ProSpec,CD3D Human,CD3D 人重组PRO-2539

CD3D，也称为 Delta 多肽，是一种单通道 1 型膜蛋白。 CD3D 与 CD3-zeta、CD3-γ、CD3-ε 和 T 细胞受体 α/β 和 γ/δ 异二聚体共同产生 T 细胞受体-CD3 复合物。ProSpec,CD3D Human,CD3D 人重组PRO-2539

  • CD3D Human

  • CD3D Human Recombinant
  • PRO-2539

Catalogue number

PRO-2539

Synonyms

CD3d Molecule, CD3d Antigen, Delta Polypeptide , CD3d Molecule, Delta , T-Cell Receptor T3 Delta Chain, T3D, T-Cell Surface Glycoprotein CD3 Delta Chain, CD3 Antigen, Delta Subunit, OKT3, Delta Chain, CD3d Antigen, CD3 Delta, CD3-DELTA, IMD19, CD3D.

Introduction

CD3D, also known as Delta Polypeptide , is a single-pass type 1 membrane protein. CD3D jointly with CD3-zeta, CD3-gamma, CD3-epsilon and the T-cell receptor alpha/beta and gamma/delta heterodimers, creates the T-cell receptor-CD3 complex. Once antigen presenting cells activate T-cell receptor , TCR-mediated signals are transferred through the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. Likewise, CD3D takes an important part in adaptive immune response and participates in thymocyte differentiation.

CD3D，也称为 Delta 多肽，是一种单通道 1 型膜蛋白。 CD3D 与 CD3-zeta、CD3-γ、CD3-ε 和 T 细胞受体 α/β 和 γ/δ 异二聚体共同产生 T 细胞受体-CD3 复合物。 一旦抗原呈递细胞激活 T 细胞受体，TCR 介导的信号就会通过 CD3 链 CD3D、CD3E、CD3G 和 CD3Z 传递通过细胞膜。 同样，CD3D 在适应性免疫反应中发挥重要作用并参与胸腺细胞分化。

Description

CD3D produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain and fused to a 239 aa hIgG-His-tag at C-terminus containing a total of 323 amino acids and having a molecular mass of 36.5kDa.
CD3D shows multiple bands between 40-57kDa on -PAGE, reducing conditions and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD3D protein solution contains 10% glycerol & Phosphate buffered saline .

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

FKIPIEELED RVFVNCNTSI TWVEGTVGTL LSDITRLDLG KRILDPRGIY RCNGTDIYKD KESTVQVHYR MCQSCVELDP ATVALEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSRDELTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGKHHH HHH

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.