ProSpec,CD7 Human,CD7人重组PRO-1673

T细胞抗原CD7是一种I型跨膜糖蛋白，表达于多能造血细胞、几乎所有人类胸腺细胞和一些外周血T细胞上。 在某些生理条件下，人类 T 细胞亚群中缺少 CD7 分子。ProSpec,CD7 Human,CD7人重组PRO-1673

  • CD7 Human

  • CD7 Human Recombinant
  • PRO-1673

Catalogue number

PRO-1673

Synonyms

T-cell antigen CD7, GP40, LEU-9, Tp40, TP41, CD7, T-cell leukemia antigen, T-cell surface antigen Leu-9.

Introduction

T-cell antigen CD7 is a type I transmembrane glycoprotein which is expressed on pluripotential hemapoietic cells, nearly all human thymocytes and some peripheral blood T cells. The CD7 molecule is missing in a subset of human T cells under some physiologic conditions. An increase in CD7 negative T cells can be observed in a number of inflammatory skin diseases.
T细胞抗原CD7是一种I型跨膜糖蛋白，表达于多能造血细胞、几乎所有人类胸腺细胞和一些外周血T细胞上。 在某些生理条件下，人类 T 细胞亚群中缺少 CD7 分子。 在许多炎症性皮肤病中可以观察到 CD7 阴性 T 细胞的增加。

Description

CD7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 178 amino acids and having a molecular mass of 18.8 kDa.
CD7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD7 protein solution containing 20mM Tris-HCl buffer , 0.4M Urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSAQEVQQS PHCTTVPVGA SVNITCSTSG GLRGIYLRQL GPQPQDIIYY EDGVVPTTDR RFRGRIDFSG SQDNLTITMH RLQLSDTGTY TCQAITEVNV YGSGTLVLVT EEQSQGWHRC SDAPPRASAL PAPPTGSALP DPQTASALPD PPAASALP.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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