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CD4 Human, Sf9
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CD4 Human Recombinant, Sf9
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CYT-978
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Catalogue number
CYT-978
Synonyms
CD4 Molecule, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen , T-Cell Surface Glycoprotein CD4, CD4 Receptor, CD4 Antigen, CD4mut.
Introduction
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. Normally, about 65% of T cells in the blood are CD4+ . A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
CD4 是一种细胞表面糖蛋白，存在于成熟的辅助 T 细胞和未成熟的胸腺细胞以及单核细胞和巨噬细胞上。 正常情况下，血液中约 65% 的 T 细胞是 CD4+。 具有 CD4 或 CD8 的成熟 T 细胞，但不是两者兼有。 在发育的一个阶段，T 细胞会产生 CD4 和 CD8 受体，但它们最终会在胸腺中分化并变得更加特化。
Description
CD4 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 377 amino acids and having a molecular mass of 42.1kDa .
CD4 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
CD4 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Sf9 昆虫细胞中产生的 CD4 是单条糖基化多肽链，含有 377 个氨基酸，分子量为 42.1kDa。
CD4 在 C 末端用 6 个氨基酸的 His 标签表达，并通过专有色谱技术进行纯化。
CD4 在 C 末端用 6 个氨基酸的 His 标签表达，并通过专有色谱技术进行纯化。
Source
Sf9, Insect cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
CD4 a protein solution contains phosphate buffered saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
KKVVLGKKGD TVELTCTASQ KKSIQFHWKN SNQIKILGNQ GSFLTKGPSK LNDRADSRRS LWDQGNFPLI IKNLKIEDSD TYICEVEDQK EEVQLLVFGL TANSDTHLLQ GQSLTLTLES PPGSSPSVQC RSPRGKNIQG GKTLSVSQLE LQDSGTWTCT VLQNQKKVEF KIDIVVLAFQ KASSIVYKKE GEQVEFSFPL AFTVEKLTGS GELWWQAERA SSSKSWITFD LKNKEVSVKR VTQDPKLQMG KKLPLHLTLP QALPQYAGSG NLTLALEAKT GKLHQEVNLV VMRATQLQKN LTCEVWGPTS PKLMLSLKLE NKEAKVSKRE KAVWVLNPEA GMWQCLL GQVLLESNIK VLPTWSTPVQ PHHHHHH.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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CD4 Human