ProSpec,CD68 Human 38kDa,CD68 人重组PRO-293

Macrosialin, Gp110, CD68 antigen, CD68, SCARD1, DKFZp686M18236.

CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

CD68 编码一种 110-kD 的跨膜糖蛋白，在人类单核细胞和组织巨噬细胞中高度表达。 它是溶酶体/内体相关膜糖蛋白家族的成员。 该蛋白质主要定位于溶酶体和内体，其中一小部分循环到细胞表面。 它是一种 I 型整合膜蛋白，具有高度糖基化的细胞外结构域，可与组织和器官特异性凝集素或选择素结合。 该蛋白质也是清道夫受体家族的成员。 清道夫受体通常起到清除细胞碎片、促进吞噬作用和介导巨噬细胞募集和活化的作用。 选择性剪接导致多个转录本编码不同的亚型。

CD68 Human Recombinant full length expressed in E.coli, shows a 38 kDa band on -PAGE.
CD68 is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered clear solution.

CD68 at 100µg/1ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol.

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.