Pentynoic acid STP ester

Pentynoic acid STP ester,这种水溶性炔烃活化酯试剂用于将炔烃基团连接到各种生物分子，如蛋白质和肽。 也可以使用氨基-DNA和其他胺。 由于天然蛋白质不含炔烃，但几乎总是含有胺（赖氨酸），这种分子是将天然胺转化为炔烃的“适配器”。

  • Products
  • Click chemistry
  • Non-fluorescent alkynes
  • Pentynoic acid STP ester

Pentynoic acid STP ester

货号 规格 价格 货期
30720 10 mg 110.00$ in stock
40720 25 mg 210.00$ 5 days
50720 50 mg 410.00$ in stock
60720 100 mg 695.00$ 5 days

This water soluble alkyne activated ester reagent is used for the attachment of alkyne group to variois biomolecules such as proteins, and peptides. Amino-DNA, and other amines can be used as well. Since natural proteins do not contain alkynes, but almost always contain amines (lysines), this molecule is an “adaptor” to turn natural amines into alkynes.

Use this product to enable any of your proteins for Click Chemistry.

This is an STP (sulfotetrafluorophenyl) ester. STP esters are similar to NHS esters, but possess higher hydrophilicity, and water solubility. It works fine in pure aqueous reactions without addition of organic co-solvent, and is best suited for the modification of proteins.

这种水溶性炔烃活化酯试剂用于将炔烃基团连接到各种生物分子，如蛋白质和肽。 也可以使用氨基-DNA和其他胺。 由于天然蛋白质不含炔烃，但几乎总是含有胺（赖氨酸），这种分子是将天然胺转化为炔烃的“适配器”。

使用此产品可让您的任何蛋白质用于 Click Chemistry。

这是一种 STP（磺基四氟苯基）酯。 STP 酯与 NHS 酯相似，但具有更高的亲水性和水溶性。 它在不添加有机助溶剂的纯水反应中表现良好，最适合蛋白质的修饰。

Pentynoic acid STP ester相关产品

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

TAMRA amine, 5-isomer

TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).

TAMRA（四甲基罗丹明）染料，纯 5-异构体，带有一个胺基，可与亲电子试剂（NHS 酯、环氧化物等）结合。

Cyanine3 NHS ester minimal dye

Cyanine3 minimal dye for protein labeling.

用于蛋白质标记的 Cy3 最小染料。

General properties

Appearance: colorless solid
Mass spec M+ increment: 80.0
Molecular weight: 348.20
CAS number: 1807530-14-8
Molecular formula: C11H5F4NaO5S
IUPAC name: 4-​Pentynoic acid, 2,​3,​5,​6-​tetrafluoro-​4-​sulfophenyl ester, sodium salt
Solubility: good in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Zanon, P.R.A.; Yu, F.; Musacchio, P.; Lewald, L.; Zollo, M.; Krauskopf, K.; Mrdović, D.; Raunft, P.; Maher, T.E.; Cigler, M.; Chang, C.; Lang, K.; Toste, F.D.; Nesvizhskii, A.I.; Hacker, S.M. Profiling the proteome-wide selectivity of diverse electrophiles. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-w7rss-v2
  2. Abbasov, M.E.; Kavanagh, M.E.; Ichu, T.-A.; Lazear, M.R.; Tao, Y.; Crowley, V.M.; am Ende, C.W.; Hacker, S.M.; Ho, J.; Dix, M.M.; Suciu, R.; Hayward, M.M.; Kiessling, L.L.; Cravatt, B.F. A proteome-wide atlas of lysine-reactive chemistry. Nature Chemistry, 2021, 13(11), 1081–1092. doi: 10.1038/s41557-021-00765-4
  3. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  4. Jandl, B.; Sedghiniya, S.; Carstens, A.; Astakhova, K. Peptide–Fluorophore Hydrogel as a Signal Boosting Approach in Rapid Detection of Cancer DNA. ACS Omega, 2019, 4(9), 13889–13895. doi: 10.1021/acsomega.9b01586