Sulfo-Cyanine3 tetrazine

Sulfo-Cyanine3 tetrazine,四嗪-反式-环辛烯连接是迄今为止已知最快的生物偶联反应之一。

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  • Sulfo-Cyanine3 tetrazine

Sulfo-Cyanine3 tetrazine

标签:Tetrazin,Copper free Click chemistr,sulfo-Cyanine3,sulfo-Cy3
货号 规格 价格 货期
113E0 1 mg 110.00$ in stock
213E0 5 mg 290.00$ in stock
313E0 10 mg 460.00$ in stock
413E0 25 mg 690.00$ in stock
513E0 50 mg 1270.00$ in stock
613E0 100 mg 1990.00$ in stock

Tetrazine – trans-cyclooctene ligation is among the fastest bioconjugation reactions known to date.

This water soluble sulfo-Cyanine3 derivative contains methyltetrazine moiety for the coupling with trans-cyclooctenes. Methyltetrazines possess optimal stability at physiological pH, while maintaining extremely high reactivity towards cyclooctenes.

The fluorophore is bright, photostable, and is also very well visible with naked eye.

四嗪-反式-环辛烯连接是迄今为止已知最快的生物偶联反应之一。

这种水溶性磺基-Cyanine3 衍生物含有甲基四嗪部分,用于与反式环辛烯偶联。 甲基四嗪在生理 pH 值下具有最佳稳定性,同时对环辛烯保持极高的反应性。

荧光团明亮、光稳定,而且肉眼也能很好地看到。

Sulfo-Cyanine3 tetrazine相关产品

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪(甲基四嗪)用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素(一种众所周知的亲和探针)进行点击化学标记的试剂。

AmdU (5-azidomethyl-2′-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide containing nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain promoted Click chemistry.

叠氮甲基脱氧尿苷 (AmdU) 是一种含有核苷的叠氮化物,可通过细胞聚合酶整合到新生 DNA 中。 以这种方式连接到 DNA 上的叠氮基可以随后通过铜催化或应变促进的点击化学被炔烃或环炔烃修饰。

General properties

Appearance: red powder 红色粉末
Molecular weight: 838.05
Molecular formula: C40H44KN7O7S2
IUPAC name: Potassium (E)-2-[(E)-3-{3,3-Dimethyl-1-[6-({[p-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl}amino)-6-oxohexyl]-5-(oxysulfonyl)-3H-indol-2-yl}-2-propenylidene]-1-methyl-3,3-dimethyl-5-indolinesulfonate
Solubility: soluble in water (0.43 M = 36 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cy® is a trademark of GE Healthcare.