BDP FL tetrazine

BDP FL tetrazine,与四嗪的逆电子需求 Diels-Alder 反应 (ied-DA) 是用于生物分子缀合的有前途的工具。 该反应发生在作为电子受体杂二烯的四嗪和应变的亲二烯体之间,例如反式-环辛烯、环丙烯或一些环辛炔。

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  • BDP FL tetrazine

BDP FL tetrazine

标签:BDP FL, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
114E0 1 mg 110.00$ in stock
214E0 5 mg 290.00$ in stock
414E0 25 mg 690.00$ in stock
514E0 50 mg 1270.00$ in stock
614E0 100 mg 1990.00$ in stock

Inverse electron demand Diels-Alder reaction (ied-DA) with tetrazines is a promising tool for the conjugation of biomolecules. The reaction takes place between tetrazine as an electron acceptor heterodiene, and a strained dienophile, such as trans-cyclooctene, cyclopropene, or some cyclooctynes.

Methyltetrazine provides greater stability in buffers than unsubstituted tetrazine. The rate of its reaction with cycloalkenes still beats almost all other conjugation reaction rates by a factor of magnitudes.

BDP FL is a bright dye for fluorescein (FAM) channel. Using BDP FL tetrazine, the dye can be conjugated with molecules bearing strained olefins.

与四嗪的逆电子需求 Diels-Alder 反应 (ied-DA) 是用于生物分子缀合的有前途的工具。 该反应发生在作为电子受体杂二烯的四嗪和应变的亲二烯体之间,例如反式-环辛烯、环丙烯或一些环辛炔。

与未取代的四嗪相比,甲基四嗪在缓冲液中的稳定性更高。 它与环烯烃的反应速率仍然比几乎所有其他共轭反应速率高出一个数量级。

BDP FL 是一种用于荧光素 (FAM) 通道的明亮染料。 使用 BDP FL 四嗪,染料可以与带有应变烯烃的分子结合。

Absorption and emission spectra of BODIPY FL

BDP FL tetrazine

BDP FL tetrazine相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cy5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性,推荐用于水环境中生物分子的标记。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯,用于标记蛋白质、肽和其他分子。

General properties

Appearance: red crystalline solid 红色结晶固体
Mass spec M+ increment: 447.2
Molecular weight: 475.3
CAS number: 2042193-77-9
Molecular formula: C24H24N7BF2O
Solubility: good in DCM, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027