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- Cyanine5 DBCO
Cyanine5 DBCO
| 货号 | 规格 | 价格 | 货期 |
|---|---|---|---|
| A30F0 | 1 mg | 110.00$ | in stock |
| B30F0 | 5 mg | 210.00$ | in stock |
| C30F0 | 10 mg | 310.00$ | in stock |
| D30F0 | 25 mg | 410.00$ | in stock |
| E30F0 | 50 mg | 695.00$ | in stock |
| F30F0 | 100 mg | 1190.00$ | in stock |
A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.
Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.
Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.
一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。
在不存在铜催化剂的情况下，在应变促进的炔烃叠氮化物环加成 (spAAC) 中，应变的环炔烃，例如环辛炔，与叠氮化物反应非常迅速。 该反应非常快速、温和且具有生物相容性。
与其他环炔烃相比，DBCO 提供了最快的反应动力学，但仍具有良好的稳定性。
Absorption and emission spectra of Cyanine5
Cyanine5 DBCO相关产品
Cyanine7.5 NHS ester
Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.
NIR荧光染料Cyanine7.5的胺反应性NHS酯。
Cyanine5.5 amine
Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.
Cyanine5.5 的氨基衍生物，一种发射远红色荧光的花青染料。
Sulfo-Cyanine5 tetrazine
Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.
水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。
General properties
| Appearance: | dark blue solid 深蓝色固体 |
| Mass spec M+ increment: | 928.4 |
| Molecular weight: | 929.03 |
| Molecular formula: | C53H59N4F6O2P |
| Solubility: | good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。 |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 250000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.03 |
| CF280: | 0.04 |
相关文献：
- Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
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