Cosmo Bio抗体,Cosmo Bio,Anti Myc Proto-Oncogene Protein (c-Myc) mAb (Clone 9E10),CAC-XIM-MA001
Application: FC, IP, IHC, WB, ChIP, ELISA
Clonality: Monoclonal
Host: Mouse
Purification: Ig-PG
Reactivity: Human
c-Myc is a very potent oncogene upregulated in various types of cancer. c-Myc, through its role as a transcription factor, alters the expression of hundreds of target genes, often oncogenes or tumor suppressors. Clone 9E10 recognizes recombinant proteins that incorporate the c-Myc epitope tag and detects human c-Myc proteins and peptides in random coil rather than alpha-helix structures.
References:
1) Mateos-Gomez et al. 2015. Nature. 518(7538):254-7. PMID: 25642960. (WB)
2) Zhang et al. 2014. Genes Dev. 28(8):829-34. PMID: 24736842. (ChIP)
3) Zhou et al. 2012. J Cell Biol. 196(2):203-11. PMID: 22270916. (IP, WB)
4) Mendes et al. 2010. J Biol Chem. 285(50):39117-26. PMID: 20937822. (IP, WB)
5) Royds et al. 1992. J Pathol. 166(3):225-33. PMID: 1381423. (IHC)
6) Spandidos et al. 1987. Anticancer Res. 7(6):1299-304. PMID: 3327455. (IHC)
7) Kari et al. 1986. J Virol. 60(2):345-52. PMID: 3021969. (IP)
8) Evan et al. 1985. Mol Cell Biol. 5(12):3610-6. PMID: 3915782. (WB)