGVFELQ AGASVFVNVT EASQVIHRVG FSSFGLLKLH HHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

sCD40L Mouse, sf9