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CD3G Protein
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CD3 Gamma Human Recombinant
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PRO-1392
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Catalogue number
PRO-1392
Synonyms
T-cell surface glycoprotein CD3 gamma chain, CD3-GAMMA, T3G, CD3G.
Introduction
CD3-gamma polypeptide is encoded by CD3 Gamma which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, configures the T-cell receptor-CD3 complex. The T-cell receptor-CD3 complex takes part in coupling antigen recognition to numerous intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Deficiencies in this gene are associated with T cell immunodeficiency.
CD3-γ多肽由CD3 Gamma编码，CD3 Gamma与CD3-ε、-δ和-zeta以及T细胞受体α/β和γ/δ异二聚体一起构成T细胞受体-CD3复合物。 T 细胞受体-CD3 复合物参与将抗原识别与许多细胞内信号转导途径偶联。 编码ε、γ和δ多肽的基因位于11号染色体上的同一簇中。该基因的缺陷与T细胞免疫缺陷有关。
Description
CD3G Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids and having a molecular mass of 13.1kDa. CD3G is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CD3G protein solution containing 20mM Tris-HCl buffer , 0.4M urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
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CD3G Human