ProSpec-CD2 Human GST,CD2 人重组PRO-468

ProSpec-CD2 Human GST,CD2 人重组PRO-468,p56lck、p59fyn、CD3eta 和 CD3epsilon 在 CD2 刺激后被酪氨酸磷酸化。 CD2 在 T 细胞活化、T 或 NK 细胞介导的细胞溶解、活化的外周 T 细胞凋亡和 T 细胞无能调节中发挥作用。

  • CD2 Human, GST

  • CD2 Human Recombinant, GST Tag
  • PRO-468

Catalogue number

PRO-468

Synonyms

T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, Erythrocyte receptor, Rosette receptor, CD2 antigen, CD2, T11, SRBC.

Introduction

CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 , and CD15s . p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
CD2 也称为 E-rosette 受体、T11 和淋巴细胞功能抗原 2,在 T 细胞、胸腺细胞和自然杀伤细胞亚群上表达。 人 CD2 作为绵羊红细胞、人 CD58 和 CD15s 的受体发挥作用。 p56lck、p59fyn、CD3eta 和 CD3epsilon 在 CD2 刺激后被酪氨酸磷酸化。 CD2 在 T 细胞活化、T 或 NK 细胞介导的细胞溶解、活化的外周 T 细胞凋亡和 T 细胞无能调节中发挥作用。

Description

CD2 Human Recombinant expressed in E.coli, shows a 46 kDa band on -PAGE.
The CD2 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

CD2 at 100µg/ml in 50mM Tris-HCl pH7.5 and 10Mm L-glutathione .

Stability

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.

Applications

• ELISA.
• Inhibition Assays.
• Western Blotting.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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