ProSpec-CD4 Human (203-317),CD-4人重组CYT-316

gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.

CD4, a single chain transmembrane glycoprotein, is found on a T cell subset representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

CD4 是一种单链跨膜糖蛋白，存在于代表 45% 外周血淋巴细胞的 T 细胞亚群上。 它也存在于 80% 的胸腺细胞上，而单核细胞上的水平较低。 它参与由 APC 识别与 MHC II 类一起呈递的抗原。 它作为 HIV 的受体。 CD4 抗体可识别识别 II 类抗原所需的 T 辅助细胞。 它与约 60% 的外周血 E 玫瑰花结阳性细胞发生反应，而与 E 细胞、单核细胞、粒细胞、EBV 转化的 B 细胞系和小鼠脾细胞的反应性可忽略不计。

CD-4 Human Recombinant His Tag protein encoding 203-317 amino acids.

Escherichia Coli.

Sterile lyophilized powder.

Each mg contains 1X PBS, 0.1% and 1mM DTT.

Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months.
Please avoid freeze-thaw cycles.

• Protein Assay.
• Antibody Production.
• Western Blotting.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

It is recommended to reconstitute the lyophilized CD-4 in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.