ProSpec-CXCL16 Human/CHM-029,CXCL16 人重组/CHM-029

Chemokine Ligand 16, Scavenger Receptor For Phosphatidylserine And Oxidized Low Density Lipoprotein, Transmembrane Chemokine CXCL16, Small-Inducible Cytokine B16, CXC Chemokine Ligand 16, SR-PSOX, SRPSOX, C-X-C Motif Chemokine 16, CXCLG16, SCYB16, CXCL16.

CXC 趋化因子配体 16 是一种 I 型膜蛋白，在其细胞外区域包含一个不含 ELR 基序的 CXC 趋化因子结构域。 人和小鼠 CXCL16 共享 70% a.a. 其趋化因子结构域内的序列相似性和 49% 的总体 a.a. 序列同一性。 功能性 CXCL16 可以作为大约 35kDa 可溶性蛋白从细胞表面脱落。 CXCR6 是 CXCL16 的功能性受体。 CXCL16 充当巨噬细胞上的清道夫受体，与 OxLDL 特异性结合，提示 CXCL16 可能参与动脉粥样硬化等病理生理学。 此外，CXCL16 诱导强烈的趋化反应和钙动员。 CXCL16 与 CXCR6/Bonzo 结合。

CXCL16 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 89 amino acids and having a molecular mass of 10kDa.
The CXCL16 is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

CXCL16 protein was lyophilized from a 0.2µm filtered solution in PBS.

It is recommended to reconstitute the lyophilized CXCL16 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

冻干的 CXCL16 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重构后，CXCL16 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 97.0% as determined by -PAGE.

NEGSVTGSCY CGKRISP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP.

The ED₅₀, as measured by its ability to chemoattract mouse CXCR6-transfected mouse BaF3 cells, is less than 12ng/ml.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.