ProSpec,CD93 Mouse,CD93 小鼠重组PRO-2255

ProSpec,CD93 Mouse,CD93 小鼠重组PRO-2255,CD93 是 C1q、MBL2-甘露糖结合凝集素和 SPA-肺表面活性蛋白 A 的受体或更大受体复合物的元素。CD93 在与可溶性防御胶原相互作用时介导单核细胞和巨噬细胞吞噬作用的增强。

  • CD93 Mouse

  • CD93 Mouse Recombinant
  • PRO-2255

Catalogue number

PRO-2255

Synonyms

C1q/MBL/SPA receptor, C1qR, C1qRp, Cell surface antigen AA4, Complement, component 1 q subcomponent receptor 1, Lymphocyte antigen 68, Ly-68, CD93, Cd93.

Introduction

CD93, is a receptor or else an element of a larger receptor complex for C1q, MBL2-mannose-binding lectin and SPA-pulmonary surfactant protein A. CD93 mediates the enhancement of phagocytosis in monocytes as well as macrophages upon interaction with soluble defense collagens. CD93 takes part in the intercellular adhesion. Furthermore, CD93 was expressed on plasmablasts/plasma cells, including long-lived plasma cells which demonstrated decreased cell cycle activity, high levels of isotype-switched Ig secretion, as well as modification of the transcriptional network. CD93 is vital for the maintenance of plasma cells in bone marrow niches.
CD93 是 C1q、MBL2-甘露糖结合凝集素和 SPA-肺表面活性蛋白 A 的受体或更大受体复合物的元素。CD93 在与可溶性防御胶原相互作用时介导单核细胞和巨噬细胞吞噬作用的增强。 CD93参与细胞间粘附。 此外,CD93 在浆母细胞/浆细胞上表达,包括长寿浆细胞,其表现出细胞周期活性降低、同种型转换 Ig 分泌水平高以及转录网络的修饰。 CD93 对于维持骨髓壁龛中的浆细胞至关重要。

Description

CD93 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 558 amino acids and having a molecular mass of 60.1kDa. . CD93 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Sf9 昆虫细胞中产生的 CD93 是单条糖基化多肽链,含有 558 个氨基酸,分子量为 60.1kDa。 . CD93 在 C 末端用 8 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD93 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

ADSQAVVCEG TACYTAHWGK LSAAEAQHRC NENGGNLATV KSEEEARHVQ QALTQLLKTK APLEAKMGKF WIGLQREKGN CTYHDLPMRG FSWVGGGEDT AYSNWYKASK SSCIFKRCVS LILDLSLTPH PSHLPKWHES PCGTPEAPGN SIEGFLCKFN FKGMCRPLAL GGPGRVTYTT PFQATTSSLE AVPFASVANV ACGDEAKSET HYFLCNEKTP GIFHWGSSGP LCVSPKFGCS FNNGGCQQDC FEGGDGSFRC GCRPGFRLLD DLVTCASRNP CSSNPCTGGG MCHSVPLSEN YTCRCPSGYQ LDSSQVHCVD IDECQDSPCA QDCVNTLGSF HCECWVGYQP SGPKEEACED VDECAAANSP CAQGCINTDG SFYCSCKEGY IVSGEDSTQC EDIDECSDAR GNPCDSLCFN TDGSFRCGCP PGWELAPNGV FCSRGTVFSE LPARPPQKED NDDRKESTMP PTEMPSSPSG SKDVSNRAQT TGLFVQSDIP TASVPLEIEI PSEVSDVWFE LGTYLPTTSG HSKPTHEDSV SAHSDTDGQN LEHHHHHH.

Usage

ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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  • CD93 Human