ProSpec,CD55 Human,CD55人重组PRO-2514

ProSpec,CD55 Human,CD55人重组PRO-2514,CD55 广泛分布于造血和非造血细胞中。 CD55 在肿瘤发生、细胞拯救和逃避细胞凋亡的自分泌环、细胞运动、侵袭性等方面具有关键作用。

  • CD55 Human

  • CD55 Human Recombinant
  • PRO-2514

Catalogue number

PRO-2514

Synonyms

CD55 Antigen, DAF, CD55 Molecule, CHAPLE, Cromer Blood Group Antigen, Complement Decay-Accelerating Factor, CROM.

Introduction

Decay-Accelerating Factor Isoform 1 or CD55, is a protein that attached to the cell membrane through glycophosphatidylinositol anchor. CD55 regulates the complement system in the outer membrane. The protein is a receptor to many types of enteroviruses such as coxsackieviruses. CD55 is widely scattered amidst hematopoietic & non-hematopoietic cells. The CD55 has a crucial part in tumorigenesis, autocrine loops for cell rescue and evasion of apoptosis, cell motility, invasiveness etc.

衰变加速因子 Isoform 1 或 CD55，是一种通过糖磷脂酰肌醇锚附着在细胞膜上的蛋白质。 CD55 调节外膜中的补体系统。 该蛋白是多种肠道病毒如柯萨奇病毒的受体。 CD55 广泛分布于造血和非造血细胞中。 CD55 在肿瘤发生、细胞拯救和逃避细胞凋亡的自分泌环、细胞运动、侵袭性等方面具有关键作用。

Description

CD55 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain and fused to a 9 aa His Tag at C-terminus containing a total of 328 amino acids and having a molecular mass of 36kDa. CD55 shows multiple bands between 40-57kDa on -PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD55 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.

For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

ADPDCGLPPD VPNAQPALEG RTSFPEDTVI TYKCEESFVK IPGEKDSVIC LKGSQWSDIE EFCNRSCEVP TRLNSASLKQ PYITQNYFPV GTVVEYECRP GYRREPSLSP KLTCLQNLKW STAVEFCKKK SCPNPGEIRN GQIDVPGGIL FGATISFSCN TGYKLFGSTS SFCLISGSSV QWSDPLPECR EIYCPAPPQI DNGIIQGERD HYGYRQSVTY ACNKGFTMIG EHSIYCTVNN DEGEWSGPPP ECRGKSLTSK VPPTVQKPTT VNVPTTEVSP TSQKTTTKTT TPNAQATRST PVSRTTKHFH ETTPNKGSGT TSHHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

  • CD55 Mouse