CD81 (TAPA-1)是一种细胞表面蛋白，属于四跨蛋白超家族。CD81被确定为B淋巴细胞受体(BCR)的组成部分和丙型肝炎病毒的受体。重要的是，它存在于外泌体表面。
Application: FC
Clonality: Monoclonal
Conjugation: Tide Fluor™ 2SW
Host: Mouse
Purification: Ig-PG
Reactivity: Human
CD81 (TAPA-1) is a cell surface protein which belongs to the tetraspanin superfamily. CD81 is identified as a component of the B lymphocyte receptor (BCR) and as a receptor for the Hepatitis C Virus. Importantly, it is found on the surface of exosomes.
Exosomes are cell-derived vesicles bounded by a lipid bilayer membrane and exhibiting a diameter of 50 to 150 nm. They are secreted from cultured cells and are observed in body fluids such as saliva, blood, urine, amniotic fluid, malignant ascites. Recent studies indicate that exosomes contain various proteins and RNAs, suggesting a role in information transfer between cells.
This monoclonal antibody can be used to immunoprecipitate exosomes from serum and culture supernatants.
CD81 (TAPA-1)是一种细胞表面蛋白，属于四跨蛋白超家族。CD81被确定为B淋巴细胞受体(BCR)的组成部分和丙型肝炎病毒的受体。重要的是，它存在于外泌体表面。
外泌体是由脂质双分子层膜包围的细胞来源的囊泡，直径为50 – 150nm。它们由培养的细胞分泌，并在唾液、血液、尿液、羊水、恶性腹水等体液中观察到。最近的研究表明，外泌体含有各种蛋白质和rna，这表明外泌体在细胞之间的信息传递中起着重要作用。
该单克隆抗体可用于从血清和培养上清中免疫沉淀外泌体。