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• Non-fluorescent alkynes
• Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the modification of biomolecules. Alkyne groups for copper catalyzed Click Chemistry reaction are nearly never encountered in natural molecules. However, this NHS ester allows to attach alkyne groups to amino groups, which are ubiquitous in nature, and which are present in proteins, peptides, synthetic amino-DNA and numerous small molecules. Alkyne groups can be subsequently modified and conjugated by Copper catalyzed Click chemistry.

This reagent is a derivative of hexynoic acid.

用于生物分子修饰的炔烃 NHS 酯。 用于铜催化点击化学反应的炔基在天然分子中几乎从未遇到过。 然而，这种 NHS 酯允许将炔基连接到氨基上，氨基在自然界中普遍存在，并且存在于蛋白质、肽、合成氨基 DNA 和许多小分子中。 随后可以通过铜催化的点击化学修饰和缀合炔基。

该试剂是己炔酸的衍生物。